CN110693997A - Preparation for removing putrefaction and promoting granulation of scald and burn and preparation method thereof - Google Patents

Preparation for removing putrefaction and promoting granulation of scald and burn and preparation method thereof Download PDF

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CN110693997A
CN110693997A CN201911250775.3A CN201911250775A CN110693997A CN 110693997 A CN110693997 A CN 110693997A CN 201911250775 A CN201911250775 A CN 201911250775A CN 110693997 A CN110693997 A CN 110693997A
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parts
preparation
scald
burn
honeysuckle
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陈石泉
聂勤麒
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/64—Insects, e.g. bees, wasps or fleas
    • A61K35/644—Beeswax; Propolis; Royal jelly; Honey
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718—Coptis (goldthread)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/756—Phellodendron, e.g. corktree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8965—Asparagus, e.g. garden asparagus or asparagus fern
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

The invention discloses a preparation for removing putrefaction and promoting granulation of scalds and burns and a preparation method thereof, wherein the bacteriostatic preparation comprises the following substances in parts by mass: 90-110 parts of giant knotweed, 90-110 parts of honeysuckle, 210 parts of asparagus 190-. The invention has stronger functions of clearing heat, cooling blood, diminishing inflammation, detoxifying, dissipating blood stasis, relieving pain, eliminating furuncle, removing lumps, sterilizing and inhibiting bacteria, can quickly cure wounds caused by burn, scald and the like, eliminates scars, has stronger antibacterial and bacteriostatic effects on pyogenic cocci such as staphylococcus aureus, escherichia coli, fungi such as candida albicans and other pathogenic bacteria which affect skin health, and has obvious effects on wound wounds such as burn, scald, bruise, incised wound and the like or treating hypertrophic scars.

Description

Preparation for removing putrefaction and promoting granulation of scald and burn and preparation method thereof
Technical Field
The invention relates to the field of traditional Chinese medicines, in particular to a preparation for removing putrefaction and promoting granulation for scalds and burns and a preparation method of the preparation.
Background
The most common antibacterial drugs for treating burns, scalds and the like in the market at present mainly comprise two types, one type is an external drug preparation prepared from chemical antibacterial drugs, and the other type is an external antibacterial drug for wounds at present and is clinically used for the wounds, for example, the external drug for treating burns and scalds at present takes the principles of calming, relieving itching and moistening skin, for example, lincomycin lidocaine is usually selected, and skin atrophy, capillary vessel dilatation and dependence are caused by long-term use, so that proper or intermittent medication is required; and for example, chlorhexidine acetate is an antibacterial drug, but the antibacterial effect is not ideal for killing, preventing and treating skin, mucosal bacteria, or fungal infection, or mixed infection of bacteria and fungi, and the antibacterial effect is usually exerted only when the antibacterial concentration is higher, the antibacterial effect is slow, the antibacterial effect can be better exerted after 3 minutes, the retention effective time of skin and mucosa is shorter, the antibacterial effect at low concentration is also poor, and the chemical drug has more obvious irritation when the antibacterial concentration is higher to achieve the wound treatment effect, such as the irritation, the dry and astringent feeling and other adverse reactions, and some adverse reactions even generate dependence. The other is an external preparation made of traditional Chinese medicines, along with the increasing requirements of people on health, sanitation and safety, more and more consumers favor antibacterial preparations combined by various Chinese herbal medicines and the like, but most of the existing traditional Chinese medicine scald ointments are made of Chinese herbal medicine preparations, have no toxicity and side effects, remove the necrotic tissue and promote granulation, repair damaged tissues well, have certain curative effects on scald, but have not particularly remarkable curative effects, long treatment time and slow wound healing, and cause infection in the process of scratching due to itching in the healing process and leave scars due to different scald degrees after healing.
Disclosure of Invention
The invention aims to: in order to solve the problems in the prior art in the background art, the preparation for removing the necrotic tissue and promoting granulation for the scalds and the burns and the preparation method are provided.
The technical scheme adopted by the invention for solving the technical problems is as follows:
a preparation for removing putrefaction and promoting granulation for scald and burn comprises the following components in parts by mass: 90-110 parts of giant knotweed, 90-110 parts of honeysuckle, 210 parts of asparagus 190-.
Preferably, the composition comprises the following components in parts by mass: 100 parts of giant knotweed, 100 parts of honeysuckle, 200 parts of asparagus, 100 parts of coptis, 100 parts of scutellaria, 100 parts of phellodendron, 2000 parts of sesame oil, 100 parts of beeswax and 50 parts of borneol.
A preparation method of a preparation for removing putrefaction and promoting granulation for scald and burn comprises the following steps:
(1) after removing impurities and cleaning all the medicinal materials, weighing 100 g of giant knotweed, 100 g of honeysuckle, 200 g of asparagus, 100 g of coptis, 100 g of scutellaria and 100 g of phellodendron for later use according to the mixture ratio;
(2) pulverizing the raw materials into 50-200 mesh powder;
(3) mixing the pulverized medicinal materials, adding 2000ml of purified water, soaking for 25-45min, decocting for 55-65min in a stainless steel pot, filtering to obtain the first filtrate, adding 2000ml of purified water into the residue, decocting for 55-65min, filtering to obtain the second filtrate, mixing the two filtrates, and concentrating to 700ml to obtain concentrated solution A;
(4) and (3) taking 2000 g of sesame oil, refining into 1150 g, adding 100 g of beeswax and 50 g of borneol to obtain a mixed solution B, uniformly stirring, adding the concentrated solution B, fully and uniformly stirring, and cooling to room temperature to obtain the antibacterial preparation.
Preferably, the medicinal materials are crushed into 50-100 meshes of powder in the step (2).
Preferably, the crude drugs are decocted in purified water in the step (3) with stirring for 1min every 15 min.
The polygonum cuspidatum in the raw materials can clear away heat and toxic materials, stop bleeding by astringency and dissipate blood stasis, and is mainly used for treating wounds caused by burn, scald, bruise, incised wound and the like.
Honeysuckle flower, flos Lonicerae, for its actions of clearing away heat and toxic material, dispelling wind-heat. Can be used for treating carbuncle, furuncle, sore throat, erysipelas, toxic heat, dysentery, wind-heat type common cold, epidemic febrile disease, and fever.
Tian Dong can nourish yin, moisten dryness, clear lung heat and promote fluid production. Can be used for treating dry cough due to lung dryness, cough with sticky phlegm, soreness of waist and knees, hectic fever due to yin-heat, thirst due to internal heat, fluid injury due to fever, dry throat, thirst, and constipation due to intestinal dryness; modern medicine proves that the decoction has different degrees of bacteriostatic action on bacillus anthracis, alpha and heterotypic hemolytic streptococcus, diphtheria bacillus, diphtheroids, pneumococci, staphylococcus aureus, staphylococcus limosum, staphylococcus albus, bacillus subtilis and the like when used in vitro.
Coptis root, rhizoma Coptidis clears heat and dampness, purges fire and detoxifies. Can be used for treating damp-heat distention and fullness, emesis, acid regurgitation, dysentery, jaundice, hyperpyrexia, excessive heart-fire, vexation, insomnia, palpitation, hematemesis, epistaxis, conjunctival congestion, toothache, diabetes, carbuncle, swelling, and furuncle; it is used externally to treat eczema, eczema and purulent ear canal.
Baikal skullcap root, also called camellia root, and Tujin tea root, is used as the drug by root. Has the effects of clearing heat, eliminating dampness, cooling blood, preventing miscarriage and detoxifying. It can be used for treating epidemic febrile disease, upper respiratory infection, cough due to lung heat, yellow gallbladder due to damp-heat, pneumonia, dysentery, hemoptysis, conjunctival congestion, threatened abortion, hypertension, carbuncle, furuncle, and sore. The clinical application of the scutellaria baicalensis has better antibacterial property than the coptis chinensis, and the scutellaria baicalensis does not generate drug resistance.
Phellodendron bark, cortex Phellodendri, radix Et rhizoma Rhei, cortex Phellodendri, radix Angelicae sinensis, radix Glycyrrhizae, rhizoma Atractylodis Macrocephalae, and cortex Phellodendri, has effects in clearing away heat, eliminating dampness, purging pathogenic fire, removing steam, removing toxic materials, and treating sore. Can be used for treating damp-heat dysentery, jaundice, dark urine, leukorrhagia, pudendal pruritus, pyretic stranguria, pain, tinea pedis, atrophy 36484, hectic fever, night sweat, spermatorrhea, pyocutaneous disease, toxic swelling, eczema, and eczema.
The borneol is colorless transparent or white semitransparent crisp crystal, has faint scent, pungent, cool, bitter and cold taste, enters heart channel, lung channel and faint scent honey powder.
The inventor finds that the combination of giant knotweed rhizome, honeysuckle flower, asparagus, coptis root, scutellaria baicalensis, golden cypress and borneol can quickly cure wounds caused by various burns and scalds, prevent and treat wound infection and expansion, quickly converge the wounds, finally can basically eliminate scars after the wound healing, and has the effect that each component does not have when being applied independently.
Compared with the prior art, the invention has the following beneficial effects:
(1) the invention has stronger functions of clearing heat, cooling blood, diminishing inflammation, detoxifying, dissipating blood stasis, relieving pain, eliminating furuncle, removing tumor, sterilizing and inhibiting bacteria, can quickly cure wounds caused by burn, scald and the like, and effectively eliminates hyperplastic scars;
(2) the invention has stronger antibacterial and bacteriostatic effects on pyogenic cocci which influence the health of skin, such as bacillus anthracis, alpha-type and heterotypic hemolytic streptococcus, corynebacterium diphtheriae, diphtheria-like bacillus, pneumococcus, staphylococcus aureus, staphylococcus citreus, staphylococcus albus, bacillus subtilis, escherichia coli, fungi such as candida albicans and other pathogenic bacteria, and has obvious effect on wound wounds such as burns, scalds, abrasions, incised wounds and the like or hyperplastic scars;
(3) the invention has good antibacterial and healing promoting effects and low price, not only effectively relieves the pain of patients, but also economically reduces the trouble of the masses.
Detailed Description
In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further explained by combining the specific embodiments.
Example 1
A preparation for removing putrefaction and promoting granulation for scald and burn comprises the following components in parts by mass: 100 parts of giant knotweed, 100 parts of honeysuckle, 200 parts of asparagus, 100 parts of coptis, 100 parts of scutellaria, 100 parts of phellodendron, 2000 parts of sesame oil, 100 parts of beeswax and 50 parts of borneol.
A preparation method of a preparation for removing putrefaction and promoting granulation for scald and burn comprises the following steps:
(1) after removing impurities and cleaning all the medicinal materials, weighing 100 g of giant knotweed, 100 g of honeysuckle, 200 g of asparagus, 100 g of coptis, 100 g of scutellaria and 100 g of phellodendron for later use according to the mixture ratio;
(2) pulverizing the raw materials into 50-100 mesh powder;
(3) mixing the pulverized medicinal materials, adding 2000ml of purified water, soaking for 30min, heating and decocting for 60min in a stainless steel pot, filtering to obtain a first filtrate, adding 2000ml of purified water into the residue, heating and decocting for 60min, filtering to obtain a second filtrate, mixing the two filtrates, and concentrating to 700ml to obtain a concentrated solution A;
(4) and (3) taking 2000 g of sesame oil, refining into 1150 g, adding 100 g of beeswax and 50 g of borneol to obtain a mixed solution B, uniformly stirring, adding the concentrated solution B, fully and uniformly stirring, and cooling to room temperature to obtain the antibacterial preparation.
Preferably, the crude drugs are decocted in purified water in the step (3) with stirring for 1min every 15 min.
Example 2
A preparation for removing putrefaction and promoting granulation for scald and burn comprises the following components in parts by mass: 90-110 parts of giant knotweed, 90-110 parts of honeysuckle, 210 parts of asparagus 190-.
A preparation method of a preparation for removing putrefaction and promoting granulation for scald and burn comprises the following steps:
(1) after removing impurities and cleaning all the medicinal materials, weighing 100 g of giant knotweed, 100 g of honeysuckle, 200 g of asparagus, 100 g of coptis, 100 g of scutellaria and 100 g of phellodendron for later use according to the mixture ratio;
(2) pulverizing the raw materials into 50-100 mesh powder;
(3) mixing the pulverized medicinal materials, adding 2000ml of purified water, soaking for 25min, heating and decocting for 55min in a stainless steel pot, filtering to obtain a first filtrate, adding 2000ml of purified water into the residue, heating and decocting for 55min, filtering to obtain a second filtrate, mixing the two filtrates, and concentrating to 700ml to obtain a concentrated solution A;
(4) and (3) taking 2000 g of sesame oil, refining into 1150 g, adding 100 g of beeswax and 50 g of borneol to obtain a mixed solution B, uniformly stirring, adding the concentrated solution B, fully and uniformly stirring, and cooling to room temperature to obtain the antibacterial preparation.
Preferably, the crude drugs are decocted in purified water in the step (3) with stirring for 1min every 15 min.
Example 3
A preparation for removing putrefaction and promoting granulation for scald and burn comprises the following components in parts by mass: 90-110 parts of giant knotweed, 90-110 parts of honeysuckle, 210 parts of asparagus 190-.
A preparation method of a preparation for removing putrefaction and promoting granulation for scald and burn comprises the following steps:
(1) after removing impurities and cleaning all the medicinal materials, weighing 100 g of giant knotweed, 100 g of honeysuckle, 200 g of asparagus, 100 g of coptis, 100 g of scutellaria and 100 g of phellodendron for later use according to the mixture ratio;
(2) pulverizing the raw materials into 50-100 mesh powder;
(3) mixing the pulverized medicinal materials, adding 2000ml of purified water, soaking for 45min, decocting for 65min in a stainless steel pot, filtering to obtain a first filtrate, adding 2000ml of purified water into the residue, decocting for 65min, filtering to obtain a second filtrate, mixing the two filtrates, and concentrating to 700ml to obtain a concentrated solution A;
(4) and (3) taking 2000 g of sesame oil, refining into 1150 g, adding 100 g of beeswax and 50 g of borneol to obtain a mixed solution B, uniformly stirring, adding the concentrated solution B, fully and uniformly stirring, and cooling to room temperature to obtain the antibacterial preparation.
Preferably, the crude drugs are decocted in purified water in the step (3) with stirring for 1min every 15 min.
The preparation is mainly used for treating: various lacerated wounds such as scalds, burns, skin decay and the like.
Precautions during application: the drug does not touch water, and is abstaining from spicy, seafood, wine, high-protein food and the like, and food with heavy pigment (such as soy sauce) is forbidden during the external application period.
The efficacy is as follows: the ointment has the advantages of quick pain relieving, inflammation diminishing, pus discharging, infection prevention, no hyperplasia, no fleshiness, gradual wound healing, no scar left after healing and obvious effect on treating hypertrophic scars.
The medication method comprises the following steps: the preparation is directly and uniformly applied to the burn and scald part without being cleaned by disinfectant liquid medicines, and the preparation is bound and fixed by gauze, and is replaced once in 6 to 8 hours. The effect is as follows: pain is relieved within 15 minutes, pus is discharged within about 2 days, the wound is closed up within about 5 days, the wound is repaired within about 10 days, the healing time of the wound is different according to the area, generally, a small area is scalded for about one week, and a large area is scalded for about 20 days.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.

Claims (5)

1. The preparation for removing putrefaction and promoting granulation for scalds and burns is characterized by comprising the following substances in parts by mass: 90-110 parts of giant knotweed, 90-110 parts of honeysuckle, 210 parts of asparagus 190-.
2. The preparation for removing the necrotic tissue and promoting tissue regeneration for scalds and burns according to claim 1, which is characterized by comprising the following components in parts by mass: 100 parts of giant knotweed, 100 parts of honeysuckle, 200 parts of asparagus, 100 parts of coptis, 100 parts of scutellaria, 100 parts of phellodendron, 2000 parts of sesame oil, 100 parts of beeswax and 50 parts of borneol.
3. The preparation method of the preparation for removing the necrotic tissue and promoting tissue regeneration for the scalds and the burns according to claim 1, which is characterized by comprising the following steps:
(1) after removing impurities and cleaning all the medicinal materials, weighing 100 g of giant knotweed, 100 g of honeysuckle, 200 g of asparagus, 100 g of coptis, 100 g of scutellaria and 100 g of phellodendron for later use according to the mixture ratio;
(2) pulverizing the raw materials into 50-200 mesh powder;
(3) mixing the pulverized medicinal materials, adding 2000ml of purified water, soaking for 25-45min, decocting for 55-65min in a stainless steel pot, filtering to obtain the first filtrate, adding 2000ml of purified water into the residue, decocting for 55-65min, filtering to obtain the second filtrate, mixing the two filtrates, and concentrating to 700ml to obtain concentrated solution A;
(4) and (3) taking 2000 g of sesame oil, refining into 1150 g, adding 100 g of beeswax and 50 g of borneol to obtain a mixed solution B, uniformly stirring, adding the concentrated solution B, fully and uniformly stirring, and cooling to room temperature to obtain the antibacterial preparation.
4. The preparation method of the preparation for removing putrefaction and promoting granulation of scald and burn as claimed in claim 3, wherein the preparation comprises: in the step (2), the medicinal materials are crushed into powder with 50-100 meshes.
5. The preparation method of the preparation for removing putrefaction and promoting granulation of scald and burn as claimed in claim 3, wherein the preparation comprises: and (4) decocting the medicinal materials with purified water in the step (3), and stirring for 1min every 15 min.
CN201911250775.3A 2019-12-09 2019-12-09 Preparation for removing putrefaction and promoting granulation of scald and burn and preparation method thereof Pending CN110693997A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108635399A (en) * 2018-08-02 2018-10-12 董云千 A kind of ointment for treating scald and its preparation method and application
CN112656839A (en) * 2020-12-31 2021-04-16 茂名市人民医院 Burn plaster
CN114848732A (en) * 2022-06-17 2022-08-05 湖南谷药齐全生物科技有限公司 External use liquid of grain medicine for treating inflammation and pain

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CN108686027A (en) * 2018-08-03 2018-10-23 邓怀展 The antibacterial ointment of scalds and burns putrefaction-removing granulation-promoting and preparation method

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108635399A (en) * 2018-08-02 2018-10-12 董云千 A kind of ointment for treating scald and its preparation method and application
CN112656839A (en) * 2020-12-31 2021-04-16 茂名市人民医院 Burn plaster
CN114848732A (en) * 2022-06-17 2022-08-05 湖南谷药齐全生物科技有限公司 External use liquid of grain medicine for treating inflammation and pain

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Application publication date: 20200117