CN111228172A - High-efficiency hair loss prevention and hair growth composition - Google Patents
High-efficiency hair loss prevention and hair growth composition Download PDFInfo
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- CN111228172A CN111228172A CN202010045232.4A CN202010045232A CN111228172A CN 111228172 A CN111228172 A CN 111228172A CN 202010045232 A CN202010045232 A CN 202010045232A CN 111228172 A CN111228172 A CN 111228172A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/606—Nucleosides; Nucleotides; Nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
The invention discloses a high-efficiency hair loss prevention and hair growth composition, which comprises water, a high-activity factor for hair loss prevention and hair growth, an antioxidant anti-inflammatory active factor and a freshener, wherein the content of each component is as follows: the balance of water, 0.1 to 10 percent of high active factor for preventing hair loss and growing hair, 0.1 to 5 percent of antioxidant and anti-inflammatory active factor and 0.01 to 40 percent of freshener. Through the mode, the efficient anti-hair loss and hair growth composition can prevent and improve the condition of hair loss, keep the cortex sanitary, breathable and non-greasy, make the head more comfortable and healthy, converge excessively hypertrophic sebaceous glands, reduce sebum secretion and promote blood circulation, has the effects of cleaning and stimulating fallen hair pores, activates hair follicles to promote hair regrowth, can be further used as a composition in the formulas of cosmetics, skin care and personal care, and has the advantages of strong stability, small side effect, no irritation and wide application.
Description
Technical Field
The invention relates to the technical field of daily chemical compositions, in particular to a high-efficiency hair loss prevention and hair growth composition.
Background
Generally, there are about 100,000 hairs of the scalp, and healthy scalp may continuously lose hairs and new hairs may replace them. The hair growth has the following series of cycles: growth phase, withdrawal phase, resting phase, then return to growth phase. The normal hair loss is the hair in the catagen and telogen phases, and the normal amount of hair can be maintained because the hair entering the catagen phase and the hair newly entering the anagen phase are constantly in dynamic balance.
With the acceleration of the pace of life nowadays and the enhancement of diet, pollution and pressure, the hair can be lost due to frequent staying up all night, excessive exercise, malnutrition, improper hair care, changes of body hormones and the like. If the amount of hair is increased by the deep structures acting on the roots during the growing period, the hair can be continuously healthily increased by injecting new vigor to the roots.
Disclosure of Invention
The invention mainly solves the technical problem of providing the high-efficiency hair loss prevention and hair growth composition, which has the effects of preventing and improving hair loss, keeping cortex sanitary, breathable and non-greasy, has the effects of cleaning and stimulating fallen hair pores, activates hair follicles, promotes hair regrowth, and has small side effect and no irritation.
In order to solve the technical problems, the invention adopts a technical scheme that: the high-efficiency hair loss prevention and growth promotion composition comprises water, a high-activity factor for hair loss prevention and growth promotion, an antioxidant anti-inflammatory active factor and a freshener, and the high-efficiency hair loss prevention and growth promotion composition comprises the following components in percentage by weight: the balance of water, 0.1 to 10 percent of high active factor for preventing hair loss and growing hair, 0.1 to 5 percent of antioxidant and anti-inflammatory active factor and 0.01 to 40 percent of freshener.
In a preferred embodiment of the invention, the high-efficiency hair loss prevention and growth promotion composition consists of water, a hair loss prevention and growth promotion high-activity factor, an antioxidant anti-inflammatory activity factor and a cooling agent, and the contents of the components of the high-efficiency hair loss prevention and growth promotion composition are as follows: the balance of water, 0.1 to 10 percent of high active factor for preventing hair loss and growing hair, 0.1 to 5 percent of antioxidant and anti-inflammatory active factor and 0.01 to 40 percent of freshener.
In a preferred embodiment of the invention, the anti-alopecia and hair growth promoting high activity factor is one or more of diaminopyrimidine oxide, adenosine, caffeine and nicotinamide.
In a preferred embodiment of the invention, the source of diaminopyrimidine oxide is synthetically derived; the caffeine is obtained from plants; the source of nicotinamide is synthetically derived.
In a preferred embodiment of the invention, the antioxidant anti-inflammatory active factor is one or more of vitamin E, resveratrol and centella asiatica extract.
In a preferred embodiment of the invention, the source of vitamin E is synthetically derived; the source of the resveratrol is obtained by biological fermentation; the centella asiatica extract is obtained by biological extraction.
In a preferred embodiment of the invention, the cooling agent is one or a mixture of alcohol, menthol and borneol.
In a preferred embodiment of the invention, the source of the alcohol is obtained by fermentation of plants; the source of the menthol is obtained by plant extraction; the source of the borneol is obtained by extracting plants.
In a preferred embodiment of the invention, the high-efficiency hair loss preventing and growing composition comprises water, diaminopyrimidine oxide, adenosine, caffeine, nicotinamide, vitamin E, resveratrol, centella asiatica extract, alcohol, menthol and borneol, and the contents of the components of the high-efficiency hair loss preventing and growing composition are as follows: the composition comprises, by mass, the balance of water, 0.2-1.5% of diaminopyrimidine oxide, 0.3-1% of adenosine, 0.2-0.5% of caffeine, 3-6% of nicotinamide, 0.2-0.5% of vitamin E, 0.4-1% of resveratrol, 0.4-1% of centella asiatica extract, 15-35% of alcohol, 0.04-0.1% of menthol and 0.1-0.2% of borneol.
In a preferred embodiment of the invention, the high-efficiency hair loss prevention and hair growth promotion composition is applied to cosmetics, skin care and personal care products.
The invention has the beneficial effects that: the efficient hair loss prevention and hair growth promoting composition achieves the purposes of promoting the growth of capillary vessels, activating hair follicles and continuously and healthily growing hair by inhibiting the generation of collagen around the hair follicles, avoiding fibrosis, expanding peripheral capillary vessels and inhibiting sebum secretion.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The first embodiment is as follows:
a composition with high efficiency for preventing hair loss and promoting hair growth is provided, which comprises water, diaminopyrimidine oxide, adenosine, caffeine, nicotinamide, vitamin E, resveratrol, herba Centellae extract, alcohol, Mentholum, and Borneolum Syntheticum. The high-efficiency hair loss prevention and hair growth promoting composition comprises the following components in parts by weight: the composition comprises, by mass, the balance of water, 1.5% of diaminopyrimidine oxide, 0.5% of adenosine, 0.2% of caffeine, 4% of nicotinamide, 0.2% of vitamin E, 0.5% of resveratrol, 0.4% of centella asiatica extract, 15% of alcohol, 0.1% of menthol and 0.2% of borneol.
The production process of the high-efficiency hair loss prevention and hair growth promoting composition comprises the following steps:
(1) mixing and dissolving alcohol, vitamin E, resveratrol, menthol and borneol uniformly at normal temperature and normal pressure for later use;
(2) sequentially adding diaminopyrimidine oxide, adenosine, caffeine, nicotinamide and herba Centellae extract into water at normal temperature and pressure, stirring to dissolve completely, adding a mixture of pre-dissolved ethanol, vitamin E, resveratrol, menthol and borneol, and stirring uniformly;
(3) and (4) filling and packaging, wherein the finished product can be put in a warehouse after being detected to be qualified, and can also be directly used for subsequent experiments.
Effect experiment: in the double-blind clinical trial and placebo contrast test experiment, 35 severe alopecia subjects were aged 20-40 years. The same packaged high-efficiency hair loss prevention and hair growth promoting composition or placebo is used twice a day for 6 months. The total number of hairs in a specific area was visually counted using a magnifying glass, and the number of people who reduced the hair loss and the number of people who promoted new hairs were counted, respectively, and the results are shown in the following table.
Clinical trials using example one showed that the example one formulation exhibited its anti-hair loss properties and by measuring hair volume, it significantly increased hair growth.
Example two:
a composition with high efficiency for preventing hair loss and promoting hair growth is provided, which comprises water, diaminopyrimidine oxide, adenosine, caffeine, nicotinamide, vitamin E, resveratrol, alcohol, menthol and borneol. The high-efficiency hair loss prevention and hair growth promoting composition comprises the following components in parts by weight: the composition comprises, by mass, the balance of water, 1% of diaminopyrimidine oxide, 0.3% of adenosine, 0.2% of caffeine, 3% of nicotinamide, 0.2% of vitamin E, 0.4% of resveratrol, 20% of alcohol, 0.08% of menthol and 0.1% of borneol. The production process is the same as the first embodiment.
Example three:
a composition with high efficiency for preventing hair loss and promoting hair growth is provided, which comprises water, diaminopyrimidine oxide, adenosine, caffeine, nicotinamide, resveratrol, herba Centellae extract, alcohol, and Mentholum. The high-efficiency hair loss prevention and hair growth promoting composition comprises the following components in parts by weight: the composition comprises, by mass, the balance of water, 0.8% of diaminopyrimidine oxide, 0.6% of adenosine, 0.5% of caffeine, 6% of nicotinamide, 0.5% of resveratrol, 0.8% of centella asiatica extract, 25% of alcohol and 0.04% of menthol. The production process is the same as the first embodiment.
Example four:
a composition with high efficiency for preventing hair loss and promoting hair growth is provided, which comprises water, diaminopyrimidine oxide, adenosine, caffeine, nicotinamide, vitamin E, resveratrol, herba Centellae extract, alcohol, and Borneolum Syntheticum. The high-efficiency hair loss prevention and hair growth promoting composition comprises the following components in parts by weight: the composition comprises, by mass, the balance of water, 0.2% of diaminopyrimidine oxide, 1% of adenosine, 0.5% of caffeine, 6% of nicotinamide, 0.3% of vitamin E, 1% of resveratrol, 1% of centella asiatica extract, 35% of alcohol and 0.2% of borneol. The production process is the same as the first embodiment.
The efficient hair loss preventing and growing composition disclosed by the invention can prevent and improve the condition of hair loss by acting on a deep structure of a root in a growing period, keeps a cortex sanitary, breathable and non-greasy, enables the head to be more comfortable and healthy, converges excessively hypertrophic sebaceous glands, has the effects of reducing sebum secretion and promoting blood circulation, has the effects of cleaning hair follicles of fallen hair, stimulating the hair follicles, activating and promoting hair regrowth. Can be further used as a composition in cosmetic, skin care, and personal care formulations. In the formula of the hair loss preventing and hair growing composition, a plurality of active components are mutually compatible and synergically synergistic, so that the hair loss preventing and hair growing composition has a good hair loss preventing and hair growing effect and has a good effect on hair care and scalp nutrition. The invention has strong stability, small side effect, no irritation and wide application.
The above description is only an embodiment of the present invention, and not intended to limit the scope of the present invention, and all modifications of equivalent structures and equivalent processes, which are made by the present specification, or directly or indirectly applied to other related technical fields, are included in the scope of the present invention.
Claims (10)
1. The efficient hair loss prevention and hair growth promoting composition is characterized by comprising water, high hair loss prevention and hair growth activity factors, antioxidant anti-inflammatory activity factors and a freshener, wherein the content of each component of the efficient hair loss prevention and hair growth promoting composition is as follows: the balance of water, 0.1 to 10 percent of high active factor for preventing hair loss and growing hair, 0.1 to 5 percent of antioxidant and anti-inflammatory active factor and 0.01 to 40 percent of freshener.
2. The high-efficiency hair loss prevention and growth promotion composition according to claim 1, which consists of water, hair loss prevention and growth promotion active factors, antioxidant and anti-inflammatory active factors and a cooling agent, wherein the contents of the components of the high-efficiency hair loss prevention and growth promotion composition are as follows: the balance of water, 0.1 to 10 percent of high active factor for preventing hair loss and growing hair, 0.1 to 5 percent of antioxidant and anti-inflammatory active factor and 0.01 to 40 percent of freshener.
3. The composition for promoting hair loss and growth according to claim 1 or 2, wherein the factor with high activity for promoting hair loss and growth is one or more of diaminopyrimidine oxide, adenosine, caffeine, and nicotinamide.
4. The composition for preventing hair loss and promoting hair growth according to claim 3, wherein the source of diaminopyrimidine oxide is synthetically derived; the caffeine is obtained from plants; the source of nicotinamide is synthetically derived.
5. The composition for preventing alopecia and promoting hair growth as claimed in claim 1 or 2, wherein the antioxidant anti-inflammatory active factor is one or more of vitamin E, resveratrol, and centella asiatica extract.
6. The composition for preventing alopecia and promoting hair growth as claimed in claim 5, wherein the source of vitamin E is obtained by synthesis; the source of the resveratrol is obtained by biological fermentation; the centella asiatica extract is obtained by biological extraction.
7. The composition for preventing alopecia and promoting hair growth as claimed in claim 1 or 2, wherein the cooling agent is one or more of alcohol, menthol and borneol.
8. The composition for preventing alopecia and promoting hair growth as claimed in claim 7, wherein the source of alcohol is obtained by fermenting plants; the source of the menthol is obtained by plant extraction; the source of the borneol is obtained by extracting plants.
9. The efficient hair loss preventing and growing composition according to claim 1, wherein the efficient hair loss preventing and growing composition comprises water, diaminopyrimidine oxide, adenosine, caffeine, nicotinamide, vitamin E, resveratrol, centella asiatica extract, alcohol, menthol and borneol, and the content of each component of the efficient hair loss preventing and growing composition is as follows: the composition comprises, by mass, the balance of water, 0.2-1.5% of diaminopyrimidine oxide, 0.3-1% of adenosine, 0.2-0.5% of caffeine, 3-6% of nicotinamide, 0.2-0.5% of vitamin E, 0.4-1% of resveratrol, 0.4-1% of centella asiatica extract, 15-35% of alcohol, 0.04-0.1% of menthol and 0.1-0.2% of borneol.
10. The high-efficiency hair loss prevention and hair growth promoting composition according to claim 1, wherein the high-efficiency hair loss prevention and hair growth promoting composition is applied to cosmetics, skin care products and personal care products.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010045232.4A CN111228172A (en) | 2020-01-16 | 2020-01-16 | High-efficiency hair loss prevention and hair growth composition |
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| CN202010045232.4A CN111228172A (en) | 2020-01-16 | 2020-01-16 | High-efficiency hair loss prevention and hair growth composition |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113398019A (en) * | 2021-05-24 | 2021-09-17 | 上海曜爱生物科技有限公司 | Nano microemulsion system composition with anti-hair loss and hair growth functions, preparation method and application |
| CN113750023A (en) * | 2021-09-23 | 2021-12-07 | 广州市番禺成业化妆品厂 | Scalp nutritional composition for promoting hair growth |
| CN114903924A (en) * | 2021-02-10 | 2022-08-16 | 伽蓝（集团）股份有限公司 | Composition containing myrobalan fruit extract, preparation method, application and hair care product |
| CN115245570A (en) * | 2022-06-16 | 2022-10-28 | 上海松皓生物科技有限公司 | Anti-hair loss and hair-nourishing composition and application thereof |
| CN116421491A (en) * | 2023-05-30 | 2023-07-14 | 广州市名嫡化妆品有限公司 | Adenosine aqueous composition, adenosine solution, and preparation method and application thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114903924A (en) * | 2021-02-10 | 2022-08-16 | 伽蓝（集团）股份有限公司 | Composition containing myrobalan fruit extract, preparation method, application and hair care product |
| CN113398019A (en) * | 2021-05-24 | 2021-09-17 | 上海曜爱生物科技有限公司 | Nano microemulsion system composition with anti-hair loss and hair growth functions, preparation method and application |
| CN113750023A (en) * | 2021-09-23 | 2021-12-07 | 广州市番禺成业化妆品厂 | Scalp nutritional composition for promoting hair growth |
| CN115245570A (en) * | 2022-06-16 | 2022-10-28 | 上海松皓生物科技有限公司 | Anti-hair loss and hair-nourishing composition and application thereof |
| CN116421491A (en) * | 2023-05-30 | 2023-07-14 | 广州市名嫡化妆品有限公司 | Adenosine aqueous composition, adenosine solution, and preparation method and application thereof |
| CN116421491B (en) * | 2023-05-30 | 2023-11-10 | 广州市名嫡化妆品有限公司 | Adenosine aqueous composition, adenosine solution, and preparation method and application thereof |
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Application publication date: 20200605 |