CN110621306A - 膜脂包被纳米颗粒及其使用方法 - Google Patents

膜脂包被纳米颗粒及其使用方法 Download PDF

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Publication number
CN110621306A
CN110621306A CN201880032047.2A CN201880032047A CN110621306A CN 110621306 A CN110621306 A CN 110621306A CN 201880032047 A CN201880032047 A CN 201880032047A CN 110621306 A CN110621306 A CN 110621306A
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virus
cell
nanoparticle
membrane
solution
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Chinese (zh)
Inventor
埃迪·约孔·钟
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Costa Treatment
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Costa Treatment
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Priority to CN202511365346.6A priority Critical patent/CN121154578A/zh
Publication of CN110621306A publication Critical patent/CN110621306A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5176—Compounds of unknown constitution, e.g. material from plants or animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
    • A61K9/5068—Cell membranes or bacterial membranes enclosing drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/761—Adenovirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5176—Compounds of unknown constitution, e.g. material from plants or animals
    • A61K9/5184—Virus capsids or envelopes enclosing drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10332—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Botany (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Microbiology (AREA)
  • Optics & Photonics (AREA)
  • Dermatology (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
CN201880032047.2A 2017-04-21 2018-04-21 膜脂包被纳米颗粒及其使用方法 Pending CN110621306A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202511365346.6A CN121154578A (zh) 2017-04-21 2018-04-21 膜脂包被纳米颗粒及其使用方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762488685P 2017-04-21 2017-04-21
US62/488,685 2017-04-21
PCT/US2018/028752 WO2018195526A1 (en) 2017-04-21 2018-04-21 Membrane lipid coated nanoparticles and method of use

Related Child Applications (1)

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CN202511365346.6A Division CN121154578A (zh) 2017-04-21 2018-04-21 膜脂包被纳米颗粒及其使用方法

Publications (1)

Publication Number Publication Date
CN110621306A true CN110621306A (zh) 2019-12-27

Family

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CN201880032047.2A Pending CN110621306A (zh) 2017-04-21 2018-04-21 膜脂包被纳米颗粒及其使用方法
CN202511365346.6A Pending CN121154578A (zh) 2017-04-21 2018-04-21 膜脂包被纳米颗粒及其使用方法

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Country Status (6)

Country Link
US (1) US11413252B2 (https=)
EP (1) EP3612169A4 (https=)
JP (1) JP7329839B2 (https=)
KR (1) KR102581296B1 (https=)
CN (2) CN110621306A (https=)
WO (1) WO2018195526A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115252582A (zh) * 2022-08-19 2022-11-01 复旦大学 红细胞膜杂合pH脂质体包被溶瘤病毒制剂的制备及应用
CN115768499A (zh) * 2020-01-20 2023-03-07 阿瑞萨生物科技有限责任公司 含有细胞膜的装置及其用途
CN117379389A (zh) * 2022-07-12 2024-01-12 四川大学 血小板-溶瘤病毒复合物、其制备方法及其应用

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* Cited by examiner, † Cited by third party
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AU2018316166A1 (en) 2017-08-07 2020-02-06 The Regents Of The University Of California Platform for generating safe cell therapeutics
AU2020315645A1 (en) 2019-07-16 2022-02-17 Coastar Therapeutics Inc. Process of making membrane lipid coated nanoparticles
CN110638784A (zh) * 2019-09-27 2020-01-03 兆科（广州）肿瘤药物有限公司 一种载有溶瘤病毒的载药微球及其制备方法
WO2023113550A1 (ko) * 2021-12-16 2023-06-22 주식회사 포투가바이오 수지상세포 모방 기능성 나노구조체 및 이의 제조방법

Citations (6)

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US20100203024A1 (en) * 2006-05-30 2010-08-12 Terman David S Sickled Erythrocytes, Nucleated Precursors & Erythroleukemia Cells for Targeted Delivery of Oncolytic Viruses, Anti-tumor Proteins, Plasmids, Toxins, Hemolysins & Chemotherapy
US20140335115A1 (en) * 2013-05-07 2014-11-13 Oregon Health & Science University Suppressors of mature t cells
WO2016010840A1 (en) * 2014-07-16 2016-01-21 Novartis Ag Method of encapsulating a nucleic acid in a lipid nanoparticle host
US20160067191A1 (en) * 2013-04-18 2016-03-10 The Regents Of The University Of California Nanoscale coatings for encapsulation of biological entities
US20160317591A1 (en) * 2013-03-13 2016-11-03 Karen S. Aboody Tropic cell based virotherapy for the treatment of cancer
WO2016205009A1 (en) * 2015-06-19 2016-12-22 The Regents Of The University Of California Treating infection by a platelet-targeting microbe using nanoparticles

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DE69517683T2 (de) * 1994-03-15 2001-06-07 Medical College Of Pennsylvania And Hahnemann University, Philadelphia Alpha-galactosyl-epitope enthaltende zusammensetzungen und verfahren für impfstoffe
IL159334A0 (en) 2001-06-25 2004-06-01 Yissum Res Dev Co A method for preparation of vesicles loaded with biological material and different uses thereof
WO2006090816A1 (ja) 2005-02-25 2006-08-31 Mie University リポソームワクチンの作製法
CN103857387B (zh) * 2011-06-02 2017-03-15 加利福尼亚大学董事会 膜包封的纳米颗粒及使用方法
US20140350087A9 (en) * 2012-03-22 2014-11-27 Halozyme, Inc. Oncovector Nucleic Acid Molecules and Methods of Use
US10113151B2 (en) 2012-10-29 2018-10-30 The Regents Of The University Of California Composition of viral vectors in lecithin liposomes, preparation method and treatment methods
CN104958324A (zh) 2015-05-29 2015-10-07 黄波 一种溶瘤病毒制剂及其制备方法

Patent Citations (6)

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Publication number Priority date Publication date Assignee Title
US20100203024A1 (en) * 2006-05-30 2010-08-12 Terman David S Sickled Erythrocytes, Nucleated Precursors & Erythroleukemia Cells for Targeted Delivery of Oncolytic Viruses, Anti-tumor Proteins, Plasmids, Toxins, Hemolysins & Chemotherapy
US20160317591A1 (en) * 2013-03-13 2016-11-03 Karen S. Aboody Tropic cell based virotherapy for the treatment of cancer
US20160067191A1 (en) * 2013-04-18 2016-03-10 The Regents Of The University Of California Nanoscale coatings for encapsulation of biological entities
US20140335115A1 (en) * 2013-05-07 2014-11-13 Oregon Health & Science University Suppressors of mature t cells
WO2016010840A1 (en) * 2014-07-16 2016-01-21 Novartis Ag Method of encapsulating a nucleic acid in a lipid nanoparticle host
WO2016205009A1 (en) * 2015-06-19 2016-12-22 The Regents Of The University Of California Treating infection by a platelet-targeting microbe using nanoparticles

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MATTHIAS: "Stem Cells Loaded With Multimechanistic Oncolytic Herpes", 《JNCI》 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115768499A (zh) * 2020-01-20 2023-03-07 阿瑞萨生物科技有限责任公司 含有细胞膜的装置及其用途
CN117379389A (zh) * 2022-07-12 2024-01-12 四川大学 血小板-溶瘤病毒复合物、其制备方法及其应用
CN115252582A (zh) * 2022-08-19 2022-11-01 复旦大学 红细胞膜杂合pH脂质体包被溶瘤病毒制剂的制备及应用
CN115252582B (zh) * 2022-08-19 2024-01-02 复旦大学 红细胞膜杂合pH脂质体包被溶瘤病毒制剂的制备及应用

Also Published As

Publication number Publication date
KR102581296B1 (ko) 2023-09-22
EP3612169A4 (en) 2020-09-09
JP2020519241A (ja) 2020-07-02
KR20190137906A (ko) 2019-12-11
US20200060979A1 (en) 2020-02-27
EP3612169A1 (en) 2020-02-26
WO2018195526A1 (en) 2018-10-25
JP7329839B2 (ja) 2023-08-21
US11413252B2 (en) 2022-08-16
CN121154578A (zh) 2025-12-19

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