DK3630967T3 - Protease og bindingspolypeptid for o-glycoproteiner - Google Patents

Protease og bindingspolypeptid for o-glycoproteiner Download PDF

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Publication number
DK3630967T3
DK3630967T3 DK18728576.2T DK18728576T DK3630967T3 DK 3630967 T3 DK3630967 T3 DK 3630967T3 DK 18728576 T DK18728576 T DK 18728576T DK 3630967 T3 DK3630967 T3 DK 3630967T3
Authority
DK
Denmark
Prior art keywords
glycoproteins
protease
binding polypeptide
polypeptide
binding
Prior art date
Application number
DK18728576.2T
Other languages
Danish (da)
English (en)
Inventor
Fredrik Leo
Stephan Bjork
Malin Mejare
Fredrik Olsson
Rolf Lood-Alayón
Original Assignee
Genovis Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1708471.6A external-priority patent/GB201708471D0/en
Priority claimed from GBGB1708476.5A external-priority patent/GB201708476D0/en
Priority claimed from GBGB1806655.5A external-priority patent/GB201806655D0/en
Application filed by Genovis Ab filed Critical Genovis Ab
Application granted granted Critical
Publication of DK3630967T3 publication Critical patent/DK3630967T3/da

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24Metalloendopeptidases (3.4.24)
    • C12Y304/24057O-Sialoglycoprotein endopeptidase (3.4.24.57), i.e. glycoprotease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/924Hydrolases (3) acting on glycosyl compounds (3.2)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/948Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/952Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from bacteria

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
DK18728576.2T 2017-05-26 2018-05-25 Protease og bindingspolypeptid for o-glycoproteiner DK3630967T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB1708471.6A GB201708471D0 (en) 2017-05-26 2017-05-26 Polypeptide
GBGB1708476.5A GB201708476D0 (en) 2017-05-26 2017-05-26 Tools for glycan analysis
GBGB1806655.5A GB201806655D0 (en) 2018-04-24 2018-04-24 Polypeptide
PCT/EP2018/063832 WO2018215656A1 (en) 2017-05-26 2018-05-25 Protease and binding polypeptide for o-glycoproteins

Publications (1)

Publication Number Publication Date
DK3630967T3 true DK3630967T3 (da) 2024-08-19

Family

ID=62492612

Family Applications (2)

Application Number Title Priority Date Filing Date
DK18728576.2T DK3630967T3 (da) 2017-05-26 2018-05-25 Protease og bindingspolypeptid for o-glycoproteiner
DK18728577.0T DK3630968T3 (da) 2017-05-26 2018-05-25 Enzymer til glycananalyse

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK18728577.0T DK3630968T3 (da) 2017-05-26 2018-05-25 Enzymer til glycananalyse

Country Status (14)

Country Link
US (3) US12448614B2 (https=)
EP (2) EP3630967B8 (https=)
JP (3) JP7195008B2 (https=)
KR (2) KR102608876B1 (https=)
CN (2) CN111183220B (https=)
AU (2) AU2018272984B2 (https=)
CA (2) CA3063815A1 (https=)
DK (2) DK3630967T3 (https=)
ES (2) ES2986910T3 (https=)
FI (2) FI3630968T3 (https=)
IL (2) IL270949B2 (https=)
PL (2) PL3630968T3 (https=)
PT (2) PT3630968T (https=)
WO (2) WO2018215656A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111183220B (zh) 2017-05-26 2024-03-22 杰诺维斯公司 用于聚糖分析的工具
CN114258431A (zh) * 2019-07-03 2022-03-29 帕利昂制药有限公司 重组人唾液酸酶、唾液酸酶融合蛋白及其使用方法
CN112795583A (zh) * 2020-11-16 2021-05-14 上海大学 重组唾液酸外切酶的制备方法、表达基因、重组表达载体及构建方法
US20250051821A1 (en) * 2021-12-15 2025-02-13 Danisco Us Inc. Compositions and methods involving proteases specific for mannose-modified proteins
EP4627340A1 (en) * 2022-11-28 2025-10-08 Amgen Inc. Method of processing etanercept
US20260092921A1 (en) 2024-09-27 2026-04-02 Roche Diagnostics Gmbh Mutated neuroaminidase

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6720165B2 (en) 2001-06-14 2004-04-13 Zyomix, Inc. Methods for making antibody fragments and compositions resulting therefrom
US7807174B2 (en) * 2002-11-22 2010-10-05 Nexbio, Inc. Class of therapeutic protein based molecules
GB0624874D0 (en) 2006-12-13 2007-01-24 Hansa Medical Ab Treatment
WO2009129086A2 (en) 2008-04-18 2009-10-22 New England Biolabs, Inc. Endoglycosidases that cleave o-linked glycans
EP2166085A1 (en) 2008-07-16 2010-03-24 Suomen Punainen Risti Veripalvelu Divalent modified cells
WO2010111674A2 (en) * 2009-03-27 2010-09-30 Life Technologies Corporation Methods and apparatus for single molecule sequencing using energy transfer detection
GB201115841D0 (en) 2011-09-13 2011-10-26 Genovis Ab Protein and method
GB201316744D0 (en) 2013-09-20 2013-11-06 Genovis Ab Method
WO2016003795A1 (en) 2014-07-02 2016-01-07 New England Biolabs, Inc. Universal n-glycan binding reagent
WO2017052433A1 (en) 2015-09-24 2017-03-30 Saab Ab A modular fluid actuator system
AU2017214441B2 (en) 2016-02-04 2021-08-19 Genovis Ab New Streptococcal proteases
CN111183220B (zh) * 2017-05-26 2024-03-22 杰诺维斯公司 用于聚糖分析的工具

Also Published As

Publication number Publication date
CN111183221B (zh) 2024-04-09
US12448614B2 (en) 2025-10-21
EP3630967A1 (en) 2020-04-08
US20230212543A1 (en) 2023-07-06
KR102608876B1 (ko) 2023-11-30
JP2023103233A (ja) 2023-07-26
AU2018272984B2 (en) 2024-05-23
EP3630968B1 (en) 2024-05-29
FI3630967T3 (fi) 2024-08-12
KR102609790B1 (ko) 2023-12-04
US11584922B2 (en) 2023-02-21
FI3630968T3 (fi) 2024-07-24
PT3630968T (pt) 2024-07-30
WO2018215656A1 (en) 2018-11-29
AU2018272984A1 (en) 2019-12-05
CN111183220A (zh) 2020-05-19
AU2018272400A1 (en) 2019-12-05
PL3630967T3 (pl) 2024-11-18
JP7195008B2 (ja) 2022-12-23
US20200172889A1 (en) 2020-06-04
EP3630968A1 (en) 2020-04-08
WO2018215656A9 (en) 2019-03-14
WO2018215657A1 (en) 2018-11-29
PT3630967T (pt) 2024-08-21
ES2986910T3 (es) 2024-11-13
WO2018215657A9 (en) 2019-03-14
AU2018272400B2 (en) 2024-06-13
CA3063828A1 (en) 2018-11-29
ES2986557T3 (es) 2024-11-11
IL270950B2 (en) 2025-06-01
EP3630967B1 (en) 2024-06-12
CN111183221A (zh) 2020-05-19
KR20200010322A (ko) 2020-01-30
IL270949B2 (en) 2025-06-01
IL270949A (en) 2020-01-30
CN111183220B (zh) 2024-03-22
CA3063815A1 (en) 2018-11-29
IL270950A (en) 2020-01-30
JP7557896B2 (ja) 2024-09-30
IL270950B1 (en) 2025-02-01
US12529044B2 (en) 2026-01-20
KR20200011955A (ko) 2020-02-04
IL270949B1 (en) 2025-02-01
PL3630968T3 (pl) 2024-10-07
DK3630968T3 (da) 2024-07-29
JP2020522242A (ja) 2020-07-30
EP3630967B8 (en) 2024-07-17
EP3630968B8 (en) 2024-07-03
US20200087643A1 (en) 2020-03-19
JP2020521460A (ja) 2020-07-27

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