CN110935014A - Special natural herbal oral skin mucosa disinfection spray for children - Google Patents

Abstract

The invention relates to a special natural herbal oral skin mucosa disinfection spray for children, which is prepared by extracting and compounding dandelion extract, plant stem cell essence, mint stem cells, compound lysozyme, sweet orange peel oil, probiotics, honeysuckle extract, chitosan derivatives, sesamin, sow thistle flower extract, natural citric acid and the like through a special process, and is mainly used for disinfection and nursing of children oral mucosa. The invention provides a novel natural herbal medicine, which is extracted from pure natural herbs, has the characteristics of high-efficiency sterilization and disinfection, safety, no toxicity, no stimulation, greenness and environmental protection. The invention can effectively protect the oral health of children, achieves the effects of removing oral peculiar smell, preventing decayed teeth, firming teeth, nourishing gingiva and healthy periodontal, and is suitable for daily oral care of children.

Description

Special natural herbal oral skin mucosa disinfection spray for children

The invention relates to a special natural herbal oral skin mucosa disinfection spray for children, which is prepared by extracting and compounding dandelion extract, plant stem cell essence, mint stem cells, compound lysozyme, sweet orange peel oil, probiotics, honeysuckle extract, chitosan derivatives, sesamin, sow thistle flower extract, natural citric acid and the like through a special process, and is mainly used for disinfection and nursing of children oral mucosa. Currently, there is a lack in the market of effective, safe, children's dedicated oral cleaning products without harmful chemical additives. The invention aims to provide the children special oral cavity disinfection spray extracted from pure natural herbs and without any chemical component, particularly, natural disinfection components such as compound lysozyme and probiotics are added, and natural citric acid is used as an acid-base regulator to regulate the pH value of the solution to weak acidity suitable for skin, so that the children special oral cavity disinfection spray has the characteristics of high-efficiency disinfection, safety, no toxicity, no stimulation, greenness and environmental protection. The invention can effectively protect the oral health of children, achieves the effects of removing oral peculiar smell, preventing decayed teeth, firming teeth, nourishing gingiva and healthy periodontal, and is suitable for daily oral care of children.

Background artthe oral cavity is an important component of the digestive and respiratory systems of the human body, and oral diseases are on an increasing trend along with the aggravation of problems such as air pollution and environmental deterioration. Various bacteria and viruses hardly enter the product in life. When children are in a stage of rapid body development, the children eat more times and the types of foods are complex, most of the foods are foods with high sugar content and easy to ferment to produce acid, such as cakes, candies, chocolates and the like, and the foods are easy to adhere to teeth; the children have poor self-oral health care capability and bad oral hygiene, so that food and soft dirt are easy to be retained on the tooth surface; the form of deciduous teeth is favorable for food residue and bacteria reproduction. All of the above factors are likely to cause dental caries, pulposis and periapical disease in children. In daily life, people are accustomed to cleaning teeth and oral cavity with toothpaste, but it is very important for children who do not brush teeth or who reject brushing teeth to maintain oral health through an effective oral care method. At present, the children oral care method mainly achieves the effects of cleaning and eliminating oral odor by gargling the oral cavity with mouth wash, oral care solution and the like, and also has the effects of removing dental plaque and killing bacteria in the oral cavity with the oral care solution. Most mouthwashes have anticaries effect and contain fluoride, which damages enamel on children's teeth surface, resulting in incomplete enamel mineralization and finally dental fluorosis. In addition, children have an unsound swallowing function, and may swallow more fluorine-containing mouth wash to cause acute poisoning. It is necessary to research a new oral care method for children and develop a new oral care solution. Aiming at the problems, the invention particularly adds natural sterilization and disinfection components such as compound lysozyme, probiotics and the like, utilizes natural citric acid as an acid-base regulator to regulate the pH value of the solution to weak acidity suitable for skin, and has the characteristics of high-efficiency sterilization and disinfection, safety, no toxicity, no stimulation, greenness and environmental protection.

The key point of the invention is that a plurality of natural herbal essences are used, and the synergistic effect of plant stem cells, compound lysozyme and probiotics is matched, so that the effect of each effective component is strongest, the delicate skin of the children cannot be damaged, and the oral skin and mucous membrane disinfection spray special for the children is prepared by final compatibility.

The formula selected by the invention is as follows (components and weight percentage): 1.0-1.5 of dandelion extract; 0.1-0.5 of plant stem cell essence; sweet orange peel oil 0.7-1.0; mint stem cells 0.1-0.5; 0.1-0.5 of chitosan derivative; 0.1-0.5 of sesamin; 0.1-0.5 of sow thistle flower extract; 1.0-1.5 of probiotics; 1.0-1.5 of honeysuckle extract; 0.1-0.5 of compound lysozyme; the pH was adjusted to 6.8 with natural citric acid and purified water was added to 100.

The dandelion plant contains various health nutritional components such as taraxol, taraxacin, choline, organic acid, inulin, etc. Sweet in nature and taste, slightly bitter and cold. It enters liver and stomach meridians. Has diuretic, laxative, jaundice treating, and gallbladder promoting effects. Has strong bactericidal effect on staphylococcus aureus drug-resistant strains and hemolytic streptococcus. It also has antibacterial effect on Diplococcus pneumoniae, meningococcus, diphtheria bacillus, Pseudomonas aeruginosa, Shigella dysenteriae, typhoid bacillus, etc., and on Catalpa coccus. The alcohol extract can kill leptospira and inhibit some fungi. Has good killing effect on helicobacter pylori.

The growth factors and other signal molecules released by the plant stem cell essence stimulate the natural self-repair and regeneration functions of the skin. We used extracts of stem cells rather than directly stem cells, as they were the purest, most stable, and ensured that the components were in a high quality state. These extracts can greatly increase the rate of regeneration of skin cells by increasing the number, lifespan and function of skin's own stem cells.

Sweet orange peel oil is one of the few essential oils which have been shown to have a sedative effect, has a sweet orange flavor, is used as a fragrance, can repel stress and stress, and improves insomnia caused by anxiety. It can be used for the care of dry and aged skin in view of the proliferation and antioxidant effects of hyaluronic acid.

The probiotics is a compound biological preparation refined by fermenting, purifying and drying beneficial microorganisms in animal intestinal tracts, and is an ideal green additive for replacing antibiotics due to no toxic or side effect, no drug residue and no drug resistance in the using process. Can promote growth and development of children, improve disease resistance, stimulate immune system, and enhance specific cellular immune response. Producing beneficial metabolites. The probiotics generate organic acid such as lactic acid in the digestive tract, and the acidification effect of the probiotics can improve the utilization rate of daily ration nutrients, promote the growth of children and prevent diarrhea; producing carbohydrate decomposing enzymes such as amylase, protease, and xylanase, eliminating anti-nutritional factors, and promoting digestion and absorption; synthesize vitamins and chelate mineral elements, and provide essential nutrition for children.

Honeysuckle is known as a good medicine for clearing heat and removing toxicity from the old, has sweet and cold nature and aromatic qi, clears heat without hurting the stomach, has the effect of eliminating pathogenic factors by penetrating the aromatic qi, can disperse wind and heat, and also can clear and remove blood toxin, and has obvious effects on various heat diseases, such as fever, eruption, macula, heat toxin sores and carbuncles, sore throat and other symptoms.

The complex lysozyme can solubilize bacteria or yeast and fungal cell walls, resulting in microbial death. The non-enzymatic solubilization of the lysozyme product is one of the main factors for killing bacteria. The lysozyme can still maintain the bactericidal action after being heated and inactivated, which indicates the existence of non-enzymatic bactericidal action. The lysozyme can cooperate with various factors to broaden the bactericidal spectrum and enhance the bactericidal efficacy.

One of the main functions of the chitosan derivative in changing the permeability of cell membranes and cell walls of bacteria is to protect substances in cells from leaking outside the cells, influence of chitosan on the cell wall functions of escherichia coli and staphylococcus aureus, cell aggregation, unclear cell walls, more obvious change on the cell walls of staphylococcus aureus, and the phenomenon of cell wall fuzzy and plasmolysis, which shows that the chitosan has irreversible damage on the cell walls of the bacteria. Under acidic conditions, chitosan is adsorbed on cell walls as molecules, so that negative charges on the cell walls and cell membranes are unevenly distributed, cell wall synthesis is interfered, and bacteria are cracked and die.

Sesamum indicum L.of Brassicaceae can promote qi circulation, dispel phlegm, and relieve asthma. Treating phlegm retention, dyspnea and cough, edema and ascites. The sesamin has effects of relieving, and promoting urination. It can also lower lung qi and treat chronic cough and frequent micturition. The tender stem and leaf contains multiple vitamins and minerals.

Mint stem cell efficacy and action 1, refreshing, sterilizing and deodorizing: the mint tea can refresh the whole body when drinking a cup of mint tea in spring and summer and sleepy, and can effectively eliminate the peculiar smell of the oral cavity and effectively kill the bacteria in the oral cavity when gargling with the mint tea. 2. And (3) digestion promotion: the mint can promote digestion, reduce intestinal flatulence and eliminate the discomfort of nausea, heartburn and the like caused by overeating or dyspepsia.

The extract of the sow thistle flowers has the effects of clearing away heat and toxic materials, sterilizing and diminishing inflammation. The sow thistle contains taraxasterol, choline and other components, has a strong bactericidal effect on staphylococcus aureus drug-resistant strains and hemolytic streptococcus, and also has a certain killing effect on pneumococcus, meningococcus, diphtheria bacillus, pseudomonas aeruginosa, dysentery bacillus and the like, so the sow thistle has a certain curative effect on icterohepatitis, sphagitis, bacillary dysentery, cold fever, chronic tracheitis, tonsillitis and the like.

The natural citric acid is extracted from fruits such as lemon, orange, pineapple and the like, belongs to one of fruit acids, and mainly has the effect of accelerating cutin renewal. It is often used in lotion, cream, shampoo, whitening product, anti-aging product, and acne product. The pH regulator used as skin refreshing liquid instead of chemical strong acid can play a good role in cutin renewal, and is helpful for stripping melanin in skin, shrinking pores, dissolving blackheads and the like.

The preparation method of the product of the invention comprises the following steps:

(1) preparing an oil phase component: respectively preparing herba Taraxaci extract, sweet orange peel oil, chitosan derivative, sesamin, herba Sonchi Oleracei extract, and flos Lonicerae extract at a certain proportion, and mixing;

(2) preparing an aqueous phase component: adding herba Menthae and plant stem cell essence into marigold essence water at a certain proportion, dissolving and stirring;

(3) heating the water phase component to 40 ℃, slowly adding the oil phase component, and emulsifying uniformly;

(4) cooling the components to 25 ℃, slowly adding the probiotics and the compound lysozyme, and uniformly stirring;

(5) using natural citric acid as an acid-base regulator, regulating the pH value of the solution to 6.0, and purifying water to 100;

(6) randomly performing spot inspection, subpackaging into spray bottles after the inspection is qualified, labeling and sealing.

The invention has the following advantages:

(1) the compound lysozyme, the probiotics and the natural plant essence have synergistic effect, so that the effect of each effective component is strongest, and the delicate oral skin of the children cannot be damaged;

(2) the antibacterial and disinfection effect is obvious, and the bactericidal and bacteriostatic agent has the functions of killing and inhibiting bacteria, fungi and viruses;

(3) effectively eliminating peculiar smell in oral cavity, preventing dental caries, firming teeth, and achieving the effects of nourishing gingiva and health periodontal;

(4) the paint is safe, non-toxic, non-irritant, non-corrosive, non-destructive to skin and non-polluting to environment;

(5) the use concentration is low, and the stability is good;

(6) simple process and low cost.

The present invention will be described in further detail with reference to the following examples:

the configuration was carried out according to the data (in% by weight) listed in the following table and the procedure described therein:

the formula I is as follows:

1.0-1.5 of dandelion extract; 0.1-0.5 of plant stem cell essence; sweet orange peel oil 0.7-1.0; mint stem cells 0.1-0.5; 0.1-0.5 of chitosan derivative; 0.1-0.5 of sesamin; 0.1-0.5 of sow thistle flower extract; 1.0-1.5 of probiotics; 1.0-1.5 of honeysuckle extract; 0.1-0.5 of compound lysozyme; the pH was adjusted to 6.8 with natural citric acid and purified water was added to 100.

And a second formula:

1.2-1.5 of dandelion extract; 0.2-0.5 of plant stem cell essence; sweet orange peel oil 0.8-1.0; mint stem cells 0.2-0.5; 0.3-0.5 of chitosan derivative; 0.2-0.5 of sesamin; 0.3-0.5 of sow thistle flower extract; 1.2-1.5 of probiotics; 1.2-1.5 of honeysuckle extract; 0.2-0.5 of compound lysozyme; the pH was adjusted to 6.8 with natural citric acid and purified water was added to 100.

And the formula III:

1.0-1.4 of dandelion extract; 0.1-0.3 of plant stem cell essence; sweet orange peel oil 0.7-0.8; mint stem cells 0.1-0.4; 0.1-0.4 of chitosan derivative; 0.1-0.4 of sesamin; 0.1-0.3 of sow thistle flower extract; 1.0-1.3 of probiotics; 1.0-1.2 of honeysuckle extract; 0.1-0.3 of compound lysozyme; the pH was adjusted to 6.8 with natural citric acid and purified water was added to 100.

The applicant states that the present invention is illustrated by the above examples of the process of the present invention, but the present invention is not limited to the above process steps, i.e. it is not meant that the present invention must rely on the above process steps to be carried out. It will be apparent to those skilled in the art that any modification of the present invention, equivalent substitutions of selected materials and additions of auxiliary components, selection of specific modes and the like, which are within the scope and disclosure of the present invention, are contemplated by the present invention.

Claims (2)

1. A natural herbal oral skin mucosa disinfection spray special for children is characterized by comprising the following formula (components and weight percentage): 1.0-1.5 of dandelion extract; 0.1-0.5 of plant stem cell essence; sweet orange peel oil 0.7-1.0; mint stem cells 0.1-0.5; 0.1-0.5 of chitosan derivative; 0.1-0.5 of sesamin; 0.1-0.5 of sow thistle flower extract; 1.0-1.5 of probiotics; 1.0-1.5 of honeysuckle extract; 0.1-0.5 of compound lysozyme; the pH was adjusted to 6.8 with natural citric acid and purified water was added to 100.

2. The preparation method of the natural herbal children special oral skin mucosa disinfection spray of claim 1 is characterized by comprising the following steps:

(1) preparing an oil phase component: respectively preparing herba Taraxaci extract, sweet orange peel oil, chitosan derivative, sesamin, herba Sonchi Oleracei extract, and flos Lonicerae extract at a certain proportion, and mixing;

(2) preparing an aqueous phase component: adding herba Menthae and plant stem cell essence into marigold essence water at a certain proportion, dissolving and stirring;

(3) heating the water phase component to 40 ℃, slowly adding the oil phase component, and emulsifying uniformly;

(4) cooling the components to 25 ℃, slowly adding the probiotics and the compound lysozyme, and uniformly stirring;

(5) using natural citric acid as an acid-base regulator, regulating the pH value of the solution to 6.0, and purifying water to 100;

(6) randomly performing spot inspection, subpackaging into spray bottles after the inspection is qualified, labeling and sealing.