CN1110168A

CN1110168A - Powder for curing wind-cold type of common cold and preparing method thereof

Info

Publication number: CN1110168A
Application number: CN 94110522
Authority: CN
Inventors: 邓庆林; 李玉真; 窦钦鸿
Original assignee: Linqing Traditional Chinese Pharmaceutical Factory
Current assignee: Linqing Traditional Chinese Pharmaceutical Factory
Priority date: 1994-04-07
Filing date: 1994-04-07
Publication date: 1995-10-18

Abstract

The present invention provides a powder preparation for curing wind-cold type of common cold and its preparation method. Its medicine composition includes (wt%) 5-10% of cinnamom twig, 5-10% of ledebouriella root, 3-10% of schizonepeta spike, 5-10% of white peony root, 3-10% of platycodon root, 1-5% of liquorice, 5-10% of dahurian angelica root, 5-10% of bupleurum root, 3-10% of notopterygium root, 5-10% of pueraria root, 3-10% of apricot kernel and 3-10% of fresh ginger. When preparing, the above-mentioned materials are passed through such processes of distillation, filtering and decocting so as to extract their effective components, and then the effective components are passed through such processes of filtering, concentrating, granulating, drying and moistening to obtain the invented powder preparation. It is mainly used for curing aversion to cold, fever, headache, general aching, cough, watery nasal discharge, etc. due to pathogenic wind-cold, and its cure rate is 74.66%.

Description

Powder for curing wind-cold type of common cold and preparing method thereof

The present invention relates to a kind of electuary and manufacture method of utilizing the Chinese herbal treatment affection of exogenous wind-cold.

Flu is a kind of of a kind of commonly encountered diseases and frequently-occurring disease, in Chinese medicine, belong to exterior syndrome, the treatment diaphoretic therapys of using more, different diaphoretic recipess according to the exterior syndrome cold and heat are divided into relieving the exterior syndrome with drugs of pungent in flavor and warm in nature and relieving the exterior syndrome with drugs of pungent in flavor and cool in nature two big classes more, the Chinese patent medicine that is used for the treatment of flu at present belongs to the agent of relieving the exterior syndrome with drugs of pungent in flavor and cool in nature or refreshing and detoxicating more, and all there is morbidity in the anemofrigid cold four seasons, and it is higher with the winter-spring season sickness rate, the drug effect fruit commonly used that is used for the treatment of this disease is assisted contac etc. as quick-acting cold glue preferably, its cure rate only is that 51.47% total effective rate is 85.29%, and its cure rate and effective percentage are not very good.And that contac uses at the initial stage of a disease is the most effective, takes when promptly beating first sneeze.Do not produce or report was led and also had with the Chinese patent medicine that electuary is treated affection of exogenous wind-cold.

The purpose of this invention is to provide a kind of powder for curing wind-cold type of common cold and manufacture method,

The weight percentage of each component of powder for curing wind-cold type of common cold of the present invention is

Ramulus Cinnamomi 5-10 Radix Saposhnikoviae 5-10 Herba Schizonepetae 3-10 Radix Paeoniae Alba 5-10

Radix Platycodonis 3-10 Radix Glycyrrhizae 1-5 Radix Angelicae Dahuricae 5-10 Radix Bupleuri 5-10

Rhizoma Et Radix Notopterygii 3-10 Radix Puerariae 5-10 Semen Armeniacae Amarum 3-10 Rhizoma Zingiberis Recens 3-10

Its manufacture method is:

1, with Ramulus Cinnamomi, Herba Schizonepetae, Radix Bupleuri, Rhizoma Et Radix Notopterygii, extract its volatile oil with the way of distillation, the medicinal residues after distillation device are in addition collected for back operation use.

2, the Radix Angelicae Dahuricae is made solvent with 60% ethanol and is extracted with percolation.

3, medicinal residues and the solution behind Radix Saposhnikoviae, the Radix Paeoniae Alba, Radix Puerariae, Radix Platycodonis, Semen Armeniacae Amarum, Radix Glycyrrhizae, Rhizoma Zingiberis Recens and Ramulus Cinnamomi, Herba Schizonepetae, Radix Bupleuri, the Rhizoma Et Radix Notopterygii extraction volatile oil extracts with decocting method in the lump, decocted 2-3 hour for the first time, decocted 1-2 hour for the second time, merge the decoction liquor filter and remove residue, with static 24 hours of filtrate, get supernatant and add Radix Angelicae Dahuricae extracting solution and be condensed into the clear paste that proportion is 1.35-1.38.

4,1 part of qinghuo reagent is with 1 part in 3 parts of dextrin of sucrose, and an amount of ethanol makes granule, again drying machine drying.

5, with the volatile oil mixing moistening of dried granule and Ramulus Cinnamomi, Herba Schizonepetae, Radix Bupleuri, Rhizoma Et Radix Notopterygii 12-24 hour, pack out finished product.

The pharmacology analysis of powder for curing wind-cold type of common cold of the present invention: anemofrigid cold is an affection by exopathogenic cold-wind from the angle of the traditional Chinese medical science, the defensive QI being obstructed good and evil are handed over and are striven, it is unfavorable that villous themeda is defended operation, and lung qi a surname falls not normal, as above-mentioned all diseases, treatment is when the diaphoresis expelling cold and relieving exterior syndrome, should form with the Guizhi Jia Gegen Tang plus-minus, wherein Ramulus Cinnamomi has the diaphoresis expelling pathogenic factors from muscles, the effect in warming the meridian Yiyang, but perspiration relaxes, and Rhizoma Et Radix Notopterygii is used to separate the wind-cold damp pathogen that is dispersed in table and removes general pain.Radix Angelicae Dahuricae expelling cold and relieving exterior syndrome and kind end headache.The effect of Fang-feng bupleurum root, Herba Schizonepetae is gently to open clearly to loose to dredge evil expelling pathogenic factors from the exterior, and warm and not dry, diffusing and not high.The effect of Rhizoma Zingiberis Recens is the expelling cold and relieving exterior syndrome warming the lung to relieve cough.The effect of Radix Puerariae be relieving muscles diaphoresis bring down a fever promote the production of body fluid, the kind stiff nape and back of controlling, the Radix Paeoniae Alba yin fluid astringing that nourishes blood is joined Ramulus Cinnamomi blending villous themeda and is defended, expelling pathogenic factors from muscles is delivered with the anti-altogether hot medicine warm-dryness syndrome impairment of YIN of loosing of Radix Puerariae.The effect of Radix Platycodonis is out lung qi dispersing gas expelling phlegm for arresting cough, and Semen Armeniacae Amarum has the therapeutic method to keep the adverse QI flowing downwards to relieving asthma, and Radix Glycyrrhizae has transfers during medicine closes the function of expelling phlegm for arresting cough.

Embodiment:

1, get Ramulus Cinnamomi 100g, Herba Schizonepetae 100g, Radix Bupleuri 100g, Rhizoma Et Radix Notopterygii 70g, soak then and extract its volatile oil respectively with the way of distillation, volatile oil, solution and medicinal residues are collected for future use respectively.

2, get Radix Angelicae Dahuricae 100g, suitably fragmentation adds 60% ethanol and soaks into to insert in 5-12 hour in the percolation filter and put 24 hours, carries out diafiltration then, and leachate collection is returned ethanol, and remainder is an extracting solution.

3, get Radix Saposhnikoviae 100g, Radix Paeoniae Alba 100g, Radix Puerariae 120g, Radix Platycodonis 70g, Semen Armeniacae Amarum 70g, Radix Glycyrrhizae 15g, Rhizoma Zingiberis Recens 70g, with Radix Angelicae Dahuricae medicinal residues and the solution after Ramulus Cinnamomi, Herba Schizonepetae, Radix Bupleuri and the diafiltration of extracting volatile oil, decoct with water in the lump, decocted 2 hours for the first time, decocted 1.5 hours for the second time, close preceding twice decoction liquor and filter static 12 hours of filtrate, the extracting solution of getting the supernatant and the Radix Angelicae Dahuricae merges, and is condensed into the clear paste that proportion is 1.35-1.38.

4,1 part of qinghuo reagent is with 3 parts of sucrose, and 1 part in dextrin and an amount of ethanol mix, and make particle drying by granulation machine.

5, with the volatile oil mixing moistening of dried granule and Ramulus Cinnamomi, Herba Schizonepetae, Radix Bupleuri, Rhizoma Et Radix Notopterygii 12-24 hour, be finished product.

Powder for curing wind-cold type of common cold of the present invention, function with cure mainly: the cold expelling that induces sweat, relieving fever and suppressing cough is used for anemofrigid cold, fever with aversion to cold, headache stiffness of the nape systemic pain, nasal obstruction watery nasal discharge, diseases such as cough, tongue fur are thin in vain, floating pulse.

Powder for curing wind-cold type of common cold of the present invention is compared with existing treatment anemofrigid cold Chinese patent drug has cure rate and total effective rate height, and medication is convenient not to be had to pay to do and the advantage such as use, and is the substitute products of the various cold medicines of existing treatment, has good market prospects.

Claims

1, powder for curing wind-cold type of common cold and manufacture method, it be by the Chinese herbal medicine of following component by weight percentage example combine Ramulus Cinnamomi 5-10, Radix Saposhnikoviae 5-10, Herba Schizonepetae 3-10, Radix Paeoniae Alba 5-10, Radix Platycodonis 3-10, Radix Glycyrrhizae 1-5, Radix Angelicae Dahuricae 5-10, Radix Bupleuri 5-10, Rhizoma Et Radix Notopterygii 3-10, Radix Puerariae 5-10, Semen Armeniacae Amarum 3-10, Rhizoma Zingiberis Recens 3-10.

2, according to described powder for curing wind-cold type of common cold of claim 1 and manufacture method, it is characterized in that Ramulus Cinnamomi, Herba Schizonepetae, Radix Bupleuri, Rhizoma Et Radix Notopterygii extract its volatile oil with the way of distillation respectively, the medicinal residues solution after distillation device is in addition collected for back operation use.

3,, it is characterized in that the Radix Angelicae Dahuricae makees solvent with 60% ethanol and extract with percolation according to described powder for curing wind-cold type of common cold of claim 1 and manufacture method.

4, according to described powder for curing wind-cold type of common cold of claim 1 and manufacture method, it is characterized in that medicinal residues and solution that Radix Saposhnikoviae, the Radix Paeoniae Alba, Radix Puerariae, Radix Platycodonis, Semen Armeniacae Amarum, Radix Glycyrrhizae, Rhizoma Zingiberis Recens and Ramulus Cinnamomi, Herba Schizonepetae, Radix Bupleuri, Rhizoma Et Radix Notopterygii are extracted behind the volatile oil extract with decocting method, decocted 2-3 hour for the first time, decocted 1-2 hour for the second time.

5, according to described powder for curing wind-cold type of common cold of claim 1 and manufacture method, it is characterized in that secondary decoction liquor merging first time is filtered, static 24 hours of filtrate is got the extracting solution that supernatant adds the Radix Angelicae Dahuricae, is condensed into the clear paste that proportion is 1.35-1.38.

6, according to described powder for curing wind-cold type of common cold of claim 1 and manufacture method, it is characterized in that getting 1 part of clear paste after concentrating, 3 parts of sucrose, 1 part in dextrin and adequate amount of ethanol are made granule, add the volatile oil mixing moistening 24 hours of Ramulus Cinnamomi, Herba Schizonepetae, Radix Bupleuri, Rhizoma Et Radix Notopterygii after drying.