JP7852898B2 - バイオリアクタにおいてのプロセスのアウトカムを予測するための、および、そのプロセスのモデリングのための方法 - Google Patents

バイオリアクタにおいてのプロセスのアウトカムを予測するための、および、そのプロセスのモデリングのための方法

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Publication number
JP7852898B2
JP7852898B2 JP2019569403A JP2019569403A JP7852898B2 JP 7852898 B2 JP7852898 B2 JP 7852898B2 JP 2019569403 A JP2019569403 A JP 2019569403A JP 2019569403 A JP2019569403 A JP 2019569403A JP 7852898 B2 JP7852898 B2 JP 7852898B2
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model
current
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predicting
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JP2020523030A5 (https=
JP2020523030A (ja
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クリシュナ・クマール・スワミナサン
スリダール・ダサラサ
シッタル・ジョージ
ヴィナイ・バスカー・ジャム
アロク・シン・チャウハン
ナガラジュ・コンドゥル
ニーリマ・ボダパティ
アンキタ・バティア
ミティレシュ・モハンティ
ハルシャ・アーロン
アンドレアス・カスタン
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Cytiva Sweden AB
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Amersham Bioscience AB
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F30/00—Computer-aided design [CAD]
    • G06F30/20—Design optimisation, verification or simulation
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B13/00—Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion
    • G05B13/02—Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric
    • G05B13/04—Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric involving the use of models or simulators
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B17/00—Systems involving the use of models or simulators of said systems
    • G05B17/02—Systems involving the use of models or simulators of said systems electric

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  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
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  • Evolutionary Computation (AREA)
  • Computer Hardware Design (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Automation & Control Theory (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Geometry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Sustainable Development (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Software Systems (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Testing And Monitoring For Control Systems (AREA)
JP2019569403A 2017-06-16 2018-06-18 バイオリアクタにおいてのプロセスのアウトカムを予測するための、および、そのプロセスのモデリングのための方法 Active JP7852898B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN201741021125 2017-06-16
IN201741021125 2017-06-16
PCT/IN2018/050398 WO2018229802A1 (en) 2017-06-16 2018-06-18 Method for predicting outcome of and modelling of a process in a bioreactor

Publications (3)

Publication Number Publication Date
JP2020523030A JP2020523030A (ja) 2020-08-06
JP2020523030A5 JP2020523030A5 (https=) 2021-07-26
JP7852898B2 true JP7852898B2 (ja) 2026-04-28

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Country Status (5)

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US (2) US12182482B2 (https=)
EP (1) EP3639171A4 (https=)
JP (1) JP7852898B2 (https=)
CN (1) CN110945593A (https=)
WO (1) WO2018229802A1 (https=)

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TWI781408B (zh) * 2019-11-27 2022-10-21 靜宜大學 利用高光譜資料分析技術之人工智慧的細胞檢測方法及其系統
EP3839036B1 (en) * 2019-12-19 2023-04-19 DSM IP Assets B.V. A digital twin for monitoring and controlling an industrial bioprocess
WO2021234732A1 (en) * 2020-05-19 2021-11-25 Tata Consultancy Services Limited System and method for development and deployment of self-organizing cyber-physical systems for manufacturing industries
GB202015861D0 (en) * 2020-10-07 2020-11-18 National Institute For Bioprocesisng Res And Training Method and system for predicting the performance for biopharmaceutical manufacturing processes
CN113189973B (zh) * 2020-12-09 2023-03-21 淮阴工学院 基于函数观测器的二级化学反应器执行器故障检测方法
US11567488B2 (en) 2021-05-27 2023-01-31 Lynceus, Sas Machine learning-based quality control of a culture for bioproduction
EP4116403A1 (en) * 2021-07-07 2023-01-11 Sartorius Stedim Data Analytics AB Monitoring, simulation and control of bioprocesses
JP2025503486A (ja) * 2021-12-21 2025-02-04 パウ ジェネティック ソリューションズ インコーポレイテッド 培養プロセスにおける培養条件を最適化するための方法およびシステム
WO2024064890A1 (en) * 2022-09-23 2024-03-28 Metalytics, Inc. Using the concepts of metabolic flux rate calculations and limited data to direct cell culture. media optimization and enable the creation of digital twin software platforms
US20240112750A1 (en) * 2022-10-04 2024-04-04 BioCurie Inc. Data-driven process development and manufacturing of biopharmaceuticals

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Also Published As

Publication number Publication date
EP3639171A1 (en) 2020-04-22
US20250068794A1 (en) 2025-02-27
WO2018229802A1 (en) 2018-12-20
CN110945593A (zh) 2020-03-31
JP2020523030A (ja) 2020-08-06
EP3639171A4 (en) 2021-07-28
US12182482B2 (en) 2024-12-31
US20200202051A1 (en) 2020-06-25

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