CN111282026A - Sexual lubricant capable of quickly killing various venereal disease pathogens - Google Patents
Sexual lubricant capable of quickly killing various venereal disease pathogens Download PDFInfo
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Abstract
The invention provides a sexual lubricant capable of quickly killing various venereal pathogens, which relates to the field of human body lubricants and comprises the following components in parts by weight: 4-10 parts of amino acid modified chitosan, 20-40 parts of 1, 3-butanediol, 6-10 parts of hydrogenated castor oil polyoxyethylene ether, 1-3 parts of carbomer, 0.1-1 part of triethanolamine, 1-5 parts of methylisothiazolinone, 0.1-0.5 part of iodopropynyl butylcarbamate, 6-8 parts of sodium carboxymethylcellulose, 15-20 parts of humifuse euphorbia herb extract, 15-20 parts of aloe extract, 15-20 parts of Chinese honeylocust fruit extract, 15-20 parts of brucea javanica fruit extract, 10-15 parts of propylene glycol and 800-880 parts of deionized water, can eliminate dryness caused by female vaginal secretion reduction, improve the lubricating effect during sexual intercourse, increase the sexual pleasure, ensure more harmonious sexual life, be beneficial to the improvement of the feelings of couples and protect the female vaginal hygiene during sexual life, avoid various gynecological inflammations caused by the dirty life.
Description
Technical Field
The invention relates to the field of human body lubricants, in particular to a sexual lubricant capable of quickly killing various venereal disease pathogens.
Background
The sexual lubricant is different from a lubricant used by machinery, is especially designed for sexual intercourse of men and women, has wide applicability and higher safety, and not only can increase the lubricating effect and improve the sexual pleasure, but also can lead the sexual life to be more harmonious and improve the feelings among couples; meanwhile, the skin injury is reduced, and the corrosion chance of harmful microorganisms such as bacteria, viruses and the like to the human body is reduced; effectively reduces the damage of the condom and reduces the probability of accidental pregnancy. The early sexual intercourse lubricant takes glycerin and hydrophilic substances as main components, and is improved later by adding sodium hyaluronate, ethyl cellulose, carbomer and other components, so that the viscosity is reduced, the pH value is balanced, the sexual intercourse lubricant is similar to the body fluid of a human body as much as possible, and the occurrence probability of allergic symptoms is reduced.
The existing sexual lubricant is divided into aqueous sexual lubricant, oil sexual lubricant and silicon-containing sexual lubricant, and the aqueous sexual lubricant is made of water and fiber and is accepted by the body surface most. It is easily lost after drying, but it recovers its effect after replenishing moisture. Therefore, it is often used as a sex lubricant, and an oil-based sexual lubricant is made of mineral oil, unlike water-based, and does not react with body fluid, thus having a long-lasting effect. The lubrication effect is poor. Such lubricants are long lasting and difficult to clean. Is commonly used in medical applications. Oil-based lubricants can impair the effectiveness of condoms, adherence of lubricants to body surfaces tends to increase bacterial infections, silicon-containing aqueous lubricant silicon and oil mixtures. It is easy to react with silicon-containing materials, such as silica gel, and at present, the aqueous sexual lubricant is most widely used, but has poor effect of killing venereal pathogens.
Chinese patent CN103405594A discloses a water-soluble human body lubricant, a preparation method thereof and a condom adopting the lubricant, wherein the water-soluble human body lubricant comprises the following components in percentage by weight: glycerol: 20-40%, tween-20: 1-5%, sodium hyaluronate: 0.02-0.2%, rose essential oil: 0.2-0.8%, aloe essential oil: 0.5-1.5%, pharmaceutical grade water soluble azone: 0.5-2% and the balance of water. The human body lubricant can be mutually dissolved with normal secretion of a human body, has no greasy feeling, has the pH value consistent with the pH value of the normal physiological environment of a female vagina, has good lubricating effect, is beneficial to enhancing the sexual life interest, supplementing nutrient substances required by the skin and is beneficial to the female health.
Disclosure of Invention
Technical problem to be solved
Aiming at the defects of the prior art, the invention provides a sexual lubricant which can quickly kill a plurality of venereal pathogens.
(II) technical scheme
In order to achieve the purpose, the invention is realized by the following technical scheme:
a sexual lubricant capable of quickly killing a plurality of venereal pathogens comprises the following components in parts by weight: 4-10 parts of amino acid modified chitosan, 20-40 parts of 1, 3-butanediol, 6-10 parts of hydrogenated castor oil polyoxyethylene ether, 1-3 parts of carbomer, 0.1-1 part of triethanolamine, 1-5 parts of methylisothiazolinone, 0.1-0.5 part of iodopropynyl alcohol butyl carbamate, 6-8 parts of sodium carboxymethylcellulose, 15-20 parts of humifuse euphorbia herb extract, 15-20 parts of aloe extract, 15-20 parts of Chinese honeylocust fruit extract, 15-20 parts of brucea javanica fruit extract, 10-15 parts of propylene glycol and 800-880 parts of deionized water.
Further, the paint comprises the following components in parts by weight: 5 parts of amino acid modified chitosan, 30 parts of 1, 3-butanediol, 7 parts of hydrogenated castor oil polyoxyethylene ether, 1.5 parts of carbomer, 0.2 part of triethanolamine, 2 parts of methylisothiazolinone, 0.5 part of iodopropynyl butylcarbamate, 7 parts of sodium carboxymethylcellulose, 18 parts of humifuse euphorbia extract, 16 parts of aloe extract, 20 parts of Chinese honeylocust fruit extract, 20 parts of brucea javanica extract, 11 parts of propylene glycol and 850 parts of deionized water.
Further, the paint comprises the following components in parts by weight: 10 parts of amino acid modified chitosan, 25 parts of 1, 3-butanediol, 8 parts of hydrogenated castor oil polyoxyethylene ether, 3 parts of carbomer, 0.2 part of triethanolamine, 3 parts of methylisothiazolinone, 0.2 part of iodopropynyl butylcarbamate, 7 parts of sodium carboxymethylcellulose, 18 parts of humifuse euphorbia extract, 20 parts of aloe extract, 16 parts of saponin extract, 20 parts of brucea javanica extract, 12 parts of propylene glycol and 810 parts of deionized water.
Further, the preparation method of the amino acid modified chitosan comprises the following steps:
adding chitosan into deionized water, dispersing for 10-20min by ultrasonic oscillation, adding L-arginine, 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride and N-hydroxy-succinimide, adjusting the pH of the system to 4-5 by using a hydrochloric acid solution, stirring, heating to 30-40 ℃, reacting for 10-15h, adjusting the pH of the system to 9-10 by using a sodium hydroxide solution, adding reactants into a dialysis bag, dialyzing for 5-10d, reducing the temperature to 1-5 ℃ after reduced pressure concentration, and performing suction filtration to obtain the amino acid modified chitosan.
Furthermore, the mass concentration of the hydrochloric acid solution is 10-18%, and the mass concentration of the sodium hydroxide solution is 15-30%.
Further, the molar mass ratio of the chitosan to the L-arginine to the 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride to the N-hydroxy-succinimide is 1: 1.2-1.5: 0.01-0.05: 0.5-1.
Further, the preparation method comprises the following specific steps:
adding the humifuse euphorbia extract, the aloe extract, the saponin extract and the brucea javanica extract into deionized water, heating to 50-70 ℃, ultrasonically vibrating until the mixture is dissolved, sequentially adding amino acid modified chitosan, 1, 3-butanediol, hydrogenated castor oil polyoxyethylene ether, carbomer, triethanolamine, methylisothiazolinone, iodopropynyl butylcarbamate and propylene glycol, mechanically stirring for 20-40min at 800r/min with 500-dose, transferring to a high-speed shearing dispersion machine, carrying out high-speed shearing dispersion for 20-40min at 2000r/min, finally adding sodium carboxymethylcellulose, carrying out high-speed shearing dispersion for 5-10min at 2500r/min with 2300-dose, sterilizing and subpackaging.
(III) advantageous effects
The invention provides a sexual lubricant capable of quickly killing a plurality of venereal pathogens, which has the following beneficial effects:
the sexual lubricant has wide applicability, can eliminate dryness caused by reduction of female vaginal secretion, improves the lubricating effect during sexual intercourse, increases sexual pleasure, enables sexual life to be more harmonious, and is beneficial to improvement of feelings of couples.
Detailed Description
Example 1:
a sexual lubricant capable of quickly killing a plurality of venereal pathogens comprises the following components in parts by weight: 5 parts of amino acid modified chitosan, 30 parts of 1, 3-butanediol, 7 parts of hydrogenated castor oil polyoxyethylene ether, 1.5 parts of carbomer, 0.2 part of triethanolamine, 2 parts of methylisothiazolinone, 0.5 part of iodopropynyl butylcarbamate, 7 parts of sodium carboxymethylcellulose, 18 parts of humifuse euphorbia extract, 16 parts of aloe extract, 20 parts of Chinese honeylocust fruit extract, 20 parts of brucea javanica extract, 11 parts of propylene glycol and 850 parts of deionized water.
The preparation method of the amino acid modified chitosan comprises the following steps:
adding chitosan into deionized water, dispersing for 15min by ultrasonic oscillation, adding L-arginine, 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride and N-hydroxy-succinimide, wherein the molar mass ratio of the chitosan to the L-arginine to the 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride to the N-hydroxy-succinimide is 1: 1.4: 0.02: 0.8, regulating the pH of the system to 4-5 by using a hydrochloric acid solution with the mass concentration of 16%, stirring and heating to 35 ℃, reacting for 12 hours, regulating the pH of the system to 9-10 by using a sodium hydroxide solution with the mass concentration of 20%, adding reactants into a dialysis bag, dialyzing for 8 days, reducing the temperature to 2 ℃ after reduced pressure concentration, and performing suction filtration to obtain the amino acid modified chitosan.
The preparation method of the sexual intercourse lubricant capable of quickly killing a plurality of venereal pathogens comprises the following steps:
adding herba Euphorbiae Humifusae extract, Aloe extract, fructus Gleditsiae Abnormalis extract, and fructus Bruceae extract into deionized water, heating to 55 deg.C, ultrasonically vibrating to dissolve, sequentially adding amino acid modified chitosan, 1, 3-butanediol, hydrogenated castor oil polyoxyethylene ether, carbomer, triethanolamine, methylisothiazolinone, iodopropynyl alcohol butyl carbamate, and propylene glycol, mechanically stirring at 600r/min for 25min, transferring to high-speed shearing disperser, shearing at 1800r/min for 20min, adding carboxymethylcellulose sodium, shearing at 2400r/min for 6min, sterilizing, and packaging.
Example 2:
a sexual lubricant capable of quickly killing a plurality of venereal pathogens comprises the following components in parts by weight: 10 parts of amino acid modified chitosan, 25 parts of 1, 3-butanediol, 8 parts of hydrogenated castor oil polyoxyethylene ether, 3 parts of carbomer, 0.2 part of triethanolamine, 3 parts of methylisothiazolinone, 0.2 part of iodopropynyl butylcarbamate, 7 parts of sodium carboxymethylcellulose, 18 parts of humifuse euphorbia extract, 20 parts of aloe extract, 16 parts of saponin extract, 20 parts of brucea javanica extract, 12 parts of propylene glycol and 810 parts of deionized water.
The preparation method of the amino acid modified chitosan comprises the following steps:
adding chitosan into deionized water, dispersing for 18min by ultrasonic oscillation, adding L-arginine, 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride and N-hydroxy-succinimide, wherein the molar mass ratio of the chitosan to the L-arginine to the 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride to the N-hydroxy-succinimide is 1: 1.5: 0.02: 1, regulating the pH of a system to 4-5 by using a hydrochloric acid solution with the mass concentration of 12%, stirring and heating to 30 ℃, reacting for 14h, regulating the pH of the system to 9-10 by using a sodium hydroxide solution with the mass concentration of 30%, adding reactants into a dialysis bag, dialyzing for 10d, reducing the temperature to 2 ℃ after reduced pressure concentration, and performing suction filtration to obtain the amino acid modified chitosan.
The preparation method of the sexual intercourse lubricant capable of quickly killing a plurality of venereal pathogens comprises the following steps:
adding herba Euphorbiae Humifusae extract, Aloe extract, fructus Gleditsiae Abnormalis extract, and fructus Bruceae extract into deionized water, heating to 60 deg.C, ultrasonically vibrating to dissolve, sequentially adding amino acid modified chitosan, 1, 3-butanediol, hydrogenated castor oil polyoxyethylene ether, carbomer, triethanolamine, methylisothiazolinone, iodopropynyl alcohol butyl carbamate, and propylene glycol, mechanically stirring at 500r/min for 30min, transferring to high-speed shearing disperser, shearing at 1800r/min for 40min, adding carboxymethylcellulose sodium, shearing at 2500r/min for 7min, sterilizing, and packaging.
Example 3:
a sexual lubricant capable of quickly killing a plurality of venereal pathogens comprises the following components in parts by weight: 5 parts of amino acid modified chitosan, 35 parts of 1, 3-butanediol, 8 parts of hydrogenated castor oil polyoxyethylene ether, 1.5 parts of carbomer, 0.3 part of triethanolamine, 4 parts of methylisothiazolinone, 0.2 part of iodopropynyl butylcarbamate, 7 parts of sodium carboxymethylcellulose, 18 parts of humifuse euphorbia extract, 20 parts of aloe extract, 16 parts of saponin extract, 20 parts of brucea javanica extract, 14 parts of propylene glycol and 860 parts of deionized water.
The preparation method of the amino acid modified chitosan comprises the following steps:
adding chitosan into deionized water, dispersing for 20min by ultrasonic oscillation, adding L-arginine, 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride and N-hydroxy-succinimide, wherein the molar mass ratio of the chitosan to the L-arginine to the 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride to the N-hydroxy-succinimide is 1: 1.5: 0.03: 0.8, regulating the pH of the system to 4-5 by using a hydrochloric acid solution with the mass concentration of 18%, stirring and heating to 40 ℃, reacting for 12 hours, regulating the pH of the system to 9-10 by using a sodium hydroxide solution with the mass concentration of 18%, adding reactants into a dialysis bag, dialyzing for 10 days, reducing the temperature to 4 ℃ after reduced pressure concentration, and performing suction filtration to obtain the amino acid modified chitosan.
The preparation method of the sexual intercourse lubricant capable of quickly killing a plurality of venereal pathogens comprises the following steps:
adding herba Euphorbiae Humifusae extract, Aloe extract, fructus Gleditsiae Abnormalis extract, and fructus Bruceae extract into deionized water, heating to 70 deg.C, ultrasonically vibrating to dissolve, sequentially adding amino acid modified chitosan, 1, 3-butanediol, hydrogenated castor oil polyoxyethylene ether, carbomer, triethanolamine, methylisothiazolinone, iodopropynyl alcohol butyl carbamate, and propylene glycol, mechanically stirring at 800r/min for 30min, transferring to high-speed shearing disperser, shearing at 1800r/min for 30min, adding carboxymethylcellulose sodium, shearing at 2400r/min for 5min, sterilizing, and packaging.
Example 4:
a sexual lubricant capable of quickly killing a plurality of venereal pathogens comprises the following components in parts by weight: 10 parts of amino acid modified chitosan, 30 parts of 1, 3-butanediol, 10 parts of hydrogenated castor oil polyoxyethylene ether, 2 parts of carbomer, 0.5 part of triethanolamine, 2 parts of methylisothiazolinone, 0.3 part of iodopropynyl butylcarbamate, 8 parts of sodium carboxymethylcellulose, 18 parts of humifuse euphorbia herb extract, 20 parts of aloe extract, 18 parts of Chinese honeylocust fruit extract, 20 parts of brucea javanica extract, 10 parts of propylene glycol and 870 parts of deionized water.
The preparation method of the amino acid modified chitosan comprises the following steps:
adding chitosan into deionized water, dispersing for 20min by ultrasonic oscillation, adding L-arginine, 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride and N-hydroxy-succinimide, wherein the molar mass ratio of the chitosan to the L-arginine to the 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride to the N-hydroxy-succinimide is 1: 1.3: 0.01: 0.8, regulating the pH of the system to 4-5 by using a hydrochloric acid solution with the mass concentration of 10%, stirring and heating to 35 ℃, reacting for 15h, regulating the pH of the system to 9-10 by using a sodium hydroxide solution with the mass concentration of 18%, adding reactants into a dialysis bag, dialyzing for 10d, reducing the temperature to 2 ℃ after reduced pressure concentration, and performing suction filtration to obtain the amino acid modified chitosan.
The preparation method of the sexual intercourse lubricant capable of quickly killing a plurality of venereal pathogens comprises the following steps:
adding herba Euphorbiae Humifusae extract, Aloe extract, fructus Gleditsiae Abnormalis extract, and fructus Bruceae extract into deionized water, heating to 70 deg.C, ultrasonically vibrating to dissolve, sequentially adding amino acid modified chitosan, 1, 3-butanediol, hydrogenated castor oil polyoxyethylene ether, carbomer, triethanolamine, methylisothiazolinone, iodopropynyl alcohol butyl carbamate, and propylene glycol, mechanically stirring at 500r/min for 40min, transferring to high-speed shearing disperser, shearing at 1700r/min for 40min, adding carboxymethylcellulose sodium, shearing at 2500r/min for 8min, sterilizing, and packaging.
Example 5:
a sexual lubricant capable of quickly killing a plurality of venereal pathogens comprises the following components in parts by weight: 4 parts of amino acid modified chitosan, 20 parts of 1, 3-butanediol, 6 parts of hydrogenated castor oil polyoxyethylene ether, 1 part of carbomer, 0.1 part of triethanolamine, 1 part of methylisothiazolinone, 0.1 part of iodopropynyl butylcarbamate, 6 parts of sodium carboxymethylcellulose, 15 parts of humifuse euphorbia herb extract, 15 parts of aloe extract, 15 parts of Chinese honeylocust fruit extract, 15 parts of brucea javanica extract, 10 parts of propylene glycol and 800 parts of deionized water.
The preparation method of the amino acid modified chitosan comprises the following steps:
adding chitosan into deionized water, dispersing for 10min by ultrasonic oscillation, adding L-arginine, 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride and N-hydroxy-succinimide, wherein the molar mass ratio of the chitosan to the L-arginine to the 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride to the N-hydroxy-succinimide is 1: 1.2: 0.01: 0.5, regulating the pH of the system to 4-5 by using a hydrochloric acid solution with the mass concentration of 10%, stirring and heating to 30 ℃, reacting for 10 hours, regulating the pH of the system to 9-10 by using a sodium hydroxide solution with the mass concentration of 15%, adding reactants into a dialysis bag, dialyzing for 5 days, reducing the temperature to 1 ℃ after reduced pressure concentration, and performing suction filtration to obtain the amino acid modified chitosan.
The preparation method of the sexual intercourse lubricant capable of quickly killing a plurality of venereal pathogens comprises the following steps:
adding herba Euphorbiae Humifusae extract, Aloe extract, fructus Gleditsiae Abnormalis extract, and fructus Bruceae extract into deionized water, heating to 50 deg.C, ultrasonically vibrating to dissolve, sequentially adding amino acid modified chitosan, 1, 3-butanediol, hydrogenated castor oil polyoxyethylene ether, carbomer, triethanolamine, methylisothiazolinone, iodopropynyl alcohol butyl carbamate, and propylene glycol, mechanically stirring at 500r/min for 20min, transferring to high-speed shearing disperser, shearing at 1500r/min for 20min, adding carboxymethylcellulose sodium, shearing at 2300r/min for 5min, sterilizing, and packaging.
Example 6:
a sexual lubricant capable of quickly killing a plurality of venereal pathogens comprises the following components in parts by weight: 10 parts of amino acid modified chitosan, 40 parts of 1, 3-butanediol, 10 parts of hydrogenated castor oil polyoxyethylene ether, 3 parts of carbomer, 1 part of triethanolamine, 5 parts of methylisothiazolinone, 0.5 part of iodopropynyl butylcarbamate, 8 parts of sodium carboxymethylcellulose, 20 parts of humifuse euphorbia extract, 20 parts of aloe extract, 20 parts of saponin extract, 20 parts of brucea javanica extract, 15 parts of propylene glycol and 880 parts of deionized water.
The preparation method of the amino acid modified chitosan comprises the following steps:
adding chitosan into deionized water, dispersing for 20min by ultrasonic oscillation, adding L-arginine, 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride and N-hydroxy-succinimide, wherein the molar mass ratio of the chitosan to the L-arginine to the 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride to the N-hydroxy-succinimide is 1: 1.5: 0.05: 1, regulating the pH of a system to 4-5 by using a hydrochloric acid solution with the mass concentration of 18%, stirring and heating to 40 ℃, reacting for 15h, regulating the pH of the system to 9-10 by using a sodium hydroxide solution with the mass concentration of 30%, adding reactants into a dialysis bag, dialyzing for 10d, reducing the temperature to 5 ℃ after reduced pressure concentration, and performing suction filtration to obtain the amino acid modified chitosan.
The preparation method of the sexual intercourse lubricant capable of quickly killing a plurality of venereal pathogens comprises the following steps:
adding herba Euphorbiae Humifusae extract, Aloe extract, fructus Gleditsiae Abnormalis extract, and fructus Bruceae extract into deionized water, heating to 70 deg.C, ultrasonically vibrating to dissolve, sequentially adding amino acid modified chitosan, 1, 3-butanediol, hydrogenated castor oil polyoxyethylene ether, carbomer, triethanolamine, methylisothiazolinone, iodopropynyl alcohol butyl carbamate, and propylene glycol, mechanically stirring at 800r/min for 40min, transferring to high-speed shearing disperser, shearing at 2000r/min for 40min, adding carboxymethylcellulose sodium, shearing at 2500r/min for 10min, sterilizing, and packaging.
Example 7:
a sexual lubricant capable of quickly killing a plurality of venereal pathogens comprises the following components in parts by weight: 4 parts of amino acid modified chitosan, 40 parts of 1, 3-butanediol, 6 parts of hydrogenated castor oil polyoxyethylene ether, 3 parts of carbomer, 0.1 part of triethanolamine, 5 parts of methylisothiazolinone, 0.1 part of iodopropynyl butylcarbamate, 8 parts of sodium carboxymethylcellulose, 15 parts of humifuse euphorbia herb extract, 20 parts of aloe extract, 15 parts of Chinese honeylocust fruit extract, 20 parts of brucea javanica extract, 10 parts of propylene glycol and 880 parts of deionized water.
The preparation method of the amino acid modified chitosan comprises the following steps:
adding chitosan into deionized water, dispersing for 10min by ultrasonic oscillation, adding L-arginine, 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride and N-hydroxy-succinimide, wherein the molar mass ratio of the chitosan to the L-arginine to the 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride to the N-hydroxy-succinimide is 1: 1.5: 0.01: 1, regulating the pH of a system to 4-5 by using a hydrochloric acid solution with the mass concentration of 10%, stirring and heating to 40 ℃, reacting for 10 hours, regulating the pH of the system to 9-10 by using a sodium hydroxide solution with the mass concentration of 30%, adding reactants into a dialysis bag, dialyzing for 5 days, reducing the temperature to 5 ℃ after reduced pressure concentration, and performing suction filtration to obtain the amino acid modified chitosan.
The preparation method of the sexual intercourse lubricant capable of quickly killing a plurality of venereal pathogens comprises the following steps:
adding herba Euphorbiae Humifusae extract, Aloe extract, fructus Gleditsiae Abnormalis extract, and fructus Bruceae extract into deionized water, heating to 50 deg.C, ultrasonically vibrating to dissolve, sequentially adding amino acid modified chitosan, 1, 3-butanediol, hydrogenated castor oil polyoxyethylene ether, carbomer, triethanolamine, methylisothiazolinone, iodopropynyl alcohol butyl carbamate, and propylene glycol, mechanically stirring at 800r/min for 20min, transferring to high-speed shearing disperser, shearing at 2000r/min for 20min, adding carboxymethylcellulose sodium, shearing at 2500r/min for 5min, sterilizing, and packaging.
Example 8:
a sexual lubricant capable of quickly killing a plurality of venereal pathogens comprises the following components in parts by weight: 10 parts of amino acid modified chitosan, 20 parts of 1, 3-butanediol, 6 parts of hydrogenated castor oil polyoxyethylene ether, 3 parts of carbomer, 0.1 part of triethanolamine, 5 parts of methylisothiazolinone, 0.1 part of iodopropynyl butylcarbamate, 8 parts of sodium carboxymethylcellulose, 15 parts of humifuse euphorbia extract, 20 parts of aloe extract, 15 parts of Chinese honeylocust fruit extract, 20 parts of brucea javanica extract, 10 parts of propylene glycol and 880 parts of deionized water.
The preparation method of the amino acid modified chitosan comprises the following steps:
adding chitosan into deionized water, dispersing for 20min by ultrasonic oscillation, adding L-arginine, 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride and N-hydroxy-succinimide, wherein the molar mass ratio of the chitosan to the L-arginine to the 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride to the N-hydroxy-succinimide is 1: 1.2: 0.05: 0.5, regulating the pH of the system to 4-5 by using a hydrochloric acid solution with the mass concentration of 18%, stirring and heating to 30 ℃, reacting for 15h, regulating the pH of the system to 9-10 by using a sodium hydroxide solution with the mass concentration of 15%, adding reactants into a dialysis bag, dialyzing for 10d, reducing the temperature to 1 ℃ after reduced pressure concentration, and performing suction filtration to obtain the amino acid modified chitosan.
The preparation method of the sexual intercourse lubricant capable of quickly killing a plurality of venereal pathogens comprises the following steps:
adding herba Euphorbiae Humifusae extract, Aloe extract, fructus Gleditsiae Abnormalis extract, and fructus Bruceae extract into deionized water, heating to 70 deg.C, ultrasonically vibrating to dissolve, sequentially adding amino acid modified chitosan, 1, 3-butanediol, hydrogenated castor oil polyoxyethylene ether, carbomer, triethanolamine, methylisothiazolinone, iodopropynyl alcohol butyl carbamate, and propylene glycol, mechanically stirring at 500r/min for 40min, transferring to high-speed shearing disperser, shearing at 1500r/min for 40min, adding carboxymethylcellulose sodium, shearing at 2300r/min for 10min, sterilizing, and packaging.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.
The above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.
Claims (7)
1. The sexual lubricant capable of quickly killing a plurality of venereal pathogens is characterized by comprising the following components in parts by weight: 4-10 parts of amino acid modified chitosan, 20-40 parts of 1, 3-butanediol, 6-10 parts of hydrogenated castor oil polyoxyethylene ether, 1-3 parts of carbomer, 0.1-1 part of triethanolamine, 1-5 parts of methylisothiazolinone, 0.1-0.5 part of iodopropynyl alcohol butyl carbamate, 6-8 parts of sodium carboxymethylcellulose, 15-20 parts of humifuse euphorbia herb extract, 15-20 parts of aloe extract, 15-20 parts of Chinese honeylocust fruit extract, 15-20 parts of brucea javanica fruit extract, 10-15 parts of propylene glycol and 800-880 parts of deionized water.
2. The sexual lubricant of claim 1, which comprises the following components in parts by weight: 5 parts of amino acid modified chitosan, 30 parts of 1, 3-butanediol, 7 parts of hydrogenated castor oil polyoxyethylene ether, 1.5 parts of carbomer, 0.2 part of triethanolamine, 2 parts of methylisothiazolinone, 0.5 part of iodopropynyl butylcarbamate, 7 parts of sodium carboxymethylcellulose, 18 parts of humifuse euphorbia extract, 16 parts of aloe extract, 20 parts of Chinese honeylocust fruit extract, 20 parts of brucea javanica extract, 11 parts of propylene glycol and 850 parts of deionized water.
3. The sexual lubricant of claim 1, which comprises the following components in parts by weight: 10 parts of amino acid modified chitosan, 25 parts of 1, 3-butanediol, 8 parts of hydrogenated castor oil polyoxyethylene ether, 3 parts of carbomer, 0.2 part of triethanolamine, 3 parts of methylisothiazolinone, 0.2 part of iodopropynyl butylcarbamate, 7 parts of sodium carboxymethylcellulose, 18 parts of humifuse euphorbia extract, 20 parts of aloe extract, 16 parts of saponin extract, 20 parts of brucea javanica extract, 12 parts of propylene glycol and 810 parts of deionized water.
4. The sexual lubricant of claim 1, wherein the amino acid-modified chitosan is prepared by the following steps:
adding chitosan into deionized water, dispersing for 10-20min by ultrasonic oscillation, adding L-arginine, 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride and N-hydroxy-succinimide, adjusting the pH of the system to 4-5 by using a hydrochloric acid solution, stirring, heating to 30-40 ℃, reacting for 10-15h, adjusting the pH of the system to 9-10 by using a sodium hydroxide solution, adding reactants into a dialysis bag, dialyzing for 5-10d, reducing the temperature to 1-5 ℃ after reduced pressure concentration, and performing suction filtration to obtain the amino acid modified chitosan.
5. The sexual lubricant according to claim 4, wherein the hydrochloric acid solution has a concentration of 10-18% by mass and the sodium hydroxide solution has a concentration of 15-30% by mass.
6. The sexual lubricant of claim 1, wherein the molar mass ratio of chitosan, L-arginine, 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride and N-hydroxy-succinimide is 1: 1.2-1.5: 0.01-0.05: 0.5-1.
7. The sexual lubricant of claim 1, which is prepared by the following steps:
adding the humifuse euphorbia extract, the aloe extract, the saponin extract and the brucea javanica extract into deionized water, heating to 50-70 ℃, ultrasonically vibrating until the mixture is dissolved, sequentially adding amino acid modified chitosan, 1, 3-butanediol, hydrogenated castor oil polyoxyethylene ether, carbomer, triethanolamine, methylisothiazolinone, iodopropynyl butylcarbamate and propylene glycol, mechanically stirring for 20-40min at 800r/min with 500-dose, transferring to a high-speed shearing dispersion machine, carrying out high-speed shearing dispersion for 20-40min at 2000r/min, finally adding sodium carboxymethylcellulose, carrying out high-speed shearing dispersion for 5-10min at 2500r/min with 2300-dose, sterilizing and subpackaging.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811491650.5A CN111282026A (en) | 2018-12-07 | 2018-12-07 | Sexual lubricant capable of quickly killing various venereal disease pathogens |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201811491650.5A CN111282026A (en) | 2018-12-07 | 2018-12-07 | Sexual lubricant capable of quickly killing various venereal disease pathogens |
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| CN111282026A true CN111282026A (en) | 2020-06-16 |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104800894A (en) * | 2015-04-30 | 2015-07-29 | 重庆市海洁消毒卫生用品有限责任公司 | Formula and preparation method of human lubricant |
| US20170095454A1 (en) * | 2014-07-22 | 2017-04-06 | Professional Compounding Centers Of America | Oral transmucosal compositions including aromatase inhibitors for treating female infertility |
| CN107496439A (en) * | 2016-06-14 | 2017-12-22 | 哈尔滨盈聚生物科技有限公司 | A kind of chitosan derivatives base thimerosal of highly effective and safe and preparation method thereof |
-
2018
- 2018-12-07 CN CN201811491650.5A patent/CN111282026A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20170095454A1 (en) * | 2014-07-22 | 2017-04-06 | Professional Compounding Centers Of America | Oral transmucosal compositions including aromatase inhibitors for treating female infertility |
| CN104800894A (en) * | 2015-04-30 | 2015-07-29 | 重庆市海洁消毒卫生用品有限责任公司 | Formula and preparation method of human lubricant |
| CN107496439A (en) * | 2016-06-14 | 2017-12-22 | 哈尔滨盈聚生物科技有限公司 | A kind of chitosan derivatives base thimerosal of highly effective and safe and preparation method thereof |
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Application publication date: 20200616 |