CN110996998A - 表达rsv g的重组嵌合牛/人副流感病毒3及其用途 - Google Patents

表达rsv g的重组嵌合牛/人副流感病毒3及其用途 Download PDF

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CN110996998A
CN110996998A CN201880048358.8A CN201880048358A CN110996998A CN 110996998 A CN110996998 A CN 110996998A CN 201880048358 A CN201880048358 A CN 201880048358A CN 110996998 A CN110996998 A CN 110996998A
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rsv
hpiv3
amino acid
acid sequence
protein
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CN201880048358.8A
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P·L·柯林斯
U·J·布赫霍尔茨
梁波
S·穆尼尔
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US Department of Health and Human Services
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
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    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
    • C12N2760/18641—Use of virus, viral particle or viral elements as a vector
    • C12N2760/18643—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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CN201880048358.8A 2017-05-29 2018-05-29 表达rsv g的重组嵌合牛/人副流感病毒3及其用途 Pending CN110996998A (zh)

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US201762512111P 2017-05-29 2017-05-29
US62/512,111 2017-05-29
PCT/US2018/034848 WO2018222573A1 (en) 2017-05-29 2018-05-29 Recombinant chimeric bovine/human parainfluenza virus 3 expressing rsv g and its use

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EP (1) EP3630173A1 (enExample)
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CA (1) CA3064267A1 (enExample)
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Publication number Priority date Publication date Assignee Title
CA3216466A1 (en) * 2021-04-27 2022-11-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Recombinant chimeric bovine/human parainfluenza virus 3 expressing sars-cov-2 spike protein and its use
CN118302191A (zh) 2021-11-30 2024-07-05 圣诺菲·帕斯图尔公司 基于病毒载体的人偏肺病毒疫苗
CN115925822B (zh) * 2022-09-01 2024-01-09 广州源博医药科技有限公司 一种重组蛋白及其在制备呼吸道合胞病毒疫苗中的应用

Citations (5)

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Publication number Priority date Publication date Assignee Title
CN1306575A (zh) * 1997-05-23 2001-08-01 美国政府健康及人类服务部 从克隆的核苷酸序列制备减毒副流感病毒疫苗的方法
WO2003072725A2 (en) * 2002-02-21 2003-09-04 Mount Sinai School Of Medicine Recombinant negative strand virus rna expression systems and vaccines
US6764685B1 (en) * 2000-03-21 2004-07-20 Medimmune Vaccines, Inc. Recombinant parainfluenza virus expression systems and vaccines
CN102766605A (zh) * 1999-12-10 2012-11-07 由卫生与公众服务部代表的美利坚合众国政府 重组副流感病毒(piv)作为载体提供保护对抗piv及其他人类病原体引起的感染和疾病的用途
WO2016118642A1 (en) * 2015-01-20 2016-07-28 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Recombinant human/bovine parainfluenza virus 3 (b/hpiv3) expressing a chimeric rsv/bpiv3 f protein and uses thereof

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AU605476B2 (en) * 1986-01-14 1991-01-17 University Of North Carolina, The Vaccines for human respiratory virus
US7201907B1 (en) 1997-05-23 2007-04-10 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Attenuated human-bovine chimeric parainfluenza virus(PIV) vaccines
US7632508B2 (en) 1997-05-23 2009-12-15 The United States Of America Attenuated human-bovine chimeric parainfluenza virus (PIV) vaccines
US7250171B1 (en) 1997-05-23 2007-07-31 United States Of America As Represented By The Dept. Of Health & Human Services Construction and use of recombinant parainfluenza viruses expressing a chimeric glycoprotein
US7192593B2 (en) 1997-05-23 2007-03-20 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Use of recombinant parainfluenza viruses (PIVs) as vectors to protect against infection and disease caused by PIV and other human pathogens
US20030082209A1 (en) 2000-07-05 2003-05-01 Skiadopoulos Mario H. Attenuated human-bovine chimeric parainfluenza virus (PIV) vaccines
US7208161B1 (en) 1997-05-23 2007-04-24 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Production of attenuated parainfluenza virus vaccines from cloned nucleotide sequences
CA2477235A1 (en) 2002-02-21 2003-09-04 Medimmune Vaccines, Inc. Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from metapneumovirus
CA2523657A1 (en) 2003-04-25 2005-03-31 Medimmune Vaccines, Inc. Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from metapneumovirus
US9216212B2 (en) * 2005-08-05 2015-12-22 University Of Massachusetts Virus-like particles as vaccines for paramyxovirus
EP2069485A4 (en) 2007-07-13 2011-05-25 Medimmune Llc PREPARATION OF NEGATIVE STRAND RNA VIRUSES BY ELECTROPORATION
BR112018011674A2 (pt) * 2015-12-11 2018-12-04 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services cepas do vírus sincicial respiratório recombinante com mutações na orf de m2-2 fornecendo uma faixa de fenótipos de atenuação

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CN1306575A (zh) * 1997-05-23 2001-08-01 美国政府健康及人类服务部 从克隆的核苷酸序列制备减毒副流感病毒疫苗的方法
CN102766605A (zh) * 1999-12-10 2012-11-07 由卫生与公众服务部代表的美利坚合众国政府 重组副流感病毒(piv)作为载体提供保护对抗piv及其他人类病原体引起的感染和疾病的用途
US6764685B1 (en) * 2000-03-21 2004-07-20 Medimmune Vaccines, Inc. Recombinant parainfluenza virus expression systems and vaccines
WO2003072725A2 (en) * 2002-02-21 2003-09-04 Mount Sinai School Of Medicine Recombinant negative strand virus rna expression systems and vaccines
WO2016118642A1 (en) * 2015-01-20 2016-07-28 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Recombinant human/bovine parainfluenza virus 3 (b/hpiv3) expressing a chimeric rsv/bpiv3 f protein and uses thereof

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ALEXANDER C. SCHMIDT ET AL.: "Bovine Parainfluenza Virus Type 3 (BPIV3) Fusion and Hemagglutinin-Neuraminidase Glycoproteins Make an Important Contribution to the Restricted Replication of BPIV3 in Primates", 《JOURNAL OF VIROLOGY》 *
BO LIANG ET AL.: "Chimeric Bovine/Human Parainfluenza Virus Type 3 Expressing Respiratory Syncytial Virus (RSV) F Glycoprotein: Effect of Insert Position on Expression, Replication, Immunogenicity, Stability, and Protection against RSV Infection", 《JOURNAL OF VIROLOGY》 *
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JP2020522249A (ja) 2020-07-30
US20220226458A1 (en) 2022-07-21
JP2023093566A (ja) 2023-07-04
JP7314059B2 (ja) 2023-07-25
WO2018222573A1 (en) 2018-12-06
EP3630173A1 (en) 2020-04-08
US11273214B2 (en) 2022-03-15
CA3064267A1 (en) 2018-12-06
US11975063B2 (en) 2024-05-07
US20210145958A1 (en) 2021-05-20

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