CN111183220B - 用于聚糖分析的工具 - Google Patents

用于聚糖分析的工具 Download PDF

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Publication number
CN111183220B
CN111183220B CN201880050240.9A CN201880050240A CN111183220B CN 111183220 B CN111183220 B CN 111183220B CN 201880050240 A CN201880050240 A CN 201880050240A CN 111183220 B CN111183220 B CN 111183220B
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Chinese (zh)
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CN111183220A (zh
Inventor
弗雷德里克·里奥
罗尔夫·卢德
史蒂芬·比约克
马林·梅贾尔
弗雷德里克·奥尔森
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Genovis AB
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Genovis AB
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Priority claimed from GBGB1708471.6A external-priority patent/GB201708471D0/en
Priority claimed from GBGB1708476.5A external-priority patent/GB201708476D0/en
Priority claimed from GBGB1806655.5A external-priority patent/GB201806655D0/en
Application filed by Genovis AB filed Critical Genovis AB
Publication of CN111183220A publication Critical patent/CN111183220A/zh
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/24057—O-Sialoglycoprotein endopeptidase (3.4.24.57), i.e. glycoprotease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/952—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from bacteria

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
CN201880050240.9A 2017-05-26 2018-05-25 用于聚糖分析的工具 Active CN111183220B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GBGB1708471.6A GB201708471D0 (en) 2017-05-26 2017-05-26 Polypeptide
GBGB1708476.5A GB201708476D0 (en) 2017-05-26 2017-05-26 Tools for glycan analysis
GB1708471.6 2017-05-26
GB1708476.5 2017-05-26
GBGB1806655.5A GB201806655D0 (en) 2018-04-24 2018-04-24 Polypeptide
GB1806655.5 2018-04-24
PCT/EP2018/063833 WO2018215657A1 (en) 2017-05-26 2018-05-25 Enzymes for glycan analysis

Publications (2)

Publication Number Publication Date
CN111183220A CN111183220A (zh) 2020-05-19
CN111183220B true CN111183220B (zh) 2024-03-22

Family

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Family Applications (2)

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CN201880050240.9A Active CN111183220B (zh) 2017-05-26 2018-05-25 用于聚糖分析的工具
CN201880050251.7A Active CN111183221B (zh) 2017-05-26 2018-05-25 用于o-糖蛋白的蛋白酶和结合多肽

Family Applications After (1)

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CN201880050251.7A Active CN111183221B (zh) 2017-05-26 2018-05-25 用于o-糖蛋白的蛋白酶和结合多肽

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US (3) US12448614B2 (https=)
EP (2) EP3630967B8 (https=)
JP (3) JP7195008B2 (https=)
KR (2) KR102608876B1 (https=)
CN (2) CN111183220B (https=)
AU (2) AU2018272984B2 (https=)
CA (2) CA3063815A1 (https=)
DK (2) DK3630967T3 (https=)
ES (2) ES2986910T3 (https=)
FI (2) FI3630968T3 (https=)
IL (2) IL270949B2 (https=)
PL (2) PL3630968T3 (https=)
PT (2) PT3630968T (https=)
WO (2) WO2018215656A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111183220B (zh) 2017-05-26 2024-03-22 杰诺维斯公司 用于聚糖分析的工具
CN114258431A (zh) * 2019-07-03 2022-03-29 帕利昂制药有限公司 重组人唾液酸酶、唾液酸酶融合蛋白及其使用方法
CN112795583A (zh) * 2020-11-16 2021-05-14 上海大学 重组唾液酸外切酶的制备方法、表达基因、重组表达载体及构建方法
US20250051821A1 (en) * 2021-12-15 2025-02-13 Danisco Us Inc. Compositions and methods involving proteases specific for mannose-modified proteins
EP4627340A1 (en) * 2022-11-28 2025-10-08 Amgen Inc. Method of processing etanercept
US20260092921A1 (en) 2024-09-27 2026-04-02 Roche Diagnostics Gmbh Mutated neuroaminidase

Citations (1)

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Publication number Priority date Publication date Assignee Title
CN101426906A (zh) * 2004-09-10 2009-05-06 房芳 一类新颖的以蛋白质为基础的治疗用分子

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US6720165B2 (en) 2001-06-14 2004-04-13 Zyomix, Inc. Methods for making antibody fragments and compositions resulting therefrom
GB0624874D0 (en) 2006-12-13 2007-01-24 Hansa Medical Ab Treatment
WO2009129086A2 (en) 2008-04-18 2009-10-22 New England Biolabs, Inc. Endoglycosidases that cleave o-linked glycans
EP2166085A1 (en) 2008-07-16 2010-03-24 Suomen Punainen Risti Veripalvelu Divalent modified cells
WO2010111674A2 (en) * 2009-03-27 2010-09-30 Life Technologies Corporation Methods and apparatus for single molecule sequencing using energy transfer detection
GB201115841D0 (en) 2011-09-13 2011-10-26 Genovis Ab Protein and method
GB201316744D0 (en) 2013-09-20 2013-11-06 Genovis Ab Method
WO2016003795A1 (en) 2014-07-02 2016-01-07 New England Biolabs, Inc. Universal n-glycan binding reagent
WO2017052433A1 (en) 2015-09-24 2017-03-30 Saab Ab A modular fluid actuator system
AU2017214441B2 (en) 2016-02-04 2021-08-19 Genovis Ab New Streptococcal proteases
CN111183220B (zh) * 2017-05-26 2024-03-22 杰诺维斯公司 用于聚糖分析的工具

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101426906A (zh) * 2004-09-10 2009-05-06 房芳 一类新颖的以蛋白质为基础的治疗用分子

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Biochemical characterisation of the neuraminidase pool of the human gut symbiont Akkermansia muciniphila;Kun Huang et al.;《Carbohydrate Research》;第415卷;第16页图1 *
Identification and Characterization of Protein Glycosylation using Specific Endo- and Exoglycosidases;Magnelli, P.E et al.;《J. Vis. Exp.》;第58卷;第1页摘要 *
糖蛋白的研究进展;郭慧等;《生物技术通报》(第undefined期);第16-19页 *

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Publication number Publication date
CN111183221B (zh) 2024-04-09
US12448614B2 (en) 2025-10-21
EP3630967A1 (en) 2020-04-08
US20230212543A1 (en) 2023-07-06
KR102608876B1 (ko) 2023-11-30
DK3630967T3 (da) 2024-08-19
JP2023103233A (ja) 2023-07-26
AU2018272984B2 (en) 2024-05-23
EP3630968B1 (en) 2024-05-29
FI3630967T3 (fi) 2024-08-12
KR102609790B1 (ko) 2023-12-04
US11584922B2 (en) 2023-02-21
FI3630968T3 (fi) 2024-07-24
PT3630968T (pt) 2024-07-30
WO2018215656A1 (en) 2018-11-29
AU2018272984A1 (en) 2019-12-05
CN111183220A (zh) 2020-05-19
AU2018272400A1 (en) 2019-12-05
PL3630967T3 (pl) 2024-11-18
JP7195008B2 (ja) 2022-12-23
US20200172889A1 (en) 2020-06-04
EP3630968A1 (en) 2020-04-08
WO2018215656A9 (en) 2019-03-14
WO2018215657A1 (en) 2018-11-29
PT3630967T (pt) 2024-08-21
ES2986910T3 (es) 2024-11-13
WO2018215657A9 (en) 2019-03-14
AU2018272400B2 (en) 2024-06-13
CA3063828A1 (en) 2018-11-29
ES2986557T3 (es) 2024-11-11
IL270950B2 (en) 2025-06-01
EP3630967B1 (en) 2024-06-12
CN111183221A (zh) 2020-05-19
KR20200010322A (ko) 2020-01-30
IL270949B2 (en) 2025-06-01
IL270949A (en) 2020-01-30
CA3063815A1 (en) 2018-11-29
IL270950A (en) 2020-01-30
JP7557896B2 (ja) 2024-09-30
IL270950B1 (en) 2025-02-01
US12529044B2 (en) 2026-01-20
KR20200011955A (ko) 2020-02-04
IL270949B1 (en) 2025-02-01
PL3630968T3 (pl) 2024-10-07
DK3630968T3 (da) 2024-07-29
JP2020522242A (ja) 2020-07-30
EP3630967B8 (en) 2024-07-17
EP3630968B8 (en) 2024-07-03
US20200087643A1 (en) 2020-03-19
JP2020521460A (ja) 2020-07-27

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