CN105396006A - Male topical lotion for preventing balanitis and preparation method thereof - Google Patents

Male topical lotion for preventing balanitis and preparation method thereof Download PDF

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Publication number
CN105396006A
CN105396006A CN201510856167.2A CN201510856167A CN105396006A CN 105396006 A CN105396006 A CN 105396006A CN 201510856167 A CN201510856167 A CN 201510856167A CN 105396006 A CN105396006 A CN 105396006A
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parts
herba
balanitis
radix
fructus
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不公告发明人
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SU ZHAOZHEN
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SU ZHAOZHEN
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
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    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • AHUMAN NECESSITIES
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538Schizonepeta
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/58Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
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    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
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Abstract

The invention provides a male topical lotion for preventing balanitis. The male topical lotion is prepared from, by weight, 10-20 parts of purslane, 10-20 parts of oriental wormwood, 10-20 parts of indigo naturalis, 10-20 parts of rhizoma atractylodis, 10-20 parts of paris polyphylla, 10-20 parts of radix stemonae, 10-20 parts of cortex phellodendri, 10-20 parts of radix sophorae flavescentis, 10-20 parts of fructus kochiae, 10-20 parts of dittany bark, 10-20 parts of senecio scandens, 10-20 parts of rhizoma smilacis glabrae, 10-20 parts of verbena, 10-20 parts of fructus cnidii, 10-20 parts of dahurian patrinia herb, 10-20 parts of shikonin, 10-20 parts of dandelion, 10-20 parts of herba schizonepetae and 10-20 parts of melia toosendan. The male topical lotion has the advantages of being rapid in inflammation diminishing, thorough in sterilization, strong in inflammation diminishing and mite removal effect, convenient to apply, easy to prepare, low in cost and the like. The male topical lotion is small in toxic and side effect, convenient to use, short in cure time and free of relapse after cure. Both symptoms and root causes can be achieved, the appearance is nourished from the inside body, no relapse occurs after cure, and the male topical lotion is suitable for being used by a husband and a wife at the same time before intercourse.

Description

A kind of men's external wash liquid preventing and treating balanitis and preparation method thereof
Technical field
The present invention relates to the health product containing deriving from plant, animal or mineral component, particularly a kind of men's external wash liquid preventing and treating balanitis and preparation method thereof.
Background technology
The Prepuce balanitis cause of disease stimulates with redundant prepuce, smegma, local chemical factors and various infection relevant.In recent years, adult Prepuce balanitis patient showed increased, this and the opening of people's attitude towards sex, fornication increases, and it is relevant to abuse various cleaning agent.After having had unclean sexual behaviour, add various infection chance.In order to avoid catching sexually transmitted disease (STD), the cleaning agent cleaning and sterilizing pudendum of the much more personal external sterilizings of people, antiinflammatory.Some, in order to sterilize thoroughly, directly smear the cleaning agent stock solution of not diluting by a certain percentage repeatedly at prepuce of penis, glans penis skin part.Such local skin is subject to strong chemical stimulation and occurs redness, ooze out and occur acute inflammation.If acute inflammation deals with recurrent exerbation improperly, finally chronic Prepuce balanitis can be formed.
Prepuce balanitis is divided into acrobystitis and balanitis, owing to usually occurring therefore being called prepuce of penis balanitis simultaneously.This inflammation can be infective and noninfective, more common with infective Prepuce balanitis clinically.Infective normal due to contaminated intercourse, infect Candida albicans, infusorian, chlamydia, mycoplasma, diplococcus or other antibacterials and caused; Mostly non-infective agent is due to redundant prepuce, not clean, the unclean thing between foreskin and glans penis, i.e. smegma, just can pile up, and stimulates the foreskin of local and mucosa to be inflamed.
Balanitis is very large to male reproductive health harm, is mainly manifested in: 1, endanger reproductive system healthy: Prepuce balanitis easily causes the inflammation of the organs such as prostatitis, orchitis, epididymitis, deferent duct.If can not timely and effectively treat, mutual concurrent infection, can cause very large injury to healthy reproduction; 2, cause diseases of urinary system: Prepuce balanitis also easily causes the up infection of urinary system, is more common in cystitis, nephritis, pyelonephritis etc., acute stage morbidity is dealt with improperly can threat to life; 3, cause sexual dysfunction: the Prepuce balanitis disease phase, glans part sexuality answers the neural damage by inflammation, makes male's easy premature ejaculation in sexual life, and then causes the generation of sexual impotence; 4, infertility is caused: because the rheuminess thing hidden in foreskin enters vagina in coitus together with seminal fluid, reduce semen quality, and destroy spermiovum, cause sterile generation; 5, cause drying property occlusive balanitis: be a kind of pathology damage that Prepuce balanitis is more serious, not only destroy the normal physiological structure of foreskin glans penis and attractive in appearance, couple's sexual life quality is also had a strong impact on.
The cause of disease of Prepuce balanitis: 1, non-infective agent comprises the stimulations such as local wound, friction, contraceptive, soap and cleaning agent, it is even hemorrhage that local can show as edematous erythema, erosion, sepage, if secondary bacterial infection can suppurate and form ulcer surface.Patient pain is obvious, handicapped.Be referred to as acute shallow balanitis clinically.2, monilial infection candidiasis is a kind of opportunistic fungus, therefore candidal balanitis is often secondary to diabetes, after old wasting diseases and a large amount of antibiotic or hormone therapy, also can be constitutional, how to be transmitted by spouse's candidal vaginitis, glans penis and coronary sulcus can have light red erosion and thin-walled pustule, but local often can not find candidiasis, may caused by the microbial local anaphylaxis of beads.3, ameba infected patient is many first Prepuce balanitis pathological changes, and local loses normal barrier action, is then infected by intestinal amebiasis and causes.Obviously, secretions direct smear can find ameba for local erosion, ulcer, tissue necrosis.4, trichomonacide is many suffers from trichomonal vaginitis and infected because of spouse.Symptom is comparatively light, and main manifestations is that glans part plays erythematous papules, phlysis etc.Boundary is clear, scope expands gradually, and patient often feels pruritus.Infusorian can be found in secretions.In addition, also have some balanitis etiology unknowns true, but redundant prepuce, smegma stimulates how relevant with the generation of balanitis.Therefore male also often should clean the lower part of the body, keep local to clean, avoid stimulating.Redundant prepuce person, can carry out posthetomy after inflammation controls.Although the pathogen of Prepuce balanitis is more and morbidity complicated, in actual clinical, all can there is some similar symptoms.As foreskin redness, causalgia, urinate time increase the weight of, purulent secretion can be had to flow out from ostium praeputiale.As overturn by foreskin, visible Inner prepuce and Glans penis hyperemia, swelling, severe one can have shallow aphtha or erosion, and performance has pus; Or glans penis pimpling and erythema, expand gradually, clear-cut margin, in erythema, visible pinhead-sized phlysis, finally forms rotten to the corn face; Or glans part plays erythematous papules, phlysis etc.Boundary is clear, scope expands gradually, and patient often feels pruritus.Balanitis can cause due to infection and non-infection.Due to contaminated intercourse, infect Candida albicans, infusorian, chlamydia, mycoplasma and gonorrhea diplococcus, all can cause Prepuce balanitis.Mostly non-infective agent is due to redundant prepuce, not clean, the unclean thing between foreskin and glans penis, i.e. smegma, just can pile up, and stimulates the foreskin of local and mucosa to be inflamed.
Balanitis due to the understanding deficiency of patient to balanitis and lack of standardization, the improper treatment of doctor, also makes the recurrent exerbation harm aggravation of Prepuce balanitis in actual clinical.1. easily out in the cold and lose control.Because Prepuce balanitis sickness rate is high, initial symptoms is comparatively light, bad during fashion, so easily out in the cold in daily life, until serious time medical.To time medical with complication and complication, larger damage has been caused to healthy reproduction system, so early early treatment must be checked.2. think sexually transmitted disease (STD) by mistake and wrong treatment.When there is balanitis, most of patients thinks sexually transmitted disease (STD), the cleaning agent of personal external sterilizing antiinflammatory, such local skin be subject to strong chemical stimulation occur red and swollen, ooze out and exacerbate inflammatory reaction, finally can form chronic Prepuce balanitis.And the doctor that some Clinics is not good, or be deliberately used as treatment for the sexually transmitted diseases because of advantage factors, to patient body with cause very large injury economically.3. nonstandard traditional remedies limited efficiency.Nonstandard treatment makes Relapse rate show effect clinically, simultaneously because the Prepuce balanitis course of disease is long, antibioticly lack of standardizationly use and abuse, pathogenic bacteria easily produces drug resistance etc., traditional treatment is made not reach desirable effect, long-term chronic inflammation impacts urogenital health, occurs prostatitis, the diseases such as impotence and premature ejaculation.4. the factor such as redundant prepuce is easily out in the cold.The key factor that redundant prepuce is also Prepuce balanitis morbidity and does not repeatedly heal, if do not carry out the treatment of redundant prepuce, pathogenic bacteria and rheuminess thing easily conceal with foreskin in directly act on diseased region or new organizational structure, aggravate one's illness or the focus of causing property, if so there is redundant prepuce and need and early treatment.
Summary of the invention
Technical problem to be solved by this invention is, because primary disease position is concealed, a lot of people is reluctant hospitalize; Treat lack of standardization: nonstandard treatment makes Relapse rate show effect clinically, simultaneously because the Prepuce balanitis course of disease is long, antibioticly lack of standardizationly use and abuse, pathogenic bacteria easily produces drug resistance etc., traditional treatment is made not reach desirable effect, long-term chronic inflammation impacts urogenital health, occurs prostatitis, the diseases such as impotence and premature ejaculation; Clinically make decoction oral with Chinese physician with disease foreign side, and some Chinese medicine lotions, but therapeutic effect is all not satisfactory, also exists and can bring out the deficiencies such as drug resistance, relapse rate is high, medication is inconvenient, preparation is difficult.Now in the urgent need to providing a kind of instant effect, side effect is little, biocidal property is strong, effect men's external wash liquid rapidly, efficient solution can remove the misery of patient, treat this disease.
For solving the problems of the technologies described above, the invention provides a kind of men's external wash liquid preventing and treating balanitis, in described men's external wash liquid, the parts by weight of various crude drug are: Herba Portulacae 10 ~ 20 parts, Herba Artemisiae Scopariae 10 ~ 20 parts, Indigo Naturalis 10 ~ 20 parts, Rhizoma Atractylodis 10 ~ 20 parts, Rhizoma Paridis 10 ~ 20 parts, the Radix Stemonae 10 ~ 20 parts, Cortex Phellodendri 10 ~ 20 parts, Radix Sophorae Flavescentis 10 ~ 20 parts, the Fructus Kochiae 10 ~ 20 parts, Cortex Dictamni 10 ~ 20 parts, Herba Senecionis Scandentis 10 ~ 20 parts, Rhizoma Smilacis Glabrae 10 ~ 20 parts, Herba Verbenae 10 ~ 20 parts, Fructus Cnidii 10 ~ 20 parts, Herba Patriniae 10 ~ 20 parts, Radix Arnebiae (Radix Lithospermi) 10 ~ 20 parts, Herba Taraxaci 10 ~ 20 parts, Herba Schizonepetae 10 ~ 20 parts, Fructus Toosendan 10 ~ 20 parts.
The described men's external wash liquid preventing and treating balanitis, in men's external wash liquid described in it, the parts by weight of various crude drug can be: Herba Portulacae 10 ~ 15 parts, Herba Artemisiae Scopariae 10 ~ 15 parts, Indigo Naturalis 10 ~ 15 parts, Rhizoma Atractylodis 10 ~ 15 parts, Rhizoma Paridis 10 ~ 15 parts, the Radix Stemonae 10 ~ 15 parts, Cortex Phellodendri 10 ~ 15 parts, Radix Sophorae Flavescentis 10 ~ 15 parts, the Fructus Kochiae 10 ~ 15 parts, Cortex Dictamni 10 ~ 20 parts, Herba Senecionis Scandentis 10 ~ 20 parts, Rhizoma Smilacis Glabrae 10 ~ 20 parts, Herba Verbenae 10 ~ 20 parts, Fructus Cnidii 10 ~ 20 parts, Herba Patriniae 10 ~ 20 parts, Radix Arnebiae (Radix Lithospermi) 10 ~ 20 parts, Herba Taraxaci 10 ~ 20 parts, Herba Schizonepetae 10 ~ 20 parts, Fructus Toosendan 10 ~ 20 parts.
The described men's external wash liquid preventing and treating balanitis, in men's external wash liquid described in it, the parts by weight of various crude drug can also be: Herba Portulacae 10 ~ 20 parts, Herba Artemisiae Scopariae 10 ~ 20 parts, Indigo Naturalis 10 ~ 20 parts, Rhizoma Atractylodis 10 ~ 20 parts, Rhizoma Paridis 10 ~ 20 parts, the Radix Stemonae 10 ~ 20 parts, Cortex Phellodendri 10 ~ 20 parts, Radix Sophorae Flavescentis 10 ~ 20 parts, the Fructus Kochiae 10 ~ 20 parts, Cortex Dictamni 10 ~ 15 parts, Herba Senecionis Scandentis 10 ~ 15 parts, Rhizoma Smilacis Glabrae 10 ~ 15 parts, Herba Verbenae 10 ~ 15 parts, Fructus Cnidii 10 ~ 15 parts, Herba Patriniae 10 ~ 15 parts, Radix Arnebiae (Radix Lithospermi) 10 ~ 15 parts, Herba Taraxaci 10 ~ 15 parts, Herba Schizonepetae 10 ~ 15 parts, Fructus Toosendan 10 ~ 15 parts.
For solving the problems of the technologies described above, the present invention also provides a kind of preparation method of preventing and treating the men's external wash liquid of balanitis, and the preparation process of described men's external wash liquid comprises:
A. described crude drug is put into pulverizer grinding and sieving,
B. the particulate matter be left after sieving is put into ethanol heating and refluxing extraction 2 times;
C. the medicinal residues after above-mentioned ethanol extraction are got again, the heating and refluxing extraction that adds water 2 times;
D. above-mentioned two kinds of extracting solution are merged concentrated; Add potassium permanganate solution to stir, canned after disinfection by ultraviolet light.
In described step a, described crude drug can be put into after pulverizer is pulverized and cross 100 order dusting covers, the enable fine powder amount by 100 mesh sieves is reaching 30%, collects by the raw material fine powder of 100 mesh sieves for subsequent use.
In described step b, the coarseparticulate be left after sieving can be put into ethanol heating and refluxing extraction 2 times, each 1 ~ 2 hour, 2 extracting solution be merged and leaves standstill;
In described step c, the medicinal residues that above-mentioned ethanol extraction is crossed can be added 10 times of water gaging heating and refluxing extraction 2 times, each 1 ~ 2 hour, 2 extracting solution be merged and leaves standstill.
In described steps d, above-mentioned two kinds of extracting solution can be merged, when concentrating under reduced pressure relative density is 80 DEG C 1.37 filtrate, reclaim ethanol, by gained filtrate adjustment proportion to 1.60, stir evenly after adding the fine powder sieved; Pour in 0.5% potassium permanganate solution, stir, with canned after disinfection by ultraviolet light.
For solving the problems of the technologies described above, the present invention reoffers a kind of preparation method of preventing and treating the men's external wash liquid of balanitis, and the preparation process of described men's external wash liquid agent comprises further: mixed by described crude drug, chopping, soaks; 2 extracting solution each 1 ~ 2 hour, are merged and leave standstill by just soaked crude drug heating and refluxing extraction 2 times; Again the medicinal residues that above-mentioned water extraction is crossed are added 5 ~ 8 times amount 60 ~ 70% alcohol heating reflux and extract 2 times, each 1 ~ 2 hour, 2 extracting solution are merged and leaves standstill; Above-mentioned two kinds of extracting solution are merged, when concentrating under reduced pressure relative density is 80 DEG C 1.35 filtrate, reclaim ethanol, by gained filtrate adjustment proportion to 1.60, reduce pressure to obtain extractum, adds 0.5% potassium permanganate solution bath and stir, be mixed into the liquid of thickness, use after ultraviolet radiation for sterilizing and disinfecting.
For solving the problems of the technologies described above, the present invention also provides a kind of preparation method of preventing and treating the men's external wash liquid of balanitis, the preparation process of a described men's external wash liquid agent again step comprises: mixed by described crude drug, chopping, immersion decocts with water 2 times, collecting decoction, remove sediment, supernatant adds ethanol and filters, filtrate recycling ethanol is to clean, finally be equivalent to 1g crude drug with purified water adjustment medicine liquid volume to every milliliter of medicinal liquid, medicinal liquid is that yellowish-brown is to brown liquid, add 0.5% potassium permanganate solution bath to stir, be mixed into the liquid of thickness, use after ultraviolet radiation for sterilizing and disinfecting.
Washing liquid of the present invention takes washout or demibain, each 20 ~ 30mL, every day 2 times.General was 1 course for the treatment of with 10d, observe the curative effect after 2 ~ 3 courses for the treatment of.
Compared with prior art teach, the present invention has sterilization thoroughly, and antiinflammatory deinsectization effect is strong, and antiinflammatory, antipruritic effect are good; And convenient drug administration, the advantages such as medicinal liquid is easy to manufacture, with low cost; And safety, have no side effect, easy to use, healing time is short, not easily recurs after healing.Especially be applicable to cleaning privates before man and wife has sexual intercourse.Can good social value and economic interests be created, there is wide DEVELOPMENT PROSPECT.
Detailed description of the invention
Prepuce balanitis is the common disease of male.If we find that this sick malpractice can cause acrobystitis recurrent exerbation, cause ostium praeputiale, the small breach of inner panel dermal inflammatory occurs repeatedly.Cause scar hyperplasia through repeatedly healing, finally cause Inner prepuce inflammatory to thicken or with the adhesion of glans penis skin, ostium praeputiale forms hypertrophica stenosis ring.During erection, glans penis refers to Inner prepuce and balanic inflammation by Prepuce balanitis.A kind of lipid material of normal foreskin luminal sectetion, when redundant prepuce or phimosis, this type of material can be accumulated into smegma stimulates foreskin and Glans penis to cause Prepuce balanitis.If Prepuce balanitis obstinate, can cause, Secondary cases phimosis, external orifice stricture, anterior urethral stricture, prostatitis, sexual dysfunction, male sterility etc.
For the prophylactic treatment of balanitis, often cleaning foreskin and Glans penis, keep foreskin intracavity clean and dry, acrobystitis can be prevented completely.Should note at ordinary times cultivating good health habits, fine preventive effect is had to redundant prepuce or phimosis (foreskin can not overturn) person's row posthetomy etc., if this disease is once find, in affected part by foreskin upset potassium permanganate liquid soaking and washing, how suitable application antibiotic, cure within a couple of days; If comparatively serious, effectively need treat under physician guidance.Smegma or vegetative place, residual urine and smegma have been mixed to form the natural medium ground of antibacterial, easily cause foreskin and Glans penis inflammation.Occur in the inflammation of urethral orifice, urethral orifice can be caused after healing narrow and small, cause dysuria.In addition, the patient of 85%-95% is about had to have phimosis or redundant prepuce medical history.This may also be that smegma causes.Do not clear up smegma for a long time, can cause adherent prepuce, feel pain when making foreskin overturn, the serious foreskin that also can make cannot overturn up.The smegma that redundant prepuce brings makes prepuce of penis adhesion, is understand the feels pain because foreskin upset is difficult having sexual intercourse.And smegma also can take antibacterial in fragile responsive vagina to.Your sex partner is made to suffer from like this disease.The too much smegma that all these bad impacts all bring with redundant prepuce is relevant.The way of putting things right once and for all of the harm that solution foreskin phimosis and smegma bring carries out once simple Wrapping annulus cuts operation, if but do not want to carry out Wrapping annulus cuts operation, want again the health of keeping fit, preferably the simplest way often cleans foreskin, cleaning smegma.When redundant prepuce is not as resetted after turning on by force, can paraphimosis tion of paraphimosis be caused, because glans penis may be caused downright bad, hospital must be arrived at once and ask for help.During cleaning smegma, due to due to Inner prepuce profit thinner than outside plate, more responsive to chemical cleaner, so can not use irritating detergent, clear water rinses.The relatively mild fancy soap of character, shower lotion are also passable.
Primary disease one side and endogenous cause of ill: liver,kidney,spleen malfunction closes, and the liver pulse is around external genitals, and main store blood is again viscus attriguted to wind and wood; Kidney controlling essence storage, main reproduction, have one's ideas straightened out Yu Eryin; The spleen has the function to transport and transform nutrients, and water wets.If dampness-heat of the liver or the life of stagnation of liver-QI with deficiency of the spleen fire-transformation are wet, damp and hot heresy, with through bet, pents up external genitals so pudendal pruritus; Or deficiency of the liver and kindey, blood and essence asthenia, raw air slaking are not dry, pudendum failure of skin and muscle to be nourished, flourish and itch; Infect the sick worm of damp in addition on the one hand with exopathogenic factor relevant, careless because taking the photograph body, cause the sick worm of damp and invade, worm disturbs pudendum, sends out as pudendal pruritus.Traditionally theory of Chinese medical science, caused by endogenous cause of ill, person is based on oral medicine adjustment function, and because of person caused by exterior syndrome worm or be aided with external treatment or be Main Means with external treatment.
Because Prepuce balanitis sickness rate is high, initial symptoms is comparatively light, bad during fashion, so easily out in the cold in daily life, until serious time medical.To time medical with complication and complication, larger damage has been caused to healthy reproduction system, so early early treatment must be checked.When there is balanitis, most of patients thinks sexually transmitted disease (STD), the cleaning agent of personal external sterilizing antiinflammatory, such local skin be subject to strong chemical stimulation occur red and swollen, ooze out and exacerbate inflammatory reaction, finally can form chronic Prepuce balanitis.And the doctor that some Clinics is not good, or be deliberately used as treatment for the sexually transmitted diseases because of advantage factors, to patient body with cause very large injury economically.
Fructus Kochiae clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching.For difficulty and pain in micturition, pudendal pruritus leukorrhagia, rubella, eczema, skin pruritus." property of medicine opinion ": " with Actinolitum with taking, main husband's impotence does not rise, QI invigorating benefit power; Control cloudy ovum Huang disease, reduce phlegm and internal heat wind, can make soup and take a shower." to rabbit gavage, in 6 hours, urine chloride increases by 127.1% ~ 131.6% to Fructus Kochiae decoct 2g/kg, but total volume of urine is unchanged. and have report to point out, the Fructus Kochiae all has impact to rat urine volume and renal sodium excretion.
Cortex Phellodendri heat clearing and damp drying, pathogenic fire purging removes steams, detoxification sore treatment.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity is warded off, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency." Chinese Pharmacopoeia " carries the power of Cortex Phellodendri heat clearing and damp drying, similar to Radix Arnebiae (Radix Lithospermi), Rhizoma Coptidis, but being good except the damp and hot of the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels.
Radix Sophorae Flavescentis is bitter, cold.GUIXIN, liver, stomach, large intestine, urinary bladder channel heat clearing and damp drying, parasite killing, diuresis.For hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy; External treatment colpitis mycotica, is often combined with Cortex Phellodendri, is the colpitic external use gynaecological good medicine for the treatment of.
Radix Stemonae nature and flavor sweetness and bitterness, tepor." not Lu ": tepor." property of medicine opinion ": sweet in the mouth, nontoxic." Japan hanako materia medica ": bitter in the mouth, nontoxic.Nature and flavor are sweet, bitter, tepor.Return lung meridian.Function cures mainly nourishing the lung to keep the adverse QI downward cough-relieving, parasite killing.Cough for new chronic cough, pulmonary tuberculosis cough, pertussis; Outer for head louse, body louse, enterobiasis, pudendum Pruritus.
Cortex Dictamni dispels the wind, dampness, heat clearing away, removing toxic substances.Control wind heat sore, scabies, itchy skin eruption, rheumatic arthralgia, jaundice." herbal classic ": main wind syndrome of head, jaundice, cough with dyspnea, drenches drop, swells and ache in woman's the moon, the dead flesh of arthralgia chiefly caused by damp pathogen, unable to flex and stretch the extremities, start-stop, row step.
Rhizoma Smilacis Glabrae nature and flavor: sweet light are flat.Gui Jing: Liver Channel; Stomach warp; Spleen channel.Function: removing toxic substances, dehumidifying, sharp joint.Cure mainly: control syphilis, stranguria with turbid discharge, muscles and bones spasm and pain, beriberi, furuncle treats skin ulcer, carbuncle, scrofula.
Radix Arnebiae (Radix Lithospermi) removing heat from blood, invigorates blood circulation, removing toxic substances rash.Contain for heat in blood poison, macule purple is black, measles without adequate eruption, skin infection, eczema, burn due to hot liquid or fire.Clearing away heat and cooling blood, for measles, calentura skin eruption, eczema, hematuria, stranguria with blood, dysentery, skin infection, erysipelas, burn, constipation with heat retention.
Herba Patriniae nature and flavor hardship is flat, has effect of heat-clearing and toxic substances removing, evacuation of pus removing blood stasis with potent drugs.Acute appendicitis, dysentery, leucorrhea with red and white discharge, the stagnant stomachache of the stasis of blood in puerperal, conjunctival congestion and swelling pain can be cured.Enter stomach, large intestine, Liver Channel.Cure mainly heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, blood circulation promoting competent silt.For acute appendicitis, lung abscess and sore and toxic, the stagnant caused breast abdomen pain of the excess-heat stasis of blood, the diseases such as the stagnant stomachache of the stasis of blood in puerperal.
Herba Senecionis Scandentis, has another name called Herba Hieracii Umbellati, Herba Senecionis Scandentis.Latin name HerbaSenecionisScandentis.A kind of Chinese herbal medicine, under being born in hillside, sparse woods, Lin Bian, roadside, in limes marginis thick grass.The effects such as it is cold in nature, bitter in the mouth, has heat-clearing and toxic substances removing, improving eyesight, antipruritic.Be used for anemopyretic cold, conjunctival congestion and swelling pain, dysentery, skin eczema furuncle.Supplement to the Herbal: main pestilential pathogen, knot is yellow, malaria miasma, and cup poison, boils telling down of clothes, also smash the place of biting such as deposited skin ulcer, worm Serpentis dog.
Herba Verbenae promoting blood circulation to remove blood stasis, preventing the attack (or recurrence) of malaria, removing toxic substances, inducing diuresis to remove edema.For lump in the abdomen, amenorrhea dysmenorrhea, malaria, sore throat, carbuncle, edema, pyretic stranguria.
Containing multiple health-nutrition compositions such as taraxol, taraxacin, choline, organic acid, inulin in Herba Taraxaci plant, there are the effects such as diuresis, cathartic, jaundice eliminating subcutaneous ulcer, function of gallbladder promoting.Herba Taraxaci, simultaneously containing protein, fat, carbohydrate, trace element and vitamin etc., has abundant nutritive value, raw-eaten, stir-fry and eat, cook soup, is the plant of dietotherapeutic.Containing multiple health-nutrition compositions such as taraxol, taraxacin, choline, organic acid, inulin in Herba Taraxaci plant, there are the effects such as diuresis, cathartic, jaundice eliminating subcutaneous ulcer, function of gallbladder promoting.Herba Taraxaci containing protein, fat, carbohydrate, trace element and vitamin etc., has abundant nutritive value simultaneously.The carotene wherein contained and C and mineral, to the effect that dyspepsia, constipation are all improved.Leaf is also improved eczema in addition, the effect of dermatitis of releiving, and root then has antiinflammation, and flower decocts into medicine juice can remove freckle.
Fructus Cnidii is pungent, bitter, temperature; Slightly poisonous.Return kidney channel.Cure mainly warming the kidney to invigorate YANG, dampness, dispel the wind, parasite killing.For sexual impotence, cold womb, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago; External treatment vulval eczema, married woman's pudendal pruritus; Eczema scrotum is gynecological external use good medicine." Bencao Jingshu " carries: Fructus Cnidii, and bitter in the mouth is put down; " not Lu " be pungent sweet nontoxic; Modern its abnormal smells from the patient in detail, when warm-dryness syndrome of must holding concurrently, sun also.Therefore swell and ache in housewife people's the moon, man's impotence pruritus due to damp pathogen, except stagnated QI, sharp joint, malignant boil." not Lu " warming the middle warmer and descending qi, makes married woman's Zifu heat, and man is cloudy strong, has made us son.Lid can dehumidify with tongue, and temperature can cold expelling, pungently can moisten kidney, sweet energy strengthening the spleen, therefore can remove all deficiency and coldness of married woman man and to wet disease of viscera connecting with this channel.Cold-damp was both removed, then disease is gone, performance Yiyang, therefore can disease, and had tonification also.
Herba Verbenae herb hyoscine, has clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, antiinflammatory, quenches the thirst, diuresis; Seed improving eyesight.Modern study, Herba Verbenae is also containing abundant SL3 fatty acid and vitamin A sample material: SL3 fatty acid forms cell membrane, especially brain cell membrane and the necessary material of eye cell membrane; Vitamin A sample substance maintains epithelial tissue as skin, cornea and conjunctival normal function, participates in the synthesis of rhodopsin, strengthens retinal photoreceptor performance, also participates in many oxidizing processs in body.Herba Verbenae Herb be used as medicine there is removing toxic substances, inhibiting bacteria and diminishing inflammation, diuresis dysentery relieving, intestine moistening disappear stagnant, debug, the drug effect such as improving eyesight and suppression metrorrhagia; External can control the disease such as erysipelas, venom.
Herba Artemisiae Scopariae cold nature, acrid in the mouth, painstaking effort can cure mainly clearing away damp-heat, jaundice eliminating subcutaneous ulcer.For jaundice oliguria, eczema pruritus, infectious jaundice type hepatitis.Effect of Herba Artemisiae Scopariae.Clearing away heat-damp and promoting diuresis; Jaundice eliminating. cure mainly: jaundice; Dysuria; Eczema pruritus etc. the effects such as pharmaceutical research has function of gallbladder promoting, liver function protecting, antipyretic, antiinflammatory, blood fat reducing, blood pressure lowering, coronary dilating, certainly, this is the research that western medicine extraction Herba Artemisiae Scopariae composition is worked it out, the how bad judgement of effect in clinical practice.Herba Artemisiae Scopariae consumption is excessive causes dizziness, feels sick, diarrhoea, epigastric discomfort, acute Bile duct injury, but also has ARR report. and the Herba Artemisiae Scopariae of therapeutic dose generally can not cause serious damage.Herba Artemisiae Scopariae has significant hepatoprotective effect, to first, and hepatitis B, icterohepatitis, there is significant curative effect. there is function of gallbladder promoting, promote bile secretion, increase the effect that in bile, cholic acid and bilirubin are discharged. heart coronary flow can be increased, improve microcirculation, and have blood pressure lowering, blood fat reducing, anticoagulation, diuresis is antipyretic relievings asthma, and drives away ascarid and suppresses the effect of multiple pathogenic dermatophytes and antibacterial.
Indigo Naturalis has heat clearing away, removing heat from blood, effect of removing toxic substances, and property is sweet, flat, nontoxic, enters liver, lung, stomach warp.Heat-clearing and toxic substances removing, removing heat from blood, arresting convulsion, for maculae caused by violent heat pathogen, heat in blood tells nosebleed, chest pain hemoptysis, aphtha, mumps, carries: except thermal detoxification according to " key medicine divides agent ", and holding concurrently can removing heat from blood." Thunder God concocts property of medicine solution " carries: " enter liver, spleen two warp.”
Rhizoma Atractylodis are drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For distension and fullness in the abdomen, edema of having loose bowels, beriberi flaccidity of feet with lamenness, rheumatic arthralgia, anemofrigid cold, nyctalopia.Rhizoma Atractylodis have drying damp and strengthening spleen, effect of wind-damp dispelling.Cure mainly retention of dampness in middle-JIAO, anemofrigid-damp arthralgia, foot swelling and pain in knee, flaccidity is soft unable, nyctalopia nyctalopia." pearl sac " day: " stomach invigorating can pacify spleen, non-this of all damp-edema can not remove." Compendium of Material Medica says: " control damp-phlegm prolonged fluid-retention ... and spleen wets dirty, turbid drop leukorrhagia, slidingly rush down hemorrhoidal hamorrhage." " Newly Revised Canon of Materia Medica " claim it can " diuresis ".
Rhizoma Paridis, Classification system ParispolyphyllaSm. GUIXIN warp, Liver Channel, lung meridian, stomach warp, large intestine channel.Relieve internal heat anticancer, reducing swelling and alleviating pain, heat clearing away arresting convulsion, antitussive and antiasthmatic.Controlling the diseases such as carbuncle pulmonary tuberculosis chronic cough, traumatic injury, snake bite and insect sting, lymphoid tuberculosis, osteomyelitis, is one of main component of YUNNAN BAIYAO.There is stronger bacteriostasis to Asia influenza A virus, all have bacteriostasis to dysentery bacterium, Salmonella paratyphi, Salmonella, paracolon, bacillus pyocyaneus, staphylococcus aureus, Hemolytic streptococcus, meningococcus etc.
Herba Schizonepetae taste is put down, and warm in nature, nontoxic, faint scent is dense.Herba Schizonepetae is diaphoresis, antipyretic, is one of conventional medical herbs of China.Can town expectorant, timid wind, removing heat from blood.Control influenza, the diaphoresis of headache cold and heat, vomiting.Dispel the wind; Induce sweat; Rash; Hemostasis.Main cold, fever; Headache; Eye itching; Cough; Laryngopharynx swelling and pain; Measles; Carbuncle; Skin ulcer scabies; Epistaxis; Spit blood; Have blood in stool; Metrorrhagia; Puerperal blood faints.For flu, headache, measles, rubella, skin infection from the beginning of.Parch to black treating hematochezia, metrorrhagia, puerperal blood faints." herbal classic ": main cold and heat, scrofula, the raw skin ulcer of scrofula, broken knot gather qi together, lower blood stasis, except arthralgia chiefly caused by damp pathogen." property of medicine opinion ": control aversion to wind harmful wind, the askew heresy of actinal surface, insensitive impediment all over, has a guilty conscience and forgets things, and beneficial power adds grain.The main poison that exorcises evil spirits, except labor, controls fourth and swells; Get one to hold and cut, with five liters, water, boil and get two liters, cold point two clothes, main promoting blood circulation, transmit the not enough gas of the five internal organs, can diaphoresis, except cold wind; Smash again end and vinegar envelope poison swell.
Fructus Toosendan is cold in nature, bitter in the mouth, is the one of qi-activating drug.Mainly enter Liver Channel, catharsis liver-heat, promoting the circulation of QI to relieve pain, have the function except damp and hot, clearing away liver-fire, pain relieving, parasite killing.Except damp and hot, clearing away liver-fire, pain relieving, parasite killing.Control epigastric pain with cold limbs due to adverseness of heat, hypochondriac pain, colic, abdominal pain due to worm stagnation." herbal classic ": " main temperature disease, typhoid fever are too hot tired mad, kill three scabies and steal, diuresis water channel.″
Embodiment 1: washing liquid preparation process of the present invention is: by described crude drug Herba Portulacae 1000g, Herba Artemisiae Scopariae 1000g, Indigo Naturalis 1000g, Rhizoma Atractylodis 1000g, Rhizoma Paridis 1000g, Radix Stemonae 1000g, Cortex Phellodendri 1000g, Radix Sophorae Flavescentis 1000g, Fructus Kochiae 1000g, Cortex Dictamni 1000g, Herba Senecionis Scandentis 1000g, Rhizoma Smilacis Glabrae 1000g, Herba Verbenae 1000g, Fructus Cnidii 1000g, Herba Patriniae 1000g, Radix Arnebiae (Radix Lithospermi) 1000g, Herba Taraxaci 1000g, Herba Schizonepetae 1000g, Fructus Toosendan 1000g.Put into after pulverizer is pulverized and cross 100 order dusting covers, the enable fine powder amount by 100 mesh sieves is reaching 30%, collects by the raw material fine powder of 100 mesh sieves for subsequent use.The coarseparticulate be left after sieving is put into ethanol heating and refluxing extraction 2 times, each 1 ~ 2 hour, 2 extracting solution is merged and leaves standstill.The medicinal residues that above-mentioned ethanol extraction is crossed are added 10 times of water gaging heating and refluxing extraction 2 times, each 1 ~ 2 hour, 2 extracting solution are merged and leaves standstill.Above-mentioned two kinds of extracting solution are merged, when concentrating under reduced pressure relative density is 80 DEG C 1.35 filtrate, reclaim ethanol, by gained filtrate adjustment proportion to 1.06, add 0.5% potassium permanganate solution bath to stir, be mixed into the liquid of thickness, use after ultraviolet radiation for sterilizing and disinfecting.
Embodiment 2: the manufacturing process of washing liquid of the present invention can also be: by crude drug Herba Portulacae 1300g, Herba Artemisiae Scopariae 1300g, Indigo Naturalis 1200g, Rhizoma Atractylodis 1300g, Rhizoma Paridis 1400g, Radix Stemonae 1200g, Cortex Phellodendri 1300g, Radix Sophorae Flavescentis 1300g, Fructus Kochiae 1400g, Cortex Dictamni 1200g, Herba Senecionis Scandentis 1100g, Rhizoma Smilacis Glabrae 1200g, Herba Verbenae 1300g, Fructus Cnidii 1200g, Herba Patriniae 1300g, Radix Arnebiae (Radix Lithospermi) 1100g, Herba Taraxaci 1300g, Herba Schizonepetae 1200g, Fructus Toosendan 1300g.First described crude drug is ground into coarse powder, then pulverizes further, cross 100 mesh sieves, the enable fine powder amount by 100 mesh sieves is reaching 30%, collects and obtains fine powder a by the fine powder of 100 mesh sieves; Again the coarse powder not by 100 mesh sieves is dropped into multi-function extractor and extract twice, first time adds 8-10 times amount ethanol and decocts 1-2 hour, and second time adds 4-8 times amount soak by water 1-2 hour, merges twice decocting liquid, filters to get filtrate; Heating is concentrated into pasty state, and become coarse granule extracting solution b, the fine powder a adding preparation puts into coarse granule extracting solution b, adds 0.5% potassium permanganate solution bath and stirs, be mixed into the liquid of thickness, use after ultraviolet radiation for sterilizing and disinfecting.
Embodiment 3: the manufacturing process of washing liquid of the present invention also can be: by Herba Portulacae 1400g, Herba Artemisiae Scopariae 1300g, Indigo Naturalis 1200g, Rhizoma Atractylodis 1100g, Rhizoma Paridis 1400g, Radix Stemonae 1200g, Cortex Phellodendri 1300g, Radix Sophorae Flavescentis 1300g, Fructus Kochiae 1400g, Cortex Dictamni 1200g, Herba Senecionis Scandentis 1100g, Rhizoma Smilacis Glabrae 1400g, Herba Verbenae 1300g, Fructus Cnidii 1200g, Herba Patriniae 1200g, Radix Arnebiae (Radix Lithospermi) 1100g, Herba Taraxaci 1400g, Herba Schizonepetae 1300g, Fructus Toosendan 1300g.Mixing, chopping, soaks and decocts with water 2 times, collecting decoction, remove sediment, supernatant adds ethanol and filters, and filtrate recycling ethanol, to clean, is finally equivalent to 1g crude drug with purified water adjustment medicine liquid volume to every milliliter of medicinal liquid, medicinal liquid is that yellowish-brown is to brown liquid, add 0.5% potassium permanganate solution bath to stir, be mixed into the liquid of thickness, use after ultraviolet radiation for sterilizing and disinfecting.
This washing liquid takes washout or demibain, each 20 ~ 30mL, every day 2 times.General was 1 course for the treatment of with 10d, observe the curative effect after 2 ~ 3 courses for the treatment of.

Claims (3)

1. prevent and treat the men's external wash liquid of balanitis for one kind, it is characterized in that, in described men's external wash liquid, the parts by weight of various crude drug comprise: Herba Portulacae 10 ~ 20 parts, Herba Artemisiae Scopariae 10 ~ 20 parts, Indigo Naturalis 10 ~ 20 parts, Rhizoma Atractylodis 10 ~ 20 parts, Rhizoma Paridis 10 ~ 20 parts, the Radix Stemonae 10 ~ 20 parts, Cortex Phellodendri 10 ~ 20 parts, Radix Sophorae Flavescentis 10 ~ 20 parts, the Fructus Kochiae 10 ~ 20 parts, Cortex Dictamni 10 ~ 20 parts, Herba Senecionis Scandentis 10 ~ 20 parts, Rhizoma Smilacis Glabrae 10 ~ 20 parts, Herba Verbenae 10 ~ 20 parts, Fructus Cnidii 10 ~ 20 parts, Herba Patriniae 10 ~ 20 parts, Radix Arnebiae (Radix Lithospermi) 10 ~ 20 parts, Herba Taraxaci 10 ~ 20 parts, Herba Schizonepetae 10 ~ 20 parts, Fructus Toosendan 10 ~ 20 parts.
2. prevent and treat the men's external wash liquid of balanitis according to claim 1, it is characterized in that, in described men's external wash liquid, the parts by weight of various crude drug are: Herba Portulacae 10 ~ 15 parts, Herba Artemisiae Scopariae 10 ~ 15 parts, Indigo Naturalis 10 ~ 15 parts, Rhizoma Atractylodis 10 ~ 15 parts, Rhizoma Paridis 10 ~ 15 parts, the Radix Stemonae 10 ~ 15 parts, Cortex Phellodendri 10 ~ 15 parts, Radix Sophorae Flavescentis 10 ~ 15 parts, the Fructus Kochiae 10 ~ 15 parts, Cortex Dictamni 10 ~ 20 parts, Herba Senecionis Scandentis 10 ~ 20 parts, Rhizoma Smilacis Glabrae 10 ~ 20 parts, Herba Verbenae 10 ~ 20 parts, Fructus Cnidii 10 ~ 20 parts, Herba Patriniae 10 ~ 20 parts, Radix Arnebiae (Radix Lithospermi) 10 ~ 20 parts, Herba Taraxaci 10 ~ 20 parts, Herba Schizonepetae 10 ~ 20 parts, Fructus Toosendan 10 ~ 20 parts.
3. prevent and treat the men's external wash liquid of balanitis according to claim 1, it is characterized in that, in described men's external wash liquid, the parts by weight of various crude drug are: Herba Portulacae 10 ~ 20 parts, Herba Artemisiae Scopariae 10 ~ 20 parts, Indigo Naturalis 10 ~ 20 parts, Rhizoma Atractylodis 10 ~ 20 parts, Rhizoma Paridis 10 ~ 20 parts, the Radix Stemonae 10 ~ 20 parts, Cortex Phellodendri 10 ~ 20 parts, Radix Sophorae Flavescentis 10 ~ 20 parts, the Fructus Kochiae 10 ~ 20 parts, Cortex Dictamni 10 ~ 15 parts, Herba Senecionis Scandentis 10 ~ 15 parts, Rhizoma Smilacis Glabrae 10 ~ 15 parts, Herba Verbenae 10 ~ 15 parts, Fructus Cnidii 10 ~ 15 parts, Herba Patriniae 10 ~ 15 parts, Radix Arnebiae (Radix Lithospermi) 10 ~ 15 parts, Herba Taraxaci 10 ~ 15 parts, Herba Schizonepetae 10 ~ 15 parts, Fructus Toosendan 10 ~ 15 parts.
CN201510856167.2A 2015-11-29 2015-11-29 Male topical lotion for preventing balanitis and preparation method thereof Pending CN105396006A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105535170A (en) * 2016-01-25 2016-05-04 李秀华 Compound male private part nursing lotion and preparation method thereof
CN112826770A (en) * 2021-01-20 2021-05-25 广州他秘生物科技有限公司 Male care solution and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105535170A (en) * 2016-01-25 2016-05-04 李秀华 Compound male private part nursing lotion and preparation method thereof
CN112826770A (en) * 2021-01-20 2021-05-25 广州他秘生物科技有限公司 Male care solution and preparation method thereof

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Application publication date: 20160316