CN111132715B - 微导管 - Google Patents
微导管 Download PDFInfo
- Publication number
- CN111132715B CN111132715B CN201880051040.5A CN201880051040A CN111132715B CN 111132715 B CN111132715 B CN 111132715B CN 201880051040 A CN201880051040 A CN 201880051040A CN 111132715 B CN111132715 B CN 111132715B
- Authority
- CN
- China
- Prior art keywords
- microcatheter
- distal
- section
- outer layer
- shore hardness
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L27/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers
- C08L27/02—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers not modified by chemical after-treatment
- C08L27/12—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers not modified by chemical after-treatment containing fluorine atoms
- C08L27/18—Homopolymers or copolymers or tetrafluoroethene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/02—Inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/04—Macromolecular materials
- A61L29/041—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/04—Macromolecular materials
- A61L29/049—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L29/126—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
- A61L29/18—Materials at least partially X-ray or laser opaque
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0009—Making of catheters or other medical or surgical tubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0009—Making of catheters or other medical or surgical tubes
- A61M25/0012—Making of catheters or other medical or surgical tubes with embedded structures, e.g. coils, braids, meshes, strands or radiopaque coils
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M25/0045—Catheters; Hollow probes characterised by structural features multi-layered, e.g. coated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M25/005—Catheters; Hollow probes characterised by structural features with embedded materials for reinforcement, e.g. wires, coils, braids
- A61M25/0053—Catheters; Hollow probes characterised by structural features with embedded materials for reinforcement, e.g. wires, coils, braids having a variable stiffness along the longitudinal axis, e.g. by varying the pitch of the coil or braid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
- A61M25/0108—Steering means as part of the catheter or advancing means; Markers for positioning using radio-opaque or ultrasound markers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C61/00—Shaping by liberation of internal stresses; Making preforms having internal stresses; Apparatus therefor
- B29C61/02—Thermal shrinking
- B29C61/025—Thermal shrinking for the production of hollow or tubular articles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C63/00—Lining or sheathing, i.e. applying preformed layers or sheathings of plastics; Apparatus therefor
- B29C63/0017—Lining or sheathing, i.e. applying preformed layers or sheathings of plastics; Apparatus therefor characterised by the choice of the material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C63/00—Lining or sheathing, i.e. applying preformed layers or sheathings of plastics; Apparatus therefor
- B29C63/0065—Heat treatment
- B29C63/0069—Heat treatment of tubular articles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C63/00—Lining or sheathing, i.e. applying preformed layers or sheathings of plastics; Apparatus therefor
- B29C63/18—Lining or sheathing, i.e. applying preformed layers or sheathings of plastics; Apparatus therefor using tubular layers or sheathings
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L75/00—Compositions of polyureas or polyurethanes; Compositions of derivatives of such polymers
- C08L75/04—Polyurethanes
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L77/00—Compositions of polyamides obtained by reactions forming a carboxylic amide link in the main chain; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
- A61M2025/0042—Microcatheters, cannula or the like having outside diameters around 1 mm or less
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2675/00—Use of PU, i.e. polyureas or polyurethanes or derivatives thereof, for preformed parts, e.g. for inserts
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2031/00—Other particular articles
- B29L2031/753—Medical equipment; Accessories therefor
- B29L2031/7542—Catheters
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Manufacturing & Machinery (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Thermal Sciences (AREA)
- Materials Engineering (AREA)
- Composite Materials (AREA)
- Inorganic Chemistry (AREA)
- Optics & Photonics (AREA)
- Materials For Medical Uses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211403650.1A CN115715826A (zh) | 2017-08-09 | 2018-08-08 | 微导管 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762542960P | 2017-08-09 | 2017-08-09 | |
| US62/542,960 | 2017-08-09 | ||
| PCT/IL2018/050882 WO2019030761A1 (en) | 2017-08-09 | 2018-08-08 | microcatheter |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211403650.1A Division CN115715826A (zh) | 2017-08-09 | 2018-08-08 | 微导管 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN111132715A CN111132715A (zh) | 2020-05-08 |
| CN111132715B true CN111132715B (zh) | 2023-04-07 |
Family
ID=65270944
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201880051040.5A Active CN111132715B (zh) | 2017-08-09 | 2018-08-08 | 微导管 |
| CN202211403650.1A Pending CN115715826A (zh) | 2017-08-09 | 2018-08-08 | 微导管 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211403650.1A Pending CN115715826A (zh) | 2017-08-09 | 2018-08-08 | 微导管 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11471646B2 (enExample) |
| EP (1) | EP3664881A4 (enExample) |
| JP (2) | JP7530289B2 (enExample) |
| KR (1) | KR102705634B1 (enExample) |
| CN (2) | CN111132715B (enExample) |
| IL (1) | IL272295B2 (enExample) |
| WO (1) | WO2019030761A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011130107A2 (en) | 2010-04-16 | 2011-10-20 | Surgivision, Inc. | Mri surgical systems including mri-compatible surgical cannulae for transferring a substance to and/or from a patient |
| WO2017142698A1 (en) | 2016-02-17 | 2017-08-24 | MRI Interventions, Inc. | Intrabody surgical fluid transfer assemblies with adjustable exposed cannula to needle tip length, related systems and methods |
| EP3781074A1 (en) | 2018-05-09 | 2021-02-24 | ClearPoint Neuro, Inc. | Mri compatible intrabody fluid transfer systems and related devices and methods |
| US11253237B2 (en) | 2018-05-09 | 2022-02-22 | Clearpoint Neuro, Inc. | MRI compatible intrabody fluid transfer systems and related devices and methods |
| US11684750B2 (en) | 2019-10-08 | 2023-06-27 | Clearpoint Neuro, Inc. | Extension tube assembly and related medical fluid transfer systems and methods |
| CN111135425B (zh) * | 2020-03-06 | 2021-09-10 | 广东博迈医疗科技股份有限公司 | 一种医用微导管 |
| US11951026B2 (en) * | 2020-06-30 | 2024-04-09 | DePuy Synthes Products, Inc. | Implantable medical device detachment system with flexible braid section |
| IL276416B (en) * | 2020-07-30 | 2021-08-31 | Accurate Medical Therapeutics Ltd | Catheter for embolization to administer large globules |
| IL276418B (en) * | 2020-07-30 | 2022-06-01 | Accurate Medical Therapeutics Ltd | Embolization catheter for administering spheroids to peripheral blood vessels |
| CN113384795A (zh) * | 2021-05-26 | 2021-09-14 | 南京康友医疗科技有限公司 | 一种微导管 |
| WO2023014403A1 (en) * | 2021-08-03 | 2023-02-09 | Verivas Solutions Inc. | Vascular access system |
| USD1071148S1 (en) * | 2022-10-19 | 2025-04-15 | Accurate Medical Therapeutics Ltd. | Embolization microcatheter for delivery of beads to peripheral vessels |
| KR20250099805A (ko) | 2023-12-26 | 2025-07-03 | 주식회사 바스플렉스 | 마이크로카테터 허브 사출용 보강튜브 어셈블리 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996038194A2 (en) * | 1995-06-01 | 1996-12-05 | Scimed Life Systems, Inc. | Flow assisted catheter |
| JP3915862B2 (ja) * | 2000-02-09 | 2007-05-16 | テルモ株式会社 | カテーテル |
| US20020156459A1 (en) * | 2001-04-20 | 2002-10-24 | Scimed Life Systems, Inc | Microcatheter with improved distal tip and transitions |
| US6638245B2 (en) * | 2001-06-26 | 2003-10-28 | Concentric Medical, Inc. | Balloon catheter |
| WO2003064909A1 (en) | 2002-01-25 | 2003-08-07 | Natvar Holdings, Inc. | Co-extruded tubing |
| CA2501147A1 (en) | 2002-10-10 | 2004-04-22 | Micro Therapeutics, Inc. | Wire braid-reinforced microcatheter |
| CN101001658A (zh) * | 2004-08-10 | 2007-07-18 | 株式会社钟化 | 医疗用导管及其制造方法 |
| US7306585B2 (en) * | 2004-09-30 | 2007-12-11 | Engineering Resources Group, Inc. | Guide catheter |
| WO2007070544A2 (en) * | 2005-12-13 | 2007-06-21 | Cook Incorporated | Implantable medical device using palladium |
| US7905877B1 (en) * | 2006-05-12 | 2011-03-15 | Micrus Design Technology, Inc. | Double helix reinforced catheter |
| AU2008292840B2 (en) | 2007-08-30 | 2011-09-15 | Syncro Medical Innovations, Inc. | Guided catheter with removable magnetic guide |
| EP2145895B1 (en) * | 2008-07-08 | 2013-10-30 | Commissariat à l'Énergie Atomique et aux Énergies Alternatives | Process for the manufacturing of glycochips |
| US8684963B2 (en) | 2012-07-05 | 2014-04-01 | Abbott Cardiovascular Systems Inc. | Catheter with a dual lumen monolithic shaft |
| US20160256216A1 (en) * | 2013-03-11 | 2016-09-08 | Medtronic Ardian Luxembourg S.A.R.L. | Catheter apparatuses for pulmonary artery neuromodulation |
| WO2014144431A1 (en) * | 2013-03-15 | 2014-09-18 | Abbott Cardiovascular Systems Inc. | Catheter shaft and method of forming same |
| JP2017517494A (ja) * | 2014-04-17 | 2017-06-29 | ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. | 治療用温熱処置のための機器及び方法 |
| JP6372173B2 (ja) | 2014-06-03 | 2018-08-15 | 住友ベークライト株式会社 | 医療機器 |
| US10780246B2 (en) * | 2014-09-12 | 2020-09-22 | Callisyn Biomedical, Inc. | Vascular microcatheter |
| CN107007922A (zh) | 2017-03-28 | 2017-08-04 | 广州启骏生物科技有限公司 | 一种鼻窦球囊扩张和治疗装置 |
-
2018
- 2018-08-08 EP EP18844973.0A patent/EP3664881A4/en active Pending
- 2018-08-08 JP JP2020505474A patent/JP7530289B2/ja active Active
- 2018-08-08 CN CN201880051040.5A patent/CN111132715B/zh active Active
- 2018-08-08 IL IL272295A patent/IL272295B2/en unknown
- 2018-08-08 US US16/634,344 patent/US11471646B2/en active Active
- 2018-08-08 CN CN202211403650.1A patent/CN115715826A/zh active Pending
- 2018-08-08 WO PCT/IL2018/050882 patent/WO2019030761A1/en not_active Ceased
- 2018-08-08 KR KR1020207003557A patent/KR102705634B1/ko active Active
-
2023
- 2023-03-01 JP JP2023031388A patent/JP2023071850A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL272295A (en) | 2020-03-31 |
| KR20200039681A (ko) | 2020-04-16 |
| IL272295B1 (en) | 2024-10-01 |
| US11471646B2 (en) | 2022-10-18 |
| WO2019030761A1 (en) | 2019-02-14 |
| KR102705634B1 (ko) | 2024-09-11 |
| CN111132715A (zh) | 2020-05-08 |
| EP3664881A4 (en) | 2021-05-26 |
| JP2020530323A (ja) | 2020-10-22 |
| EP3664881A1 (en) | 2020-06-17 |
| BR112020002723A2 (pt) | 2020-07-28 |
| JP2023071850A (ja) | 2023-05-23 |
| CN115715826A (zh) | 2023-02-28 |
| JP7530289B2 (ja) | 2024-08-07 |
| IL272295B2 (en) | 2025-02-01 |
| US20200230355A1 (en) | 2020-07-23 |
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Legal Events
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |