CN101332317A - Water soluble human lubricant - Google Patents
Water soluble human lubricant Download PDFInfo
- Publication number
- CN101332317A CN101332317A CNA2008101322990A CN200810132299A CN101332317A CN 101332317 A CN101332317 A CN 101332317A CN A2008101322990 A CNA2008101322990 A CN A2008101322990A CN 200810132299 A CN200810132299 A CN 200810132299A CN 101332317 A CN101332317 A CN 101332317A
- Authority
- CN
- China
- Prior art keywords
- water
- human body
- soluble human
- lubricant
- soluble
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention relates to a water-soluble human lubricant which is characterized by comprising the components which are prepared according to parts by weight as follows: 1 to 10 portions of glycerol; 10 to 20 portions of 1, 2-propylene glycol, 0.5 to 1.5 portions of tackifier; 0.1 to 0.2 portion of preservative; 0.5 to 1.5 portions of water-soluble menthol; and 50 to 80 portions of deionized water. The water-soluble human lubricant can be used as the lubricant in sexual life, massage and on a condom, or as the lubricant of an instrument which is used for the diagnosis and examination of a lumen. The lubricant belongs to a water-soluble lubricant with mild and non-tacky property, can be mutually solubilized with the secretion of the female, and is convenient for clean. The water-soluble menthol in the water-soluble human lubricant can stimulate the cold receptor of the skin, thereby leading the human skin or mucosa to have the sense of clear coolness and comfort without the sense of stimulation and comfortlessness and bringing more sentiment for the sexual life.
Description
Technical field
The present invention relates to a kind of lubricant, particularly relate to a kind of water-soluble human body lubricants.
Background technology
Many men and wives in sexual life, for the quality that improves sexual life on the genitals coated lubricant.The women carries out the transition to the old stage from the childbearing age, ovarian function is faded, decrease in estrogen, the human secretory ability goes down thereupon, vagina is dry and astringent gradually, follow the string, particularly the women is after having spent climacteric, because its vagina thins down, gonad secretions is fewer and feweri, reproductive tract are endocrine to be lacked, and makes sexual's penis insert difficulty, has a strong impact on the quality of sexual life, therefore when sexual life, need to use human body lubricants more, to alleviate and to improve the vaginal dryness symptom.
Enter in the process of tract at medical apparatus and instruments (diagnostors such as endoscope, colposcope, cervical clamps, medical catheter), often need coat proper amount of lubricating agent on the surface of medical apparatus and instruments, to reduce the damage of apparatus, also using the light liquid paraffin oil as lubricant at most existing hospital-based outpatient obstetrical clinic, in-patient department to tissue.Liquid paraffin oil is difficult to clean, and tissues such as vagina is had certain zest, and grow mycete easily, is badly in need of wanting a kind of fine soluble oil to be replaced.
In the production process of rubber condoms, generally drip the dimethyl siloxane (being commonly called as silicone oil) of about 0.2～0.35 gram on every condom surface, as interleaving agent, can avoid practising contraception adhesion between jacket layer and the layer, also can play simultaneously the effect of lubricant, can prevent the friction of condom and human epidermal and the damage that does not accommodate epidermis cell that causes.
These above-mentioned lubricants should or not change the character of the material of medical apparatus and instruments and condom in human body untoward reaction being arranged, should not reduce the normal performance of medical apparatus and instruments and condom.
Present widely used human body lubricants is generally the lubricant of oleaginous base, as vaseline and derivant thereof, edible oil, mineral wet goods.Have much and studies show that, the lubricant of many oleaginous bases is with medical apparatus and instruments, when condom contacts, the security performance of the condom that meeting damage natural emulsion is made, medical glove etc., such as mineral oil contact with condom be as short as for 60 seconds after, the intensity decreases of condom is about 90%, so all rubber condoms production commercial cities do not recommend consumer to use mineral oil to make lubricant on the surface of condom.In addition, the intravital normal juice of the lubricant of oleaginous base and women is immiscible fully, in use or use greasy feeling, not easy cleaning are arranged later.
Summary of the invention
The technical problem to be solved in the present invention is intended to overcome the deficiency of above-mentioned prior art, and a kind of water-soluble human body lubricants is provided, and is applicable to the shortage of vagina secretions in the sexual life, effectively alleviates and improve the vaginal dryness symptom, improves life quality; And the lubricant when checking as diagnostor in the tract, the lubricant when also can be used as massage and the lubricant that on condom, uses or the like.This lubricant is inviscid soluble oil of character gentleness, dissolves each other with women's juice, and colorless and odorless is convenient to cleaning.In the process of using water-soluble human body lubricants of the present invention, cold receptor on the water solublity Herba Menthae brain stimulation skin in the water-soluble human body lubricants, make the skin or the mucosa of human body refrigerant comfort sense be arranged and do not have the irriate sense of discomfort, for sexual life brings more susceptible interest.
The water-soluble human body lubricants that the present invention relates to comprises the component of following weight proportion: 1～10 part of glycerol, 1,10～20 parts of 2-propylene glycol, 0.5～1.5 part of viscosifier, 0.1～0.2 part of antiseptic, 0.5～1.5 part in water solublity Herba Menthae brain, 50～80 parts of deionized waters.
The glycerol that comprises in component of the present invention and 1, the 2-propylene glycol can increase viscosity, and excellent moistening effect is also arranged.Glycerol and 1, the lubricant effect of preserving moisture of the mixture of 2-propylene glycol is better than simple glycerol.
Glycerol (glycerol) has another name called glycerol, is the simplest trihydroxy alcohol, molecular formula HOCH
2CH (OH) CH
2OH mainly extensively is formed in the bodies of aminal and plant with the form of glyceride at occurring in nature glycerol, contains a small amount of glycerol in Petiolus Trachycarpi oil and other only a few oils and fatss.Glycerol is a kind of colourless viscous liquid, and odorlessness has warm sweet taste, the energy moisture absorption, relative density 1.2613 (20/4 ℃), water absorption is very strong, can be miscible in alcohol, and dissolve in acetone, trichloroethylene and ether-pure mixed liquor, and can be miscible with water, be insoluble to chloroform, ether, oils.Glycerol is the by-product of soap industry, and also available extraordinary culture propagation molasses make, and can propylene be the raw material synthetic glycerine also.Glycerol as industrial chemicals, is used to make synthetic resin, plastics, paint, nitroglycerin, oils and fats and Cera Flava etc. in a large number, also is used for industry such as pharmacy, spice, cosmetics, hygienic article.
1, the molecular formula of 2-propylene glycol (1,2-Propylene glycol) is HOCH
2CH
2CH
2OH is the stable water absorption liquid of no color or smell thickness, and it is sweet slightly to distinguish the flavor of, have draw moist, inflammable, nontoxic, with water, ethanol and multiple immiscible organic solvent, relative density 1.035～1.037 (25 ℃), surface tension 38mN/m (20 ℃), viscosity 60.5mPas (20 ℃).Many raw materials as resin, plasticizer, surfactant, emulsifying agent and demulsifier also can be used as antifreezing agent and heat carrier.1, the viscosity of 2-propylene glycol and good hygroscopicity, and nontoxic, thereby in food, medicine and cosmetics industry, be widely used as hygroscopic agent, antifreeze, lubricant and solvent, be fit to the use of human body low dose, slight sensitization.
In component of the present invention, also comprise hydroxyethyl-cellulose (HEC) as viscosifier.Hydroxyethyl-cellulose is a kind of white or little yellow, does not have and smell tasteless, runny powder that apparent density is 0.35～0.61g/mL; Softening temperature is 135～140 ℃; Decomposition temperature is 205～210 ℃; Burning velocity is slower; PH value viscosity in 2～12 scopes changes less, but surpasses this scope viscosity degradation.HEC is as a kind of non-ionic water-soluble polymer, except that having thickening, suspension, bonding, floatingization, film forming, dispersion, water conservation and providing the protective colloid action, also has following character:
(1) HEC dissolves in hot water or cold water, and dissolution velocity raises with temperature and speed, and high temperature or boil does not precipitate, and is insoluble in most of organic solvents generally speaking, makes it have large-scale dissolubility and viscosity characteristics, and non-hot gelation;
(2) nonionic own can coexist with other water-soluble polymers, surfactant, the salt on a large scale, is a kind of good colloid thickening agent that contains the high concentration electrolyte solution;
(3) water holding capacity exceeds one times than methylcellulose, has flow adjustment preferably;
(4) to compare dispersibility the poorest for the dispersibility of HEC and methylcellulose of generally acknowledging and hydroxypropyl emthylcellulose, but the protecting colloid ability is the strongest.
Carbomer as viscosifier is a kind of moist very strong white bulky powder that draws.Because have a large amount of hydroxy-acid groups in the molecule, this product and polyacrylic acid have closely similar physicochemical property, faint cross-bond makes it to have the suction phenomenon similar to cross-linked sodium polyacrylate again in the structure simultaneously.Carbomer rapid swelling in water, but do not dissolve, when with in the alkali and the time, carbomer is dissolving gradually in water, pure and mild glycerol, forms clear and bright solution when low concentration, concentration forms translucent gels when big, gel has certain intensity and elasticity.Hydroxy-acid group makes its aqueous dispersions be acid, and the pH value of 1% aqueous dispersions is about 3.11, and viscosity is lower.When with in the alkali and the time, along with macromole dissolves gradually, viscosity also increases, in pH 6～11 o'clock viscosity and denseness maximum.Carbomer is a kind of novel medicinal high polymer adjuvant, has been widely used in preparation, can prepare hydrogel adhesive, can make suspending agent, coemulsifier etc.Carbomer is to be produced by U.S. Goodrich chemical company the earliest, and ProductName Carbopol has the specification kind of different molecular weights such as Carbopol 940, Carbopol 934, Carbopol 941.The similar kind of domestic existing pharmaceutical grade and cosmetics-stage is divided into 3 grades by the viscosity size, i.e. high viscosity, medium viscosity, low viscosity, and molecular weight is 4 * 10
6, 3 * 10
6, 1 * 10
6, corresponding with above-mentioned external carbomer specification respectively.Acritamer 940 is fit to do the hydrophilic gel substrate of ointment, cream, has the characteristics of water-soluble base, and putting on the skin has special fine and smooth smooth feeling on skin, and is splendid with the skin coupling effect; Carbomer 934 is fit to do suspending agent or coemulsifier; Carbopol 941 then is used for the tackify of for oral administration or liquid preparation for external use, also is current unique pharmaceutical grade adjuvant of taking in being considered to do.
Also comprise antiseptic in component of the present invention, antiseptic can have the effect of killing preferably and suppressing to anaerobe, is beneficial to the preservation of lubricant.
Nipagin ester is a p-Hydroxybenzoate, is the antiseptic safely and effectively that adopts in the world, is widely used in industries such as food, cosmetics and medicine.Nipagin ester is colourless tiny crystallization or crystalline powder, and astringent taste is arranged slightly, and almost odorless is stable to photo-thermal, is slightly soluble in water, is soluble in ethanol.Nipagin ester is compared with traditional benzoic acid, sorbic acid antiseptic, and its antiseptic effect is difficult for changing with the variation of pH, and simultaneously, they also have low toxicity, efficient, characteristics such as consumption is few, antimicrobial spectrum is wide.Nipagin ester series as antiseptic has: methyl hydroxybenzoate, ethyl hydroxybenzoate, propylparaben, and they are to food, and cosmetics all have good preventing and ferment, suppress bacterial multiplication and sterilizing ability.Because parabens all is insoluble in water, so normally they are dissolved in sodium hydroxide earlier, acetic acid in the ethanol, uses then.Be better performance antisepsis, preferably two kinds of nipalgins or two or more parabenses mixed use.Nipalgin has broad-spectrum bactericidal action, and to Gram-positive, negative bacterium, yeast and mycete have very strong killing action; Nipalgin is chemically belonging to inert substance, easy and all cpds compatibility.
Chlorhexidine gluconate is all very low safe disinfection agent of a kind of toxicity, corrosivity and zest, to skin, mucosa nonirritant, is widely used in the sterilization of skin mucosa, wound surface and urinary organs, and its sterilization and bacteriostasis are good, and stable in properties is easy to use.
Two imidazolidinyl urea (Diazolidinyl Urea), molecular formula: C
8H
14N
4O
7, the mobile easily moisture absorption powder (moisture absorption does not influence bacteriostatic activity) of off-white color, little band formaldehyde odor, very easily water-soluble, easy deliquescence, dissolubility is very low in oil, to the skin avirulence, there is not allergy, nonirritant, good water solubility, compatibility good (not can by other raw material passivation), its antiseptic action principle is a slow release formaldehyde, to removing from office blue formula positive bacteria, the blue formula negative bacterium of leather, comprise that pseudomonas has fungistatic effect, share good antibiotic potentiation with Nipagin ester (benzoates).
In component of the present invention, also comprise water solublity Herba Menthae oil.This natural refining mint oils adopts efficient solubilising, controlled release, slow release etc. the principle nuclear technology is composite and forms, and skin, mucosa, olfactory sensation, the sense of taste etc. are had pure and fresh, refrigerant, antipruritic, firming effect, gives the refrigerant comfort sense of cold-peace and does not have the irriate sense of discomfort.The refrigerant time is long, can refreshment, alleviate tired, bactericidal antiphlogistic, dispel the effects such as sufferings after biting, be specially adapted to water base oral-cavity article such as spring, summer, autumn, articles for washing, cosmetics for skin, medicine, food, beverage etc.
In water-soluble human body lubricants of the present invention, also added the pH value regulator, the pH value of water-soluble human body lubricants has been adjusted to 6～7.
Water-soluble human body lubricants of the present invention has following good effect: 1. as lubricated main body, its lubricity obviously improves than the lubricant of oleaginous bases such as silicone oil water-soluble human body lubricants of the present invention with water-soluble material; 2. soluble oil of the present invention all adopts water-soluble material formulated, mixes with the normal juice of female body, does not have oily sensation, is easy to clean, and sensuously is easier to accept, and human body is had no adverse reaction; 3. can not change the character of the material of medical apparatus and instruments and condom, reduce the fracture phenomena that takes place in the use of condom; 4. can not reduce the normal performance of medical apparatus and instruments and condom; 5. in the process of using water-soluble human body lubricants of the present invention, cold receptor on the water solublity Herba Menthae brain stimulation skin in the water-soluble human body lubricants, make the skin or the mucosa of human body refrigerant comfort sense be arranged and do not have the irriate sense of discomfort, for sexual life brings more susceptible interest.
The specific embodiment
The component and the weight proportion thereof of specific embodiments 1～6 of the present invention see the following form:
| Embodiment | 1 | 2 | 3 | 4 | 5 | 6 |
| Glycerol (part) | 1 | 3 | 3 | 5 | 8 | 10 |
| Water solublity Herba Menthae brain (part) | 1.5 | 0.5 | 0.5 | 0.7 | 0.7 | 1.5 |
| Hydroxyethyl-cellulose (part) | 1.5 | 1.0 | 1.1 | 0.2 | - | 0.5 |
| Carbomer (part) | - | 0.5 | 0.1 | 0.3 | 0.8 | 0.9 |
| Methyl hydroxybenzoate (part) | 0.12 | 0.05 | 0.02 | - | 0.09 | 0.02 |
| Ethyl hydroxybenzoate (part) | 0.08 | 0.01 | 0.07 | 0.05 | 0.04 | 0.09 |
| Propylparaben (part) | - | 0.08 | 0.01 | - | 0.05 | - |
| Chlorhexidine gluconate (part) | - | - | 0.05 | - | - | 0.06 |
| Two imidazolidinyl urea (part) | - | - | - | 0.05 | - | 0.02 |
| 1,2-propylene glycol (part) | 20 | 10 | 15 | 15 | 15 | 20 |
| Deionized water (part) | 53.80 | 54.86 | 64.15 | 79.63 | 75.62 | 57.91 |
In above-mentioned embodiment, used glycerol, 1,2-propylene glycol, hydroxyethyl-cellulose are medical grade, and used deionized water is a redistilled water.
In embodiment 1～6,1, the existing moisture-keeping function of 2-propylene glycol is again a kind of penetrating agent, can increase simultaneously the dissolving of methyl hydroxybenzoate as antiseptic, ethyl hydroxybenzoate, propylparaben, chlorhexidine gluconate, two imidazolidinyl urea.
In embodiments of the invention 1～6, also added the pH value regulator, the pH value of water-soluble human body lubricants is adjusted to 6～7.The pH value regulator that uses in the embodiment 1～3 is acetic acid, and the pH value regulator that uses in the embodiment 4～6 is citric acid.PH value regulator used in the present invention can also be the pH value regulator that pH value can be adjusted to other kinds of 6～7.
The preparation method of above-mentioned specific embodiments of the present invention is:
Water solublity Herba Menthae brain is dissolved in the deionized water, after making it to become clear solution, add hydroxyethyl-cellulose under the stirring at low speed, it is drenched fully to be stirred to all hydroxyethyl-celluloses, treat that hydroxyethyl-cellulose dissolves fully after, add glycerol (containing antiseptic) and 1 successively, the 2-propylene glycol, continue to stir, adding pH value regulator is adjusted to 6～7 with the pH value of mixed liquor, can obtain water-soluble human body lubricants of the present invention.
When water-soluble human body lubricants of the present invention is used for human body skin or mucosa, contain the cold receptor on the water solublity Herba Menthae brain stimulation skin in the water-soluble human body lubricants, give the refrigerant comfort sense of cold-peace and do not have the irriate sense of discomfort, but can not cause actual temperature change and slight local anesthetic action.
Water-soluble human body lubricants to embodiment of the present invention 1～6 is estimated, nasil, determines it is the water white transparency thick liquid, does not have precipitation; Have mint flavored, no foreign body.
The physical and chemical inspection index is: viscosity (25 ℃) mPas 1500-2000
Relative density g/mL＞1.0
Acidity-basicity ph 6.0-7.0
Skin and mucosa there are not bad stimulation and anaphylaxis.
Claims (8)
1, a kind of water-soluble human body lubricants, it is characterized in that described water-soluble human body lubricants comprises the component of following weight proportion: 1～10 part of glycerol, 1,10～20 parts of 2-propylene glycol, 0.5～1.5 part of viscosifier, 0.1～0.2 part of antiseptic, 0.5～1.5 part in water solublity Herba Menthae brain, 50～80 parts of deionized waters.
2, water-soluble human body lubricants as claimed in claim 1 is characterized in that: described water-soluble human body lubricants comprises that also the pH value that is used for lubricant is adjusted to 6～7 pH value regulator.
3, water-soluble human body lubricants as claimed in claim 2 is characterized in that: the pH value regulator is acetic acid or citric acid.
4. as any described water-soluble human body lubricants in the claim 1 to 3, it is characterized in that: described viscosifier are a kind of or its combination in hydroxyethyl-cellulose, the carbomer 934.
5, as any described water-soluble human body lubricants in the claim 1 to 3, it is characterized in that: described antiseptic is a kind of or its combination in methyl hydroxybenzoate, the ethyl hydroxybenzoate.
6, as any described water-soluble human body lubricants in the claim 1 to 3, it is characterized in that: described antiseptic is any one or a few the combination in methyl hydroxybenzoate, ethyl hydroxybenzoate, the propylparaben.
7. as any described water-soluble human body lubricants in the claim 1 to 3, it is characterized in that: described antiseptic is any one or a few the combination in methyl hydroxybenzoate, ethyl hydroxybenzoate, propylparaben, the chlorhexidine gluconate.
8. as any described water-soluble human body lubricants in the claim 1 to 3, it is characterized in that: described antiseptic is any one or several combination in methyl hydroxybenzoate, ethyl hydroxybenzoate, propylparaben, chlorhexidine gluconate, the two imidazolidinyl urea.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008101322990A CN101332317A (en) | 2008-07-24 | 2008-07-24 | Water soluble human lubricant |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008101322990A CN101332317A (en) | 2008-07-24 | 2008-07-24 | Water soluble human lubricant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101332317A true CN101332317A (en) | 2008-12-31 |
Family
ID=40195366
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2008101322990A Pending CN101332317A (en) | 2008-07-24 | 2008-07-24 | Water soluble human lubricant |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101332317A (en) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102989045A (en) * | 2012-11-12 | 2013-03-27 | 梁忠品 | Biocompatible water-soluble composition and use thereof |
| CN103203042A (en) * | 2013-04-13 | 2013-07-17 | 江苏健裕健康医疗器械有限公司 | Water-soluble medical lubricant |
| CN103405591A (en) * | 2013-05-30 | 2013-11-27 | 闫一粼 | Nourishing type water-soluble personal lubricant and preparation method thereof, and condom |
| CN103785068A (en) * | 2014-02-19 | 2014-05-14 | 江苏苏云医疗器材有限公司 | Water soluble lubricant and preparation method thereof |
| CN106137514A (en) * | 2016-07-26 | 2016-11-23 | 广东诺丝科技股份有限公司 | A kind of novel decorative pattern condom of tatooing |
| CN106176023A (en) * | 2016-07-26 | 2016-12-07 | 广东诺丝科技股份有限公司 | A kind of ice fire dress condom of novel interior ice exterior-heat |
| CN106178141A (en) * | 2016-08-17 | 2016-12-07 | 贵州金玖生物技术有限公司 | Water soluble medical lubricating jelly and preparation method thereof |
| CN107998461A (en) * | 2017-11-17 | 2018-05-08 | 深圳市宜丽健康科技发展有限公司 | A kind of sheath that is exclusively used in has the function of the soluble oil of composite antibacterial |
| EP3616687A4 (en) * | 2017-04-27 | 2020-12-30 | Lovtsov, Valentin Vyacheslavovich | Preparation for the treatment and/or prophylaxis of inflammatory infectious diseases |
-
2008
- 2008-07-24 CN CNA2008101322990A patent/CN101332317A/en active Pending
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102989045A (en) * | 2012-11-12 | 2013-03-27 | 梁忠品 | Biocompatible water-soluble composition and use thereof |
| CN102989045B (en) * | 2012-11-12 | 2015-02-25 | 广州共禾医药科技有限公司 | Biocompatible water-soluble composition and use thereof |
| CN103203042A (en) * | 2013-04-13 | 2013-07-17 | 江苏健裕健康医疗器械有限公司 | Water-soluble medical lubricant |
| CN103405591A (en) * | 2013-05-30 | 2013-11-27 | 闫一粼 | Nourishing type water-soluble personal lubricant and preparation method thereof, and condom |
| CN103785068A (en) * | 2014-02-19 | 2014-05-14 | 江苏苏云医疗器材有限公司 | Water soluble lubricant and preparation method thereof |
| CN106137514A (en) * | 2016-07-26 | 2016-11-23 | 广东诺丝科技股份有限公司 | A kind of novel decorative pattern condom of tatooing |
| CN106176023A (en) * | 2016-07-26 | 2016-12-07 | 广东诺丝科技股份有限公司 | A kind of ice fire dress condom of novel interior ice exterior-heat |
| CN106178141A (en) * | 2016-08-17 | 2016-12-07 | 贵州金玖生物技术有限公司 | Water soluble medical lubricating jelly and preparation method thereof |
| EP3616687A4 (en) * | 2017-04-27 | 2020-12-30 | Lovtsov, Valentin Vyacheslavovich | Preparation for the treatment and/or prophylaxis of inflammatory infectious diseases |
| CN107998461A (en) * | 2017-11-17 | 2018-05-08 | 深圳市宜丽健康科技发展有限公司 | A kind of sheath that is exclusively used in has the function of the soluble oil of composite antibacterial |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101327346A (en) | Water-soluble human body lubricants | |
| CN101332317A (en) | Water soluble human lubricant | |
| CN103405592A (en) | Bacteriostatic water-soluble personal lubricant and preparation method thereof, and condom | |
| CN101703814A (en) | Lubricating agent for use in coelom introduction by medicinal appliance | |
| CN103083733A (en) | Medical water-based lubricant for introducing instrument into body cavity | |
| EP3074023B1 (en) | Pharmaceutical compositions with hydrating and lubricating activity | |
| CN102512338A (en) | Water-soluble human body lubricant and preparation method thereof | |
| CN103405610A (en) | Compact-type water-soluble human lubricant, preparation method of lubricant and condom | |
| CN107961399A (en) | A kind of water-based body lotion containing complex antimicrobials | |
| CN103405591A (en) | Nourishing type water-soluble personal lubricant and preparation method thereof, and condom | |
| CN1225291C (en) | Water-soluble human body lubricant | |
| CN104800894A (en) | Formula and preparation method of human lubricant | |
| CN103405593A (en) | Water soluble human lubricant capable of enhancing libido and preparation method thereof as well as condom | |
| JP5815546B2 (en) | Lubricating aqueous composition | |
| CN103405594A (en) | Water-soluble personal lubricant, preparation method thereof, and condom employing lubricant | |
| CN100592915C (en) | Ecological vagina cleaning bacteriostasis liquid | |
| CN109453438A (en) | A kind of preparation method of antibacterial anti-inflammatory sheath | |
| CN100490906C (en) | Absorbent article containing a skin-care agent | |
| CN105963367A (en) | Preoperative nursing gel for anorectal surgery and preparation method of gel | |
| GB2603117A (en) | Lubricant | |
| CN106730042A (en) | A kind of preparation method of low-residual hyaluronic acid matrix human body lubricants | |
| CN104941010B (en) | A kind of Medical vagina lubricating fluid and preparation method thereof | |
| ES2334746A1 (en) | Product for intimate hygiene based on red mirtillo and procedure for its preparation (Machine-translation by Google Translate, not legally binding) | |
| EP4277600A1 (en) | Lubricant | |
| JPS6377814A (en) | Lubricating agent |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Open date: 20081231 |