A kind of Chinese medicine composition for the treatment of cholinergic urticaria
Technical field
The present invention relates to the medicine that urticaria is treated in a kind of smelting, the Chinese medicine composition of cholinergic urticaria is treated in especially a kind of smelting.
Background technology
Cholinergic urticaria is heated when human body, psychentonia, take in food or the beverage of heat, or body temperature slightly increases after motion, the blood flow of the gain of heat stimulates brain thermotaxic centre, and excited cholinergy is neural, and discharge acetylcholine, if irritated to this chemical substance of acetylcholine, can occur anaphylaxis, the symptom that this allergy causes is referred to as choline motility urticaria by people.This anaphylactoid reaction, except without erythra, only has outside the acute gargalesthesia of twinge, also can occur 2 red millimeter welts at trunk and limbs near-end skin, and this welt speed is next fast goes, and leaves no trace.Whole process be several months to the several years not etc.Current doctor trained in Western medicine there is no specific short to cholinergic urticaria, and many Bian antihistamine drug for oral administration, corticosteroids medicine suppress the symptom of cholinergic urticaria, separately embrocate affected part, in order to alleviate disease by Xian's agent, Emulsion, mud cream, ointment etc.Above-mentioned treatment can only be take stopgap measures, and do not effect a permanent cure, patient often presents recurrent exerbation.In recent years, people's research traditional Chinese medicine composition for treating cholinergic urticaria is had, as Chinese patent CN103393802 discloses the oral medicine of following traditional Chinese medicines component and weight portion; Herba Ephedrae 6-9, Radix Salviae Miltiorrhizae 6-9, Radix Sophorae Flavescentis 6-9, Fructus Cnidii 6-9, Radix Saposhnikoviae 6-9, Cortex Dictamni 3-5, Fructus Kochiae 3-5, Herba Lysimachiae 3-5, Herba Lysimachiae 3-5, Periostracum Cicadae 3-5, fry flying worm 3-5, Radix Gentianae Macrophyllae 3-5, Spina Gleditsiae 3-5, Flos Lonicerae 2-4, Fructus Forsythiae 2-4, Herba Portulacae 2-4, Fructus Atriplicis Sibiricae 2-4, leaf of Semen Juglandis 2-4, Radix Glycyrrhizae 2-4.Except above-mentioned oral medicine, still need with following component and weight fraction composition Chinese medicine lotion for external use embrocate affected part; Linum 6-9, Radix Rehmanniae 6-9, Fructus Gardeniae (parched to brown) 6-9 , Herba Siegesbeckiae 6-9, Radix Arnebiae (Radix Lithospermi) 2-4, Herba Menthae 2-4, Flos Chrysanthemi Indici 2-4, Herba Lycopi 2-4, comb Folium Cannabis 2-4, Folium Isatidis 2-4, Oleum sesami 5-10.Above-mentioned Chinese medicine composition not only formula is complicated, still needs to take orally to start at the same time with external, and therapeutic effect still can not be satisfactory.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art, a kind for the treatment of both the principal and secondary aspects of a disease is provided, the Chinese medicine composition of the treatment cholinergic urticaria that curative effect is high.Object of the present invention is realized by following technical proposals: a kind of Chinese medicine composition for the treatment of cholinergic urticaria, by following component and weight portion formulated: Herba Schizonepetae 5-12, Radix Saposhnikoviae 5-12, Periostracum Cicadae 3-10, Cortex Phellodendri 5-12, Fructus Forsythiae 5-15, Gypsum Fibrosum 10-40, Radix Sophorae Flavescentis 5-15, Cortex Dictamni 5-15, Rhizoma Cimicifugae 3-10, Radix Scutellariae 5-12, Radix Rehmanniae 5-20, Cortex Moutan 5-15, Radix Glycyrrhizae 3-8, above-mentioned each component by Chinese medicine preparation conventional method make decoction, electuary, pill or oral capsule any one.
The present invention mainly utilizes traditional Chinese medicine theoretical direction of science, through to concentrate on studies for many years and clinical practice obtains.Heat-clearing and toxic substances removing in the main centralized optimization component of the present invention, dispelling wind for relieving itching function, in order to the bad clinical symptoms of symptomatic treatment cholinergic urticaria, and by the coordinative role in each component medicine, accelerate measles and thoroughly send out, declare loose rash, endogenous wind stopping relieving convulsion, heat clearing and damp drying, YIN nourishing and the production of body fluid promoting, balanced human's environment, especially reduces nuisance in blood, thus make the toxin in blood discharge body surface with antiperspirant, fundamentally treat this disease.The compatibility of each component of the present invention is rigorous proper, reasonable recipe, effect of each component medicine is: if Herba Schizonepetae, windproof garment expelling pathogenic wind from the body surface function, thoroughly send out not smooth for measles, energy dispelling wind for relieving itching, the loose rash of a surname, Periostracum Cicadae is dispelling wind warm mainly, rash, endogenous wind stopping relieving convulsion function, above three medicines can give full play to adjustment organismic internal environment function, coordinate the five internal organs, in the present invention as monarch drug.Radix Scutellariae heat clearing and damp drying, eliminating fire and detoxication, Fructus Forsythiae heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, the clear part of the body cavity above the diaphragm housing the heart and lungs heat of two medicines, Cortex Phellodendri is heat clearing and damp drying mainly, eliminating fire and detoxication, reducing the asthenic fever, and rash delivered by Rhizoma Cimicifugae, heat-clearing and toxic substances removing, ascending up spleen-Qi and Yang, and above-mentioned four medicines all have the merit of removing toxic substances, as ministerial drug.Cortex Dictamni heat-clearing and toxic substances removing, removing damp to relieve itching, eliminating fire and detoxication, Gypsum Fibrosum clearing away heat-fire, relieving restlessness only exhausts, Radix Sophorae Flavescentis heat clearing and damp drying, wind dispelling insecticide, diuresis, upper three components are as adjuvant drug, Radix Rehmanniae clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, Cortex Moutan clearing away heat and cooling blood, promoting blood circulation to remove blood stasis (is controlled wind and is first controlled blood, blood wind is from going out) for making medicine, Radix Glycyrrhizae invigorating the spleen and replenishing QI, nourishing the lung to arrest cough, relieving spasm to stop pain, relax the property of medicine, guide above-mentioned all medicines to enter blood and the five internal organs, thus ensure medical effect of the present invention.
The present invention is through clinical application for many years, and effect is very good, and cure rate reaches 89%, and effective percentage reaches 99%, refers to table 1.
Note: above-mentioned treatment is used as curative with embodiments of the invention 1 electuary.
The present invention treats case and all determines according to cholinergic urticaria diagnosis index.
Described recovery from illness refers to that cholinergic urticaria symptom all disappears, without recurrence in one month.
Described effectively refers to that cholinergic urticaria symptom obviously alleviates or disappears, but has recurrence in one month.
Described invalid finger cholinergic urticaria symptom without obviously alleviating, or has twice recurrence in one month.
Using method of the present invention: electuary every day three times, each 1 bag, decoction every day three times, each 30 milliliters, pill every day three times, each 20 grams.
Detailed description of the invention
Embodiment 1, a kind of Chinese medicine composition electuary for the treatment of cholinergic urticaria, get the raw materials ready by following component and weight portion:
Herba Schizonepetae 5Kg, Radix Saposhnikoviae 12 Kg, Periostracum Cicadae 8 Kg, Cortex Phellodendri 5 Kg, Fructus Forsythiae 15 Kg, Gypsum Fibrosum 10 Kg, Radix Sophorae Flavescentis 10 Kg, Cortex Dictamni 15 Kg, Rhizoma Cimicifugae 3 Kg, Radix Scutellariae 10 Kg, the Radix Rehmanniae 20 Kg, Cortex Moutan 5 Kg, Radix Glycyrrhizae 8 Kg, production method, follows these steps to carry out:
1, each component is accurately taken for subsequent use;
2, add clean clean water by the 1-2 times amount of Chinese medicine each component total amount, be placed in after decoction pot mixes with Chinese medicinal components and decoct into decoction;
3, concentrated; After filtering residue, decoction is concentrated into the thick paste of 1/4 weight of former dose;
4, sugaring powder, pulverized 40-60 mesh sieve by the white sugar of cleaning in time after about 60 DEG C dryings, made dry Icing Sugar;
5, granule processed, gets thick paste 2 weight portion and adds Icing Sugar 2 weight portion and be placed in container, stirs into moisture state and crosses 10-12 order and to granulate sieve, make granule, and certain Icing Sugar also can with dextrin or starch in replace;
6, dry, packaging after being dried at 40-70 DEG C by the above-mentioned granule made, every bag is 16 grams.
Embodiment 2, a kind of Chinese medicine composition decoction for the treatment of cholinergic urticaria, get the raw materials ready by following component and weight portion:
Herba Schizonepetae 12Kg, Radix Saposhnikoviae 5 Kg, Periostracum Cicadae 3 Kg, Cortex Phellodendri 10 Kg, Fructus Forsythiae 5 Kg, Gypsum Fibrosum 40 Kg, Radix Sophorae Flavescentis 15 Kg, Cortex Dictamni 5 Kg, Rhizoma Cimicifugae 10 Kg, Radix Scutellariae 12 Kg, the Radix Rehmanniae 5 Kg, Cortex Moutan 15 Kg, Radix Glycyrrhizae 3 Kg, production method, follows these steps to carry out:
1, each component is accurately taken for subsequent use;
2, add clean clean water by the 1-2 times amount of Chinese medicine each component total amount, be placed in after decoction pot mixes with Chinese medicinal components and decoct into decoction;
3, concentrated; After filtering residue, decoction is concentrated into the thick soup of 1/3 weight of former dose, subpackage, is advisable with every bottle or a bag 30ml.
Embodiment 3, a kind of Chinese medicine composition pill for the treatment of cholinergic urticaria, get the raw materials ready by following component and weight portion:
Herba Schizonepetae 8Kg, Radix Saposhnikoviae 8 Kg, Periostracum Cicadae 10 Kg, Cortex Phellodendri 12Kg, Fructus Forsythiae 10 Kg, Gypsum Fibrosum 15 Kg, Radix Sophorae Flavescentis 5 Kg, Cortex Dictamni 10Kg, Rhizoma Cimicifugae 8 Kg, Radix Scutellariae 5Kg, the Radix Rehmanniae 15 Kg, Cortex Moutan 10 Kg, Radix Glycyrrhizae 5 Kg, production method, medicine pill producer legal system routinely or pill.