CN111249163A - Nourishing and repairing freeze-dried powder and preparation method thereof - Google Patents
Nourishing and repairing freeze-dried powder and preparation method thereof Download PDFInfo
- Publication number
- CN111249163A CN111249163A CN202010129650.1A CN202010129650A CN111249163A CN 111249163 A CN111249163 A CN 111249163A CN 202010129650 A CN202010129650 A CN 202010129650A CN 111249163 A CN111249163 A CN 111249163A
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- Prior art keywords
- freeze
- dried powder
- parts
- nourishing
- repairing
- Prior art date
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- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 22
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- WQXNXVUDBPYKBA-YFKPBYRVSA-N ectoine Chemical compound CC1=[NH+][C@H](C([O-])=O)CCN1 WQXNXVUDBPYKBA-YFKPBYRVSA-N 0.000 claims abstract description 15
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- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims abstract description 11
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Landscapes
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- Medicinal Preparation (AREA)
Abstract
The invention discloses a nourishing and repairing freeze-dried powder which comprises a freeze-dried powder part and a solvent part, wherein the freeze-dried powder part is prepared from the following raw materials in parts by weight: 90-95 parts of deionized water, 4-6 parts of mannitol, 0.6-0.12 part of trehalose, 0.1-0.15 part of sodium chloride, 0.15-0.25 part of disodium hydrogen phosphate, 0.05-0.2 part of sodium dihydrogen phosphate, 0.5-1.5 parts of bluecopper peptide, 0.8-1.2 parts of ectoin and 0.02-0.04 part of composite peptide. The nourishing and repairing freeze-dried powder is composed of a freeze-dried powder part and a solvent part, the solvent part is poured into the freeze-dried powder part and is evenly shaken to obtain the nourishing and repairing freeze-dried powder, and the nourishing and repairing freeze-dried powder can help the maintenance and growth of skin collagen and elastin, promote the self-repairing of skin, fade skin fine lines, make the skin compact and tender, and is elastic, healthy and active.
Description
Technical Field
The invention relates to the field of cosmetics, and in particular relates to a nourishing and repairing freeze-dried powder and a preparation method thereof.
Background
The freeze-dried powder is a sterile powder injection which is prepared by freezing a liquid medicine below a eutectic point in a sterile environment by adopting a freeze vacuum drying technology to convert the liquid medicine into a solid state, and then carrying out vacuum pumping to sublimate and dry water. In short, the water in the liquid medicine is pumped out under low temperature environment to change the liquid medicine into solid state and retain the original medicinal effect. The freeze-dried powder has wide application, especially in the field of medicaments.
Along with the improvement of living standard of people, people pay more and more attention to skin maintenance. The skin care cannot be kept away from various cosmetics, and the existing cosmetics are mostly presented in the form of water solution or emulsion, and cannot retain the active ingredients in the formula to the maximum extent. The product adopts an advanced freeze drying technology, retains active ingredients in the formula to the greatest extent, and is particularly added with the active ingredients of the blue copper peptide, the polypeptide and the like, so that the damaged skin is repaired and nourished, fine wrinkles are reduced, the skin is tightened, and the skin elasticity is restored. Meanwhile, different from the traditional freeze-dried powder, the freeze-dried powder and the solvent liquid are merged into a double-cavity combined bottle, the freeze-dried powder and the solvent can be uniformly mixed only by pressing and shaking up, the pollution risk generated in the using process is avoided, and the use of consumers is greatly facilitated.
Disclosure of Invention
The invention aims to provide nourishing and repairing freeze-dried powder and a preparation method thereof.
The invention adopts the following technical scheme for solving the technical problems:
the nourishing and repairing freeze-dried powder comprises a freeze-dried powder part and a solvent part, wherein the freeze-dried powder part is prepared from the following raw materials in parts by weight: 90-95 parts of deionized water, 4-6 parts of mannitol, 0.6-0.12 part of trehalose, 0.1-0.15 part of sodium chloride, 0.15-0.25 part of disodium hydrogen phosphate, 0.05-0.2 part of sodium dihydrogen phosphate, 0.5-1.5 parts of bluecopper peptide, 0.8-1.2 parts of ectoin and 0.02-0.04 part of composite peptide.
As a most preferred scheme, the freeze-dried powder part is prepared from the following raw materials in parts by weight: 91.67 parts of deionized water, 5 parts of mannitol, 0.9 part of trehalose, 0.12 part of sodium chloride, 0.18 part of disodium hydrogen phosphate, 0.1 part of sodium dihydrogen phosphate, 1 part of copper blue peptide, 1 part of ectoin and 0.03 part of mixed peptide.
Preferably, the mixed peptide is composed of two or more of palmitoyl tetrapeptide-7, tripeptide-1, hexapeptide-9, palmitoyl pentapeptide-4, palmitoyl tripeptide-1 and palmitoyl tripeptide-5.
As a preferable scheme, the solvent part is composed of the following raw materials in parts by weight: 95-99 parts of deionized water, 0.03-0.07 part of sodium hyaluronate, 0.04-0.06 part of polyglutamic acid, 0.6-1.5 parts of oat glucan and 0.5-0.8 part of hexanediol.
As a most preferred scheme, the solvent part consists of the following raw materials in parts by weight: 98.3 parts of deionized water, 0.05 part of sodium hyaluronate, 0.05 part of polyglutamic acid, 1 part of oat glucan and 0.6 part of hexanediol.
As a preferred scheme, the preparation method of the freeze-dried powder part comprises the following steps:
s1: weighing raw materials according to a ratio, placing mannitol, trehalose, sodium chloride, disodium hydrogen phosphate, sodium dihydrogen phosphate and deionized water into a reaction kettle, and stirring at the rotating speed of 500-700 rpm for 8-12 min to obtain a mixed solution;
s2: sterilizing the mixed solution at 115-125 ℃ for 25-35 min under high pressure, cooling to 35-45 ℃, adding the blue copper peptide, the ectoin and the mixed peptide, placing the mixture in a reaction kettle, stirring for 6-14 min at the rotation speed of 450-550 rpm, uniformly mixing, and filtering by using a filter membrane to remove insoluble impurities;
s3: filling the filtered mixed solution into an inner cavity of a double-cavity combined bottle, wherein the filling amount is 1-2 ml, putting the filled solution into a vacuum freeze dryer, keeping a vacuum environment, cooling to-45 ℃ to-40 ℃, preserving heat for 4-8 hours, and performing pre-freezing operation; heating to-6 to-4 ℃, preserving the heat for 10 to 15 hours, and freezing; heating to-2 ℃, preserving the heat for 4-8 hours, and carrying out sublimation drying operation; and finally, heating to 40-45 ℃, preserving heat for 4-8 hours, performing desorption drying operation to finish freeze drying, performing plug pressing in a vacuum state, and taking out of the pot to obtain the freeze-dried powder part.
As a preferable scheme, the preparation method of the solvent part comprises the following steps:
s11: weighing the raw materials according to the proportion, putting deionized water, sodium hyaluronate, polyglutamic acid and oat glucan into an emulsifying pot, heating to 80-90 ℃, and uniformly stirring;
s12: and cooling to 40-50 ℃, adding hexanediol, stirring at 600-800 rpm for 5-10 min, filtering and discharging to obtain a solvent solution, and filling the qualified solvent solution into an outer bottle of the double-cavity combination bottle to obtain the solvent part.
Preferably, the stirring speed in the S11 is 650-750 rpm, and the stirring time is 15-25 min.
Preferably, the filtration is performed by using 450-550 mesh gauze.
The invention also provides a preparation method of the nourishing and repairing freeze-dried powder, which comprises the steps of pouring the solvent part into the freeze-dried powder part, and shaking uniformly to obtain the nourishing and repairing freeze-dried powder.
The copper-coated peptides can restore the skin repair capacity, increase the generation of intercellular adhesions of the skin and reduce the skin damage; stimulating the formation of glucose polyamine, increasing the thickness of the skin, reducing the looseness of the skin and compacting the skin; stimulating the formation of collagen and elastin, firming skin and reducing fine lines; the auxiliary antioxidant enzyme SOD has strong and powerful free radical resisting function; promoting blood vessel proliferation, and increasing oxygen supply to skin.
Ectoin has protective, preventive, restorative and regenerative effects, its excellent stability and protection bring visible and long-term anti-aging effects to our skin. Clinical studies have shown that continued ectoin skin condition reduces TEWL (transepidermal water loss), increases hydration, and retains skin water for 7 days without repeated use! Furthermore, ectoin can also calm and soothe irritated and damaged skin. The process of skin regeneration is significantly increased. Due to its excellent anti-inflammatory properties, ectoin is even used for the treatment of atopic dermatitis (neurodermatitis) or allergic skin diseases (OTC medical devices).
Palmitoyl tetrapeptide-7 belongs to palmitoyl polypeptide, and has effects of resisting inflammation, tightening, reducing fine lines, repairing epidermal layer, etc.
Tripeptide-1 belongs to polypeptides and has the effects of promoting keratinocyte proliferation, repairing epidermal layers and the like.
Hexapeptide-9 belongs to polypeptide, and has effects of promoting keratin synthesis, promoting epidermal regeneration, promoting IV type collagen and laminin generation, and strengthening DEJ.
Palmitoyl pentapeptide-4 belongs to palmitoyl polypeptide, is widely used in cosmetics and high-grade products for human body care, and has the effects of promoting the synthesis of collagen, hyaluronic acid, fibronectin and monolignol and the like.
The palmitoyl tripeptide-1 belongs to palmitoyl polypeptides, is widely used in cosmetics and high-grade products for human body care, and has the effects of promoting the synthesis of collagen, hyaluronic acid, fibronectin and monolignol and the like.
The palmitoyl tripeptide-5 belongs to palmitoyl polypeptides, is widely used in cosmetics and high-grade products for human body care, and has the effects of promoting the synthesis of collagen, hyaluronic acid, fibronectin and monolignol and the like.
Sodium hyaluronate is an acidic mucopolysaccharide, has a special water retention effect, has more than 500 times of water carried by hyaluronic molecules, is a substance which is found to have the best moisture retention in nature at present, is an ideal natural moisture retention factor, is a good transdermal absorption promoter, and can play a role in promoting nutrient absorption when being matched with other nutrient components.
Polyglutamic acid is a water-soluble, biodegradable, non-toxic biopolymer substance prepared using microbial fermentation. The molecular weight is more than 70 ten thousand, and the special molecular structure ensures that the cosmetic has extremely strong moisturizing capability, can effectively increase the moisturizing capability of the skin and promote the health of the skin, and is a new-generation biotechnological moisturizing component; has long-lasting anti-wrinkle performance as a whitening agent and has more advantages than other polymer commodities.
The oat glucan has excellent anti-aging effect, can smooth fine wrinkles, improve the skin elasticity and improve the skin texture, has a unique linear chain molecular structure and endows good transdermal absorption performance; promoting the fibroblast to synthesize collagen, promoting wound healing, repairing damaged skin, and providing silky moist and smooth touch feeling to the skin.
The invention has the beneficial effects that: the nourishing and repairing freeze-dried powder is composed of a freeze-dried powder part and a solvent part, the solvent part is poured into the freeze-dried powder part and is evenly shaken to obtain the nourishing and repairing freeze-dried powder, and the nourishing and repairing freeze-dried powder can help the maintenance and growth of skin collagen and elastin, promote the self-repairing of skin, fade skin fine lines, make the skin compact and tender, and is elastic, healthy and active.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are a part of the embodiments of the present invention, but not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
The nourishing and repairing freeze-dried powder comprises a freeze-dried powder part and a solvent part, wherein the freeze-dried powder part is prepared from the following raw materials in parts by weight: 91.67 parts of deionized water, 5 parts of mannitol, 0.9 part of trehalose, 0.12 part of sodium chloride, 0.18 part of disodium hydrogen phosphate, 0.1 part of sodium dihydrogen phosphate, 1 part of copper blue peptide, 1 part of ectoin and 0.03 part of mixed peptide.
The mixed peptide consists of palmitoyl tetrapeptide-7, tripeptide-1, hexapeptide-9, palmitoyl pentapeptide-4, palmitoyl tripeptide-1 and palmitoyl tripeptide-5, wherein the weight ratio of the palmitoyl tetrapeptide-7, the tripeptide-1, the hexapeptide-9, the palmitoyl pentapeptide-4, the palmitoyl tripeptide-1 and the palmitoyl tripeptide-5 is 6: 1:1:1:1:1.
The solvent part comprises the following raw materials in parts by weight: 98.3 parts of deionized water, 0.05 part of sodium hyaluronate, 0.05 part of polyglutamic acid, 1 part of oat glucan and 0.6 part of hexanediol.
The preparation method of the freeze-dried powder part comprises the following steps:
s1: weighing raw materials according to a ratio, placing mannitol, trehalose, sodium chloride, disodium hydrogen phosphate, sodium dihydrogen phosphate and deionized water into a reaction kettle, and stirring at the rotating speed of 600rpm for 10min to obtain a mixed solution;
s2: sterilizing the mixed solution at 121 deg.C under high pressure for 30min, cooling to 40 deg.C, adding blue copper peptide, ectoin and mixed peptide, placing in a reaction kettle, stirring at 500rpm for 10min, mixing, filtering with a filter membrane to remove insoluble impurities;
s3: filling the filtered mixed solution into an inner cavity of a double-cavity combined bottle, wherein the filling amount is 1.5ml, putting the filled solution into a vacuum freeze dryer, keeping a vacuum environment, cooling to-45 ℃ to-40 ℃, preserving heat for 6 hours, and performing pre-freezing operation; heating to-5 ℃, preserving heat for 12h, and performing freezing operation; heating to-0 deg.C, maintaining for 6 hr, and sublimation drying; and finally, heating to 40-45 ℃, preserving heat for 6 hours, carrying out desorption drying operation, completing freeze drying, carrying out plug pressing in a vacuum state, and taking out of the pot to obtain the freeze-dried powder part.
The preparation method of the solvent part comprises the following steps:
s11: weighing raw materials according to a ratio, putting deionized water, sodium hyaluronate, polyglutamic acid and oat glucan into an emulsifying pot, heating to 85 ℃, and uniformly stirring;
s12: cooling to 45 deg.C, adding hexanediol, stirring at 700rpm for 8min, filtering, discharging to obtain solvent solution, and filling the qualified solvent solution into the outer bottle of the double-chamber combination bottle to obtain the solvent fraction.
In the S11, the stirring speed is 700rpm, and the stirring time is 20 min.
The filtration was performed with 500 mesh gauze.
The preparation method of the nourishing and repairing freeze-dried powder comprises the steps of pouring a solvent part into a freeze-dried powder part, and shaking up to obtain the nourishing and repairing freeze-dried powder.
Example 2
Example 2 differs from example 1 in the ratio of the lyophilized powder portion, and the other portions are the same.
The freeze-dried powder part is prepared from the following raw materials in parts by weight: 90 parts of deionized water, 4 parts of mannitol, 0.6 part of trehalose, 0.1 part of sodium chloride, 0.15 part of disodium hydrogen phosphate, 0.05 part of sodium dihydrogen phosphate, 0.5 part of copper blue peptide, 0.8 part of ectoin and 0.02 part of composite peptide.
Example 3
Example 3 differs from example 1 in the ratio of the lyophilized powder portion, and the other portions are the same.
The freeze-dried powder part is prepared from the following raw materials in parts by weight: 95 parts of deionized water, 6 parts of mannitol, 0.12 part of trehalose, 0.15 part of sodium chloride, 0.25 part of disodium hydrogen phosphate, 0.2 part of sodium dihydrogen phosphate, 1.5 parts of copper blue peptide, 1.2 parts of ectoin and 0.04 part of composite peptide.
Example 4
Example 4 differs from example 1 in the ratio of the solvent portion, and is otherwise the same.
The solvent part comprises the following raw materials in parts by weight: 95 parts of deionized water, 0.03 part of sodium hyaluronate, 0.04 part of polyglutamic acid, 0.6 part of oat glucan and 0.5 part of hexanediol.
Example 5
Example 5 differs from example 1 in the ratio of the solvent portion, and is otherwise the same.
The solvent part comprises the following raw materials in parts by weight: 99 parts of deionized water, 0.07 part of sodium hyaluronate, 0.06 part of polyglutamic acid, 1.5 parts of oat glucan and 0.8 part of hexanediol.
Comparative example 1
Comparative example 1 is different from example 1 in that the lyophilized powder of comparative example 1 does not contain the mixed peptide partially, and the rest is the same.
Comparative example 2
Comparative example 2 is example 1 except that the lyophilized powder of comparative example 2 does not contain the bluepatide partially, and the rest is the same.
Comparative example 3
Comparative example 3 is different from example 1 in that the lyophilized powder of comparative example 3 does not contain mixed peptide and blue copperpeptide, and the rest is the same.
Comparative example 4
Comparative example 4 differs from example 1 in that the solvent portion of comparative example 4 does not contain polyglutamic acid, and the other is the same.
To further demonstrate the effect of the present invention, the following test methods were provided:
fine grain shrinkage, skin stretch test.
Testing an instrument: CCD test sensor, skin elasticity tester MPA580, sine stripe projector, and skin rapid three-dimensional imaging system PRIMOS lite.
The skin rapid three-dimensional imaging system PRIMOS lite is a digital optical three-dimensional image analysis instrument developed on the basis of a digital micro-fringe projector. The stripe light with sinusoidal density is projected to the skin or surface of the object under test. Due to the uneven height of the skin or the surface of the object to be measured, the stripe light is bent and deformed, and a CCD camera placed at a specific angle records the change at the same time. By measuring the position change of the stripe light and the grey values of all image points, a digital three-dimensional image of the entire test skin surface or test object can be obtained.
Skin elasticity tester MPA 580: the test principle is based on the principle of suction and stretching, where a negative pressure is generated on the skin surface to be tested to suck the skin into a specific test probe, and the depth of the skin sucked into the test probe is measured by a non-contact optical test system. The test probe includes a transmitter and receiver of light, the ratio of which (the ratio of the transmitted light to the received light) is proportional to the depth of the skin into which it is sucked, and then analyzed by MPA software to determine the elastic properties of the skin.
The test method comprises the following steps: 50 tested volunteers (age 35-55 years) are selected, male and female are basically half, the test part is a whole face, and the test time is 21 days. Volunteers were asked to take the form of a twice-a-day test site using the restorative nourishing lyophilized powders described in examples 1-5 and comparative examples 1-4. Data were obtained by analysis before and after the test, respectively. Uniformly smearing a small amount of test samples on a test part of a tested volunteer, irradiating the test part by using a sine stripe projector after a certain time, collecting three-dimensional image data of the test part by using a CCD (charge coupled device) test sensor, and processing the data by using a skin rapid three-dimensional imaging system PRIMOS lite to obtain an experimental result. Skin fast three-dimensional imaging system PRIMOS lite data processing: the CCD test sensor is used for collecting original three-dimensional image data.
And screening the region with concentrated filter expression lines, and measuring the surface area, volume and depth of the wrinkles. And comparing the image data matched with the same sample, and calculating the wrinkle shrinkage rate by using an Overlay ghost image overlapping test method, wherein the test result is shown in table 1, and the larger the numerical value is, the fewer the fine lines on the skin are. .
Skin elasticity test data processing results: the skin elasticity parameters and curves are automatically obtained, data and personnel detailed data are recorded and integrated, the skin elasticity parameters are calculated, the test result is shown in table 2, and the closer the ratio is to 1, the better the skin elasticity is.
TABLE 1 Fine grain shrinkage test results
As can be seen from table 1, the lyophilized powder of the present invention has good nourishing and repairing effects, wherein example 1 has the best nourishing and repairing effect; as can be seen from comparison of examples 1-3, the ratio of different lyophilized powder portions can affect the nourishing and repairing effect, wherein example 1 is the optimal ratio of lyophilized powder portions; comparing example 1 with examples 4 and 5, it can be known that the ratio of different solvent parts can affect the nourishing and repairing effect, wherein example 1 is the optimal solvent part ratio; comparing example 1 with comparative example 1, it can be known that the mixed peptide can significantly improve the nourishing and repairing effect; comparing example 1 with comparative example 2, it can be known that the blue copper peptide can significantly improve the nourishing and repairing effect; comparing example 1 with comparative example 3, it can be seen that the mixed peptide and the blue copper peptide have a synergistic nourishing and repairing effect in the formulation of the present invention; comparing example 1 with comparative example 4, it can be known that polyglutamic acid can significantly improve the nourishing and repairing effects of the freeze-dried powder of the present invention.
In light of the foregoing description of preferred embodiments according to the invention, it is clear that many changes and modifications can be made by the person skilled in the art without departing from the scope of the invention. The technical scope of the present invention is not limited to the contents of the specification, and must be determined according to the scope of the claims.
Claims (10)
1. The nourishing and repairing freeze-dried powder comprises a freeze-dried powder part and a solvent part, and is characterized in that the freeze-dried powder part is prepared from the following raw materials in parts by weight: 90-95 parts of deionized water, 4-6 parts of mannitol, 0.6-0.12 part of trehalose, 0.1-0.15 part of sodium chloride, 0.15-0.25 part of disodium hydrogen phosphate, 0.05-0.2 part of sodium dihydrogen phosphate, 0.5-1.5 parts of bluecopper peptide, 0.8-1.2 parts of ectoin and 0.02-0.04 part of composite peptide.
2. The nourishing and repairing freeze-dried powder according to claim 1, wherein the freeze-dried powder is partially prepared from the following raw materials in parts by weight: 91.67 parts of deionized water, 5 parts of mannitol, 0.9 part of trehalose, 0.12 part of sodium chloride, 0.18 part of disodium hydrogen phosphate, 0.1 part of sodium dihydrogen phosphate, 1 part of copper blue peptide, 1 part of ectoin and 0.03 part of mixed peptide.
3. A trophozoietic repair freeze-dried powder according to claim 2, characterised in that the mixed peptides consist of palmitoyl tetrapeptide-7, tripeptide-1, hexapeptide-9, palmitoyl pentapeptide-4, palmitoyl tripeptide-1, palmitoyl tripeptide-5.
4. The nourishing and repairing lyophilized powder of claim 1, wherein the solvent part is composed of the following raw materials in parts by weight: 95-99 parts of deionized water, 0.03-0.07 part of sodium hyaluronate, 0.04-0.06 part of polyglutamic acid, 0.6-1.5 parts of oat glucan and 0.5-0.8 part of hexanediol.
5. The nourishing and repairing lyophilized powder of claim 4, wherein the solvent part is composed of the following raw materials in parts by weight: 98.3 parts of deionized water, 0.05 part of sodium hyaluronate, 0.05 part of polyglutamic acid, 1 part of oat glucan and 0.6 part of hexanediol.
6. The nourishing and repairing lyophilized powder of claim 1, wherein the lyophilized powder is prepared by:
s1: weighing raw materials according to a ratio, placing mannitol, trehalose, sodium chloride, disodium hydrogen phosphate, sodium dihydrogen phosphate and deionized water into a reaction kettle, and stirring at the rotating speed of 500-700 rpm for 8-12 min to obtain a mixed solution;
s2: sterilizing the mixed solution at 115-125 ℃ for 25-35 min under high pressure, cooling to 35-45 ℃, adding the blue copper peptide, the ectoin and the mixed peptide, placing the mixture in a reaction kettle, stirring for 6-14 min at the rotation speed of 450-550 rpm, uniformly mixing, and filtering by using a filter membrane to remove insoluble impurities;
s3: filling the filtered mixed solution into an inner cavity of a double-cavity combined bottle, wherein the filling amount is 1-2 ml, putting the filled solution into a vacuum freeze dryer, keeping a vacuum environment, cooling to-45 ℃ to-40 ℃, preserving heat for 4-8 hours, and performing pre-freezing operation; heating to-6 to-4 ℃, preserving the heat for 10 to 15 hours, and freezing; heating to-2 ℃, preserving the heat for 4-8 hours, and carrying out sublimation drying operation; and finally, heating to 40-45 ℃, preserving heat for 4-8 hours, performing desorption drying operation to finish freeze drying, performing plug pressing in a vacuum state, and taking out of the pot to obtain the freeze-dried powder part.
7. The nourishing and repairing lyophilized powder of claim 4, wherein the solvent portion is prepared by the following steps:
s11: weighing the raw materials according to the proportion, putting deionized water, sodium hyaluronate, polyglutamic acid and oat glucan into an emulsifying pot, heating to 80-90 ℃, and uniformly stirring;
s12: and cooling to 40-50 ℃, adding hexanediol, stirring at 600-800 rpm for 5-10 min, filtering and discharging to obtain a solvent solution, and filling the qualified solvent solution into an outer bottle of the double-cavity combination bottle to obtain the solvent part.
8. The nourishing and repairing freeze-dried powder according to claim 7, wherein the stirring speed in S11 is 650-750 rpm, and the stirring time is 15-25 min.
9. The nourishing and repairing lyophilized powder of claim 7, wherein the filtration is performed with 450-550 mesh gauze.
10. The method for preparing the nourishing and repairing freeze-dried powder as claimed in any one of claims 1 to 9, wherein a solvent part is poured into a freeze-dried powder part, and the mixture is shaken up to obtain the nourishing and repairing freeze-dried powder.
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