CN105535170A - Compound male private part nursing lotion and preparation method thereof - Google Patents
Compound male private part nursing lotion and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
Abstract
The invention discloses compound male private part nursing lotion and a preparation method thereof. The lotion is mainly prepared from 1.3-2.8% of storax, 1.0-2.4% of terpilenol, 0.8-1.6% of taxifolin, 0.6-1.5% of sesquiterpene, 0.5-1.3% of cianidanol, 0.5-1.2% of eburicoic acid, 0.6-1.8% of water-soluble vitamin E, 0.4-0.8% of hyaluronic acid, 2.6-5.6% of olive oil, 0.6-1.4% of rose hydrolat, 0.3-0.5% of triclosan, 0.8-2.4% of succinate, 5.0-8.0% of ethyl alcohol and the balance distilled water. The lotion further comprises auxiliaries including 1.0-4.2% of a pH value regulating agent, 1.5-2.3% of surfactant, 1.2-1.8% of an anti-corrosion agent and 0.9-1.3% of a stabilizing agent. The lotion has good antibacterial and anti-inflammation functions, has the functions of clearing away heat, eliminating dampness and relieving itching, can effectively promote absorption of the medicine effective components by skin, can accelerate cell metabolism, improves skin, deeply cleans away dirt and bacteria hidden in hair follicles, and is not irritant to the skin of private parts of males, is mild in medicine effect, little in irritation, free of adverse effects and good in clinical effect.
Description
Technical field
The present invention relates to surgical nursing medication field, specifically relate to a kind of compound recipe male privates nursing lotion and preparation method thereof.
Background technology
As everyone knows, women due to vaginal secretions many, cleaning the lower part of the body be requisite thing every day, form a habit, and male seldom have cleaning the lower part of the body custom.But for male, scrotum, skin of penis fold are many, sweat gland is many, secretions is also many, ventilate when especially wearing chemical fibre underwear not smooth, so the seminal fluid that a large amount of perspiration, the urine of residual flow, the feces slag do not cleaned, man and wife stay after having sexual intercourse and female secretion liquid etc., all can pollute whole penis, scrotum and perineal region.The breeding of this environment to microorganisms such as antibacterials is highly beneficial, if do not cleaned up, not only can frowziness, and be also unfavorable for the health care of skin.Especially middle-aged and elderly people is due to thinning of skin, and resistance declines, and do not note cleaning the lower part of the body, not only perineal position, and both sides thigh also may occur rotten to the corn phenomenon.In addition, during sexual intercourse, these filths and microorganism easily enter vagina, affect the cleannes of vagina, harm women's health.So, by the good custom of the warm water cleaning lower part of the body before male also should form and sleep.This part thing of the cleaning lower part of the body shouldn't be looked down upon, more do not become a mere formality, otherwise likely get half the result with twice the effort, even run counter to desire, clean and not easily cause inflammation, especially redundant prepuce person, often will remove smegma, otherwise not only oneself is harmful to, even likely gives others these filths and microorganisms spreading.Some male thinks that clean number of times is more, is more conducive to health, and this is also the idea of mistake in fact, and the clean system of defense excessively easily destroying himself, makes antibacterial more easily enter in body.
The cleaning-nursing of man's privates, and not only refer to simple cleaning, first be to notice that the water temperature of cleaning is suitable, but clear water can only remove the dirt on shallow top layer, therefore need to use some conditioning liquids deeply to clean the antibacterial in hair follicle and the secretions inside skin-fold, so select suitable conditioning liquid to be vital, can not only clean, the eliminating bacteria of deep layer.Opposing is irritated, and harmless to the skin of privates, maintenance comfort that can be permanent.
Summary of the invention
The technical problem that the present invention solves is to provide a kind of compound recipe male privates nursing lotion and preparation method thereof.
For solving the problems of the technologies described above, the technical solution adopted in the present invention is as follows:
A kind of compound recipe male privates nursing lotion, its main component consists of: Styrax 1.3 ~ 2.8%, terpineol 1.0 ~ 2.4%, Taxifolin 0.8 ~ 1.6%, sesquiterpene 0.6 ~ 1.5%, cachou extract 0.5 ~ 1.3%, eburicoic acid 0.5 ~ 1.2%, watermiscible vitamin E 0.6 ~ 1.8%, hyaluronic acid 0.4 ~ 0.8%, olive oil 2.6 ~ 5.6%, MEIGUI CHUNLU 0.6 ~ 1.4%, triclosan 0.3 ~ 0.5%, succinic acid 0.8 ~ 2.4%, ethanol 5.0 ~ 8.0%, surplus is distilled water, described lotion also comprises adjuvant: pH value regulator 1.0 ~ 4.2%, surfactant 1.5 ~ 2.3%, antiseptic 1.2 ~ 1.8%, stabilizing agent 0.9 ~ 1.3%.
Further, described ethanol is mass concentration is 55 ~ 65%.
Further, described pH value regulator is: lactic acid and sodium bicarbonate, citric acid and sodium dihydrogen phosphate wherein one or several, described compound recipe male privates nursing lotion pH value is 6.0 ~ 7.0, human body is overall weakly alkaline, the secretions of privates and antibacterial be mostly aobvious alkalescence also, therefore weakly acidic washing liquid can neutralize weakly alkaline secretions, to privates skin without any stimulation.
Further, described surfactant is: cocos nucifera oil both sexes sodium acetate, lauryl amidopropyl amine oxide, 1-isobutyl-3,5-dimethylhexylphosphoric acid potassium, alkyl polyglucoside class wherein one or several, soluble in water and polar organic solvent, aqueous solution is in acid condition in cationic, there is good thickening, antistatic, softness, foam enhancing, steady bubble and detergency ability, zest is low, effectively can reduce the zest of the anion surfactant in detergent, can significantly improve cleaning capacity.
Further, described antiseptic is: sodium benzoate, hibitane, ethyl hydroxybenzoate, phenoxyethanol wherein one or several, have well antibacterial and antiseptic effect under weakly acidic environment.
Further, described stabilizing agent is: hydroxyethyl-cellulose, D-trehalose, xanthan gum, sorbitol, ethylenediaminetetraacetic acid wherein one or several, this type of stabilizing agent can impel compounding substances to slow down reaction in weak acid environment, keep chemical equilibrium, reduce surface tension, prevent the effects such as light, thermal decomposition or oxidation Decomposition.
A kind of preparation method of compound recipe male privates nursing lotion is:
Step one: by Styrax and the olive oil weight ratio mix homogeneously obtained mixing grease according to 1:2, for subsequent use, after Styrax and mixed with olive oil, external can amelioration of inflammation, elimination eczema and pruritus;
Step 2: make it fully dissolve according to the weight ratio mixing post-heating of 1:5 ~ 20 to stirring after 95 ~ 100 DEG C cachou extract and distilled water, aggregate into unformed tannin, secretion can be reduced and protect from infection, to be cooledly to room temperature, add obtained mixed liquor after terpineol, Taxifolin, sesquiterpene, eburicoic acid %, watermiscible vitamin E, hyaluronic acid, MEIGUI CHUNLU, triclosan, succinic acid, ethanol respectively, leave standstill 8 ~ 12h, for subsequent use;
Step 3: mixed liquor prepared by mixing grease step one prepared and step 2 is uniformly mixed under mechanical action, add surfactant, antiseptic, stabilizing agent simultaneously, after making it fully dissolve, add pH value regulator adjust ph, and then to be placed in homogenizer after homogenizing process 15 ~ 30min, be the ultrafiltration post ultrafiltration of 6000 ~ 8000 again through the molecular weight that dams, obtain ultrafiltrate, seal up for safekeeping after packaging and namely obtain described compound recipe male privates nursing lotion.
The invention has the beneficial effects as follows: the present invention has good anti-inflammation, heat clearing and damp drying, antipruritic effect, effective promotion skin is to the absorption of effective ingredient, and can cellular metabolism be accelerated, improve skin quality, the dirt be hidden in hair follicle and antibacterial are deeply cleaned, the skin quality for male's privates is non-stimulated, drug effect is gentle, little to wound zest, without any untoward reaction, there is good clinical effectiveness.
Detailed description of the invention
Embodiment 1:
A kind of compound recipe male privates nursing lotion, its main component consists of: Styrax 1.3%, terpineol 1.0%, Taxifolin 0.8%, sesquiterpene 0.6%, cachou extract 0.5%, eburicoic acid 0.5%, watermiscible vitamin E 0.6%, hyaluronic acid 0.4%, olive oil 2.6%, MEIGUI CHUNLU 0.6%, triclosan 0.3%, succinic acid 0.8%, ethanol 5.0%, surplus are distilled water, and described lotion also comprises adjuvant: pH value regulator 1.0%, surfactant 1.5%, antiseptic 1.2%, stabilizing agent 0.9%.
Wherein, described ethanol is mass concentration is 55%.Described pH value regulator is lactic acid and sodium bicarbonate, described compound recipe male privates nursing lotion pH value is 6.0, human body is overall weakly alkaline, the secretions of privates and antibacterial be mostly aobvious alkalescence also, therefore weakly acidic washing liquid can neutralize weakly alkaline secretions, to privates skin without any stimulation.Described surfactant is cocos nucifera oil both sexes sodium acetates, soluble in water and polar organic solvent, aqueous solution is in acid condition in cationic, there is good thickening, antistatic, softness, foam enhancing, steady bubble and detergency ability, zest is low, effectively can reduce the zest of the anion surfactant in detergent, can cleaning capacity be significantly improved.Described antiseptic is sodium benzoate, has well antibacterial and antiseptic effect under weakly acidic environment.Described stabilizing agent is hydroxyethyl-cellulose, and this stabilizing agent can impel compounding substances to slow down reaction in weak acid environment, keeps chemical equilibrium, reduces surface tension, prevents the effects such as light, thermal decomposition or oxidation Decomposition.
A kind of preparation method of compound recipe male privates nursing lotion is:
Step one: by Styrax and the olive oil weight ratio mix homogeneously obtained mixing grease according to 1:2, for subsequent use, after Styrax and mixed with olive oil, external can amelioration of inflammation, elimination eczema and pruritus;
Step 2: make it fully dissolve according to the weight ratio mixing post-heating of 1:5 to stirring after 95 DEG C cachou extract and distilled water, aggregate into unformed tannin, secretion can be reduced and protect from infection, to be cooledly to room temperature, add obtained mixed liquor after terpineol, Taxifolin, sesquiterpene, eburicoic acid %, watermiscible vitamin E, hyaluronic acid, MEIGUI CHUNLU, triclosan, succinic acid, ethanol respectively, leave standstill 8h, for subsequent use;
Step 3: mixed liquor prepared by mixing grease step one prepared and step 2 is uniformly mixed under mechanical action, add surfactant, antiseptic, stabilizing agent simultaneously, after making it fully dissolve, add pH value regulator adjust ph, and then to be placed in homogenizer after homogenizing process 15min, be the ultrafiltration post ultrafiltration of 6000 again through the molecular weight that dams, obtain ultrafiltrate, seal up for safekeeping after packaging and namely obtain described compound recipe male privates nursing lotion.
Embodiment 2:
A kind of compound recipe male privates nursing lotion, its main component consists of: Styrax 2.05%, terpineol 1.7%, Taxifolin 1.2%, sesquiterpene 1.05%, cachou extract 0.9%, eburicoic acid 0.85%, watermiscible vitamin E 1.2%, hyaluronic acid 0.6%, olive oil 4.1%, MEIGUI CHUNLU 1.0%, triclosan 0.4%, succinic acid 1.6%, ethanol 6.5%, surplus are distilled water, and described lotion also comprises adjuvant: pH value regulator 2.6%, surfactant 1.9%, antiseptic 1.5%, stabilizing agent 1.1%.
Wherein, described ethanol is mass concentration is 60%.Described pH value regulator is lactic acid and sodium bicarbonate, described compound recipe male privates nursing lotion pH value is 6.5, human body is overall weakly alkaline, the secretions of privates and antibacterial be mostly aobvious alkalescence also, therefore weakly acidic washing liquid can neutralize weakly alkaline secretions, to privates skin without any stimulation.Described surfactant is lauryl amidopropyl amine oxide, soluble in water and polar organic solvent, aqueous solution is in acid condition in cationic, there is good thickening, antistatic, softness, foam enhancing, steady bubble and detergency ability, zest is low, effectively can reduce the zest of the anion surfactant in detergent, can cleaning capacity be significantly improved.Described antiseptic is hibitane, has well antibacterial and antiseptic effect under weakly acidic environment.Described stabilizing agent is D-trehalose, and this stabilizing agent can impel compounding substances to slow down reaction in weak acid environment, keeps chemical equilibrium, reduces surface tension, prevents the effects such as light, thermal decomposition or oxidation Decomposition.
A kind of preparation method of compound recipe male privates nursing lotion is:
Step one: by Styrax and the olive oil weight ratio mix homogeneously obtained mixing grease according to 1:2, for subsequent use, after Styrax and mixed with olive oil, external can amelioration of inflammation, elimination eczema and pruritus;
Step 2: make it fully dissolve according to the weight ratio mixing post-heating of 1:12.5 to stirring after 97.5 DEG C cachou extract and distilled water, aggregate into unformed tannin, secretion can be reduced and protect from infection, to be cooledly to room temperature, add obtained mixed liquor after terpineol, Taxifolin, sesquiterpene, eburicoic acid %, watermiscible vitamin E, hyaluronic acid, MEIGUI CHUNLU, triclosan, succinic acid, ethanol respectively, leave standstill 10h, for subsequent use;
Step 3: mixed liquor prepared by mixing grease step one prepared and step 2 is uniformly mixed under mechanical action, add surfactant, antiseptic, stabilizing agent simultaneously, after making it fully dissolve, add pH value regulator adjust ph, and then to be placed in homogenizer after homogenizing process 22.5min, be the ultrafiltration post ultrafiltration of 7000 again through the molecular weight that dams, obtain ultrafiltrate, seal up for safekeeping after packaging and namely obtain described compound recipe male privates nursing lotion.
Embodiment 3:
A kind of compound recipe male privates nursing lotion, its main component consists of: Styrax 2.8%, terpineol 2.4%, Taxifolin 1.6%, sesquiterpene 1.5%, cachou extract 1.3%, eburicoic acid 1.2%, watermiscible vitamin E 1.8%, hyaluronic acid 0.8%, olive oil 5.6%, MEIGUI CHUNLU 1.4%, triclosan 0.5%, succinic acid 2.4%, ethanol 8.0%, surplus are distilled water, and described lotion also comprises adjuvant: pH value regulator 4.2%, surfactant 2.3%, antiseptic 1.8%, stabilizing agent 1.3%.
Wherein, described ethanol is mass concentration is 65%.Described pH value regulator is citric acid and sodium dihydrogen phosphate, described compound recipe male privates nursing lotion pH value is 7.0, human body is overall weakly alkaline, the secretions of privates and antibacterial be mostly aobvious alkalescence also, therefore weakly acidic washing liquid can neutralize weakly alkaline secretions, to privates skin without any stimulation.Described surfactant is 1-isobutyl-3,5-dimethylhexylphosphoric acid potassium, soluble in water and polar organic solvent, aqueous solution is in acid condition in cationic, there is good thickening, antistatic, softness, foam enhancing, steady bubble and detergency ability, zest is low, effectively can reduce the zest of the anion surfactant in detergent, can cleaning capacity be significantly improved.Described antiseptic is ethyl hydroxybenzoate, has well antibacterial and antiseptic effect under weakly acidic environment.Described stabilizing agent is xanthan gum, and this type of stabilizing agent can impel compounding substances to slow down reaction in weak acid environment, keeps chemical equilibrium, reduces surface tension, prevents the effects such as light, thermal decomposition or oxidation Decomposition.
A kind of preparation method of compound recipe male privates nursing lotion is:
Step one: by Styrax and the olive oil weight ratio mix homogeneously obtained mixing grease according to 1:2, for subsequent use, after Styrax and mixed with olive oil, external can amelioration of inflammation, elimination eczema and pruritus;
Step 2: make it fully dissolve according to the weight ratio mixing post-heating of 1:20 to stirring after 100 DEG C cachou extract and distilled water, aggregate into unformed tannin, secretion can be reduced and protect from infection, to be cooledly to room temperature, add obtained mixed liquor after terpineol, Taxifolin, sesquiterpene, eburicoic acid %, watermiscible vitamin E, hyaluronic acid, MEIGUI CHUNLU, triclosan, succinic acid, ethanol respectively, leave standstill 12h, for subsequent use;
Step 3: mixed liquor prepared by mixing grease step one prepared and step 2 is uniformly mixed under mechanical action, add surfactant, antiseptic, stabilizing agent simultaneously, after making it fully dissolve, add pH value regulator adjust ph, and then to be placed in homogenizer after homogenizing process 30min, be the ultrafiltration post ultrafiltration of 8000 again through the molecular weight that dams, obtain ultrafiltrate, seal up for safekeeping after packaging and namely obtain described compound recipe male privates nursing lotion.
Animal toxicity is tested:
Test material: choose experiment male rat 30, every vital sign is normal, body weight 150-200g.
Test method: just the hair of male rat surrounding genital is rejected, expose the skin of 2cm*2cm size, to the nursing lotion that all male rats use the present invention to prepare, every day smears twice, without thin up, original content is smeared, and uses 30 days continuously, observe the change that rat smears area skin, this consumption is 500 times of positive usual amounts.
Result of the test: on inspection, it is without exception that all male rats smear area skin, and every vital sign is without exception.
Clinical trial:
1. Case retrieval dividing into groups: inventor collects 120 routine male altogether, is divided into four groups at random, often organizes 30 people, three groups of data such as sex, age there are no significant difference, has comparability.
2. test method: give each group of patient lotion that uses embodiment 1, embodiment 2, embodiment 3 prepares respectively, by lotion and warm water according to the volume ratio mix homogeneously of 1:1000, clean 1 every day, matched group uses warm water to clean, and cleans 1 every day.
3. criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
(1) fully recover: privates skin quality is clean and tidy, free from extraneous odour, comfort strengthens;
(2) effective: privates skin quality makes moderate progress, there is obvious comfort comparatively;
(3) invalid: privates skin quality is without alleviation or increase the weight of.
3.2 treatment statistical results
Table 1-tetra-group comparitive study
| The medicine taken | Case number | Recovery from illness | Effective | Invalid | Untoward reaction | Total effective rate % |
| Embodiment 1 | 30 | 15 | 13 | 2 | 0 | 93.3 |
| Embodiment 2 | 30 | 24 | 15 | 1 | 0 | 96.7 |
| Embodiment 3 | 30 | 18 | 9 | 3 | 0 | 90.0 |
| Matched group | 30 | 12 | 9 | 9 | 0 | 70.0 |
4. conclusion: in clinical trial process, use compound recipe male privates of the present invention to nurse lotion and find no any untoward reaction, as seen from the data in Table 1, nursing lotion total effective rate of the present invention reaches more than 90.0%, has fine nursing efficacy.
Last it is noted that above embodiment is only in order to illustrate technical scheme of the present invention, be not intended to limit; Although with reference to previous embodiment to invention has been detailed description, those of ordinary skill in the art is to be understood that: it still can be modified to the technical scheme described in previous embodiment, or carries out equivalent replacement to wherein portion of techniques feature; And these amendments or replacement, do not make the essence of appropriate technical solution depart from the spirit and scope of embodiment of the present invention technical scheme.
Claims (8)
1. a compound recipe male privates nursing lotion, it is characterized in that, its main component consists of: Styrax 1.3 ~ 2.8%, terpineol 1.0 ~ 2.4%, Taxifolin 0.8 ~ 1.6%, sesquiterpene 0.6 ~ 1.5%, cachou extract 0.5 ~ 1.3%, eburicoic acid 0.5 ~ 1.2%, watermiscible vitamin E 0.6 ~ 1.8%, hyaluronic acid 0.4 ~ 0.8%, olive oil 2.6 ~ 5.6%, MEIGUI CHUNLU 0.6 ~ 1.4%, triclosan 0.3 ~ 0.5%, succinic acid 0.8 ~ 2.4%, ethanol 5.0 ~ 8.0%, surplus is distilled water, described lotion also comprises adjuvant: pH value regulator 1.0 ~ 4.2%, surfactant 1.5 ~ 2.3%, antiseptic 1.2 ~ 1.8%, stabilizing agent 0.9 ~ 1.3%.
2. a kind of compound recipe male privates nursing lotion as claimed in claim 1, it is characterized in that, described ethanol is mass concentration is 55 ~ 65%.
3. a kind of compound recipe male privates nursing lotion as claimed in claim 1, it is characterized in that, described pH value regulator is: lactic acid and sodium bicarbonate, citric acid and sodium dihydrogen phosphate wherein one or several.
4. a kind of compound recipe male privates nursing lotion as claimed in claim 1, it is characterized in that, described surfactant is: cocos nucifera oil both sexes sodium acetate, lauryl amidopropyl amine oxide, 1-isobutyl-3,5-dimethylhexylphosphoric acid potassium, alkyl polyglucoside class wherein one or several.
5. a kind of compound recipe male privates nursing lotion as claimed in claim 1, it is characterized in that, described antiseptic is: sodium benzoate, hibitane, ethyl hydroxybenzoate, phenoxyethanol wherein one or several.
6. a kind of compound recipe male privates nursing lotion as claimed in claim 1, it is characterized in that, described stabilizing agent is: hydroxyethyl-cellulose, D-trehalose, xanthan gum, sorbitol, ethylenediaminetetraacetic acid wherein one or several.
7. a kind of compound recipe male privates nursing lotion as claimed in claim 1, is characterized in that preparation method is:
Step one: Styrax and olive oil are mixed grease according to the weight ratio mix homogeneously of 1:2 is obtained, for subsequent use;
Step 2: make it fully dissolve according to the weight ratio mixing post-heating of 1:5 ~ 20 to stirring after 95 ~ 100 DEG C cachou extract and distilled water, aggregate into unformed tannin, to be cooledly to room temperature, add obtained mixed liquor after terpineol, Taxifolin, sesquiterpene, eburicoic acid %, watermiscible vitamin E, hyaluronic acid, MEIGUI CHUNLU, triclosan, succinic acid, ethanol respectively, leave standstill 8 ~ 12h, for subsequent use;
Step 3: mixed liquor prepared by mixing grease step one prepared and step 2 is uniformly mixed under mechanical action, add surfactant, antiseptic, stabilizing agent simultaneously, after making it fully dissolve, add pH value regulator adjust ph, and then to be placed in homogenizer after homogenizing process 15 ~ 30min, be the ultrafiltration post ultrafiltration of 6000 ~ 8000 again through the molecular weight that dams, obtain ultrafiltrate, seal up for safekeeping after packaging and namely obtain described compound recipe male privates nursing lotion.
8. a kind of compound recipe male privates nursing lotion as claimed in claim 1, is characterized in that, described compound recipe male privates nursing lotion pH value is 6.0 ~ 7.0.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106726780A (en) * | 2017-01-11 | 2017-05-31 | 珠海聚焦先导生物研究院有限公司 | A kind of women privates nurses shower cream |
| CN109481729A (en) * | 2018-11-23 | 2019-03-19 | 南京华开生物科技有限公司 | A kind of low molecular weight sodium hyaluronate isotonic liquid dressing and preparation method thereof |
| CN115282170A (en) * | 2022-08-11 | 2022-11-04 | 山东舒达生物科技有限公司 | Preparation method of powerful private lotion |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101161259A (en) * | 2006-10-13 | 2008-04-16 | 朱圣华 | A Chinese medicine lotion for preventing and controlling male and female pudendum disease |
| CN102018796A (en) * | 2010-06-25 | 2011-04-20 | 杭州易舒特药业有限公司 | Rinse-free concentrated clear traditional Chinese medicinal itching-relieving lotion |
| CN102671084A (en) * | 2012-04-21 | 2012-09-19 | 廖天源 | Medicine of male genital organ cleaning lotion and preparation method thereof |
| CN103070806A (en) * | 2013-02-04 | 2013-05-01 | 山西振东家庭健康护理用品有限公司 | Chinese medicinal anti-bacteria cleaning care solution and preparation method thereof |
| CN103800510A (en) * | 2014-02-18 | 2014-05-21 | 扈建民 | External washing liquor composition and preparation method thereof |
| CN105362792A (en) * | 2015-12-23 | 2016-03-02 | 焦福艳 | Nanometer Chinese herbal medicine care solution for pruritus vulvae and preparation method of care solution |
| CN105362785A (en) * | 2015-12-17 | 2016-03-02 | 武明霞 | Medicine composition for treating primary hypertension and preparation method thereof |
| CN105396006A (en) * | 2015-11-29 | 2016-03-16 | 苏赵珍 | Male topical lotion for preventing balanitis and preparation method thereof |
| CN105770867A (en) * | 2016-03-11 | 2016-07-20 | 王巧玲 | Tablets for treating tuberculous pericarditis and preparation method thereof |
| CN105797133A (en) * | 2016-05-03 | 2016-07-27 | 刘惠平 | Tablet for treating hysteromyoma and preparation method thereof |
-
2016
- 2016-01-25 CN CN201610049850.XA patent/CN105535170A/en active Pending
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101161259A (en) * | 2006-10-13 | 2008-04-16 | 朱圣华 | A Chinese medicine lotion for preventing and controlling male and female pudendum disease |
| CN102018796A (en) * | 2010-06-25 | 2011-04-20 | 杭州易舒特药业有限公司 | Rinse-free concentrated clear traditional Chinese medicinal itching-relieving lotion |
| CN102671084A (en) * | 2012-04-21 | 2012-09-19 | 廖天源 | Medicine of male genital organ cleaning lotion and preparation method thereof |
| CN103070806A (en) * | 2013-02-04 | 2013-05-01 | 山西振东家庭健康护理用品有限公司 | Chinese medicinal anti-bacteria cleaning care solution and preparation method thereof |
| CN103800510A (en) * | 2014-02-18 | 2014-05-21 | 扈建民 | External washing liquor composition and preparation method thereof |
| CN105396006A (en) * | 2015-11-29 | 2016-03-16 | 苏赵珍 | Male topical lotion for preventing balanitis and preparation method thereof |
| CN105362785A (en) * | 2015-12-17 | 2016-03-02 | 武明霞 | Medicine composition for treating primary hypertension and preparation method thereof |
| CN105362792A (en) * | 2015-12-23 | 2016-03-02 | 焦福艳 | Nanometer Chinese herbal medicine care solution for pruritus vulvae and preparation method of care solution |
| CN105770867A (en) * | 2016-03-11 | 2016-07-20 | 王巧玲 | Tablets for treating tuberculous pericarditis and preparation method thereof |
| CN105797133A (en) * | 2016-05-03 | 2016-07-27 | 刘惠平 | Tablet for treating hysteromyoma and preparation method thereof |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106726780A (en) * | 2017-01-11 | 2017-05-31 | 珠海聚焦先导生物研究院有限公司 | A kind of women privates nurses shower cream |
| CN109481729A (en) * | 2018-11-23 | 2019-03-19 | 南京华开生物科技有限公司 | A kind of low molecular weight sodium hyaluronate isotonic liquid dressing and preparation method thereof |
| CN115282170A (en) * | 2022-08-11 | 2022-11-04 | 山东舒达生物科技有限公司 | Preparation method of powerful private lotion |
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Application publication date: 20160504 |