CN105748884A - Drug or health food with effects of clearing lung and relieving sore throat - Google Patents

Drug or health food with effects of clearing lung and relieving sore throat Download PDF

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Publication number
CN105748884A
CN105748884A CN201410787926.XA CN201410787926A CN105748884A CN 105748884 A CN105748884 A CN 105748884A CN 201410787926 A CN201410787926 A CN 201410787926A CN 105748884 A CN105748884 A CN 105748884A
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China
Prior art keywords
lung
health food
medicine
fructus momordicae
flos lonicerae
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CN201410787926.XA
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Chinese (zh)
Inventor
况代武
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Yantai Baobei Biotechnology Co Ltd
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Yantai Baobei Biotechnology Co Ltd
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Priority to CN201410787926.XA priority Critical patent/CN105748884A/en
Publication of CN105748884A publication Critical patent/CN105748884A/en
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Abstract

The present invention relates to a drug or health food with effects of clearing lung and relieving sore throat, and the drug or health food with effects of clearing lung and relieving sore throat is characterized by containing effective ingredients of honeysuckle, scaphium scaphigerum, lily, fructus momordicae and platycodon grandiflorum. Pharmacological studies show that the drug or health food has good effects of clearing lung and relieving sore throat.

Description

The medicine of a kind of removing heat from the lung and relieving sorethroat or health food
Technical field
The present invention relates to a kind of medical material combination, be specifically related to a kind of medicine with removing heat from the lung and relieving sorethroat effect or health food.
Background technology
Society industrial development is rapid, while high speed development, has also caused the sharply deterioration of environment.The continuous deterioration of air quality, cause that haze weather often occurs, the coup injury respiratory system of people, the serious health endangering the mankind.How safely and effectively this just makes us in the face of an important problem: the respiratory system of conditioning, maintenance people, it is ensured that the health of health.
Summary of the invention
It is an object of the invention to provide the medicine of a kind of safely and effectively removing heat from the lung and relieving sorethroat or health food.
The medicine of removing heat from the lung and relieving sorethroat of the present invention or health food, mainly contain following functional component: Flos Lonicerae, Semen Sterculiae Lychnophorae, Bulbus Lilii, Fructus Momordicae and Radix Platycodonis.
Wherein, Flos Lonicerae is the flower just opened Caprifoliaceae woodbine Radix Ophiopogonis and congener dry flower or band.Sweet in the mouth, cold in nature, there is the effect of heat-clearing and toxic substances removing, dispelling wind and heat pathogens.Flos Lonicerae has heat-clearing and toxic substances removing, dredges the effect of throat, relieving restlessness of relieving summer heat.The diseases such as febrile disease due to summer-heat pathogen, dysentery, influenza, furuncle toxic swelling, acute and chronic tonsillitis, periodontitis can be treated.Modern study shows, the composition chlorogenic acid in Flos Lonicerae has antibacterial and antiviral, enhancing immunity and antiinflammatory, the effect such as antipyretic.
Semen Sterculiae Lychnophorae is the dry mature seed of Sterculiaceae plant Semen Sterculiae Lychnophorae.Chinese medicine is thought and is entered Semen Sterculiae Lychnophorae sweet in the mouth, cool in nature lung, large intestine channel, have effect of clearing away lung-heat, throat, removing toxic substances, loosening bowel to relieve constipation.For lung-heat celostomia, have sore throat, constipation with heat retention and with diseases such as the throat hoarseness caused such as excessive.
Bulbus Lilii, is Liliaceae lilium perennial herb bulbous plant.Chinese medicine thinks Bulbus Lilii sweet in the mouth, micro-hardship, and cold nature enters the heart, lung meridian, has nourishing YIN and moistening the lung;Effect of clearing away heart-fire for tranquillization.Cure mainly deficiency of YIN chronic cough;Sputum mixed with blood;The calentura later stage;Waste heat is unclear, or the unsuccessful caused fidgets due to deficiency palpitation with fear of feelings will, insomnia and dreamful sleep, absentminded;Carbuncle;The diseases such as eczema.The zoopery of modern medicine study shows, Bulbus Lilii has the effect of obvious relieving cough and expelling phlegm and calmness.
Fructus Momordicae, the dry fruit of the perennial liana Fructus Momordicae of Cucurbitaceae.Recording according to 2010 editions " Chinese Pharmacopoeia ", this product sweet in the mouth is cool in nature.Return lung, large intestine channel.There are clearing heat and moistening lung, relieving sore throat to recover voice, effect of loosening bowel to relieve constipation.It is mainly used in lung-heat type cough, pharyngalgia aphonia, dryness of the intestine constipation.Modern study shows, in Fructus Momordicae extract triterpene glucoside V have significantly eliminate the phlegm, cough-relieving, spasmolytic effect.
Radix Platycodonis, for the dry root of Campanulaceae Radix Platycodonis.This product bitter in the mouth, pungent, property is put down.Return lung meridian.Have lung qi dispersing, sore-throat relieving, eliminate the phlegm, effect of evacuation of pus.Too many for coughing, uncomfortable in chest not smooth, pharyngalgia hoarseness, lung abscess vomiting pus.Modern pharmacology experiments show that, multiple saponin separating obtained in Radix Platycodonis has obvious eliminating phlegm and relieving cough effect, additionally, also have the effect such as antiinflammatory, blood sugar lowering concurrently.
The present invention selects Flos Lonicerae heat-clearing and toxic substances removing, Semen Sterculiae Lychnophorae removing heat from the lung and relieving sorethroat, Bulbus Lilii nourishing YIN and moistening the lung, Fructus Momordicae relieving sore throat to recover voice, and Radix Platycodonis lung qi dispersing eliminates the phlegm.All medicines share, and play depressed lung-energy dispersing altogether, the effect of relieving sore throat to recover voice.Fundamentally moistening lung and nourishing throat, alleviates the adverse circumstances damages to body such as haze.
The optimum extraction process of this medicine or health food:
Weigh the medical material of following weight proportion: Flos Lonicerae 6, Semen Sterculiae Lychnophorae 4, Bulbus Lilii 6, Fructus Momordicae 9, Radix Platycodonis 6, decoct 2 times, first time adds the soak by water 2 hours of 10 times amount, second time adds the soak by water 1 hour of 8 times amount, collecting decoction, filtering, it is the thick paste of 1.25 that extracting solution is concentrated into relative density when 50 DEG C.
This extract has good removing heat from the lung and relieving sorethroat effect.
Relevant pharmacological experimental data
1, animal subject
Healthy Kunming mouse, body weight 18 ~ 20 grams, male and female half and half.
2, administering mode
Matched group: normal saline gastric infusion, continuous 7 days;
Experimental group: optimum proportioning extract 1mL/10g gastric infusion of the present invention, continuous 7 days.
3, experimental technique and interpretation of result
3.1 antiinflammatory actions (impact of xylol induced mice ear swelling)
After last administration 1h, being coated with caused by dimethylbenzene xylene in every Mus auris dextra tow sides scorching, left ear compares, and is put to death, lay auricle, scales/electronic balance weighing at the two same positions of ear respectively with diameter 9mm card punch after causing scorching 30min.The auris dextra sheet weight of every Mus deducts left auricle weight, is swelling degree.
Table 1. antiinflammatory action (± SD)
P < 0.05, compared with matched group, the clear swelling degree of experimental mice significantly reduces, and antiinflammatory action is obvious.
3.2 resolve phlegm effects
After last administration 1h, lumbar injection phenol red solution (5mg/10g), cervical dislocation place after 30min
Dead animal, peels off trachea surrounding tissue, cuts from thyroid cartilage down to one section of trachea of trachea bifurcation, put in the test tube filling 2mL normal saline, add 0.1mLNaOH (1mol/L), survey OD value with 721 type spectrophotometers (wavelength 546m), relatively each group difference.
Table 2. resolve phlegm effect (± SD)
P < 0.05, compared with matched group, experimental mice is had obvious resolve phlegm effect by extract.
3.3 antitussive actions
After last administration 1h, mice is placed in inverted wide mouthed bottle, in bottle, places pre-prepd ammonia cotton balls (cotton balls includes ammonia 0.2mL), observe mouse cough latent time and cough number of times in 3min, respectively organize difference.
Table 3. antitussive action (± SD)
P < 0.05, compared with matched group, extract is obvious to experimental mice antitussive action.
Detailed description of the invention
Embodiment 1:
Weighing Flos Lonicerae 150g, Semen Sterculiae Lychnophorae 100g, Bulbus Lilii 150g, Fructus Momordicae 225g, Radix Platycodonis 150g, decoct 2 times, first time adds the soak by water 2 hours of 10 times amount, second time adds the soak by water 1 hour of 8 times amount, collecting decoction, filters, and it is the thick paste of 1.20 that extracting solution is concentrated into relative density when 50 DEG C.Adding dextrin 850g, stevioside 2g, granulate, 75 DEG C dry, and granulate is packaged into bag.
Embodiment 2:
Weigh the medical material of following weight proportion: Flos Lonicerae 6, Semen Sterculiae Lychnophorae 4, Bulbus Lilii 6, Fructus Momordicae 9, Radix Platycodonis 6, decoct 2 times, first time adds the soak by water 2 hours of 10 times amount, second time adds the soak by water 1 hour of 8 times amount, collecting decoction, filtering, it is the thick paste of 1.20 that extracting solution is concentrated into relative density when 50 DEG C.Add dextrin 8
Weight portion, stevioside 0.016 weight portion, granulate, and 75 DEG C dry, and granulate is packaged into bag.
Embodiment 3:
Weighing the medical material of following weight proportion: Flos Lonicerae 3, Semen Sterculiae Lychnophorae 2, Bulbus Lilii 3, Fructus Momordicae 4, Radix Platycodonis 1, add the soak by water 0.5 hour of 6 times amount, filter, it is the thick paste of 1.10 that extracting solution is concentrated into relative density when 50 DEG C, dry, pulverize, and loads capsule.
Embodiment 4:
Weigh the medical material of following weight proportion: Flos Lonicerae 3, Semen Sterculiae Lychnophorae 2, Bulbus Lilii 3, Fructus Momordicae 2, Radix Platycodonis 3, decoct 3 times, first time adds the soak by water 2 hours of 10 times amount, and second time adds the soak by water 1.5 hours of 8 times amount, and third time adds the soak by water 1 hour of 6 times amount, collecting decoction, filtering, it is the thick paste of 1.50 that extracting solution is concentrated into relative density when 50 DEG C, adds Polyethylene Glycol 20 weight portion, melted, make drop pill.

Claims (6)

1. a medicine with removing heat from the lung and relieving sorethroat function or health food, it is characterised in that containing active ingredient: Flos Lonicerae, Semen Sterculiae Lychnophorae, Bulbus Lilii, Fructus Momordicae, Radix Platycodonis.
2. the medicine with removing heat from the lung and relieving sorethroat function according to claim 1 or health food, it is characterised in that its weight proportion containing each effective ingredient is: Flos Lonicerae 1-30 part, Semen Sterculiae Lychnophorae 2-40 part, Bulbus Lilii 1-30 part, Fructus Momordicae 1-80 part, Radix Platycodonis 1-30 part.
3. the medicine with removing heat from the lung and relieving sorethroat function according to claim 2 or health food, it is characterised in that its weight proportion containing each effective ingredient is: Flos Lonicerae 6 parts, Semen Sterculiae Lychnophorae 4 parts, Bulbus Lilii 6 parts, Fructus Momordicae 9 parts, Radix Platycodonis 6 parts.
4. the medicine with removing heat from the lung and relieving sorethroat function according to Claims 2 or 3 or health food, it is characterised in that its preparation technology is: weighs the Flos Lonicerae of above-mentioned weight proportion, Semen Sterculiae Lychnophorae, Bulbus Lilii, Fructus Momordicae and Radix Platycodonis and adds 10 times amount soak by water 2 hours, filters;Filtering residue adds 8 times amount soak by water 1 hour again, collecting decoction, filters, and it is the thick paste of 1.20 that extracting solution is concentrated into relative density when 50 DEG C.
5. the medicine with removing heat from the lung and relieving sorethroat function according to Claims 2 or 3 or health food, it is characterized in that its preparation technology is: weigh the Flos Lonicerae of above-mentioned weight proportion, Semen Sterculiae Lychnophorae, Bulbus Lilii, Fructus Momordicae, Radix Platycodonis, add 10 times amount soak by water 2 hours, filter;Filtering residue adds 8 amount soak by water 1 hour, collecting decoction, filters, and it is the thick paste of 1.20 that extracting solution is concentrated into relative density when 50 DEG C.
6. adding dextrin 8 weight portion, stevioside 0.016 weight portion, granulate, 75 DEG C dry, and granulate makes granule.
CN201410787926.XA 2014-12-19 2014-12-19 Drug or health food with effects of clearing lung and relieving sore throat Pending CN105748884A (en)

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106511740A (en) * 2016-11-11 2017-03-22 吉林省盛世华鑫生物科技有限公司 Radix ginseng-containing health product and preparation method therefor
CN106723037A (en) * 2016-12-24 2017-05-31 山东建筑大学 The preparation method and products obtained therefrom of a kind of sterculia seed throat-clearing throat-moistening fermentation capsule
CN107897414A (en) * 2017-11-23 2018-04-13 上海诺德生物实业有限公司 A kind of clearing lung type tea of relieving cough and diminishing inflammation and its preparation and application
CN108308470A (en) * 2018-04-26 2018-07-24 江西中医药大学 Expelling phlegm and arresting coughing drink and its preparation method and application
CN108497137A (en) * 2018-04-23 2018-09-07 钱海燕 A kind of health protection tea with relieving sore-throat moistening lung
CN108782888A (en) * 2018-05-07 2018-11-13 合肥御和轩养生科技有限公司 A kind of clear haze moistening lung health preserving tea and its preparation process
CN109125597A (en) * 2018-08-27 2019-01-04 重庆市中药研究院 A kind of shaddock flesh buccal tablet and preparation method thereof
CN110638926A (en) * 2019-09-26 2020-01-03 宁波德康生物制品有限公司 Lung moistening and cough relieving substitutional tea and preparation process thereof
CN114190552A (en) * 2020-09-17 2022-03-18 湖南康润农业科技发展有限公司 Lily lozenge and its preparing method

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1569192A (en) * 2004-04-29 2005-01-26 吕文晓 Gorge caring tea and its preparing process
CN101095517A (en) * 2007-07-27 2008-01-02 王奉友 Health care food having a function of cleaning pharynx

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1569192A (en) * 2004-04-29 2005-01-26 吕文晓 Gorge caring tea and its preparing process
CN101095517A (en) * 2007-07-27 2008-01-02 王奉友 Health care food having a function of cleaning pharynx

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106511740A (en) * 2016-11-11 2017-03-22 吉林省盛世华鑫生物科技有限公司 Radix ginseng-containing health product and preparation method therefor
CN106511740B (en) * 2016-11-11 2019-07-26 吉林省盛世华鑫生物科技有限公司 A kind of product and preparation method thereof comprising ginseng
CN106723037A (en) * 2016-12-24 2017-05-31 山东建筑大学 The preparation method and products obtained therefrom of a kind of sterculia seed throat-clearing throat-moistening fermentation capsule
CN107897414A (en) * 2017-11-23 2018-04-13 上海诺德生物实业有限公司 A kind of clearing lung type tea of relieving cough and diminishing inflammation and its preparation and application
CN108497137A (en) * 2018-04-23 2018-09-07 钱海燕 A kind of health protection tea with relieving sore-throat moistening lung
CN108308470A (en) * 2018-04-26 2018-07-24 江西中医药大学 Expelling phlegm and arresting coughing drink and its preparation method and application
CN108308470B (en) * 2018-04-26 2021-10-08 江西中医药大学 Phlegm-eliminating cough-relieving beverage and preparation method and application thereof
CN108782888A (en) * 2018-05-07 2018-11-13 合肥御和轩养生科技有限公司 A kind of clear haze moistening lung health preserving tea and its preparation process
CN109125597A (en) * 2018-08-27 2019-01-04 重庆市中药研究院 A kind of shaddock flesh buccal tablet and preparation method thereof
CN109125597B (en) * 2018-08-27 2021-03-16 重庆市中药研究院 Shaddock pulp buccal tablet and preparation method thereof
CN110638926A (en) * 2019-09-26 2020-01-03 宁波德康生物制品有限公司 Lung moistening and cough relieving substitutional tea and preparation process thereof
CN114190552A (en) * 2020-09-17 2022-03-18 湖南康润农业科技发展有限公司 Lily lozenge and its preparing method

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