CN110638926A

CN110638926A - Lung moistening and cough relieving substitutional tea and preparation process thereof

Info

Publication number: CN110638926A
Application number: CN201910918866.3A
Authority: CN
Inventors: 王明谦; 纪东艺
Original assignee: Ningbo Dekang Biological Products Co Ltd
Current assignee: Ningbo Dekang Biological Products Co Ltd
Priority date: 2019-09-26
Filing date: 2019-09-26
Publication date: 2020-01-03

Abstract

The invention belongs to the technical field of medicinal and edible traditional Chinese medicinal materials, and particularly relates to a substituted tea with a lung moistening and cough relieving function and a preparation process thereof. The substitute tea takes lily, platycodon grandiflorum, momordica grosvenori and honeysuckle as main raw materials, and can rapidly relieve symptoms of chest distress, cough and excessive phlegm of patients through synergistic effect. The preparation method adopts water boiling and adsorption, which not only improves the utilization rate of effective components, but also improves the taste, prolongs the drinking time and increases the brewing times. The tea substitute provided by the invention has the advantages that the body is nourished from the inside and the outside, the purpose of treating diseases and seeking the basis is realized, the carrying is facilitated, the drinking is convenient, and no contraindication is caused.

Description

Lung moistening and cough relieving substitutional tea and preparation process thereof

Technical Field

The invention belongs to the technical field of medicinal and edible traditional Chinese medicinal materials, and particularly relates to a substituted tea with a lung moistening and cough relieving function and a preparation process thereof.

Background

The haze (PM2.5) mainly comprises sulfur dioxide, nitrogen oxide and inhalable particles, and the three are combined with the fog to enable the sky to become cloudy, heavy and dark instantly. The particle is a pollutant and is a carrier of toxic substances such as heavy metal, polycyclic aromatic hydrocarbon and the like. As the economic and social activities of high-density population inevitably discharge a large amount of fine particulate matters (PM2.5), once the discharge amount exceeds the atmospheric circulation capacity and the bearing capacity, the concentration of the fine particulate matters is continuously accumulated, and at the moment, if the influence of quiet weather and the like is caused, the haze in a large range is extremely easy to appear.

As the diameter of fine powder-particle floating particles in haze is generally below 0.01 micron, the fine powder-particle floating particles can directly enter bronchus and even lung through a respiratory system, the haze influences the respiratory system of a person to the maximum extent, and diseases caused by the haze are mainly concentrated on respiratory diseases, cerebrovascular diseases, nasal inflammation and other disease categories. Meanwhile, in the dust-haze weather, the air pressure is reduced, the inhalable particles in the air are suddenly increased, the air flowability is poor, the speed of spreading harmful bacteria and viruses to the surroundings is slowed, the virus concentration in the air is increased, and the risk of disease transmission is high.

Air is a necessary condition for human survival, and for sustainable development and health needs, people are trying to reduce the emission of pollutants into the atmosphere, such as designing air purifier devices and protective articles to reduce the harm of pollutants to the body, but for the areas with severe haze, the attack and the stiffness are long-term, people inevitably need to go out for work and life, even if the protective articles are carefully worn, the protective effect is still very slight, and when the haze is in a severe sudden period, a large number of people can inhale harmful particles to cause respiratory tract and lung diseases, therefore, in order to relieve the threat of haze to human health, a substitute tea which takes medicinal and edible traditional Chinese medicinal materials as raw materials, is convenient to carry and drink and has the functions of protecting pharynx and lung is needed to meet the actual demand.

Disclosure of Invention

The invention aims to solve the problems in the prior art, and provides the substitutive tea taking medicinal and edible traditional Chinese medicinal materials as raw materials, which has the advantages of economic and easily available raw materials, simple preparation process, convenience for carrying and drinking, no contraindication for taking and good lung moistening and cough relieving effects.

The purpose of the invention can be realized by the following technical scheme: the substituted tea for moistening lung and relieving cough comprises the following raw material components in percentage by weight: 40-50% of lily, 10-30% of platycodon grandiflorum, 2-10% of chrysanthemum, 2-8% of liquorice, 10-30% of momordica grosvenori and 15-25% of honeysuckle.

Preferably, the lung moistening and cough relieving substitutional tea comprises the following raw material components in percentage by weight: 42-50% of lily, 10-20% of platycodon grandiflorum, 2-5% of chrysanthemum, 3-6% of liquorice, 12-24% of momordica grosvenori and 16-23% of honeysuckle.

According to the compendium of materia medica and the record of the pharmacopoeia of traditional Chinese medicine, the substitute tea of the invention has the following functional effects:

lily: bulbus Lilii is sweet in taste and cold in nature, enters heart and lung channels, has effects of nourishing yin and moistening lung, clearing heart fire and tranquilizing mind, and can be used for treating yin deficiency dry cough, cough with fatigue and hemoptysis.

Balloon flower: radix Platycodi is bitter and pungent in flavor, neutral in nature, has effects of dispersing lung qi, relieving sore throat, eliminating phlegm, and expelling pus when entering lung meridian, and is mainly used for treating cough with excessive phlegm, chest distress, pharyngalgia, hoarseness, lung carbuncle, and purulence.

Chrysanthemum: chrysanthemum flower, pungent, sweet, bitter and slightly cold, enters lung and liver meridians. Has the effects of dispelling wind and heat, calming liver, improving eyesight, and clearing away heat and toxic materials.

Licorice root: licorice root, radix Glycyrrhizae is a good product for clearing away heart-fire, nourishing blood, promoting the production of body fluid, moistening lung, clearing away heat and toxic material, purging pathogenic fire, moistening throat, nourishing kidney and tonifying yin, and has the main function of harmonizing the medicinal taste and properties of various medicines.

Momordica grosvenori: sweet taste and cool nature, enters lung and large intestine channels, has the effects of clearing heat, moistening lung, relieving sore throat and producing voice, and is commonly used for lung heat dry cough, pharyngalgia and aphonia.

Honeysuckle flower: sweet and cold in flavor, entering lung and stomach channels, can clear away heat and toxic material, disperse wind and heat, diminish inflammation and relieve swelling, is mainly used for treating exogenous wind and heat or warm disease fever, and has certain effects on toxic heat and bloody dysentery, carbuncle swelling and furuncle, dry throat and mouth, pharyngitis and the like.

According to traditional Chinese medicine, the pharyngitis is mostly caused by carelessness in daily life and failure of the lung and stomach, and invasion of wind-heat or wind-cold evil, which internally corresponds to the lung. The lung governs skin and hair to govern respiration, while lung deficiency is mostly manifested as cough, expectoration, dry mouth and throat, hoarseness, etc., all of the above herbs enter lung meridian, supplement each other, can quickly and effectively alleviate symptoms, and simultaneously regulate balance of internal organs of body from interior to achieve the purpose of treating fundamental disease.

The effective components of the main raw materials of lily, platycodon grandiflorum and momordica grosvenori have the effects of nourishing yin, moistening lung, reducing phlegm, relieving cough, relieving sore throat and producing voice, and the three components can cooperate to quickly relieve the symptoms of a patient; the honeysuckle is used as one of the main raw materials, is matched with the lily, the platycodon grandiflorum and the momordica grosvenori for use, and is beneficial to strengthening the drug property and preventing the secondary invasion of germs.

The invention also aims to provide a preparation process of the lung-moistening and cough-relieving substitutional tea, which specifically comprises the following steps:

(1) weighing the raw material components of the substitutional tea by weight percent: 40-50% of lily, 10-30% of platycodon grandiflorum, 2-10% of chrysanthemum, 2-8% of liquorice, 10-30% of momordica grosvenori and 15-25% of honeysuckle; then crushing and sieving the raw materials for later use;

(2) drying the chrysanthemum, the momordica grosvenori, the honeysuckle, 1/2-2/3 of lily and 1/2-2/3 of platycodon grandiflorum in the step (1) in an oven;

(3) mixing the rest lily and platycodon grandiflorum in the step (1), adding water, heating and extracting, adsorbing the extracting solution by liquorice, drying the adsorbed mixture, and sieving;

(4) and (3) mixing the dried raw materials in the step (2) with the adsorption mixture in the step (3), sterilizing and packaging to obtain the finished product of the substitutive tea.

The packaged dose of the substitutional tea of the invention comprises but is not limited to 1 g/bag, 3 g/bag, 5 g/bag and 6 g/bag. The dosage can be increased or decreased according to body constitution and individual symptoms.

The drinking method of the substitutional tea of the invention comprises the following steps: each bag is brewed with about 300mL of boiled water for 3-5 minutes and can be drunk.

Compared with the prior art that all the raw materials are mixed at one time to prepare the traditional Chinese medicine product for moistening the lung and relieving the cough, the invention carries out mixing, water boiling and adsorption with steps according to the attributes and the physicochemical properties of the components of the raw materials. The effective components of the lily and the platycodon root boiled in the water can be dissolved out by brewing the chrysanthemum, the momordica grosvenori and the honeysuckle in the water without special treatment, the lily and the platycodon root are raw materials of rhizomes and fruits, the texture is compact, the effective components are not easy to dissociate, so most of the effective components are boiled out by boiling the water, the liquorice is loose in texture and has a large amount of fibers, the effective components of the lily and the platycodon root boiled in the water can be almost completely adsorbed on the surface, the effective components of the lily and the platycodon root can be used as carriers of the effective components of the lily and the platycodon root while the effects of the other drugs are blended, and the adsorbed effective components of the lily and the platyc.

In addition, in the preparation process, part of lily and platycodon grandiflorum are boiled in water, so that the brewed tea water is appropriate in concentration and comfortable in taste, the effective components can be continuously brewed from the raw materials, and the service life is prolonged. 2 g/bag of the substitute tea product obtained by the preparation process can be brewed for 3-4 times repeatedly.

Preferably, the aperture of each raw material crushing and screening hole in the step (1) is 10-40 meshes.

Preferably, the drying temperature in the step (2) is 50-70 ℃, and the drying time is 30-60 min. The drying under the condition can not damage the effective components in the raw materials due to overhigh temperature, and can not cause the raw materials to be bonded due to overhigh temperature.

Preferably, the water adding amount in the step (3) is 1-4 times of the total amount of the remaining lily and platycodon grandiflorum. The proportion range is convenient for obtaining the extracting solution with moderate concentration, and is beneficial to the absorption of the effective components by the liquorice.

Preferably, the heating and extracting process in the step (3) comprises the following steps: mixing the raw materials, adding water, heating to 100 ℃ to boil, keeping slight boiling for 20-40 min, and extracting for 1-2 h. Under the condition, the active ingredients in the raw materials are maximally dissolved in the water.

Preferably, the sieve aperture of the adsorption mixture in the step (3) is 10-40 meshes. After the raw materials are boiled, the raw materials are easily stuck together after being dried again, and the grains are too large to be beneficial to the mixing of the raw materials and the dissolution of effective components, so that the raw materials need to be sieved again by a sieve with 10-40 meshes.

Compared with the prior art, the invention has the beneficial effects that:

1. the lily and platycodon root health-care tea has reasonable raw material compatibility, the lily, the platycodon root, the momordica grosvenori and the honeysuckle are used as main raw materials, the lily, the platycodon root and the momordica grosvenori have the effects of nourishing yin, moistening lung, eliminating phlegm, relieving cough, relieving sore throat and making sound in a synergistic mode, the symptoms of a patient can be rapidly relieved, and the honeysuckle is used in a matched mode, so that the drug property can.

2. According to the preparation process, a mode of combining water boiling and adsorption of partial raw materials is adopted, the effective components in the lily and the platycodon grandiflorum which are compact in texture and difficult to dissociate are dissolved out through water boiling, then the liquorice which is loose in texture and rich in a large number of fibers is used as an adsorption carrier, the dissolved effective components are fully adsorbed on the surface, and the adsorbed effective components can be dissolved out again after being brewed for 3-5 minutes during drinking, so that the utilization rate of the effective components is improved, the mouthfeel is improved, the drinking time is prolonged, and the brewing times are increased.

3. The invention takes medicinal and edible traditional Chinese medicinal materials as raw materials, the raw materials supplement each other, the body is nursed from inside to outside while the clinical symptoms of chest distress, unsmooth chest distress, cough and excessive phlegm are quickly and effectively relieved, the aim of treating the disease and seeking the basis is realized, and the invention is convenient to carry and drink and has no contraindication for taking.

Detailed Description

The following are specific examples of the present invention and illustrate the technical solutions of the present invention for further description, but the present invention is not limited to these examples. The raw materials used in the examples of the present invention are those commonly used in the art, and the methods used in the examples are those conventional in the art, unless otherwise specified.

Example 1

Weighing 40g of lily, 10g of platycodon grandiflorum, 7g of chrysanthemum, 8g of liquorice, 10g of momordica grosvenori and 25g of honeysuckle; then crushing the raw materials and sieving the crushed raw materials with a 10-mesh sieve for later use;

drying 7g of chrysanthemum, 10g of momordica grosvenori, 25g of honeysuckle, 20g of lily and 5g of platycodon grandiflorum in an oven at 50 ℃ for 30 min;

mixing the rest 20g of Bulbus Lilii and 5g of radix Platycodi, adding 25g of water, heating to 100 deg.C to boil, keeping slightly boiling for 20min, extracting for 1h, adsorbing the extractive solution with Glycyrrhrizae radix, drying the adsorption mixture at 55 deg.C for 120min, and sieving with 10 mesh sieve;

mixing the dried raw materials with the adsorption mixture, sterilizing, and packaging into 2 g/bag to obtain the final product of the substitutional tea.

Example 2

Weighing 45g of lily, 15g of platycodon grandiflorum, 3g of chrysanthemum, 4g of liquorice, 15g of momordica grosvenori and 18g of honeysuckle; then crushing the raw materials and sieving the crushed raw materials with a 15-mesh sieve for later use;

drying 3g of chrysanthemum, 15g of momordica grosvenori, 18g of honeysuckle, 25g of lily and 9g of platycodon grandiflorum in an oven at 55 ℃ for 40 min;

mixing the rest 20g of Bulbus Lilii and 6g of radix Platycodi, adding 50g of water, heating to 100 deg.C to boil, keeping slightly boiling for 25min, extracting for 1.5h, adsorbing the extractive solution with 4g of Glycyrrhrizae radix, drying the adsorbed mixture at 55 deg.C for 120min, and sieving with 15 mesh sieve;

mixing the dried raw materials with the adsorption mixture, sterilizing, and packaging to obtain the final product of the substitutional tea.

Example 3

Weighing 45g of lily, 15g of platycodon grandiflorum, 3g of chrysanthemum, 4g of liquorice, 15g of momordica grosvenori and 18g of honeysuckle; then crushing the raw materials and sieving the crushed raw materials with a 20-mesh sieve for later use;

drying 3g of chrysanthemum, 15g of momordica grosvenori, 18g of honeysuckle, 25g of lily and 9g of platycodon grandiflorum in an oven at 60 ℃ for 50 min;

mixing the rest 20g of Bulbus Lilii and 6g of radix Platycodi, adding 60g of water, heating to 100 deg.C to boil, keeping slightly boiling for 30min, extracting for 1.5h, adsorbing the extractive solution with 4g of Glycyrrhrizae radix, drying the adsorbed mixture at 55 deg.C for 120min, and sieving with 20 mesh sieve;

Example 4

Weighing 44g of lily, 14g of platycodon grandiflorum, 8g of chrysanthemum, 6g of liquorice, 12g of momordica grosvenori and 16g of honeysuckle; then crushing the raw materials, sieving by a 20-mesh sieve for later use;

drying 8g of chrysanthemum, 12g of momordica grosvenori, 16g of honeysuckle, 23g of lily and 8g of platycodon grandiflorum in an oven at 60 ℃ for 50 min;

mixing the rest 21g of Bulbus Lilii and 6g of radix Platycodi, adding 60g of water, heating to 100 deg.C to boil, keeping slightly boiling for 30min, extracting for 1.5h, adsorbing the extractive solution with 4g of Glycyrrhrizae radix, drying the adsorbed mixture at 55 deg.C for 120min, and sieving with 20 mesh sieve;

Example 5

Weighing 42g of lily, 15g of platycodon grandiflorum, 3g of chrysanthemum, 3g of liquorice, 20g of momordica grosvenori and 19g of honeysuckle; then crushing the raw materials and sieving the crushed raw materials with a 40-mesh sieve for later use;

drying 3g of chrysanthemum, 20g of momordica grosvenori, 19g of honeysuckle, 28g of lily and 10g of platycodon grandiflorum in an oven at 70 ℃ for 60 min;

mixing the rest 14g Bulbus Lilii and 5g radix Platycodi, adding 76g water, heating to 100 deg.C to boil, keeping slightly boiling for 40min, extracting for 2h, adsorbing the extractive solution with Glycyrrhrizae radix, drying the adsorption mixture at 55 deg.C for 120min, and sieving with 40 mesh sieve;

Comparative example 1

The raw material of comparative example 1 is only lily 100g, which is crushed and sieved by a 20-mesh sieve and then dried in an oven at 60 ℃ for 50 min; sterilizing, and packaging into 2 g/bag to obtain the substitute tea finished product.

Comparative example 2

The raw material of comparative example 2 is only 100g of platycodon grandiflorum, which is crushed and sieved by a 20-mesh sieve and then dried in an oven at 60 ℃ for 50 min; sterilizing, and packaging into 2 g/bag to obtain the substitute tea finished product.

Comparative example 3

The raw material of comparative example 3 is only 100g of momordica grosvenori, which is crushed and sieved by a 20-mesh sieve and then dried in an oven at 60 ℃ for 50 min; sterilizing, and packaging into 2 g/bag to obtain the substitute tea finished product.

Comparative example 4

The raw material of comparative example 4 is only 100g of honeysuckle, which is crushed and sieved by a 20-mesh sieve and then dried in an oven at 60 ℃ for 50 min; sterilizing, and packaging into 2 g/bag to obtain the substitute tea finished product.

Comparative example 5

The comparative example is different from example 3 only in that the preparation process does not adopt the steps of water boiling and adsorption, but the raw materials are directly dried in an oven at 60 ℃ for 50min, then are mixed, sterilized and packaged by 2 g/bag.

Application embodiment 1

1. Target selection: 400 people with chest distress, cough and excessive phlegm caused by environmental factors are selected in the cities with serious haze, such as Beijing, Tianjin and the like, wherein the patients are treated within 1 month, within 1-6 months, within 6-12 months and more than 1 year.

2. The treatment method comprises the following steps: after the substitutional tea of the embodiment 3 of the invention is taken, each bag is brewed with about 300mL of boiled water for 3-5 minutes, and the tea can be drunk, and each bag can be repeatedly brewed for 3-4 times, and one bag is taken every day.

3. The therapeutic effect judgment standard is as follows: the effect is shown: the symptoms of chest distress and cough basically disappear, and discomfort does not exist; the method has the following advantages: the chest distress is slowed down, the cough sputum is reduced, and the discomfort is relieved; and (4) invalidation: the discomfort of chest distress and cough is not relieved, and the symptoms are not improved. The observation period is 7 days, and if the effect is shown within 7 days, the administration is stopped; if the symptoms did not improve after 7 days, it was judged to be ineffective.

4. Therapeutic effects

The effective rate of the tea substitute for the tea in patients with chest distress, cough and excessive phlegm caused by the environment can reach more than 95%, and more than 6 patients can obviously feel more comfortable after brewing 1-2 bags. The therapeutic effect is shown in table 1.

Table 1: example 2 therapeutic Effect of tea substitute of the present invention

Application embodiment 2

1. Test materials and sources

Test materials: SD female healthy rats weighing 160-220 g;

the source is as follows: ningbo university center for laboratory animals

2. Test method

80 rats were divided into 8 groups of 10 rats by weight. The specific test method is as follows:

randomly extracting 7 groups from 8 groups of rats, raising the rats in a simulated PM2.5 environment for two weeks, and taking 1 group which is not raised in the PM2.5 environment as a blank group to take physiological saline; then randomly extracting 5 groups of the rats raised in 7 groups of PM2.5 environments, and respectively taking the substituted tea in comparative examples 1-5 of the invention; then, 1 group of the remaining 2 groups was randomly selected to take the substitutional tea of example 3 of the present invention, and the other 1 group was taken as a control group to take physiological saline. For convenience, 8 groups of rats are labeled 1-8#, respectively.

The tea water with the same concentration is prepared from the substituted tea in comparative examples 1-5 and the physiological saline in example 3 and the physiological saline of a blank group and a control group, and the substituted tea and the physiological saline are respectively administrated to 1-8# rats 6 times a day by respectively administrating 2ml each time to the rats by gavage, wherein the substituted tea in comparative examples 1-5 is respectively administrated to 1-5# rats, the substituted tea in example 3 is administrated to 6# rats, and the physiological saline is respectively administrated to 7# control rats and 8# blank group rats.

3. Evaluation of results

After being raised for two weeks in a PM2.5 simulating environment, rats are fed with dysphoria and cachexia in mental states; the glossiness of the hair color is obviously reduced, and the hair removal phenomenon is caused; the activity is obviously reduced, and most of the activity stays in corners; the average water intake was 39.52.

The administration was continued for four weeks, and the mental state, hair color, activity and water intake of the rats were observed. The change of the state of the rats after taking the tea water with different components is shown in the table 2.

Table 2: test of State Change in rats after administration of different tea Water

As is apparent from the physical condition of rats, the effect of improving the symptoms of the rats is not obvious when 1-4# takes the single raw material components in comparative examples 1-4 or 5# takes the substituted tea of comparative example 5 without water boiling and adsorption steps. The substituted tea prepared by the raw materials and the process of the embodiment 3 of the invention obviously improves the appearance symptoms of rats. The different results reflect the interaction of the active ingredients of the raw materials and the substitutional tea obtained by the preparation process, and the active ingredients are easy to separate out, so that the symptoms can be quickly relieved after drinking, and the pain of patients can be solved.

The technical scope of the invention claimed by the embodiments herein is not exhaustive and new solutions formed by equivalent replacement of single or multiple technical features in the embodiments are also within the scope of the invention, and all parameters involved in the solutions of the invention do not have mutually exclusive combinations if not specifically stated.

The specific embodiments described herein are merely illustrative of the spirit of the invention. Various modifications or additions may be made to the described embodiments or alternatives may be employed by those skilled in the art without departing from the spirit or ambit of the invention as defined in the appended claims.

Claims

1. The lung moistening and cough relieving substitutional tea is characterized by comprising the following raw material components in percentage by weight: 40-50% of lily, 10-30% of platycodon grandiflorum, 2-10% of chrysanthemum, 2-8% of liquorice, 10-30% of momordica grosvenori and 15-25% of honeysuckle.

2. The lung moistening and cough arresting substitutional tea according to claim 1, which is characterized by comprising the following raw material components in percentage by weight: 42-50% of lily, 10-20% of platycodon grandiflorum, 2-5% of chrysanthemum, 3-6% of liquorice, 12-24% of momordica grosvenori and 16-23% of honeysuckle.

3. The preparation process of the lung moistening and cough arresting substitutional tea as claimed in claim 1, wherein the preparation process comprises the following steps:

(1) weighing the raw material components of the substitutional tea according to the weight percentage in the claim 1: 40-50% of lily, 10-30% of platycodon grandiflorum, 2-10% of chrysanthemum, 2-8% of liquorice, 10-30% of momordica grosvenori and 15-25% of honeysuckle; then crushing and sieving the raw materials for later use;

(3) mixing the rest lily and platycodon grandiflorum in the step (1), adding water, heating and extracting, adsorbing the extracting solution by liquorice, drying and sieving the adsorbed mixture;

4. The preparation process of the substituted tea for moistening lung to arrest cough according to claim 2, wherein the crushed raw materials in the step (1) have the mesh size of 10-40 meshes.

5. The preparation process of the substituted tea for moistening lung to arrest cough according to claim 2, wherein the drying temperature in the step (2) is 50-70 ℃, and the drying time is 30-60 min.

6. The preparation process of the substituted tea for moistening lung to arrest cough according to claim 2, wherein the water addition amount in the step (3) is 1-4 times of the total amount of the remaining lily and platycodon grandiflorum.

7. The preparation process of the substituted tea for moistening lung to arrest cough according to claim 2, wherein the heating and extracting process in the step (3) comprises the following specific steps: mixing the raw materials, adding water, heating to 100 ℃ to boil, keeping slight boiling for 20-40 min, and extracting for 1-2 h.

8. The preparation process of the substituted tea for moistening lung to arrest cough according to claim 2, wherein the adsorption mixture in the step (3) is sieved by a sieve with a pore size of 10-40 meshes.