CN110785649A - 样本过滤装置 - Google Patents
样本过滤装置 Download PDFInfo
- Publication number
- CN110785649A CN110785649A CN201880042213.7A CN201880042213A CN110785649A CN 110785649 A CN110785649 A CN 110785649A CN 201880042213 A CN201880042213 A CN 201880042213A CN 110785649 A CN110785649 A CN 110785649A
- Authority
- CN
- China
- Prior art keywords
- sample
- filtering device
- sample filtering
- filter
- substrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000001914 filtration Methods 0.000 claims abstract description 184
- 239000000758 substrate Substances 0.000 claims abstract description 168
- 239000012528 membrane Substances 0.000 claims abstract description 154
- 239000012530 fluid Substances 0.000 claims abstract description 117
- 238000012360 testing method Methods 0.000 claims abstract description 100
- 239000012790 adhesive layer Substances 0.000 claims abstract description 91
- 238000003825 pressing Methods 0.000 claims abstract description 11
- 238000000034 method Methods 0.000 claims description 134
- 239000000706 filtrate Substances 0.000 claims description 77
- 210000004369 blood Anatomy 0.000 claims description 63
- 239000008280 blood Substances 0.000 claims description 63
- 239000000853 adhesive Substances 0.000 claims description 56
- 230000001070 adhesive effect Effects 0.000 claims description 56
- 238000004891 communication Methods 0.000 claims description 46
- 239000000463 material Substances 0.000 claims description 45
- 238000009826 distribution Methods 0.000 claims description 27
- 239000011148 porous material Substances 0.000 claims description 23
- 239000007853 buffer solution Substances 0.000 claims description 22
- -1 polypropylene Polymers 0.000 claims description 21
- 238000001514 detection method Methods 0.000 claims description 20
- 238000003018 immunoassay Methods 0.000 claims description 19
- 239000004743 Polypropylene Substances 0.000 claims description 16
- 238000004519 manufacturing process Methods 0.000 claims description 15
- 230000009467 reduction Effects 0.000 claims description 15
- 229920000515 polycarbonate Polymers 0.000 claims description 13
- 239000004417 polycarbonate Substances 0.000 claims description 13
- 238000007789 sealing Methods 0.000 claims description 13
- 230000009471 action Effects 0.000 claims description 12
- 238000002156 mixing Methods 0.000 claims description 12
- 229920001155 polypropylene Polymers 0.000 claims description 12
- 238000012545 processing Methods 0.000 claims description 11
- 229920001296 polysiloxane Polymers 0.000 claims description 10
- 229920001971 elastomer Polymers 0.000 claims description 9
- 239000005060 rubber Substances 0.000 claims description 9
- 239000004698 Polyethylene Substances 0.000 claims description 8
- 229920000728 polyester Polymers 0.000 claims description 8
- 229920000573 polyethylene Polymers 0.000 claims description 8
- 208000000412 Avitaminosis Diseases 0.000 claims description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 7
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 7
- 229930003827 cannabinoid Natural products 0.000 claims description 7
- 239000003557 cannabinoid Substances 0.000 claims description 7
- 239000002184 metal Substances 0.000 claims description 7
- 229910052751 metal Inorganic materials 0.000 claims description 7
- 229920002492 poly(sulfone) Polymers 0.000 claims description 7
- 230000003746 surface roughness Effects 0.000 claims description 7
- 230000004913 activation Effects 0.000 claims description 6
- 239000000919 ceramic Substances 0.000 claims description 6
- 229920003023 plastic Polymers 0.000 claims description 6
- 239000004033 plastic Substances 0.000 claims description 6
- 229920002725 thermoplastic elastomer Polymers 0.000 claims description 6
- 206010021135 Hypovitaminosis Diseases 0.000 claims description 5
- 208000030401 vitamin deficiency disease Diseases 0.000 claims description 5
- 229920001903 high density polyethylene Polymers 0.000 claims description 4
- 239000004700 high-density polyethylene Substances 0.000 claims description 4
- 229920001684 low density polyethylene Polymers 0.000 claims description 4
- 239000004702 low-density polyethylene Substances 0.000 claims description 4
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 claims description 3
- 229920012485 Plasticized Polyvinyl chloride Polymers 0.000 claims description 3
- 229910000831 Steel Inorganic materials 0.000 claims description 3
- 230000003213 activating effect Effects 0.000 claims description 3
- 229910052782 aluminium Inorganic materials 0.000 claims description 3
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 3
- 239000003153 chemical reaction reagent Substances 0.000 claims description 3
- 239000004814 polyurethane Substances 0.000 claims description 3
- 229920002635 polyurethane Polymers 0.000 claims description 3
- 239000010959 steel Substances 0.000 claims description 3
- 238000005304 joining Methods 0.000 claims 1
- 239000000523 sample Substances 0.000 description 141
- 238000013461 design Methods 0.000 description 34
- 210000004027 cell Anatomy 0.000 description 19
- 239000000203 mixture Substances 0.000 description 14
- 230000006870 function Effects 0.000 description 9
- 239000007788 liquid Substances 0.000 description 9
- 239000004820 Pressure-sensitive adhesive Substances 0.000 description 8
- 239000000872 buffer Substances 0.000 description 8
- 230000008569 process Effects 0.000 description 8
- 239000002131 composite material Substances 0.000 description 7
- 239000010410 layer Substances 0.000 description 7
- 230000003834 intracellular effect Effects 0.000 description 6
- 239000000047 product Substances 0.000 description 6
- 241000894006 Bacteria Species 0.000 description 5
- 230000000712 assembly Effects 0.000 description 5
- 238000000429 assembly Methods 0.000 description 5
- 230000008901 benefit Effects 0.000 description 5
- 238000005259 measurement Methods 0.000 description 5
- 230000007246 mechanism Effects 0.000 description 5
- 238000003556 assay Methods 0.000 description 4
- 230000000295 complement effect Effects 0.000 description 4
- 238000000151 deposition Methods 0.000 description 4
- 238000010790 dilution Methods 0.000 description 4
- 239000012895 dilution Substances 0.000 description 4
- 238000003780 insertion Methods 0.000 description 4
- 238000003756 stirring Methods 0.000 description 4
- 239000004094 surface-active agent Substances 0.000 description 4
- 238000003466 welding Methods 0.000 description 4
- 239000012491 analyte Substances 0.000 description 3
- 239000000427 antigen Substances 0.000 description 3
- 102000036639 antigens Human genes 0.000 description 3
- 108091007433 antigens Proteins 0.000 description 3
- 238000005452 bending Methods 0.000 description 3
- 238000009534 blood test Methods 0.000 description 3
- 230000006037 cell lysis Effects 0.000 description 3
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 3
- 230000037431 insertion Effects 0.000 description 3
- 238000002955 isolation Methods 0.000 description 3
- 230000013011 mating Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 239000002953 phosphate buffered saline Substances 0.000 description 3
- 229920001169 thermoplastic Polymers 0.000 description 3
- 239000004416 thermosoftening plastic Substances 0.000 description 3
- 238000012549 training Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 206010047627 Vitamin deficiencies Diseases 0.000 description 2
- 238000003491 array Methods 0.000 description 2
- 239000000090 biomarker Substances 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 2
- 230000009089 cytolysis Effects 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 230000000994 depressogenic effect Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 230000005611 electricity Effects 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 201000004792 malaria Diseases 0.000 description 2
- 150000002739 metals Chemical class 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 238000000465 moulding Methods 0.000 description 2
- 235000018102 proteins Nutrition 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 238000012113 quantitative test Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 239000006228 supernatant Substances 0.000 description 2
- 241000282472 Canis lupus familiaris Species 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 238000007400 DNA extraction Methods 0.000 description 1
- 208000003917 Dirofilariasis Diseases 0.000 description 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 1
- 241000283086 Equidae Species 0.000 description 1
- 241000713730 Equine infectious anemia virus Species 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- 208000031886 HIV Infections Diseases 0.000 description 1
- 208000037357 HIV infectious disease Diseases 0.000 description 1
- 241000590002 Helicobacter pylori Species 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- 206010019973 Herpes virus infection Diseases 0.000 description 1
- XQFRJNBWHJMXHO-RRKCRQDMSA-N IDUR Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(I)=C1 XQFRJNBWHJMXHO-RRKCRQDMSA-N 0.000 description 1
- 102000009151 Luteinizing Hormone Human genes 0.000 description 1
- 108010073521 Luteinizing Hormone Proteins 0.000 description 1
- 241000002163 Mesapamea fractilinea Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 208000000821 Parathyroid Neoplasms Diseases 0.000 description 1
- 102000003982 Parathyroid hormone Human genes 0.000 description 1
- 108090000445 Parathyroid hormone Proteins 0.000 description 1
- 206010033964 Parathyroid tumour benign Diseases 0.000 description 1
- 229920001213 Polysorbate 20 Polymers 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 206010060862 Prostate cancer Diseases 0.000 description 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 description 1
- 206010040047 Sepsis Diseases 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 229920004890 Triton X-100 Polymers 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 239000002313 adhesive film Substances 0.000 description 1
- 235000021120 animal protein Nutrition 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 229920005601 base polymer Polymers 0.000 description 1
- 239000012472 biological sample Substances 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 239000007767 bonding agent Substances 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 238000003776 cleavage reaction Methods 0.000 description 1
- 238000005056 compaction Methods 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 229940109239 creatinine Drugs 0.000 description 1
- 238000012864 cross contamination Methods 0.000 description 1
- 238000009295 crossflow filtration Methods 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 238000012938 design process Methods 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 208000009724 equine infectious anemia Diseases 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 229940037467 helicobacter pylori Drugs 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 231100000283 hepatitis Toxicity 0.000 description 1
- 208000005252 hepatitis A Diseases 0.000 description 1
- 208000002672 hepatitis B Diseases 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 238000010329 laser etching Methods 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 229940040129 luteinizing hormone Drugs 0.000 description 1
- 230000002934 lysing effect Effects 0.000 description 1
- 240000004308 marijuana Species 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 150000002825 nitriles Chemical class 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 238000012354 overpressurization Methods 0.000 description 1
- 230000016087 ovulation Effects 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 201000003686 parathyroid adenoma Diseases 0.000 description 1
- 208000014643 parathyroid gland adenoma Diseases 0.000 description 1
- 239000000199 parathyroid hormone Substances 0.000 description 1
- 229960001319 parathyroid hormone Drugs 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 description 1
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 1
- 229920000379 polypropylene carbonate Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 238000009597 pregnancy test Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000002331 protein detection Methods 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 239000003566 sealing material Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/492—Determining multiple analytes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
- B01L2300/042—Caps; Plugs
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/046—Function or devices integrated in the closure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/12—Specific details about materials
- B01L2300/123—Flexible; Elastomeric
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0605—Valves, specific forms thereof check valves
- B01L2400/0616—Ball valves
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
- G01N2001/4088—Concentrating samples by other techniques involving separation of suspended solids filtration
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Ecology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Clinical Laboratory Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762525039P | 2017-06-26 | 2017-06-26 | |
| US62/525,039 | 2017-06-26 | ||
| PCT/US2018/039556 WO2019005833A1 (en) | 2017-06-26 | 2018-06-26 | SAMPLE FILTERING DEVICE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110785649A true CN110785649A (zh) | 2020-02-11 |
Family
ID=64741868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201880042213.7A Pending CN110785649A (zh) | 2017-06-26 | 2018-06-26 | 样本过滤装置 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11946843B2 (enExample) |
| EP (1) | EP3645998B1 (enExample) |
| JP (1) | JP2020525802A (enExample) |
| CN (1) | CN110785649A (enExample) |
| WO (1) | WO2019005833A1 (enExample) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111420622A (zh) * | 2020-04-30 | 2020-07-17 | 南通合瑞源生物科技有限公司 | 一种用于核酸合成纯化高通量多孔过滤板 |
| CN112858085A (zh) * | 2021-01-19 | 2021-05-28 | 竹简云(天津)生物科技有限公司 | 一种食品药物溶解度检测分析装置 |
| CN113252765A (zh) * | 2021-06-21 | 2021-08-13 | 南昌大学 | 毛细管电泳仪 |
| US11612888B2 (en) | 2017-01-04 | 2023-03-28 | The Research Foundation For The State University Of New York | Biomarker detection device |
| CN115950868A (zh) * | 2022-12-26 | 2023-04-11 | 深圳市雷诺华科技实业有限公司 | 一种抗体-斑点法进行糖化白蛋白测定的测试装置及其测试方法 |
| CN116124561A (zh) * | 2022-12-30 | 2023-05-16 | 广州安必平自动化检测设备有限公司 | 一种样本瓶及其使用方法 |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11596943B2 (en) * | 2018-07-25 | 2023-03-07 | Canon Virginia, Inc. | Multi hole inlet structure |
| USD920534S1 (en) | 2018-12-21 | 2021-05-25 | CanaryQ, Inc. | Blood sample filtration device |
| CN113908898B (zh) * | 2021-11-18 | 2025-03-28 | 鲲鹏基因(北京)科学仪器有限公司 | 设有阻隔滤芯的防污染密封盖、多腔室样本制备装置 |
| JP2025503439A (ja) | 2021-12-17 | 2025-02-04 | アボット・ラボラトリーズ | 血液試料におけるｕｃｈ－ｌ１、ｇｆａｐ及び他のバイオマーカーを決定するためのシステム及び方法 |
| CN114323803B (zh) * | 2022-03-08 | 2022-05-20 | 潍坊市奎文区园林环卫服务中心 | 一种园林生态管理用水质取样装置 |
| CN115138406B (zh) * | 2022-06-15 | 2024-05-24 | 安徽福贸生物科技有限公司 | 一种便于消杀的医用微流控芯片进样过滤装置 |
| WO2024006876A1 (en) | 2022-06-29 | 2024-01-04 | Abbott Laboratories | Magnetic point-of-care systems and assays for determining gfap in biological samples |
| CN116493058A (zh) * | 2023-03-03 | 2023-07-28 | 重庆威科贝科技有限公司 | 样本容器 |
| CN121001821A (zh) * | 2023-04-10 | 2025-11-21 | 贝克顿·迪金森公司 | 过滤用于核酸扩增的粗样品的系统和方法 |
| USD1069156S1 (en) | 2023-04-10 | 2025-04-01 | Becton, Dickinson And Company | Dispensing device |
| GB202318356D0 (en) * | 2023-11-30 | 2024-01-17 | Osler Diagnostics Ltd | Liquid collection device and liquid handling device configured to receive a liquid collection device |
| WO2025211313A1 (ja) * | 2024-04-01 | 2025-10-09 | 内田技研株式会社 | 情報処理装置、情報管理方法、コンピュータプログラム、および、検体採取キット |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4761230A (en) * | 1987-06-11 | 1988-08-02 | Millipore Corporation | Small volume tangential flow filtration apparatus |
| CN1169886A (zh) * | 1996-01-19 | 1998-01-14 | 富士胶片公司 | 血液过滤器 |
| WO2002062942A2 (en) * | 2001-02-06 | 2002-08-15 | Pall Corporation | Filtration assembly |
| US20110266160A1 (en) * | 2009-01-08 | 2011-11-03 | James Gordon Campbell | Method and apparatus for alcohol concentration detection in a blood sample |
| CN102791616A (zh) * | 2009-12-23 | 2012-11-21 | 西托维拉公司 | 用于粒子过滤的系统和方法 |
| CN102803958A (zh) * | 2009-06-17 | 2012-11-28 | 白血球保健股份有限公司 | 血液过滤器以及过滤血液的方法 |
| CN103038624A (zh) * | 2010-07-14 | 2013-04-10 | 恰根有限公司 | 一种新型的贮存、收集或分离用装置 |
| US20140080112A1 (en) * | 2012-02-13 | 2014-03-20 | Streck, Inc. | Blood collection device for improved nucleic acid regulation |
| CN105874052A (zh) * | 2013-11-04 | 2016-08-17 | 查尔斯河实验室公司 | 过滤系统和其使用 |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3939822A (en) | 1974-08-14 | 1976-02-24 | Jack Markowitz | Disposable blood collection and filtering device |
| BE849898A (fr) | 1976-12-28 | 1977-06-28 | Dispositif de dilution et de filtration | |
| DE3037898A1 (de) * | 1980-10-07 | 1982-05-06 | Bruker Analytische Meßtechnik GmbH, 7512 Rheinstetten | Mischkammer |
| US4915847A (en) | 1987-08-04 | 1990-04-10 | Baxter International Inc. | Cryoglobulin separation |
| USD305934S (en) | 1986-11-27 | 1990-02-06 | Terumo Kabushiki Kaisha | Filter for treating blood |
| US4828716A (en) | 1987-04-03 | 1989-05-09 | Andronic Devices, Ltd. | Apparatus and method for separating phases of blood |
| NL8800796A (nl) * | 1988-03-29 | 1989-10-16 | X Flow Bv | Werkwijze voor de chemische analyse van bestanddelen van een lichaamsvloeistof, alsmede een testinrichting en testpakket voor een dergelijke analyse. |
| US4976851A (en) | 1988-06-06 | 1990-12-11 | Terumo Kabushiki Kaisha | Liquid separator |
| GB2232599A (en) | 1989-06-08 | 1990-12-19 | Summers Dr Julie Andrea | One-step blood to plasma device |
| USD355973S (en) | 1993-02-10 | 1995-02-28 | Terumo Kabushiki Kaisha | Blood filter |
| DK1021715T3 (da) | 1996-02-09 | 2002-10-21 | Micro Diagnostic Innovations N | Fremgangsmåde og kit til adskillelse af plasma af fuldblod |
| USD403975S (en) | 1997-06-17 | 1999-01-12 | Mercury Diagnostics, Inc. | Test strip device |
| US7745106B2 (en) | 1997-06-24 | 2010-06-29 | Cascade Medical Enterprises, Llc | Methods and devices for separating liquid components |
| JP2000074906A (ja) | 1998-09-01 | 2000-03-14 | Fuji Photo Film Co Ltd | 簡易血液濾過点着器 |
| EP1208189B1 (en) | 1999-05-28 | 2004-10-06 | Cepheid | Device and method for analysing liquid samples |
| JP2001299730A (ja) * | 2000-04-21 | 2001-10-30 | Fuji Photo Film Co Ltd | 血漿採取具 |
| US20020058030A1 (en) | 2000-05-03 | 2002-05-16 | Eligix, Inc. | Whole blood separator apparatus and method of use |
| JP2001321368A (ja) | 2000-05-16 | 2001-11-20 | Fuji Photo Film Co Ltd | 血漿採取具 |
| US6632681B1 (en) | 2000-07-24 | 2003-10-14 | Ey Laboratories | Reagent delivery device and method of use |
| AU151377S (en) | 2002-06-10 | 2003-04-04 | Daiichi Pure Chemicals Co Ltd | Device for test of specimen |
| US7093507B2 (en) * | 2003-05-12 | 2006-08-22 | Bel-Art Products, Inc. | Pipette control arrangement |
| JP2006118936A (ja) * | 2004-10-20 | 2006-05-11 | Denka Seiken Co Ltd | メンブランエンザイムイムノアッセイ法 |
| USD566291S1 (en) | 2005-05-03 | 2008-04-08 | Handylab, Inc. | Microfluidic cartridge |
| KR20100111097A (ko) * | 2009-04-06 | 2010-10-14 | 삼성전자주식회사 | 표적물질 분리를 위한 미세유동장치 및 그 정제방법 |
| USD642908S1 (en) | 2009-11-17 | 2011-08-09 | Help Remedies, Inc. | Container |
| AU2013204820B2 (en) | 2009-12-23 | 2014-01-30 | Cytovera, Inc. | A System and Method for Particle Filtration |
| US8388566B2 (en) | 2010-04-29 | 2013-03-05 | Sorin Group Italia, S.r.l. | Oxygenator with integrated arterial filter including filter frame |
| US8846333B2 (en) | 2010-06-10 | 2014-09-30 | Hemcheck Sweden Ab | Method and device for visual detection of hemolysis |
| KR101749243B1 (ko) * | 2010-12-06 | 2017-06-21 | 한국전자통신연구원 | 자기력을 이용한 혈장 분리 방법 및 장치 |
| SE536634C2 (sv) | 2011-12-09 | 2014-04-15 | Hemcheck Sweden Ab | Anordning för detektion av hemolys |
| CN104066514B (zh) * | 2012-01-24 | 2017-07-28 | 皇家飞利浦有限公司 | 用于筒的过滤单元 |
| USD734467S1 (en) | 2014-03-24 | 2015-07-14 | Fenwal, Inc. | Blood filter |
| US10111610B2 (en) | 2014-11-04 | 2018-10-30 | Wainamics, Inc. | Microscale plasma separator |
| USD772427S1 (en) | 2015-04-28 | 2016-11-22 | University Of British Columbia | Microfluidic cartridge |
| USD771834S1 (en) | 2015-04-28 | 2016-11-15 | University Of British Columbia | Microfluidic cartridge |
| USD771833S1 (en) | 2015-04-28 | 2016-11-15 | University Of British Columbia | Microfluidic cartridge |
| PL3272760T3 (pl) | 2016-07-19 | 2019-10-31 | Evonik Degussa Gmbh | Ligandy 1,1'-bis(fosfino)ferrocenowe dla alkoksykarbonylowania |
| DE102017125881B4 (de) * | 2017-11-06 | 2019-06-19 | Sartorius Stedim Biotech Gmbh | Filtermodul und Verfahren zum Nachweis von Mirkoorganismen |
| JP1610170S (enExample) | 2017-11-10 | 2018-07-30 | ||
| USD875271S1 (en) | 2018-08-03 | 2020-02-11 | Vdi Laboratory, Llc. | Collection and storage case for dry blood samples |
-
2018
- 2018-06-26 CN CN201880042213.7A patent/CN110785649A/zh active Pending
- 2018-06-26 WO PCT/US2018/039556 patent/WO2019005833A1/en not_active Ceased
- 2018-06-26 EP EP18823246.6A patent/EP3645998B1/en active Active
- 2018-06-26 JP JP2020520436A patent/JP2020525802A/ja active Pending
- 2018-06-26 US US16/625,799 patent/US11946843B2/en active Active
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4761230A (en) * | 1987-06-11 | 1988-08-02 | Millipore Corporation | Small volume tangential flow filtration apparatus |
| CN1169886A (zh) * | 1996-01-19 | 1998-01-14 | 富士胶片公司 | 血液过滤器 |
| WO2002062942A2 (en) * | 2001-02-06 | 2002-08-15 | Pall Corporation | Filtration assembly |
| US20110266160A1 (en) * | 2009-01-08 | 2011-11-03 | James Gordon Campbell | Method and apparatus for alcohol concentration detection in a blood sample |
| CN102803958A (zh) * | 2009-06-17 | 2012-11-28 | 白血球保健股份有限公司 | 血液过滤器以及过滤血液的方法 |
| CN102791616A (zh) * | 2009-12-23 | 2012-11-21 | 西托维拉公司 | 用于粒子过滤的系统和方法 |
| CN103038624A (zh) * | 2010-07-14 | 2013-04-10 | 恰根有限公司 | 一种新型的贮存、收集或分离用装置 |
| US20140080112A1 (en) * | 2012-02-13 | 2014-03-20 | Streck, Inc. | Blood collection device for improved nucleic acid regulation |
| CN105874052A (zh) * | 2013-11-04 | 2016-08-17 | 查尔斯河实验室公司 | 过滤系统和其使用 |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11612888B2 (en) | 2017-01-04 | 2023-03-28 | The Research Foundation For The State University Of New York | Biomarker detection device |
| CN111420622A (zh) * | 2020-04-30 | 2020-07-17 | 南通合瑞源生物科技有限公司 | 一种用于核酸合成纯化高通量多孔过滤板 |
| CN112858085A (zh) * | 2021-01-19 | 2021-05-28 | 竹简云(天津)生物科技有限公司 | 一种食品药物溶解度检测分析装置 |
| CN112858085B (zh) * | 2021-01-19 | 2021-11-02 | 竹简云(天津)生物科技有限公司 | 一种食品药物溶解度检测分析装置 |
| CN113252765A (zh) * | 2021-06-21 | 2021-08-13 | 南昌大学 | 毛细管电泳仪 |
| CN115950868A (zh) * | 2022-12-26 | 2023-04-11 | 深圳市雷诺华科技实业有限公司 | 一种抗体-斑点法进行糖化白蛋白测定的测试装置及其测试方法 |
| CN115950868B (zh) * | 2022-12-26 | 2024-02-13 | 深圳市雷诺华科技实业有限公司 | 一种抗体-斑点法进行糖化白蛋白测定的测试装置及其测试方法 |
| CN116124561A (zh) * | 2022-12-30 | 2023-05-16 | 广州安必平自动化检测设备有限公司 | 一种样本瓶及其使用方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20200124508A1 (en) | 2020-04-23 |
| EP3645998B1 (en) | 2023-11-15 |
| US11946843B2 (en) | 2024-04-02 |
| JP2020525802A (ja) | 2020-08-27 |
| EP3645998A4 (en) | 2021-07-14 |
| EP3645998A1 (en) | 2020-05-06 |
| WO2019005833A1 (en) | 2019-01-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP3645998B1 (en) | Sample filtration device and method | |
| JP4513085B2 (ja) | 試料の容器 | |
| US10589265B2 (en) | Reagent storage in microfluidic systems and related articles and methods | |
| CN108745429B (zh) | 一种多通道快速检测微流体检测芯片 | |
| KR102090934B1 (ko) | 마이크로유체 반응기 시스템 | |
| CN111282607B (zh) | 用于样品流体分析的一次性盒 | |
| JP2020525802A5 (enExample) | ||
| CN105992648A (zh) | 用于制备含有用于分析的细胞的样品流体的盒 | |
| WO2024067695A1 (zh) | 微流控芯片及检测方法 | |
| CA2664449A1 (en) | Cartridge system | |
| CN102844659A (zh) | 血球分离芯片 | |
| CN109746059B (zh) | 微液滴生成系统 | |
| CN108339578B (zh) | 液滴进样器以及使用其的液滴进样方法 | |
| CN113351267B (zh) | 应用于微流控芯片之快速拆接之密封匹配接头模块及其操作平台 | |
| JP2014124097A (ja) | 核酸分析用カートリッジ及び核酸分析装置 | |
| KR102521127B1 (ko) | 미세유체 혼합 장치 및 방법 | |
| CN113441194B (zh) | 一种微流控检测芯片 | |
| MXPA01000691A (es) | Extraccion mediante un fluido de muestras microdisectadas. | |
| CN116099578A (zh) | 微流控检测芯片 | |
| CN101199917A (zh) | 微射流系统中的微射流部件的实现 | |
| CN222624596U (zh) | 一种用于生物晶片检测的晶片卡匣 | |
| CN120981294A (zh) | 异种物质混合分装装置 | |
| JP2010151716A (ja) | 使い捨て式流体導入装置 | |
| HK1162391B (en) | Improved reagent storage in microfluidic systems and related articles and methods | |
| HK1162391A (en) | Improved reagent storage in microfluidic systems and related articles and methods |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20200211 |