CN110913864A - 一种稳定型烟酰胺核糖组合物及其制备方法 - Google Patents

一种稳定型烟酰胺核糖组合物及其制备方法 Download PDF

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Publication number
CN110913864A
CN110913864A CN201880037969.2A CN201880037969A CN110913864A CN 110913864 A CN110913864 A CN 110913864A CN 201880037969 A CN201880037969 A CN 201880037969A CN 110913864 A CN110913864 A CN 110913864A
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Prior art keywords
nicotinamide riboside
composition
nicotinamide
rebaudioside
salt
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CN201880037969.2A
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CN110913864B (zh
Inventor
傅荣昭
李振伟
郭杏林
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Bontac Bio-Engineering (shenzhen) Co ltd
Bontac Invitrolife Bio Technology Shenzhen Co ltd
Zhongshan Bangtai Hesheng Biotechnology Co ltd
Original Assignee
Bontac Invitrolife Bio Technology Shenzhen Co ltd
Jiangxi Bonzymes Biotechnology Co ltd
Bontac Bio-Engineering (shenzhen) Co ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Jellies, Jams, And Syrups (AREA)

Abstract

一种烟酰胺核糖组合物及其制备方法，该组合物包含烟酰胺核糖和/或其盐以及魔芋葡甘聚糖或莱鲍迪苷A。

Description

PCT国内申请，说明书已公开。

Claims (10)

  1. PCT国内申请，权利要求书已公开。
CN201880037969.2A 2018-08-17 2018-08-17 一种稳定型烟酰胺核糖组合物及其制备方法 Active CN110913864B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2018/101175 WO2019210607A1 (zh) 2018-08-17 2018-08-17 一种稳定型烟酰胺核糖组合物及其制备方法

Publications (2)

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CN110913864A true CN110913864A (zh) 2020-03-24
CN110913864B CN110913864B (zh) 2022-12-13

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Country Link
US (1) US11052100B2 (zh)
JP (1) JP6887025B2 (zh)
CN (1) CN110913864B (zh)
WO (1) WO2019210607A1 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111454311B (zh) * 2020-04-03 2021-10-19 深圳市迪克曼科技开发有限公司 烟酰胺核糖的有机酸盐及其组合物与制备方法

Citations (10)

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US3144412A (en) * 1960-11-01 1964-08-11 Colgate Palmolive Co Solid detergent compositions
CN102793265A (zh) * 2012-09-13 2012-11-28 中国烟草总公司郑州烟草研究院 一种天然烟草保润增香剂的制备方法及其在卷烟中的应用
US20130102771A1 (en) * 2010-07-06 2013-04-25 Hidenori KAMINISHI Neurite outgrowth agent
US20130165398A1 (en) * 2010-03-29 2013-06-27 Paul Hochegger Concentration-enhancing drink
US20140248411A1 (en) * 2011-11-23 2014-09-04 Korea Food Research Institute Sweetness enhancer
WO2015014958A1 (en) * 2013-07-31 2015-02-05 Dsm Ip Assets B.V. Stable sweetener compositions
CN105873937A (zh) * 2013-10-30 2016-08-17 可劳迈戴斯有限公司 用于在治疗皮肤病中局部使用的烟酰胺核苷组合物
CN106715451A (zh) * 2014-10-03 2017-05-24 康纳根有限公司 无热量甜味剂及合成方法
WO2018027070A1 (en) * 2016-08-04 2018-02-08 Seattle Gummy Company Compositions for athletic performance and methods of making and using thereof
WO2018089830A1 (en) * 2016-11-11 2018-05-17 The Queen's University Of Belfast Efficient and scalable syntheses of nicotinoyl ribosides and reduced nicotinoyl ribosides, modified derivatives thereof, phosphorylated analogs thereof, adenylyl dinucleotide conjugates thereof, and novel crystalline forms thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015099842A1 (en) * 2013-12-23 2015-07-02 Abbott Laboratories Hot beverage fortifier
US20160374908A1 (en) * 2015-06-29 2016-12-29 The Procter & Gamble Company Skin care composition and methods of using the same
US20210369674A1 (en) * 2016-08-04 2021-12-02 Seattle Gummy Company Health management compositions and methods of making and using thereof
CN106955290A (zh) * 2017-03-24 2017-07-18 南京顺昌医药科技有限公司 一种治疗退化性疾病的组合物及其用途

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3144412A (en) * 1960-11-01 1964-08-11 Colgate Palmolive Co Solid detergent compositions
US20130165398A1 (en) * 2010-03-29 2013-06-27 Paul Hochegger Concentration-enhancing drink
US20130102771A1 (en) * 2010-07-06 2013-04-25 Hidenori KAMINISHI Neurite outgrowth agent
US20140248411A1 (en) * 2011-11-23 2014-09-04 Korea Food Research Institute Sweetness enhancer
CN102793265A (zh) * 2012-09-13 2012-11-28 中国烟草总公司郑州烟草研究院 一种天然烟草保润增香剂的制备方法及其在卷烟中的应用
WO2015014958A1 (en) * 2013-07-31 2015-02-05 Dsm Ip Assets B.V. Stable sweetener compositions
CN105873937A (zh) * 2013-10-30 2016-08-17 可劳迈戴斯有限公司 用于在治疗皮肤病中局部使用的烟酰胺核苷组合物
CN106715451A (zh) * 2014-10-03 2017-05-24 康纳根有限公司 无热量甜味剂及合成方法
WO2018027070A1 (en) * 2016-08-04 2018-02-08 Seattle Gummy Company Compositions for athletic performance and methods of making and using thereof
WO2018089830A1 (en) * 2016-11-11 2018-05-17 The Queen's University Of Belfast Efficient and scalable syntheses of nicotinoyl ribosides and reduced nicotinoyl ribosides, modified derivatives thereof, phosphorylated analogs thereof, adenylyl dinucleotide conjugates thereof, and novel crystalline forms thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
SAMUEL AJ TRAMMELL ET AL.，: "Nicotinamide Riboside Is a Major NAD+ Precursor Vitamin in Cow Milk", 《THE JOURNAL OF NUTRITION》 *
马相杰等: "β-甘露聚糖酶水解酵母细胞壁水解条件的研究", 《食品科技》 *
魏巍: "烟酰胺凝胶的制备", 《中国医院药学杂志》 *

Also Published As

Publication number Publication date
JP2020526477A (ja) 2020-08-31
US20200323891A1 (en) 2020-10-15
JP6887025B2 (ja) 2021-06-16
WO2019210607A1 (zh) 2019-11-07
CN110913864B (zh) 2022-12-13
US11052100B2 (en) 2021-07-06

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