CN111228423A - Pharmaceutical composition applied to novel rehabilitation and nursing of coronavirus pneumonia - Google Patents
Pharmaceutical composition applied to novel rehabilitation and nursing of coronavirus pneumonia Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
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- A61K36/88—Liliopsida (monocotyledons)
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
A medicine composition applied to rehabilitation and nursing of novel coronavirus pneumonia comprises the following raw materials in parts by weight: 8-15 parts of lily, 8-15 parts of poria cocos, 8-15 parts of coix seeds, 8-15 parts of rhizoma polygonati, 3-8 parts of allium macrostemon, 3-8 parts of momordica grosvenori, 3-8 parts of dark plum, 3-8 parts of kudzu roots and 3-8 parts of perilla leaves, and when the preparation is a decoction, the preparation of the decoction comprises the following steps: mixing all the raw materials according to a ratio of liquid to solid of 1: (15-20), soaking until the water absorption of the raw materials is complete, boiling with strong fire, decocting for 15-20 min, turning to small fire, continuously decocting for 15-20 min, and filtering to obtain filtrate. The traditional Chinese medicine composition is applied to rehabilitation of patients infected with new coronavirus and cured, and can shorten the rehabilitation period and effectively improve the rehabilitation.
Description
Technical Field
The invention relates to a traditional Chinese medicine composition, and in particular relates to a medicine composition applied to rehabilitation and nursing of novel coronavirus pneumonia.
Background
The coronavirus belongs to a single strand positive strand RNA virus, 6 kinds of previously known coronavirus infecting people are HCoV-229E, HCoV-OC43, HCoV-NL63, HCoV-HKU1, SARSr-CoV and MERSR-CoV, the novel coronavirus pneumonia is acute infectious pneumonia, the pathogen of the novel coronavirus is 2019 novel coronavirus belonging to β which is not found in human, the English name is COVID-19, the initial symptoms of infected patients are mostly fever, weakness and dry cough, severe manifestations such as dyspnea gradually appear, part of patients have acute respiratory distress syndrome and sepsis shock, and even die, at present, isolation treatment and symptomatic support treatment are mainly used for severe patients, such as severe patients adopt respiratory support, circulatory support, renal failure and renal replacement treatment, rehabilitative patient plasma treatment, blood purification treatment and combination of antiviral and antibacterial drugs, however, the patients who have a great initial cure cost, the yin-yang organism is in a partial cure state, the body is in a partial yin-nourishing state, the rehabilitation period is still in a recovery period, and the novel traditional Chinese medicine can be developed and can be used for effectively detecting and is used for treating the sequelae after the acute respiratory distress and the rehabilitation period.
Disclosure of Invention
The invention aims to solve the technical problem of providing a pharmaceutical composition applied to rehabilitation and nursing of novel coronavirus pneumonia and a preparation method thereof, and aims to solve the problems that patients infected with the novel coronavirus are long in later-period rehabilitation period and poor in rehabilitation effect.
The technical problem solved by the invention is realized by adopting the following technical scheme:
a medicine composition applied to rehabilitation and nursing of novel coronavirus pneumonia comprises the following raw materials in parts by weight: 8-15 parts of lily, 8-15 parts of poria cocos, 8-15 parts of semen coicis, 8-15 parts of rhizoma polygonati, 3-8 parts of allium macrostemon, 3-8 parts of momordica grosvenori, 3-8 parts of dark plum, 3-8 parts of radix puerariae and 3-8 parts of perilla leaf.
Further, the feed comprises the following raw materials in parts by weight: 10-12 parts of lily, 10-12 parts of poria cocos, 10-12 parts of coix seeds, 10-12 parts of rhizoma polygonati, 5-8 parts of allium macrostemon, 5-8 parts of momordica grosvenori, 5-8 parts of dark plum fruits, 5-8 parts of kudzu roots and 5-8 parts of perilla leaves.
Preferably, the mass ratio of the lily to the tuckahoe is 1: 1.
Preferably, the mass ratio of the sealwort to the coix seed is 1: 1.
Preferably, the mass ratio of the longstamen onion bulb, the grosvener siraitia, the dark plum fruit and the kudzuvine root is 1:1:1:1
Further, the pharmaceutical composition is prepared from the following raw materials in parts by weight: 10 parts of lily, 10 parts of tuckahoe, 10 parts of semen coicis, 10 parts of rhizoma polygonati, 5 parts of allium macrostemon, 5 parts of momordica grosvenori, 5 parts of dark plum, 5 parts of kudzu root and 5 parts of perilla leaf.
Furthermore, the pharmaceutical composition is added with pharmaceutically conventional auxiliary materials to prepare clinically acceptable dosage forms.
Further, the dosage form is a decoction or a powder.
Further, the preparation of the water decoction comprises the following steps: mixing all the raw materials according to a ratio of liquid to solid of 1: (15-20), soaking until the water absorption of the raw materials is complete, boiling with strong fire, decocting for 15-20 min, turning to small fire, continuously decocting for 15-20 min, and filtering to obtain filtrate.
The protective pharmaceutical composition is applied to preparing the medicines with the effects of strengthening spleen, tonifying lung, nourishing yin and clearing heat.
Further protects the application of the pharmaceutical composition in preparing the medicine for rehabilitation and recuperation of pneumonia diseases.
Further, the pneumonia includes, but is not limited to, pneumonia caused by infection with the novel coronavirus 2019-nCoV.
The traditional Chinese medicine composition consists of nine medicines of lily, tuckahoe, coix seed, rhizoma polygonati, allium macrostemon, fructus momordicae, dark plum, radix puerariae and perilla leaf.
The body which is infected with the novel coronavirus and is primarily cured is quite weak, and diseases are caused by exorbitant lung defense and muscle striae and internal accumulation of lung and spleen and stomach due to incomplete epidemic toxin and excessive dampness, but the spleen and stomach are regarded as ' acquired root ' and have ' internal injury to the spleen and stomach and ' generation of diseases ' in Chinese medicine, the spleen is a main organ for transporting and transforming moisture, the spleen can ' transport and transform food and water dampness ' in Chinese medicine, meaning that the spleen has digestion function and also bears the important responsibility for ' transforming moisture ', the spleen deficiency is easy to be subjected to heavy moisture, if not conditioned in time, phenomena of anorexia, abdominal distension and inappetence easily occur, the smooth progress of rehabilitation is greatly influenced, in addition, the damage to the lung, spleen and stomach inevitably affects qi, blood and body fluid, so that yin and yang imbalance, channel and collateral functional disorder, qi, body fluid metabolism disorder, viscera structure and other injuries in different degrees are gradually recovered, in addition, it is very critical that the body is treated by various traumatic treatments, so that the mood is high and the emotional distress, internal injury and stagnation of liver qi are not good for the recuperation and quick recovery of the body.
In the traditional Chinese medicine composition, the lily bulb has the effects of nourishing yin, moistening the lung, clearing away the heart-fire and soothing the nerves; tuckahoe has the effects of promoting diuresis and eliminating dampness, strengthening spleen and calming heart; both of them are monarch drugs with the actions of nourishing yin, strengthening spleen, moistening lung and calming heart. Rhizoma Polygonati is used as adjuvant for invigorating qi, nourishing yin, invigorating spleen and moistening lung; coix seed has the effects of promoting diuresis, eliminating dampness, invigorating spleen and stopping diarrhea; is used as a ministerial drug. The macrostem onion activates yang and dissipates stagnation, and promotes qi circulation and removes stagnation; fructus momordicae clears heat and moistens lung, relieves sore throat and makes sound; dark plum astringes lung and promotes production of body fluid; radix Puerariae has effects of expelling pathogenic factors from muscles, relieving fever, promoting fluid production, quenching thirst, invigorating yang, and dredging collaterals; the four ingredients are adjuvant drugs; perilla leaf, folium Perillae, Perilla. The nine medicines are medicines with the same source of medicine and food, are properly matched and complement each other, have the effects of nourishing yin and clearing heat, tonifying spleen and benefiting lung, and calming heart and tranquilizing mind, are particularly suitable for the later-stage rehabilitation and conditioning of new crown pneumonia, are also suitable for the conditioning of patients with chronic cough and early recovery and the conditioning of the constitution of people with spleen deficiency and lung deficiency, and can also be used for the throat maintenance of people with excessive throat for a long time, the conditioning of patients with depression, chronic illness and poor mood and the like.
Has the advantages that: the pharmaceutical composition applied to the rehabilitation and nursing of the novel coronavirus pneumonia is prepared by the synergistic effect of multiple components, has low toxic and side effects, multiple active components, multiple action targets and rich resources, can play the roles of nourishing yin, clearing heat, strengthening spleen, tonifying lung, calming heart and tranquilizing mind, and enables qi and blood of a human body to be smooth.
Detailed Description
In order to make the technical means, the creation features, the achievement purposes and the effects of the invention easy to understand, the invention is further described with the specific embodiments.
Example 1
The pharmaceutical composition applied to rehabilitation and nursing of the novel coronavirus pneumonia comprises the following raw materials in parts by weight: 10g of lily, 10g of tuckahoe, 10g of coix seed, 10g of rhizoma polygonati, 5g of allium macrostemon, 5g of momordica grosvenori, 5g of dark plum, 5g of kudzu root and 5g of perilla leaf.
When the traditional Chinese medicine composition is applied to rehabilitation and nursing of novel coronavirus pneumonia, the decoction is adopted, and the taking method comprises the following steps: one dose is taken twice a day, and the tea is drunk instead of tea.
The preparation method of the water decoction comprises the following steps: mixing all the raw materials, adding 1200ml of water, soaking until the water absorption of the raw materials is complete, boiling with strong fire, decocting for 15min, turning to slow fire, decocting for 15min, and filtering to obtain filtrate.
Note that: patients with cough due to cold do not take the medicine, patients with cough due to wind-cold do not take the medicine, children reduce the dosage, pregnant women take the medicine with caution, and patients with diabetes, gout, hypertension and hyperlipidemia can take the medicine.
Example 2
The pharmaceutical composition applied to rehabilitation and nursing of the novel coronavirus pneumonia comprises the following raw materials in parts by weight: 8g of lily, 8g of tuckahoe, 8g of coix seed, 8g of rhizoma polygonati, 3g of allium macrostemon, 3g of momordica grosvenori, 3g of dark plum, 3g of kudzu root and 3g of perilla leaf.
When the traditional Chinese medicine composition is applied to rehabilitation and nursing of novel coronavirus pneumonia, the decoction is adopted, and the taking method comprises the following steps: one dose is taken twice a day, and the tea is drunk instead of tea.
The preparation method of the water decoction comprises the following steps: mixing all the raw materials, adding 1200ml of water, soaking until the water absorption of the raw materials is complete, boiling with strong fire, decocting for 15min, turning to slow fire, decocting for 15min, and filtering to obtain filtrate.
Note that: patients with cough due to cold do not take the medicine, patients with cough due to wind-cold do not take the medicine, children reduce the dosage, pregnant women take the medicine with caution, and patients with diabetes, gout, hypertension and hyperlipidemia can take the medicine.
Example 3
The pharmaceutical composition applied to rehabilitation and nursing of the novel coronavirus pneumonia comprises the following raw materials in parts by weight: 15g of lily, 15g of poria cocos, 15g of coix seeds, 15g of rhizoma polygonati, 8g of allium macrostemon, 8g of momordica grosvenori, 8g of dark plum, 8g of kudzu root and 8g of perilla leaves.
When the traditional Chinese medicine composition is applied to rehabilitation and nursing of novel coronavirus pneumonia, the decoction is adopted, and the taking method comprises the following steps: one dose is taken twice a day, and the tea is drunk instead of tea.
The preparation method of the water decoction comprises the following steps: mixing all the raw materials, adding 1200ml of water, soaking until the water absorption of the raw materials is complete, boiling with strong fire, decocting for 15min, turning to slow fire, decocting for 15min, and filtering to obtain filtrate.
Note that: patients with cough due to cold do not take the medicine, patients with cough due to wind-cold do not take the medicine, children reduce the dosage, pregnant women take the medicine with caution, and patients with diabetes, gout, hypertension and hyperlipidemia can take the medicine.
Example 4
The pharmaceutical composition applied to rehabilitation and nursing of the novel coronavirus pneumonia comprises the following raw materials in parts by weight: 12g of lily, 12g of tuckahoe, 12g of coix seed, 12g of rhizoma polygonati, 8g of allium macrostemon, 8g of momordica grosvenori, 8g of dark plum, 8g of kudzu root and 8g of perilla leaf.
When the traditional Chinese medicine composition is applied to rehabilitation and nursing of the novel coronavirus pneumonia, the decoction is adopted, and the taking method comprises the following steps: one dose is taken twice a day, and the tea is drunk instead of tea.
The preparation method of the water decoction comprises the following steps: mixing all the raw materials, adding 1200ml of water, soaking until the water absorption of the raw materials is complete, boiling with strong fire, decocting for 20min, turning to slow fire, decocting for 20min, and filtering to obtain filtrate.
Note that: patients with cough due to cold do not take the medicine, patients with cough due to wind-cold do not take the medicine, children reduce the dosage, pregnant women take the medicine with caution, and patients with diabetes, gout, hypertension and hyperlipidemia can take the medicine.
Comparative example 1
The pharmaceutical composition applied to rehabilitation and nursing of the novel coronavirus pneumonia comprises the following raw materials in parts by weight: 16g of lily, 16g of tuckahoe, 16g of coix seed, 16g of rhizoma polygonati, 9g of allium macrostemon, 9g of momordica grosvenori, 9g of dark plum, 9g of kudzu root and 9g of perilla leaf.
When the traditional Chinese medicine composition is applied to rehabilitation and nursing of the novel coronavirus pneumonia, the decoction is adopted, and the taking method comprises the following steps: one dose is taken twice a day, and the tea is drunk instead of tea.
The preparation method of the water decoction comprises the following steps: mixing all the raw materials, adding 1200ml of water, soaking until the water absorption of the raw materials is complete, boiling with strong fire, decocting for 15min, turning to slow fire, decocting for 15min, and filtering to obtain filtrate.
Comparative example 2
The pharmaceutical composition applied to rehabilitation and nursing of the novel coronavirus pneumonia comprises the following raw materials in parts by weight: 9g of lily, 16g of coix seeds, 16g of rhizoma polygonati, 4g of allium macrostemon, 4g of momordica grosvenori, 4g of dark plum, 5g of radix puerariae and 8g of perilla leaves.
When the traditional Chinese medicine composition is applied to rehabilitation and nursing of the novel coronavirus pneumonia, the decoction is adopted, and the taking method comprises the following steps: one dose is taken twice a day, and the tea is drunk instead of tea.
The preparation method of the water decoction comprises the following steps: mixing all the raw materials, adding 1200ml of water, soaking until the water absorption of the raw materials is complete, boiling with strong fire, decocting for 15min, turning to slow fire, decocting for 15min, and filtering to obtain filtrate.
Blank control example
Does not adopt any traditional Chinese medicine composition and preparation, and enables the patient to recover by himself.
After the experiment, compared with a blank control example, the traditional Chinese medicine composition of the embodiment 1 has the shortest period and the best rehabilitation effect, the traditional Chinese medicine compositions of the embodiments 2 to 4 have the next effect after application but are greatly superior to the blank control group, the comparison example 1 adopts the same formula, the formula proportion is beyond the protection range of the invention, one ministerial drug in the embodiment 2 is omitted, and the improvement effect is not obvious compared with the blank control example after the experiment, so that the composition of the formula raw materials and the proportion and the synergistic effect among the raw material components are particularly important.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (9)
1. A pharmaceutical composition applied to rehabilitation and nursing of novel coronavirus pneumonia is characterized by comprising the following raw materials in parts by weight: 8-15 parts of lily, 8-15 parts of poria cocos, 8-15 parts of semen coicis, 8-15 parts of rhizoma polygonati, 3-8 parts of allium macrostemon, 3-8 parts of momordica grosvenori, 3-8 parts of dark plum, 3-8 parts of radix puerariae and 3-8 parts of perilla leaf.
2. The pharmaceutical composition applied to rehabilitation and nursing of the novel coronavirus pneumonia according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 10-12 parts of lily, 10-12 parts of poria cocos, 10-12 parts of coix seeds, 10-12 parts of rhizoma polygonati, 5-8 parts of allium macrostemon, 5-8 parts of momordica grosvenori, 5-8 parts of dark plum fruits, 5-8 parts of kudzu roots and 5-8 parts of perilla leaves.
3. The pharmaceutical composition for rehabilitation and nursing of novel coronavirus pneumonia according to claim 1, wherein the important composition is prepared from the following raw materials in parts by weight: 10 parts of lily, 10 parts of tuckahoe, 10 parts of semen coicis, 10 parts of rhizoma polygonati, 5 parts of allium macrostemon, 5 parts of momordica grosvenori, 5 parts of dark plum, 5 parts of kudzu root and 5 parts of perilla leaf.
4. The pharmaceutical composition applied to rehabilitation and maintenance of the novel coronavirus pneumonia according to any one of claims 1 to 3, wherein the pharmaceutical composition is prepared into clinically acceptable dosage forms by adding pharmaceutically conventional auxiliary materials.
5. The pharmaceutical composition for rehabilitation and maintenance of novel coronavirus pneumonia according to claim 4, wherein the dosage form is water decoction or powder.
6. The pharmaceutical composition for rehabilitation and nursing of novel coronavirus pneumonia according to claim 5, wherein the preparation of the water decoction comprises the following steps: mixing all the raw materials according to a ratio of liquid to solid of 1: (15-20), soaking until the water absorption of the raw materials is complete, boiling with strong fire, decocting for 15-20 min, turning to small fire, continuously decocting for 15-20 min, and filtering to obtain filtrate.
7. The use of the pharmaceutical composition of claim 6 in the preparation of a medicament having the effects of invigorating spleen, benefiting lung, nourishing yin, and clearing heat.
8. The use of the pharmaceutical composition according to claim 6 in the preparation of a medicament for rehabilitation and maintenance of pulmonary inflammatory diseases.
9. The use according to claim 8, wherein the pneumonia includes, but is not limited to, pneumonia caused by infection with a novel coronavirus 2019-nCoV.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010253504.XA CN111228423A (en) | 2020-04-02 | 2020-04-02 | Pharmaceutical composition applied to novel rehabilitation and nursing of coronavirus pneumonia |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202010253504.XA CN111228423A (en) | 2020-04-02 | 2020-04-02 | Pharmaceutical composition applied to novel rehabilitation and nursing of coronavirus pneumonia |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107029146A (en) * | 2017-05-03 | 2017-08-11 | 胡德升 | A kind of clearing lung and eliminating phlegm air making-up and spleen enlivening supports Chinese medicine composition of lung and preparation method thereof |
| CN109700968A (en) * | 2019-01-23 | 2019-05-03 | 广东元之馨生物科技有限公司 | It is a kind of with boosting qi and nourishing yin, the Chinese medicine composition of anti-fatigue effect and preparation method thereof |
| CN110870402A (en) * | 2020-02-06 | 2020-03-06 | 葛又文 | Prescription for treating pneumonia infected by novel coronavirus and application thereof |
-
2020
- 2020-04-02 CN CN202010253504.XA patent/CN111228423A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107029146A (en) * | 2017-05-03 | 2017-08-11 | 胡德升 | A kind of clearing lung and eliminating phlegm air making-up and spleen enlivening supports Chinese medicine composition of lung and preparation method thereof |
| CN109700968A (en) * | 2019-01-23 | 2019-05-03 | 广东元之馨生物科技有限公司 | It is a kind of with boosting qi and nourishing yin, the Chinese medicine composition of anti-fatigue effect and preparation method thereof |
| CN110870402A (en) * | 2020-02-06 | 2020-03-06 | 葛又文 | Prescription for treating pneumonia infected by novel coronavirus and application thereof |
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