CN110806399A - Portable fluorescence immunoassay quantitative analyzer - Google Patents
Portable fluorescence immunoassay quantitative analyzer Download PDFInfo
- Publication number
- CN110806399A CN110806399A CN201910765828.9A CN201910765828A CN110806399A CN 110806399 A CN110806399 A CN 110806399A CN 201910765828 A CN201910765828 A CN 201910765828A CN 110806399 A CN110806399 A CN 110806399A
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- module
- control board
- reagent
- main control
- guide rail
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- 238000003018 immunoassay Methods 0.000 title claims abstract description 12
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 25
- 238000012545 processing Methods 0.000 claims abstract description 15
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 claims abstract description 13
- 229910052744 lithium Inorganic materials 0.000 claims abstract description 13
- 238000004891 communication Methods 0.000 claims abstract description 9
- 230000003287 optical effect Effects 0.000 claims description 15
- 238000001514 detection method Methods 0.000 abstract description 5
- 238000004458 analytical method Methods 0.000 abstract description 3
- 238000003745 diagnosis Methods 0.000 abstract description 2
- 230000035945 sensitivity Effects 0.000 abstract description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000007547 defect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000012921 fluorescence analysis Methods 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6402—Atomic fluorescence; Laser induced fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
The invention relates to a portable fluorescence immunoassay quantitative analyzer, which comprises a circuit main control board, a photoelectric processing module, a light path system, a reagent clamping groove, a thread sliding module, a reagent card, a direct current stepping motor, a fixed guide rail, a lithium battery, a mechanical part fixing plate, a thermal printer, an upright post screw, a capacitive touch screen, a GPRS communication module and other main parts, is mainly used for mobile rescue of ambulances and the like and instant diagnosis of clinics, and has the characteristics of simple structure, convenience in carrying, high sensitivity and movable interconnection of analysis and detection data.
Description
Technical Field
The invention relates to the technical field of in-vitro diagnosis fluorescence analysis, in particular to a portable fluorescence immunoassay quantitative analyzer.
Background
The existing fluorescence immunoassay quantitative analyzer has the defects of complicated equipment structure, inconvenient carrying due to the need of an external power supply, inconvenient data uploading, lower sensitivity and inaccurate detection result of substances with low concentration. The invention has simple structure, the built-in lithium battery can continuously work for more than 10 hours under the condition of no external power supply, the built-in GPRS wireless connection module can realize the instant transmission of data, and the more advanced light path system enables the equipment to detect the signal value with lower concentration.
Disclosure of Invention
In view of the above, the present invention provides a portable fluorescence immunoassay quantitative analyzer to solve the problems in the prior art.
In order to achieve the purpose, the invention provides the following technical scheme:
a portable fluorescence immunoassay quantitative analyzer comprises a circuit main control board, a photoelectric processing module, a light path system, a reagent clamping groove, a thread sliding module, a reagent card, a direct current stepping motor, a fixed guide rail, a lithium battery, a mechanical part fixing plate, a thermal printer, an upright screw, a capacitive touch screen and a GPRS communication module.
The direct current stepping motor, the fixed guide rail, the lithium battery and the thermal printer are sequentially fixed on the mechanical part fixing plate, the shaft end of the direct current stepping motor is connected with the threaded sliding module, and the threaded sliding module is connected with the fixed guide rail arranged in parallel on the motor shaft.
A reagent clamping groove is fixed on one side of the threaded sliding module, a reagent card is arranged in the reagent clamping groove, the reagent clamping groove moves synchronously on the fixed guide rail along with the threaded sliding module, and a sample to be detected is loaded on the reagent card.
The circuit main control board is arranged in parallel right above the mechanical part fixing plate and is fixedly connected with the mechanical part fixing plate through stand column screws, the photoelectric processing module and the light path system are arranged below the circuit main control board, and the circuit main control board, the photoelectric processing module, the direct current stepping motor, the lithium battery, the thermal printer, the capacitive touch screen and the GPRS communication module are electrically connected.
Preferably, the optical path system includes a light gathering bowl light source combination module, a first optical filter, a first convex lens, a plano-convex cylindrical lens, a reflective mirror, a photodiode, a second optical filter, a second convex lens, and a light gathering bowl, wherein the photodiode is electrically connected with the photoelectric processing module.
The invention has simple design, can detect a signal value with lower concentration, is intelligent and convenient to use, is convenient to carry for carrying and analyzing and detecting in time, and has the integral structure which is convenient for later maintenance.
Drawings
In order to more clearly illustrate the embodiments of the present invention, the drawings that are needed to be used in the description of the embodiments will be briefly described below, and it is apparent that the drawings in the following description are only embodiments of the present invention, and it is obvious to those skilled in the art that other drawings can be obtained from the provided drawings without inventive labor.
FIG. 1 is a schematic sectional view of a portable fluorescence immunoassay analyzer according to the present invention.
Labeled as:
the device comprises a circuit main control board 1, a photoelectric processing module 2, a light path system 3, a reagent clamping groove 4, a thread sliding module 5, a reagent card 6, a direct current stepping motor 7, a fixed guide rail 8, a lithium battery 9, a mechanical part fixing plate 10, a thermal printer 11, a stand column screw 12, a capacitive touch screen 13 and a GPRS communication module 14.
FIG. 2 is a schematic structural diagram of an optical path system of a portable fluorescence immunoassay quantitative analyzer according to the present invention.
Labeled as:
21 is a light source combination module of a light gathering bowl, 22 is a first optical filter, 23 is a first convex lens, 24 is a plano-convex cylindrical lens, 25 is a reflector, 26 is a photodiode, 27 is a second optical filter, 28 is a second convex lens, and 29 is a light gathering bowl.
Detailed Description
For the convenience of understanding, the technical solutions of the present invention will be described in detail and fully with reference to the accompanying drawings, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1, the portable fluorescence immunoassay quantitative analyzer provided by the present invention includes a circuit main control board 1, a photoelectric processing module 2, a light path system 3, a reagent card slot 4, a thread sliding module 5, a reagent card 6, a dc stepping motor 7, a fixed guide rail 8, a lithium battery 9, a mechanical component fixing plate 10, a thermal printer 11, a column screw 12, a capacitive touch screen 13, and a GPRS communication module 14.
The direct current stepping motor 7, the fixed guide rail 8, the lithium battery 9 and the thermal printer 11 are sequentially fixed on the mechanical part fixing plate 10, the shaft end of the direct current stepping motor 7 is connected with the thread sliding module 5, and the thread sliding module 5 is connected with the fixed guide rail arranged in parallel with the motor shaft 8. A reagent clamping groove 4 is fixed on one side of the threaded sliding module 5, a reagent card 6 is arranged in the reagent clamping groove 4, the reagent clamping groove 4 moves synchronously on the fixed guide rail along with the threaded sliding module 5, and a sample to be detected is loaded on the reagent card. The whole device is powered by a chargeable and dischargeable lithium battery 9, the direct-current stepping motor 7 controls the thread sliding module 5 to move, and the thermal printer 11 prints data of detection results.
The circuit main control board 1 is arranged in parallel right above the mechanical part fixing board 10 and is connected and fixed by four upright post screws 12 distributed at four corners, the photoelectric processing module 2 and the light path system 3 are arranged below the circuit main control board 1, and the circuit main control board 1, the photoelectric processing module 2, the direct current stepping motor 7, the lithium battery 9, the thermal printer 11, the capacitive touch screen 13 and the GPRS communication module 14 are electrically connected. The GPRS communication module can realize the instant transmission of the analysis detection data.
Preferably, the optical path system 3 includes a light gathering bowl light source combination module 21, a first optical filter 22, a first convex lens 23, a plano-convex cylindrical lens 24, a reflective mirror 25, a photodiode 26, a second optical filter 27, a second convex lens 28, and a light gathering bowl 29, where the photodiode 26 is electrically connected to the photoelectric processing module 2. The light source of the optical path system 3 is condensed by the light source combination module 21, then the first optical filter 22 filters out unwanted stray light, the unwanted stray light is further condensed by the first convex lens 23, then the parallel light with proper width is reduced by the plano-convex cylindrical lens 24, and the parallel light irradiates the line to be measured on the reagent card 6 at a proper angle through the reflector 25, so that the fluorescent substance is excited to emit fluorescence. The emitted fluorescence is condensed by a condensing bowl 29 positioned right above the line to be measured, further condensed by a second convex lens 28, filtered by a second optical filter 27 to remove stray light, and finally converted into an electric signal by a photodiode 26. The electric signal is processed by an amplifying circuit such as a triode on the photoelectric processing module 2, so that the signal is further amplified and then fed back to the circuit main control board 1, and analysis and detection data such as fluorescence intensity are obtained through calculation.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to the embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (2)
1. A portable fluorescence immunoassay quantitative analyzer is characterized by comprising a circuit main control board, a photoelectric processing module, a light path system, a reagent clamping groove, a thread sliding module, a reagent card, a direct current stepping motor, a fixed guide rail, a lithium battery, a mechanical part fixing plate, a thermal printer, a stand column screw, a capacitive touch screen and a GPRS communication module, wherein the direct current stepping motor, the fixed guide rail, the lithium battery and the thermal printer are sequentially fixed on the mechanical part fixing plate, the shaft end of the direct current stepping motor is connected with the thread sliding module, the thread sliding module is connected with the fixed guide rail which is arranged in parallel with a motor shaft, the reagent clamping groove is fixed on one side of the thread sliding module, the reagent card is arranged in the reagent clamping groove, the reagent clamping groove synchronously moves on the fixed guide rail along with the thread sliding module, the circuit main control board is arranged in parallel over the mechanical part fixing plate, by stand screwed connection is fixed, photoelectric processing module with light path system set up in circuit main control board below, circuit main control board, photoelectric processing module, direct current step motor, lithium cell, thermal printer, capacitive touch screen, GPRS communication module electric connection.
2. The portable fluorescence immunoassay quantitative analyzer of claim 1, wherein the optical system comprises a light-gathering bowl light source combination module, a first optical filter, a first convex lens, a plano-convex cylindrical lens, a reflective mirror, a photodiode, a second optical filter, a second convex lens and a light-gathering bowl, and the photodiode is electrically connected with the photoelectric processing module.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910765828.9A CN110806399A (en) | 2019-08-19 | 2019-08-19 | Portable fluorescence immunoassay quantitative analyzer |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910765828.9A CN110806399A (en) | 2019-08-19 | 2019-08-19 | Portable fluorescence immunoassay quantitative analyzer |
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| Publication Number | Publication Date |
|---|---|
| CN110806399A true CN110806399A (en) | 2020-02-18 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201910765828.9A Pending CN110806399A (en) | 2019-08-19 | 2019-08-19 | Portable fluorescence immunoassay quantitative analyzer |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113640508A (en) * | 2021-07-19 | 2021-11-12 | 安徽桐康医疗科技股份有限公司 | Detection plate for fluorescence immunoassay quantitative analyzer |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201438176U (en) * | 2009-07-13 | 2010-04-14 | 天津市兰标电子科技发展有限公司 | Sample fluorescence detection device |
| CN102087214A (en) * | 2010-12-31 | 2011-06-08 | 广州万孚生物技术有限公司 | Fluorescent quantitative detection instrument |
| CN103901190A (en) * | 2014-04-17 | 2014-07-02 | 武汉纽康度生物科技有限公司 | IF (immunofluorescence) quantitative analysis meter |
| CN104880450A (en) * | 2015-06-18 | 2015-09-02 | 苏州和迈精密仪器有限公司 | Line focusing detection system for immunofluorescence reagent card |
| CN107449765A (en) * | 2017-09-11 | 2017-12-08 | 基蛋生物科技股份有限公司 | A kind of biochemical immunity analyzer and biochemical immunity detection method |
| CN206756842U (en) * | 2017-05-21 | 2017-12-15 | 苏州和迈精密仪器有限公司 | A kind of handhold portable immunochromatographiassays assays instrument |
| CN108181456A (en) * | 2018-01-18 | 2018-06-19 | 南京岚煜生物科技有限公司 | Hand-held fluorescence immunoassay apparatus |
| CN210533992U (en) * | 2019-08-19 | 2020-05-15 | 湖南德荣生物医学工程有限公司 | Portable fluorescence immunoassay quantitative analyzer |
-
2019
- 2019-08-19 CN CN201910765828.9A patent/CN110806399A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201438176U (en) * | 2009-07-13 | 2010-04-14 | 天津市兰标电子科技发展有限公司 | Sample fluorescence detection device |
| CN102087214A (en) * | 2010-12-31 | 2011-06-08 | 广州万孚生物技术有限公司 | Fluorescent quantitative detection instrument |
| CN103901190A (en) * | 2014-04-17 | 2014-07-02 | 武汉纽康度生物科技有限公司 | IF (immunofluorescence) quantitative analysis meter |
| CN104880450A (en) * | 2015-06-18 | 2015-09-02 | 苏州和迈精密仪器有限公司 | Line focusing detection system for immunofluorescence reagent card |
| CN206756842U (en) * | 2017-05-21 | 2017-12-15 | 苏州和迈精密仪器有限公司 | A kind of handhold portable immunochromatographiassays assays instrument |
| CN107449765A (en) * | 2017-09-11 | 2017-12-08 | 基蛋生物科技股份有限公司 | A kind of biochemical immunity analyzer and biochemical immunity detection method |
| CN108181456A (en) * | 2018-01-18 | 2018-06-19 | 南京岚煜生物科技有限公司 | Hand-held fluorescence immunoassay apparatus |
| CN210533992U (en) * | 2019-08-19 | 2020-05-15 | 湖南德荣生物医学工程有限公司 | Portable fluorescence immunoassay quantitative analyzer |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113640508A (en) * | 2021-07-19 | 2021-11-12 | 安徽桐康医疗科技股份有限公司 | Detection plate for fluorescence immunoassay quantitative analyzer |
| CN113640508B (en) * | 2021-07-19 | 2024-02-27 | 安徽桐康医疗科技股份有限公司 | Detection plate for fluorescent immunity quantitative analyzer |
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