CN111315370A - 一种具有抗炎症性肠病作用的药物及其制备方法和应用 - Google Patents
一种具有抗炎症性肠病作用的药物及其制备方法和应用 Download PDFInfo
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- CN111315370A CN111315370A CN201880070394.4A CN201880070394A CN111315370A CN 111315370 A CN111315370 A CN 111315370A CN 201880070394 A CN201880070394 A CN 201880070394A CN 111315370 A CN111315370 A CN 111315370A
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Abstract
本申请提供了一种具有抗炎症性肠病作用的药物及其制备方法和应用，所述药物具有如式I或式II所示的结构，本申请所提供的药物及其药学上可接受的盐、溶剂合物、前药、互变异构体、立体化学异构体或药物组合物均对于炎症性肠病有良好的作用效果，可用于制备炎症性肠病的治疗药物，具有重要的临床意义和广泛的应用前景。
Description
PCT国内申请，说明书已公开。
Claims (15)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2018/097685 WO2020024078A1 (zh) | 2018-07-28 | 2018-07-28 | 一种具有抗炎症性肠病作用的药物及其制备方法和应用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN111315370A true CN111315370A (zh) | 2020-06-19 |
| CN111315370B CN111315370B (zh) | 2023-09-29 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201880070394.4A Active CN111315370B (zh) | 2018-07-28 | 2018-07-28 | 一种具有抗炎症性肠病作用的药物及其制备方法和应用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11602514B2 (zh) |
| EP (1) | EP3756660A4 (zh) |
| JP (2) | JP7332167B2 (zh) |
| CN (1) | CN111315370B (zh) |
| WO (1) | WO2020024078A1 (zh) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115505021B (zh) * | 2021-06-23 | 2023-08-15 | 沈阳药科大学 | 具有炎症性肠病治疗作用的乌苏酸衍生物及其制备方法和用途 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1646473A (zh) * | 2002-04-17 | 2005-07-27 | 北卡罗来纳查佩尔山大学 | 新的姜黄素类似物和其用途 |
| CN105198714A (zh) * | 2015-08-14 | 2015-12-30 | 浙江省中医药研究院 | 杨梅醇衍生物及其制备方法和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4343268B2 (ja) | 2007-12-18 | 2009-10-14 | 明治製菓株式会社 | 炎症性腸疾患の予防または治療剤 |
| US8940945B2 (en) | 2010-07-23 | 2015-01-27 | University Of South Florida | Materials and methods for reduction of protein tau and treatment of neurodegenerative diseases |
| CN102552243A (zh) | 2012-02-29 | 2012-07-11 | 浙江省中医药研究院 | 杨梅醇和/或杨梅酮在制备抗肿瘤药物中的应用 |
| CN108434127B (zh) | 2018-06-14 | 2020-01-17 | 苏州沪云肿瘤研究中心股份有限公司 | 一种杨梅醇和/或杨梅酮在制备具有预防和/或治疗炎症性肠病的药物中的应用 |
-
2018
- 2018-07-28 CN CN201880070394.4A patent/CN111315370B/zh active Active
- 2018-07-28 WO PCT/CN2018/097685 patent/WO2020024078A1/zh unknown
- 2018-07-28 JP JP2020524059A patent/JP7332167B2/ja active Active
- 2018-07-28 US US17/043,428 patent/US11602514B2/en active Active
- 2018-07-28 EP EP18928374.0A patent/EP3756660A4/en active Pending
-
2022
- 2022-03-24 JP JP2022048441A patent/JP2022089845A/ja active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1646473A (zh) * | 2002-04-17 | 2005-07-27 | 北卡罗来纳查佩尔山大学 | 新的姜黄素类似物和其用途 |
| CN105198714A (zh) * | 2015-08-14 | 2015-12-30 | 浙江省中医药研究院 | 杨梅醇衍生物及其制备方法和应用 |
Non-Patent Citations (5)
| Title |
|---|
| DECNE. KO, HA NA 等: "Anti-Inflammatory Constituents from the Branches of Pourthiaea villosa (Thunb.)", 《BULLETIN OF THE KOREAN CHEMICAL SOCIETY》 * |
| IBRAHIM, SABRIN R. M. 等: "Alnuheptanoid B: a new cyclic diarylheptanoid from Alnus japonica stem bark.", 《RECORDS OF NATURAL PRODUCTS》 * |
| WHITING, DONALD A等: "Cyclization of 1, 7-diarylheptanoids through oxidative, reductive, and photochemical radical processes: total synthesis of the m, m-bridged biaryls myricanone and (±)-myricanol, and a related diaryl ether.", 《TETRAHEDRON LETTERS》 * |
| WHITING, DONALD A等: "Total syntheses of the meta, meta-bridged biphenyls (±)-myricanol and myricanone, and of an isomeric biphenyl ether, a 14-oxa[7, l]metaparacyclophane.", 《JOURNAL OF THE CHEMICAL SOCIETY, PERKIN TRANSACTIONS 1: ORGANIC AND BIO-ORGANIC CHEMISTRY (1972-1999)》 * |
| YOSHIMURA, MORIO等: "Diarylheptanoid sulfates and related compounds from Myrica rubra bark.", 《JOURNAL OF NATURAL PRODUCTS》 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3756660A1 (en) | 2020-12-30 |
| US20210015780A1 (en) | 2021-01-21 |
| US11602514B2 (en) | 2023-03-14 |
| JP7332167B2 (ja) | 2023-08-23 |
| EP3756660A4 (en) | 2021-10-13 |
| JP2021501171A (ja) | 2021-01-14 |
| JP2022089845A (ja) | 2022-06-16 |
| CN111315370B (zh) | 2023-09-29 |
| WO2020024078A1 (zh) | 2020-02-06 |
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