CN110945593A - 用于预测生物反应器中的过程的产出和对生物反应器中的过程建模的方法 - Google Patents

用于预测生物反应器中的过程的产出和对生物反应器中的过程建模的方法 Download PDF

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Publication number
CN110945593A
CN110945593A CN201880052944.XA CN201880052944A CN110945593A CN 110945593 A CN110945593 A CN 110945593A CN 201880052944 A CN201880052944 A CN 201880052944A CN 110945593 A CN110945593 A CN 110945593A
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current
model
bioreactor
run
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K.K.斯瓦米纳森
S.达萨拉萨
S.乔治
V.B.雅穆
A.S.乔汉
N.孔杜卢
N.博达帕蒂
A.巴蒂亚
M.莫汉蒂
H.阿隆
A.卡斯坦
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Global Life Sciences Solutions USA LLC
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GE Healthcare Bio Sciences Corp
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    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F30/00—Computer-aided design [CAD]
    • G06F30/20—Design optimisation, verification or simulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B13/00—Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion
    • G05B13/02—Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric
    • G05B13/04—Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric involving the use of models or simulators
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B17/00—Systems involving the use of models or simulators of said systems
    • G05B17/02—Systems involving the use of models or simulators of said systems electric

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  • General Engineering & Computer Science (AREA)
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  • Automation & Control Theory (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Sustainable Development (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Software Systems (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Testing And Monitoring For Control Systems (AREA)
CN201880052944.XA 2017-06-16 2018-06-18 用于预测生物反应器中的过程的产出和对生物反应器中的过程建模的方法 Pending CN110945593A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN201741021125 2017-06-16
IN201741021125 2017-06-16
PCT/IN2018/050398 WO2018229802A1 (en) 2017-06-16 2018-06-18 Method for predicting outcome of and modelling of a process in a bioreactor

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CN110945593A true CN110945593A (zh) 2020-03-31

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US (2) US12182482B2 (https=)
EP (1) EP3639171A4 (https=)
JP (1) JP7852898B2 (https=)
CN (1) CN110945593A (https=)
WO (1) WO2018229802A1 (https=)

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US11567488B2 (en) 2021-05-27 2023-01-31 Lynceus, Sas Machine learning-based quality control of a culture for bioproduction
EP4116403A1 (en) * 2021-07-07 2023-01-11 Sartorius Stedim Data Analytics AB Monitoring, simulation and control of bioprocesses
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CN113189973A (zh) * 2020-12-09 2021-07-30 淮阴工学院 基于函数观测器的二级化学反应器执行器故障检测方法

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EP3639171A1 (en) 2020-04-22
US20250068794A1 (en) 2025-02-27
WO2018229802A1 (en) 2018-12-20
JP7852898B2 (ja) 2026-04-28
JP2020523030A (ja) 2020-08-06
EP3639171A4 (en) 2021-07-28
US12182482B2 (en) 2024-12-31
US20200202051A1 (en) 2020-06-25

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