CN111053844A

CN111053844A - Oral granule for treating psoriasis

Info

Publication number: CN111053844A
Application number: CN202010020856.0A
Authority: CN
Inventors: 高欣
Original assignee: Shanghai Yizhike Biomedical Technology Co Ltd
Current assignee: Shanghai Yizhike Biomedical Technology Co Ltd
Priority date: 2020-01-09
Filing date: 2020-01-09
Publication date: 2020-04-24

Abstract

The invention discloses an oral granule for treating psoriasis, which is characterized in that the medicine is prepared by taking the following traditional Chinese medicines as raw materials in parts by weight:

Description

Oral granule for treating psoriasis

Technical Field

The invention relates to the technical field of traditional Chinese medicines, in particular to an oral granule for treating psoriasis.

Background

Psoriasis, a common chronic, easily relapsing inflammatory skin disease with characteristic skin lesions. The early stage is inflammatory red papule, about millet to mung bean in size, and then gradually expands or fuses into brownish red plaque with clear boundary, inflammatory red halo around the plaque, obvious substrate infiltration, and multiple layers of dry grey-white or silvery-white scales on the surface. The surface scale is scraped off slightly, and a layer of pale red and bright semitransparent film is gradually exposed, which is called the film phenomenon. When the film is scraped off, a small bleeding spot appears, which is called a spot bleeding phenomenon. White scales, shiny films and punctate bleeding are important features for diagnosing psoriasis, called triple features. Psoriasis vulgaris lesions can be roughly divided into three periods from occurrence to eventual regression: the progressive stage, the stationary stage and the retrogradation stage are carried out, inflammatory red papules are formed at the beginning, the sizes of the papules are about from millet grains to mung beans, the papules are gradually enlarged or fused into brownish red plaques later, the boundaries are clear, inflammatory halos are formed around the papules, the substrate is obviously infiltrated, and the surfaces of the papules are covered with multiple layers of dry grey-white or silvery-white scales. The surface scale is scraped off slightly, and a layer of pale red and bright semitransparent film is gradually exposed, which is called the film phenomenon. When the film is scraped off, a small bleeding spot appears, which is called a spot bleeding phenomenon. White scales, shiny films and punctate bleeding are important features for diagnosing psoriasis, called triple features. Skin lesion morphology: drop, coin, map, ring, strip, hair-growing, seborrheic dermatitis, eczema, oyster shell, lichen planus, chronic pachynsis, wart, etc.

Psoriasis is currently treated in three degrees, mild, moderate and severe: mild, 10% area of skin damage. The mild psoriasis is only treated by external medicines, the moderate and severe psoriasis is treated by combined therapy, including external medicines, internal medicines and physical therapy, the medicines are mostly medicines with large irritation, such as antibiotics, biological agents and the like, which are used for treating the mild psoriasis, so that the medicines are harmful to human bodies, and the traditional Chinese medicine therapy has the characteristics of small side effect, good anti-recurrence rate effect, stable disease state and no diffusion, so that the traditional Chinese medicine therapy is quickly applied and popularized in the field of psoriasis diseases. At present, a traditional Chinese medicine formula for treating psoriasis diseases is researched in China and achieves certain effect, for example, the invention of application No. CN201710281144.2, namely the traditional Chinese medicine composition for treating psoriasis, discloses a traditional Chinese medicine composition for treating psoriasis, which comprises the following raw materials in parts by weight: 3-8 parts of honeysuckle, 2-6 parts of divaricate saposhnikovia root, 3-8 parts of pawpaw, 2-6 parts of coix seed, 3-8 parts of akebia stem, 1-5 parts of angelica sinensis, 3-8 parts of abalone shell, 1-5 parts of ginseng, 3-8 parts of cortex dictamni, 1-5 parts of Chinese little snake grass, 2-6 parts of angelica dahurica, 1-5 parts of liquorice and 2-6 parts of fructus kochiae. However, the traditional Chinese medicine formula in the prior art is unreasonable, and the raw material components are inappropriate, so that the treatment effect of the psoriasis diseases is not obvious at present, and the improvement rate is low.

Disclosure of Invention

In view of the above, the invention provides an oral granule for treating psoriasis, which has the characteristics of good curative effect, quick response, no side effect, difficult relapse and the like.

In order to achieve the purpose, the invention provides the following technical scheme:

the oral granule for treating psoriasis is characterized in that the medicine is prepared by taking the following traditional Chinese medicines as raw materials in parts by weight:

preferably, in the oral granule for treating psoriasis, the medicine is prepared from the following traditional Chinese medicines in parts by weight:

the pharmacology of the traditional Chinese medicine is as follows:

the honeysuckle flower is cold in nature and sweet in taste, enters lung, heart and stomach channels, has the effects of clearing heat and removing toxicity, resisting inflammation, tonifying deficiency and treating wind, and is mainly used for treating diseases such as distending pain, fever due to epidemic febrile disease, toxic heat, carbuncle and ulcer, tumor and the like. It has therapeutic effects on dizziness, thirst, hyperhidrosis, vexation, enteritis, bacillary dysentery, measles, pneumonia, encephalitis B, epidemic encephalitis, acute mastitis, septicemia, appendicitis, skin infection, carbuncle, furuncle, erysipelas, parotitis, and suppurative tonsillitis.

The purslane has cold and cool property, has three efficacies of detoxification, inflammation diminishing and heat removing, and can also improve eyesight, reduce blood fat, enter liver meridian, cool blood and reduce liver fire.

Boswellia carteri enters heart, liver and spleen meridians. It can be used for treating thoracic obstruction, heart pain, epigastric pain, dysmenorrhea, amenorrhea, puerperal blood stasis, abdominal pain, rheumatic arthralgia, spasm of muscles and tendons, traumatic injury, carbuncle, swelling, sore, and ulcer.

Herba Menthae is a common Chinese medicine, and young tender stem tip can be eaten as vegetable, and whole herb can be used as medicine, and can be used for treating common cold, fever, laryngalgia, headache, conjunctival congestion, myalgia, skin rubella pruritus, measles without adequate eruption, etc., and also has effects on carbuncle, cellulitis, scabies, tinea, and dermatitis rhus.

Mu Li is first listed in Shen nong Ben Cao Jing (Shen nong's herbal), which is listed as the top grade in the book. Wherein, the oyster is regarded as having moderate taste and has the functions of treating weakness, relieving erysipelas, lowering blood pressure, nourishing yin and strengthening yang.

Yu xing Cao is pungent in flavor and cold in nature and enters lung meridian. It has effects of clearing away heat and toxic materials, relieving swelling, treating sore, inducing diuresis, removing dampness, clearing away heat, relieving dysentery, invigorating stomach, and resolving food stagnation, and can be used for treating lung abscess, pyocutaneous disease, hemorrhoid hematochezia, and heat accumulation of spleen and stomach due to excess heat, heat toxin, dampness, and disease heat. Modern pharmacological experiments show that the product has antibacterial, antiviral, immunity improving, and diuretic effects.

Licorice root: sweet and neutral. [ GUIJING ] Heart, lung, spleen and stomach meridians. [ EFFECT ] the medicine has effects of invigorating spleen and replenishing qi, clearing away heat and toxic material, eliminating phlegm and relieving cough, relieving spasm and pain, and harmonizing the drugs. For: weakness of spleen and stomach, lassitude and hypodynamia, palpitation and shortness of breath, cough with profuse sputum, spasm and pain of abdomen and limbs, carbuncle and sore, and relieving toxicity and strong nature of the medicine

Natural indigo, name of Chinese traditional medicine. Is prepared from leaf or stem of Acanthaceae plant herba Strychni, Polygonum tinctorium L of Polygonaceae, and Isatis tinctoria of Cruciferae by processing to obtain dry powder, mass or granule. Has the functions of clearing away heat and toxic material, cooling blood, eliminating spot, purging fire, arresting convulsion, etc. The nature and taste are salty and cold, and the medicine has the efficacies of clearing away heat and toxic material, cooling blood and removing ecchymoses, purging fire and arresting convulsion and the like. It is mainly used for treating epidemic febrile disease with excessive heat, macula, hematemesis, hemoptysis, pharyngalgia, aphtha, infantile convulsion, sore, swelling, erysipelas, snake and insect bite, etc.

Polygonatum sibiricum (scientific name: Polygonatum sibiricum), also known as: rhizoma Polygonati, herba Elsholtziae Pendulifoliae, rhizoma Gynurae Divaricatae, rhizoma Zingiberis recens, and radix Codonopsis Lanceolatae. Is a plant of Polygonatum with transverse rhizome, cylindrical shape and enlarged nodule. The impeller is raw and has no handle. The medicinal plant has the functions of invigorating spleen, moistening lung and promoting fluid production.

Myrrh, name of traditional Chinese medicine. Is dried resin of Commiphora myrrha Engl. or Commiphora molmol Engl. of Burseraceae; has the effects of removing blood stasis, relieving pain, eliminating swelling and promoting granulation. It is often used for treating thoracic obstruction, heart pain, epigastric pain, dysmenorrhea, amenorrhea, postpartum stasis, abdominal mass, rheumatic arthralgia, traumatic injury, carbuncle, swelling, sore and ulcer.

Dragon's blood, name of traditional Chinese medicine. Is prepared from resin exuded from fruit of daemonorops draco of Palmae by processing. Has effects of promoting blood circulation, relieving pain, removing blood stasis, stopping bleeding, promoting granulation, and healing sore. Can be used for treating traumatic injury, heart and abdomen blood stasis and pain, traumatic hemorrhage, and unhealed skin and external diseases.

Abalone shell, name of Chinese herbal medicine. The product is shell of Haliotis diversicolor (Haliotis diversicolor) or Haliotis diversicolor (pall.) pers. The main functional indications are as follows: pacify liver and subdue yang, remove heat and improve vision. It is indicated for wind-yang disturbance, headache, vertigo, convulsion, bone-steaming, fever, and cataract due to cyanosis.

According to the technical scheme, compared with the prior art, the traditional Chinese medicine composition has the effects of diminishing inflammation, promoting blood circulation to remove blood stasis, removing freckles, diminishing swelling and relieving pain, can effectively reduce the occurrence frequency of psoriasis diseases, achieves the purpose of treating the psoriasis diseases, is suitable for various types of psoriasis, has no side effect after treatment, is not easy to relapse, is simple and convenient to operate, and is low in price, and the selected traditional Chinese medicine raw materials are easy to obtain.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example 1: get

Example 2: get

Example 3: get

The preparation method comprises the following steps: pulverizing the above materials into 100 mesh fine powder, mixing, sterilizing according to conventional method, and making into capsule.

In order to show the treatment effect of the traditional Chinese medicine composition on psoriasis, the traditional Chinese medicine composition is used for carrying out clinical effect observation on 200 psoriasis patients, and the results show that: the effective rate is 95%, and the cure rate is 93%, and the specific steps are as follows:

200 patients with psoriasis vulgaris, symptoms: spots or plaques appear on the skin, thicker silvery white phosphorus scraps are arranged on the surface of the skin, the skin has irregular shape, some patterns or island-like appearances, some skin damages are small and have the appearance of a starry sky, the scale layer continuously drops off, a thin red film can be seen by slightly scraping the scales, small bleeding points can be seen by scraping the red film, and the whole body is itchy; after the medicine is taken for 1-2 months, the affected part does not itch any more, silvery white phosphorus scraps on the surface of the skin fall off, the skin is reddish, and the affected part can be healed after the medicine is taken for 1-2 months.

Typical cases are as follows:

the patient is covered with: for men, the male is 37 years old, 8 years old of illness is suffered, plaque erythema and scales exist on the body, the skin is seriously damaged after desquamation, the whole body is swollen, peculiar itch cannot be endured, neck, oxter and inguinal lymph node are swollen, constipation and anorexia are reduced for four months, the condition of the male cannot be controlled after 5 bottles of imported methotrexate and various therapies are injected, the disease condition is gradually aggravated, the work and the life cannot be normally carried out, the oral granules are taken for 40 days, the effect is remarkable, skin lesions are gradually healed, the itching is disappeared, the skin is normally recovered after the oral granules are continuously taken for 30 days, and the female is healed after the consolidation is taken for 10 days.

The patient has a certain von, female, 60 years old, suffers from the disease for 16 years, the chest and the back are surrounded by scales to form a group, the skin is dry, desquamation and pruritus, the western medicine is taken for the first time, the psoriasis recurs after stopping taking, the oral granules begin to drop after 30 days, the area of the skin injury is gradually reduced, after 40 days, the clinical symptoms are basically eliminated, and the patient is cured after 20 days of consolidation taking.

The embodiments in the present description are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other. The device disclosed by the embodiment corresponds to the method disclosed by the embodiment, so that the description is simple, and the relevant points can be referred to the method part for description.

The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. The oral granule for treating psoriasis is characterized in that the medicine is prepared by taking the following traditional Chinese medicines as raw materials in parts by weight:

2. the oral granule for treating psoriasis as claimed in claim 1, wherein the medicament is prepared from the following Chinese medicinal herbs (by weight portion):

3. the oral granule for treating psoriasis as claimed in claim 1, wherein the medicament is prepared from the following Chinese medicinal herbs (by weight portion):