CN111225564A - Antibacterial composition - Google Patents
Antibacterial composition Download PDFInfo
- Publication number
- CN111225564A CN111225564A CN201880067226.XA CN201880067226A CN111225564A CN 111225564 A CN111225564 A CN 111225564A CN 201880067226 A CN201880067226 A CN 201880067226A CN 111225564 A CN111225564 A CN 111225564A
- Authority
- CN
- China
- Prior art keywords
- acid
- metal salt
- alkaline earth
- metal salts
- alkali metal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/02—Saturated carboxylic acids or thio analogues thereof; Derivatives thereof
- A01N37/04—Saturated carboxylic acids or thio analogues thereof; Derivatives thereof polybasic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
- A01N59/06—Aluminium; Calcium; Magnesium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/3463—Organic compounds; Microorganisms; Enzymes
- A23L3/3481—Organic compounds containing oxygen
- A23L3/3508—Organic compounds containing oxygen containing carboxyl groups
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/3463—Organic compounds; Microorganisms; Enzymes
- A23L3/3526—Organic compounds containing nitrogen
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/358—Inorganic compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/90—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in food processing or handling, e.g. food conservation
Abstract
The invention provides an antibacterial composition which can be easily dissolved in water to produce a chemical liquid without generating any precipitate. The antibacterial composition of the present invention comprises calcined calcium, and a metal salt of at least one organic acid selected from the group consisting of: alkali metal salts of citric acid, alkaline earth metal salts of citric acid, alkali metal salts of gluconic acid, alkaline earth metal salts of gluconic acid, alkali metal salts of ascorbic acid, alkaline earth metal salts of ascorbic acid, alkali metal salts of malic acid, alkaline earth metal salts of malic acid, alkali metal salts of succinic acid, alkaline earth metal salts of succinic acid, alkali metal salts of aspartic acid, alkaline earth metal salts of aspartic acid, alkali metal salts of acetic acid, alkaline earth metal salts of acetic acid, alkali metal salts of ethylenediaminetetraacetic acid, and alkaline earth metal salts of ethylenediaminetetraacetic acid.
Description
Technical Field
The present invention relates to an antibacterial composition.
Background
In recent years, due to the increased awareness of the sanitary environment, wet tissues or towels are used for dining indoors and outdoors. In addition, after using the toilet, a toilet cleaning sheet is used in order to easily remove the dirty part.
Patent document 1 discloses a water-disintegrable sheet obtained by impregnating a base paper sheet added with a water-soluble binder with a chemical solution, wherein the base paper sheet is obtained by processing a plurality of base paper sheets in a sheet-like manner, and has a basis weight of 30 to 150gsm, a blending ratio of softwood pulp to hardwood pulp is set to be less than 1/1, a content of the water-soluble binder is increased from the inner side in the thickness direction of the base paper sheet toward the front and back surfaces, and the chemical solution contains a crosslinking agent that undergoes a crosslinking reaction with the water-soluble binder and a degerming agent, and the chemical solution is impregnated in an amount of 150 to 300 wt% with respect to the weight of the base paper sheet.
Patent document 2 discloses an antibacterial composition containing the following (a), (B), (C), (D) and (E).
(A) Chitosan and/or salt thereof
(B)0.001 to 0.10 mass% of quaternary ammonium salt
(C) Alcohols
(D) 0.01-1% by mass of betaine amphoteric surfactant
(E) Water (W)
Documents of the prior art
Patent document
Patent document 1: japanese patent laid-open publication No. 2016-
Patent document 2: japanese patent laid-open publication No. 2016-94410
Disclosure of Invention
Problems to be solved by the invention
The water-disintegratable sheet of patent document 1 is produced by impregnating a base paper sheet with a chemical solution. Therefore, as in the antibacterial composition of patent document 2, a chemical liquid is generally prepared by dissolving benzalkonium chloride (quaternary ammonium salt) in water.
However, in order to dissolve benzalkonium chloride in water and prepare an aqueous solution of a predetermined concentration without causing precipitation, it is necessary to control the production conditions, and therefore, benzalkonium chloride is usually dissolved in water to prepare an aqueous solution and then supplied.
Therefore, when benzalkonium chloride is transported, there is a problem that the volume and weight of the benzalkonium chloride aqueous solution increase and the transportation cost and storage cost increase, although the content of benzalkonium chloride itself contained in the aqueous solution is small.
The invention provides an antibacterial composition which can be easily dissolved in water to produce chemical liquid medicine under the condition of basically not generating precipitate, and can inhibit transportation cost and storage cost.
Means for solving the problems
The antibacterial composition of the present invention comprises 100 parts by mass of calcined calcium, and
100-600 parts by mass of at least one organic acid metal salt selected from the following:
alkali metal salts of citric acid, alkaline earth metal salts of citric acid, alkali metal salts of gluconic acid, alkaline earth metal salts of gluconic acid, alkali metal salts of ascorbic acid, alkaline earth metal salts of ascorbic acid, alkali metal salts of malic acid, alkaline earth metal salts of malic acid, alkali metal salts of succinic acid, alkaline earth metal salts of succinic acid, alkali metal salts of aspartic acid, alkaline earth metal salts of aspartic acid, alkali metal salts of acetic acid, alkaline earth metal salts of acetic acid, alkali metal salts of ethylenediaminetetraacetic acid, and alkaline earth metal salts of ethylenediaminetetraacetic acid.
ADVANTAGEOUS EFFECTS OF INVENTION
The antibacterial composition of the present invention can be easily dissolved in water without substantially controlling the conditions for dissolution in water, and can produce a chemical liquid medicine substantially free from precipitation. The obtained chemical liquid has excellent antibacterial property.
Detailed Description
The antibacterial composition of the present invention comprises calcined calcium and a metal salt of an organic acid.
(calcined calcium)
The antibacterial composition contains calcined calcium. As the calcined calcium, scallop shell calcined calcium is preferable.
The calcined calcium is obtained by calcining or heating a calcium raw material of animal origin, such as oyster shell, scallop shell, arctium shell, eggshell, coral shell, etc., whose main component is calcium carbonate before calcination, at a temperature of 600 ℃ or higher, preferably 900 to 1200 ℃ for about 15 to 60 minutes, and the main component is calcium oxide.
(Metal salt of organic acid)
The antibacterial composition contains a metal salt of an organic acid.
As the metal salt of an organic acid, at least one metal salt of an organic acid selected from the group consisting of: alkali metal salts of citric acid, alkaline earth metal salts of citric acid, alkali metal salts of gluconic acid, alkaline earth metal salts of gluconic acid, alkali metal salts of ascorbic acid, alkaline earth metal salts of ascorbic acid, alkali metal salts of malic acid, alkaline earth metal salts of malic acid, alkali metal salts of succinic acid, alkaline earth metal salts of succinic acid, alkali metal salts of aspartic acid, alkaline earth metal salts of aspartic acid, alkali metal salts of acetic acid, alkaline earth metal salts of acetic acid, alkali metal salts of ethylenediaminetetraacetic acid, and alkaline earth metal salts of ethylenediaminetetraacetic acid. The metal salts of organic acids may be used alone or in combination of two or more.
The alkali metal salt of citric acid is not particularly limited, but sodium citrate and potassium citrate are preferable, and potassium citrate is more preferable.
The alkaline earth metal salt of citric acid is not particularly limited, and examples thereof include: magnesium citrate, calcium citrate, barium citrate, etc., preferably magnesium citrate and calcium citrate.
The alkali metal salt of gluconic acid is not particularly limited, but sodium gluconate and potassium gluconate are preferred, and sodium gluconate is more preferred.
The alkaline earth metal salt of gluconic acid is not particularly limited, and examples thereof include: magnesium gluconate, calcium gluconate, barium gluconate, and the like, and preferably magnesium gluconate and calcium gluconate.
The alkali metal salt of ascorbic acid is not particularly limited, but sodium ascorbate and potassium ascorbate are preferable, and sodium ascorbate is more preferable.
The alkaline earth metal salt of ascorbic acid is not particularly limited, and examples thereof include: magnesium ascorbate, calcium ascorbate, barium ascorbate, etc., preferably magnesium ascorbate and calcium ascorbate.
The alkali metal salt of malic acid is not particularly limited, but sodium malate and potassium malate are preferred, and sodium malate is more preferred.
The alkaline earth metal salt of malic acid is not particularly limited, and examples thereof include: magnesium malate, calcium malate, barium malate, etc., preferably magnesium malate and calcium malate.
The alkali metal salt of succinic acid is not particularly limited, but sodium succinate and potassium succinate are preferable, and sodium succinate is more preferable.
The alkaline earth metal salt of succinic acid is not particularly limited, and examples thereof include: magnesium succinate, calcium succinate, barium succinate, etc., preferably magnesium succinate and calcium succinate.
The alkali metal salt of aspartic acid is not particularly limited, but sodium aspartate and potassium aspartate are preferable, and sodium aspartate is more preferable.
The alkaline earth metal salt of aspartic acid is not particularly limited, and examples thereof include: magnesium aspartate, calcium aspartate, barium aspartate, etc., and preferably magnesium aspartate and calcium aspartate.
The alkali metal salt of acetic acid is not particularly limited, but sodium acetate and potassium acetate are preferable, and sodium acetate is more preferable.
The alkaline earth metal salt of acetic acid is not particularly limited, and examples thereof include: magnesium acetate, calcium acetate, barium acetate, etc., preferably magnesium acetate and calcium acetate.
The alkali metal salt of ethylenediaminetetraacetic acid is not particularly limited, but sodium ethylenediaminetetraacetate and potassium ethylenediaminetetraacetate are preferable, sodium ethylenediaminetetraacetate is more preferable, and disodium ethylenediaminetetraacetate is particularly preferable.
The alkaline earth metal salt of ethylenediaminetetraacetic acid is not particularly limited, and examples thereof include: magnesium ethylenediaminetetraacetate, calcium ethylenediaminetetraacetate, barium ethylenediaminetetraacetate, etc., preferably magnesium ethylenediaminetetraacetate and calcium ethylenediaminetetraacetate.
The metal salt of an organic acid is preferably an alkali metal salt of citric acid, an alkaline earth metal salt of citric acid, an alkali metal salt of gluconic acid, an alkaline earth metal salt of gluconic acid, an alkali metal salt of malic acid, an alkali metal salt of ethylenediaminetetraacetic acid, and an alkaline earth metal salt of ethylenediaminetetraacetic acid, and more preferably an alkali metal salt of citric acid, an alkali metal salt of gluconic acid, an alkaline earth metal salt of gluconic acid, an alkali metal salt of malic acid, an alkaline earth metal salt of malic acid, an alkali metal salt of ethylenediaminetetraacetic acid, and an alkaline earth metal salt of ethylenediaminetetraacetic acid, particularly preferred are alkali metal salts of malic acid, alkaline earth metal salts of malic acid, alkali metal salts of ethylenediaminetetraacetic acid, and alkaline earth metal salts of ethylenediaminetetraacetic acid, and most preferred are alkali metal salts of ethylenediaminetetraacetic acid and alkaline earth metal salts of ethylenediaminetetraacetic acid.
The metal salt of an organic acid preferably contains: at least one metal salt of gluconic acid selected from the group consisting of alkali metal salts of gluconic acid and alkaline earth metal salts of gluconic acid, and
at least one organic acid metal salt selected from the group consisting of an alkali metal salt of succinic acid, an alkaline earth metal salt of succinic acid, an alkali metal salt of malic acid, an alkaline earth metal salt of malic acid, an alkali metal salt of citric acid and an alkaline earth metal salt of citric acid.
The metal salt of an organic acid more preferably contains: alkali metal salt of gluconic acid, and
an alkali metal salt of at least one organic acid selected from the group consisting of an alkali metal salt of succinic acid, an alkali metal salt of malic acid and an alkali metal salt of citric acid.
The metal salt of an organic acid particularly preferably contains: sodium salt of gluconic acid, and
at least one sodium salt of an organic acid selected from the group consisting of a sodium salt of succinic acid, a sodium salt of malic acid and a sodium salt of citric acid.
The metal salt of an organic acid preferably contains: at least one metal salt of gluconic acid selected from the group consisting of alkali metal salts of gluconic acid and alkaline earth metal salts of gluconic acid, and
at least one organic acid metal salt selected from the group consisting of an alkali metal salt of succinic acid, an alkaline earth metal salt of succinic acid, an alkali metal salt of malic acid and an alkaline earth metal salt of malic acid.
The metal salt of an organic acid more preferably contains: alkali metal salt of gluconic acid, and
at least one organic acid alkali metal salt selected from the group consisting of succinic acid alkali metal salts and malic acid alkali metal salts.
The metal salt of an organic acid particularly preferably contains: sodium salt of gluconic acid, and
at least one sodium salt of an organic acid selected from the group consisting of a sodium salt of succinic acid and a sodium salt of malic acid.
The metal salt of an organic acid preferably contains: at least one metal salt of gluconic acid selected from the group consisting of alkali metal salts of gluconic acid and alkaline earth metal salts of gluconic acid, and
a metal salt of at least one organic acid selected from the group consisting of an alkali metal salt of succinic acid and an alkaline earth metal salt of succinic acid.
The metal salt of an organic acid more preferably contains an alkali metal salt of gluconic acid and an alkali metal salt of succinic acid.
The metal salt of an organic acid particularly preferably contains a sodium salt of gluconic acid and a sodium salt of succinic acid.
When the metal salt of an organic acid contains a metal salt of gluconic acid, the content of the metal salt of gluconic acid in the metal salt of an organic acid is preferably 30 to 70 mass%, more preferably 35 to 65 mass%, and particularly preferably 40 to 60 mass%.
The metal salt of an organic acid preferably contains: at least one metal salt of citric acid selected from alkali metal salts of citric acid and alkaline earth metal salts of citric acid, and
at least one organic acid metal salt selected from the group consisting of an alkali metal salt of succinic acid, an alkaline earth metal salt of succinic acid, an alkali metal salt of malic acid, an alkaline earth metal salt of malic acid, an alkali metal salt of aspartic acid, an alkaline earth metal salt of aspartic acid, an alkali metal salt of ethylenediaminetetraacetic acid, and an alkaline earth metal salt of ethylenediaminetetraacetic acid.
The metal salt of an organic acid more preferably contains: alkali metal salts of citric acid, and
at least one organic acid alkali metal salt selected from the group consisting of an alkali metal salt of succinic acid, an alkali metal salt of malic acid, an alkali metal salt of aspartic acid and an alkali metal salt of ethylenediaminetetraacetic acid.
The metal salt of an organic acid particularly preferably contains: sodium salt of citric acid, and
at least one organic acid sodium salt selected from the group consisting of a succinic acid sodium salt, a malic acid sodium salt, an aspartic acid sodium salt and an ethylenediaminetetraacetic acid sodium salt.
The metal salt of an organic acid preferably contains: at least one metal salt of citric acid selected from alkali metal salts of citric acid and alkaline earth metal salts of citric acid, and
at least one organic acid metal salt selected from the group consisting of an alkali metal salt of succinic acid, an alkaline earth metal salt of succinic acid, an alkali metal salt of malic acid and an alkaline earth metal salt of malic acid.
The metal salt of an organic acid more preferably contains: alkali metal salts of citric acid, and
at least one organic acid alkali metal salt selected from the group consisting of succinic acid alkali metal salts and malic acid alkali metal salts.
The metal salt of an organic acid particularly preferably contains: sodium salt of citric acid, and
at least one sodium salt of an organic acid selected from the group consisting of a sodium salt of succinic acid and a sodium salt of malic acid.
The metal salt of an organic acid preferably contains: at least one metal salt of citric acid selected from alkali metal salts of citric acid and alkaline earth metal salts of citric acid, and
at least one metal salt of succinic acid selected from the group consisting of alkali metal salts of succinic acid and alkaline earth metal salts of succinic acid.
More preferably, the metal salt of an organic acid contains an alkali metal salt of citric acid and an alkali metal salt of succinic acid.
The metal salt of an organic acid particularly preferably contains a sodium salt of citric acid and a sodium salt of succinic acid.
When the metal salt of an organic acid contains a metal salt of citric acid, the content of the metal salt of citric acid in the metal salt of an organic acid is preferably 30 to 70% by mass, more preferably 35 to 65% by mass, and particularly preferably 40 to 60% by mass.
The content of the metal salt of an organic acid in the antibacterial composition is 100 parts by mass or more, preferably 150 parts by mass or more, more preferably 200 parts by mass or more, more preferably 220 parts by mass or more, and particularly preferably 250 parts by mass or more, relative to 100 parts by mass of the calcined calcium. When the content of the metal salt of the organic acid is 100 parts by mass or more, the antibacterial composition has excellent antibacterial properties.
The content of the metal salt of an organic acid in the antibacterial composition is 600 parts by mass or less, preferably 500 parts by mass or less, more preferably 450 parts by mass or less, and particularly preferably 350 parts by mass or less, per 100 parts by mass of the calcined calcium. When the content of the metal salt of the organic acid is 600 parts by mass or less, the metal salt of the organic acid can be dissolved in the antibacterial composition without precipitation.
In the case where the organic acid metal salt contains a plurality of kinds, "the content of the organic acid metal salt" means the total content of the organic acid metal salts.
Since the antibacterial composition contains calcined calcium and a metal salt of an organic acid, the antibacterial composition can be easily dissolved in water without precipitation while maintaining the antibacterial properties of the calcined calcium. In this case, the chemical liquid having antibacterial properties can be prepared simply by adding the antibacterial composition to water and dissolving the composition without precisely controlling the dissolution conditions. The obtained chemical liquid hardly causes precipitation of the antibacterial composition, particularly calcined calcium, even if the temperature changes.
(carbonates, bicarbonates, and silicates)
The antimicrobial composition preferably contains a carbonate, bicarbonate or silicate. The antibacterial property of the antibacterial composition can be further improved, and excellent cleaning property can be imparted to the antibacterial composition.
Examples of the carbonate include: sodium carbonate, potassium carbonate, etc., and sodium carbonate is preferred.
Examples of the bicarbonate include: sodium hydrogen carbonate, potassium hydrogen carbonate and the like, and sodium hydrogen carbonate is preferable.
As silicates, for example, with M2O/nSiO2(wherein M is sodium or potassium, and n is SiO2The number of moles of) is described, and specific examples thereof include: sodium orthosilicate, potassium orthosilicate, sodium sesquisilicate, potassium sesquisilicate, sodium metasilicate, potassium metasilicate, sodium silicate No. 1, potassium silicate No. 1, sodium silicate No. 2, potassium silicate No. 2, sodium silicate No. 3, potassium silicate No. 3, etc. prescribed in JIS K1408, with sodium silicate being preferred.
The ratio of the mass of the metal salt of an organic acid to the mass of the carbonate (mass of the metal salt of an organic acid/mass of the carbonate) in the antibacterial composition is preferably 1 to 50, more preferably 2 to 30, more preferably 3 to 20, and particularly preferably 3.5 to 10. When the ratio of the mass of the metal salt of an organic acid to the mass of the carbonate (mass of the metal salt of an organic acid/mass of the carbonate) is within the above range, the antibacterial property of the antibacterial composition can be improved, and the antibacterial composition can be provided with a cleaning property.
The ratio of the mass of the metal salt of an organic acid to the mass of the bicarbonate (mass of the metal salt of an organic acid/mass of the bicarbonate) in the antibacterial composition is preferably 1 to 50, more preferably 2 to 30, more preferably 3 to 20, and particularly preferably 3.5 to 10. When the ratio of the mass of the metal salt of an organic acid to the mass of the bicarbonate salt (mass of the metal salt of an organic acid/mass of the bicarbonate salt) is within the above range, the antibacterial property of the antibacterial composition can be improved, and the antibacterial composition can be provided with a cleaning property.
The ratio of the mass of the metal salt of an organic acid to the mass of the silicate in the antibacterial composition (mass of the metal salt of an organic acid/mass of the silicate) is preferably 1 to 50, more preferably 2 to 30, particularly preferably 3 to 20, and most preferably 3.5 to 10. When the ratio of the mass of the metal salt of an organic acid to the mass of the silicate (mass of the metal salt of an organic acid/mass of the silicate) is within the above range, the antibacterial property of the antibacterial composition can be improved, and the antibacterial composition can be provided with cleaning property.
(antibacterial composition)
The antibacterial composition can be produced by mixing calcined calcium with a metal salt of an organic acid using a general mixing method.
Points of use of the antibacterial composition will be described. The antibacterial composition can be dissolved in water to produce an antibacterial chemical solution. When the antibacterial composition is dissolved in water, there is no need to specifically control the dissolution conditions, and the antibacterial composition can be easily dissolved in water simply by adding the antibacterial composition to water.
The content of the antibacterial composition in the chemical liquid is preferably 0.01 to 10 parts by mass, more preferably 0.05 to 5 parts by mass, even more preferably 0.07 to 3 parts by mass, and particularly preferably 0.08 to 2 parts by mass, based on 100 parts by mass of water.
The obtained chemical liquid does not substantially cause precipitation of the antibacterial composition, particularly precipitation of calcined calcium. Therefore, when the chemical liquid is used, the precipitate does not need to be filtered, and the facility and the manufacturing process can be simplified.
The obtained chemical liquid does not require addition of a preservative, does not deteriorate, can maintain excellent antibacterial properties for a long period of time, and can be stably stored. The preservative includes those commonly used, and examples thereof include: parabens or salts thereof (parabens), phenoxyethanol, benzoic acid or salts thereof, sorbic acid or salts thereof, chlorhexidine gluconate, and the like.
The antimicrobial sheet can be produced by impregnating a cloth (nonwoven fabric, woven fabric, etc.) with a chemical solution. The antibacterial sheet can be used as, for example, a towel, a wiping sheet, a toilet cleaning sheet, and the like.
Since the antibacterial composition does not contain a compound harmful to the human body, foods such as vegetables and fruits can be immersed in a chemical solution to impart antibacterial properties to the foods and improve the storage stability.
Further, the chemical liquid may be used as a cleaning agent to clean the body by wiping the body such as hands and feet with the chemical liquid.
In addition, since water is contained in the shampoo (shampoo), the conditioner, and the cleansing agent for cleansing the body, the antibacterial composition can be dissolved in water to impart antibacterial properties to the shampoo, the conditioner, and the cleansing agent, and thus the shampoo, the conditioner, and the cleansing agent can be stably stored for a long period of time.
By adding the antibacterial composition to the aqueous coating material, antibacterial properties can be imparted to the aqueous coating material. The aqueous coating material contains water and a binder component dispersed in the water. Since the antibacterial composition can be dissolved in water without causing any substantial precipitation, the antibacterial composition can be uniformly contained in the aqueous coating material, and the resulting coating film can be uniformly contained to form a coating film having antibacterial properties.
The cosmetic may contain an antibacterial composition to impart antibacterial properties to the cosmetic. The cosmetic may contain water, and examples thereof include a cosmetic water.
The antibacterial composition may be mixed with a synthetic resin and used. The antibacterial composition and the synthetic resin are supplied to an extruder, melt-kneaded, and extruded from the extruder to be molded into a molded article (for example, a sheet, a food storage bag, a daily necessity, a vehicle interior material, and a building interior material) having a desired shape, whereby a molded article having antibacterial properties can be obtained.
Examples
The present invention will be described more specifically with reference to the following examples, but the present invention is not limited to these examples.
Examples 1 to 36 and comparative examples 1 to 4
Calcined scallop shell calcium, sodium citrate, potassium citrate, sodium gluconate, potassium gluconate, sodium malate, sodium succinate, sodium aspartate, disodium ethylenediaminetetraacetate, sodium carbonate, potassium carbonate, sodium bicarbonate, and sodium silicate were mixed in given amounts shown in tables 1 to 4, respectively, to prepare an antibacterial composition.
The antibacterial properties and solubility of the obtained antibacterial compositions were measured as follows, and the results are shown in tables 1 to 4.
(antibacterial property)
Test samples were prepared by adding and dissolving 1 part by mass of the antibacterial composition in 1000 parts by mass of water. Escherichia coli (Escherichia coli) was inoculated into a common agar medium and cultured at 35 ℃ for 24 hours. After the culture, the amount of the culture medium was adjusted to 10 using sterile physiological saline7The test bacterial suspension was designated as the/mL bacterial suspension.
The test bacterial suspension (100. mu.L) was inoculated into 200mL of the test sample and cultured at 25 ℃. After 5 minutes and 30 minutes of inoculation, a 10-fold dilution series of the prepared test sample was diluted with a sterile physiological saline solution to prepare a test solution, which was inoculated into an SCDLP agar medium and cultured at 35 ℃ for 48 hours. After the culture, the number of formed colonies was counted and converted into viable cell count (cfu/mL).
In addition, the test was carried out in the same manner as described above using sterile phosphate-buffered physiological saline as a control, and the number of viable bacteria was converted to the initial number of bacteria (cfu/mL).
Antibacterial property (%) ═ 100 × (initial number of viable bacteria-number of viable bacteria)/(initial number of bacteria)
(solubility)
0.4 part by mass of the antibacterial composition was added to 100 parts by mass of water and dissolved to prepare a chemical solution. The obtained chemical solution WAs left to stand for 24 hours, and then the Turbidity (TUR) of the chemical solution WAs measured using a measuring instrument (product name "WA-PT-4 DG" manufactured by Co., Ltd.). The turbidity of the chemical solution was measured using a formalin solution as a standard solution. The turbidity of 20 degrees formalin or higher cases were described as "OVER".
(related application)
This application is based on the priority claim of japanese patent application No. 2017-200181 filed on 2017, 10, 16, which is incorporated by reference in its entirety into this specification.
Industrial applicability
The antibacterial composition of the present invention can be easily dissolved in water to produce a chemical liquid. The antibacterial sheet can be produced by using a chemical liquid, or the antibacterial property can be imparted to food. Chemical solutions may also be used as cleaning agents. By adding an antibacterial composition to an object such as a detergent, a water-based paint, a cosmetic, or a synthetic resin, antibacterial properties can be imparted to the object.
Claims (10)
1. An antimicrobial composition comprising:
calcined calcium of 100 parts by mass, and
100-600 parts by mass of a metal salt of at least one organic acid selected from the following:
alkali metal salts of citric acid, alkaline earth metal salts of citric acid, alkali metal salts of gluconic acid, alkaline earth metal salts of gluconic acid, alkali metal salts of ascorbic acid, alkaline earth metal salts of ascorbic acid, alkali metal salts of malic acid, alkaline earth metal salts of malic acid, alkali metal salts of succinic acid, alkaline earth metal salts of succinic acid, alkali metal salts of aspartic acid, alkaline earth metal salts of aspartic acid, alkali metal salts of acetic acid, alkaline earth metal salts of acetic acid, alkali metal salts of ethylenediaminetetraacetic acid, and alkaline earth metal salts of ethylenediaminetetraacetic acid.
2. The antimicrobial composition according to claim 1,
the metal salt of an organic acid is at least one metal salt of an organic acid selected from the group consisting of an alkali metal salt of citric acid, an alkaline earth metal salt of citric acid, an alkali metal salt of gluconic acid, an alkaline earth metal salt of gluconic acid, an alkali metal salt of malic acid, an alkaline earth metal salt of malic acid, an alkali metal salt of ethylenediaminetetraacetic acid, and an alkaline earth metal salt of ethylenediaminetetraacetic acid.
3. The antimicrobial composition according to claim 1,
the metal salt of an organic acid contains: at least one metal salt of gluconic acid selected from the group consisting of alkali metal salts of gluconic acid and alkaline earth metal salts of gluconic acid, and
at least one organic acid metal salt selected from the group consisting of an alkali metal salt of succinic acid, an alkaline earth metal salt of succinic acid, an alkali metal salt of malic acid, an alkaline earth metal salt of malic acid, an alkali metal salt of citric acid, and an alkaline earth metal salt of citric acid.
4. The antimicrobial composition according to claim 3,
the metal salt of an organic acid contains 30 to 70 mass% of a metal salt of gluconic acid.
5. The antimicrobial composition according to claim 1,
the metal salt of an organic acid contains:
at least one metal salt of citric acid selected from alkali metal salts of citric acid and alkaline earth metal salts of citric acid, and
at least one organic acid metal salt selected from the group consisting of an alkali metal salt of succinic acid, an alkaline earth metal salt of succinic acid, an alkali metal salt of malic acid, an alkaline earth metal salt of malic acid, an alkali metal salt of aspartic acid, an alkaline earth metal salt of aspartic acid, an alkali metal salt of ethylenediaminetetraacetic acid, and an alkaline earth metal salt of ethylenediaminetetraacetic acid.
6. The antimicrobial composition according to claim 5,
the metal salt of an organic acid contains 30 to 70 mass% of a metal salt of citric acid.
7. The antibacterial composition according to claim 1 or 2,
the metal salt of the organic acid is a sodium salt of the organic acid or a potassium salt of the organic acid.
8. The antimicrobial composition of claim 1, further comprising a carbonate or bicarbonate salt.
9. The antimicrobial composition according to claim 8,
the carbonate is sodium carbonate or potassium carbonate.
10. The antimicrobial composition according to claim 8,
the bicarbonate is sodium bicarbonate or potassium bicarbonate.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2017200181 | 2017-10-16 | ||
| JP2017-200181 | 2017-10-16 | ||
| PCT/JP2018/038371 WO2019078173A1 (en) | 2017-10-16 | 2018-10-15 | Antimicrobial composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111225564A true CN111225564A (en) | 2020-06-02 |
Family
ID=66173281
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201880067226.XA Pending CN111225564A (en) | 2017-10-16 | 2018-10-15 | Antibacterial composition |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JP7298908B2 (en) |
| CN (1) | CN111225564A (en) |
| WO (1) | WO2019078173A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113995744A (en) * | 2021-10-13 | 2022-02-01 | 温州肯恩大学 | Composition and antibacterial application thereof |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2020218458A1 (en) * | 2019-04-24 | 2020-10-29 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102612320A (en) * | 2009-11-10 | 2012-07-25 | 株式会社川上 | Virus-inactivating agent |
| CN102802448A (en) * | 2009-06-26 | 2012-11-28 | 株式会社川上 | Sterilizer For Foods |
| JP2014014801A (en) * | 2012-07-11 | 2014-01-30 | Tokyo Univ Of Agriculture & Technology | Sterilized water, antiviral agent, washing water for sterilization in perishable food processing system, and insecticide for poultry |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08154640A (en) * | 1994-12-08 | 1996-06-18 | Nippon Oil & Fats Co Ltd | Antimicrobial agent for food |
| JPH08256703A (en) * | 1995-03-22 | 1996-10-08 | Torigoe Seifun Kk | Quality improver for food |
| JP3694091B2 (en) * | 1996-03-12 | 2005-09-14 | 要次郎 山田 | Preparation of organic acid mineral solution antibacterial agent for bacterial growth inhibition |
| JPH11164675A (en) * | 1997-12-05 | 1999-06-22 | Asama Kasei Kk | Preservative for food and preservation of food |
| JPH11290044A (en) * | 1998-04-16 | 1999-10-26 | Sankyo Foods Kk | Calcium solution preparation |
| JP2001346556A (en) * | 2000-06-06 | 2001-12-18 | Fuso Chemical Co Ltd | Fruit acid-containing drink |
| JP2002119241A (en) * | 2000-10-13 | 2002-04-23 | Riken Vitamin Co Ltd | Vinegar composition |
| JP2003038146A (en) * | 2001-07-30 | 2003-02-12 | Chisso Corp | Food preservative, food containing the same, and method for preparing vegetable |
| JP4630253B2 (en) * | 2006-09-29 | 2011-02-09 | 株式会社日清製粉グループ本社 | Method for sterilizing vegetables and fruits |
| JP4774072B2 (en) * | 2008-03-18 | 2011-09-14 | アンデス電気株式会社 | Antibacterial and antifungal composition and its application |
| JP5828383B2 (en) * | 2011-07-26 | 2015-12-02 | 国立大学法人広島大学 | Intraoral disinfectant and method for producing the same |
| JP5882792B2 (en) * | 2012-03-02 | 2016-03-09 | 千葉製粉株式会社 | Preparations for processing marine products or livestock meat, and methods for processing marine products or livestock meat using the same |
| JP2014024780A (en) * | 2012-07-25 | 2014-02-06 | Shunichiro Kiuchi | Germicide |
| JP6506524B2 (en) * | 2014-10-09 | 2019-04-24 | 小泉 國雄 | Deodorizing method with deodorizing stock solution using calcium ion complexing solution |
| JP6781976B2 (en) * | 2016-06-28 | 2020-11-11 | 株式会社日本抗菌総合研究所 | Powder cleaning agent |
-
2018
- 2018-10-15 JP JP2019549277A patent/JP7298908B2/en active Active
- 2018-10-15 WO PCT/JP2018/038371 patent/WO2019078173A1/en active Application Filing
- 2018-10-15 CN CN201880067226.XA patent/CN111225564A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102802448A (en) * | 2009-06-26 | 2012-11-28 | 株式会社川上 | Sterilizer For Foods |
| CN102612320A (en) * | 2009-11-10 | 2012-07-25 | 株式会社川上 | Virus-inactivating agent |
| JP2014014801A (en) * | 2012-07-11 | 2014-01-30 | Tokyo Univ Of Agriculture & Technology | Sterilized water, antiviral agent, washing water for sterilization in perishable food processing system, and insecticide for poultry |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113995744A (en) * | 2021-10-13 | 2022-02-01 | 温州肯恩大学 | Composition and antibacterial application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2019078173A1 (en) | 2020-11-05 |
| JP7298908B2 (en) | 2023-06-27 |
| WO2019078173A1 (en) | 2019-04-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2001263437B2 (en) | Biocidal cleaner composition | |
| CN107466207A (en) | Antimicrobial compositions | |
| CN102834012B (en) | Disinfection aid for ozone disinfection and method for ozone disinfection | |
| JPH06508612A (en) | Mixed carboxylic acid sanitary agent | |
| NZ545932A (en) | Anhydrous silver dihydrogen citrate compositions | |
| CN105193645B (en) | A kind of disinfection hand cleanser | |
| JP2013180956A (en) | Bactericidal agent composition | |
| BR112013012458A2 (en) | stable and concentrated composition of an aqueous preservative of dehydroacetic acid (dha) and methylisothiazolinone (mit | |
| JP4774072B2 (en) | Antibacterial and antifungal composition and its application | |
| CN111225564A (en) | Antibacterial composition | |
| JP7096637B2 (en) | Disinfectant composition and cleaning sterilization method | |
| TWI567097B (en) | A preparation method of water soluble antimicrobial polyacrylate silver salt | |
| CN113854290A (en) | Long-acting lasting biguanide compound disinfectant and preparation method thereof | |
| CN107683325B (en) | Liquid detergent composition for clothing | |
| CN105087180A (en) | Antibacterial and anti-mildew cleaning and treating agent for towels | |
| CN102302033A (en) | Preparation and application of compounded disinfection atomization agent | |
| KR101591410B1 (en) | Effervescent Compositions Having Reinforced Stability and Preparing Methods thereof | |
| CN108676628A (en) | A kind of fabrics disinfectant detergent | |
| JPH1161639A (en) | Antimicrobial finishing agent for washing | |
| CN110313489B (en) | Anti-corrosion sterilization type wet tissue and preparation method and application thereof | |
| JP4638348B2 (en) | Food grade disinfecting composition | |
| JP7073436B2 (en) | Cleaning composition | |
| JPH09143010A (en) | Antibacterial agent | |
| JPH10237320A (en) | Antimicrobial resin composition and antimicrobial resin molded product using the same | |
| CN104082293B (en) | A kind of composite alcohol sterilizing agent and its preparation method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20200602 |