CN110691787A - 针对家禽坏死性肠炎的疫苗 - Google Patents

针对家禽坏死性肠炎的疫苗 Download PDF

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Publication number
CN110691787A
CN110691787A CN201880036012.6A CN201880036012A CN110691787A CN 110691787 A CN110691787 A CN 110691787A CN 201880036012 A CN201880036012 A CN 201880036012A CN 110691787 A CN110691787 A CN 110691787A
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CN
China
Prior art keywords
polypeptide
lys
pilus
asn
seq
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Pending
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CN201880036012.6A
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English (en)
Chinese (zh)
Inventor
龚建华
D·莱普
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Agriculture and Agri-Food Canada
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Agriculture and Agri-Food Canada
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Publication of CN110691787A publication Critical patent/CN110691787A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/08—Clostridium, e.g. Clostridium tetani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1282—Clostridium (G)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/33—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Clostridium (G)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN201880036012.6A 2017-05-31 2018-05-31 针对家禽坏死性肠炎的疫苗 Pending CN110691787A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762513001P 2017-05-31 2017-05-31
US62/513,001 2017-05-31
PCT/CA2018/050643 WO2018218360A1 (en) 2017-05-31 2018-05-31 Vaccine against necrotic enteritis in poultry

Publications (1)

Publication Number Publication Date
CN110691787A true CN110691787A (zh) 2020-01-14

Family

ID=64454163

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201880036012.6A Pending CN110691787A (zh) 2017-05-31 2018-05-31 针对家禽坏死性肠炎的疫苗

Country Status (8)

Country Link
US (2) US11318194B2 (enExample)
EP (1) EP3630800A4 (enExample)
JP (2) JP2020527051A (enExample)
CN (1) CN110691787A (enExample)
BR (1) BR112019025019A2 (enExample)
CA (1) CA3064461A1 (enExample)
MX (1) MX2019014450A (enExample)
WO (1) WO2018218360A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113234130A (zh) * 2021-05-24 2021-08-10 安徽医科大学第四附属医院 一种卡氏肺孢子菌重组蛋白及其制备方法与应用

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025199604A1 (en) * 2024-03-27 2025-10-02 Université de Montréal Recombinant vaccine proteins for the prevention of avian necrotic enteritis
CN121759384B (zh) * 2026-03-05 2026-06-19 吉林农业大学 一种靶向树突状细胞的表达产气荚膜梭菌多抗原的重组乳杆菌及其构建方法与应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101198352A (zh) * 2005-04-18 2008-06-11 谢尔英·普劳有限公司 产气荚膜梭菌α类毒素疫苗
WO2008146164A2 (en) * 2007-05-25 2008-12-04 Novartis Ag Streptococcus pneumoniae pilus antigens
CN101578109A (zh) * 2006-10-27 2009-11-11 陶氏益农公司 用于坏死性肠炎的、包含突变的产气荚膜梭菌α毒素抗原的家禽疫苗及生产疫苗的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3614866B2 (ja) * 1997-06-12 2005-01-26 リサーチ コーポレイション テクノロジーズ，インコーポレイティド 人工抗体ポリペプチド
HK1045713A1 (zh) * 1999-07-13 2002-12-06 Medimmune, Inc. 供体链补体的菌毛蛋白和粘附素宽基疫苗
WO2007116322A2 (en) * 2006-02-17 2007-10-18 Novartis Ag Purification of bacterial antigens
EP2086578B1 (en) * 2006-11-20 2012-01-11 Intervet International B.V. Use of clostridium perfringens type c bacterium for the manufacture of a vaccine
MX2009012924A (es) * 2007-06-08 2010-03-25 Australian Poultry Crc Pty Ltd Toxina clostridial netb.
US8501190B2 (en) * 2007-06-22 2013-08-06 The University Of Guelph Vaccine against Clostridium perfringens
WO2011113801A1 (en) * 2010-03-16 2011-09-22 Universiteit Gent Use of clostridium perfringens strain 23 to protect against necrotic enteritis
AR099470A1 (es) * 2014-02-17 2016-07-27 Intervet Int Bv Vacunas de virus de aves de corral líquidas
FR3065623B1 (fr) * 2017-04-28 2021-07-09 Roquette Freres Albumines de pois ameliorees, procede d'obtention et leurs applications
BR112021000100A2 (pt) * 2018-07-05 2021-03-30 Novobind Livestock Therapeutics Inc. Anticorpos contra agentes causadores de doença de aves domésticas e usos dos mesmos

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101198352A (zh) * 2005-04-18 2008-06-11 谢尔英·普劳有限公司 产气荚膜梭菌α类毒素疫苗
CN101578109A (zh) * 2006-10-27 2009-11-11 陶氏益农公司 用于坏死性肠炎的、包含突变的产气荚膜梭菌α毒素抗原的家禽疫苗及生产疫苗的方法
WO2008146164A2 (en) * 2007-05-25 2008-12-04 Novartis Ag Streptococcus pneumoniae pilus antigens

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GENBANK: "hypothetical protein BXT94_03025 [Clostridium perfringens]" *
GENBANK: "hypothetical protein BXT94_03035 [Clostridium perfringens]" *
GENBANK: "putative collagen adhesin [Clostridium perfringens]" *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113234130A (zh) * 2021-05-24 2021-08-10 安徽医科大学第四附属医院 一种卡氏肺孢子菌重组蛋白及其制备方法与应用

Also Published As

Publication number Publication date
WO2018218360A1 (en) 2018-12-06
US11318194B2 (en) 2022-05-03
RU2019137515A (ru) 2021-06-30
JP2020527051A (ja) 2020-09-03
RU2019137515A3 (enExample) 2021-12-03
JP2023090702A (ja) 2023-06-29
MX2019014450A (es) 2020-02-10
BR112019025019A2 (pt) 2020-06-30
US20220226455A1 (en) 2022-07-21
CA3064461A1 (en) 2018-12-06
EP3630800A1 (en) 2020-04-08
US20200093913A1 (en) 2020-03-26
EP3630800A4 (en) 2021-03-24

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