CN110612106A - 伤口愈合药物 - Google Patents

伤口愈合药物 Download PDF

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Publication number
CN110612106A
CN110612106A CN201880028799.1A CN201880028799A CN110612106A CN 110612106 A CN110612106 A CN 110612106A CN 201880028799 A CN201880028799 A CN 201880028799A CN 110612106 A CN110612106 A CN 110612106A
Authority
CN
China
Prior art keywords
hydrogel
deoxyribose
use according
wound
carrier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201880028799.1A
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English (en)
Chinese (zh)
Inventor
M·亚尔
S·麦克尼尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Sheffield
Comsats Institute of Information Technology
Original Assignee
University of Sheffield
Comsats Institute of Information Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Sheffield, Comsats Institute of Information Technology filed Critical University of Sheffield
Publication of CN110612106A publication Critical patent/CN110612106A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/244—Lanthanides; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/38—Silver; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/731—Cellulose; Quaternized cellulose derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0052—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/008—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201880028799.1A 2017-03-07 2018-03-07 伤口愈合药物 Pending CN110612106A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1703656.7 2017-03-07
GBGB1703656.7A GB201703656D0 (en) 2017-03-07 2017-03-07 Wound healing medicament
PCT/GB2018/050579 WO2018162900A1 (en) 2017-03-07 2018-03-07 Wound healing medicament

Publications (1)

Publication Number Publication Date
CN110612106A true CN110612106A (zh) 2019-12-24

Family

ID=58543858

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201880028799.1A Pending CN110612106A (zh) 2017-03-07 2018-03-07 伤口愈合药物

Country Status (9)

Country Link
US (3) US20210154206A1 (enExample)
EP (2) EP3681509B1 (enExample)
JP (3) JP7710206B2 (enExample)
CN (1) CN110612106A (enExample)
CA (1) CA3055467A1 (enExample)
ES (1) ES2955029T3 (enExample)
GB (1) GB201703656D0 (enExample)
SG (1) SG11201908060PA (enExample)
WO (1) WO2018162900A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115770322A (zh) * 2022-11-29 2023-03-10 江南大学 一种免疫调节水凝胶及其制备方法和应用
CN115944774A (zh) * 2022-12-04 2023-04-11 吉林大学 一种迷迭香酸-壳聚糖-聚乙烯醇水凝胶敷料及其制备方法和应用

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9884027B2 (en) 2012-01-12 2018-02-06 Nanofiber Solutions, Inc. Nanofiber scaffolds for biological structures
GB201703656D0 (en) 2017-03-07 2017-04-19 Univ Sheffield Wound healing medicament
US12458538B2 (en) 2018-10-24 2025-11-04 Ambient Biosciences, Inc. Functional wound healing dressings
BR112021011361A2 (pt) 2018-12-11 2021-08-31 Nanofiber Solutions, Llc Método para tratar uma ferida crônica, método para afetar o ph inicial de uma porção de um corpo e método para reduzir o ph inicial de uma ferida crônica
CA3182868A1 (en) * 2020-07-22 2022-01-27 John K. Jackson Blended polyvinyl alcohol drug delivery systems
WO2022076117A1 (en) * 2020-09-08 2022-04-14 Protein Genomics Inc. Biomimetic wound healing devices and related methods of treating diabetic wounds
US20250288716A1 (en) * 2022-12-30 2025-09-18 Süleyman Demirel Üniversitesi Idari Ve Mali Isler Daire Baskanligi Genel Sekreterlik Development of egg white based nanofiber treatment material
CN116459383B (zh) * 2023-02-28 2024-07-19 兰州大学 一种用于促进糖尿病伤口愈合的铈基mof水凝胶及其制备方法和应用
CN118831037B (zh) * 2024-06-28 2025-02-25 广东适配生物科技有限公司 一种负载微球和纳米酶的多功能微针及其制备方法和应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5177065A (en) * 1990-12-26 1993-01-05 Silvetti Sr Anthony N Monosaccharide containing wound healing preparation
US20060231228A1 (en) * 2002-09-13 2006-10-19 Beckman Eric J Formation of hydrogels and use of hydrogels
WO2010010399A2 (en) * 2008-07-24 2010-01-28 Brightwake Limited Honey wound dressing
WO2014165253A1 (en) * 2013-03-12 2014-10-09 Nbip, Llc Compositions and methods for preventing infection of a wound and for advancing the healing process

Family Cites Families (9)

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Publication number Priority date Publication date Assignee Title
IT1232318B (it) * 1989-09-07 1992-01-28 Crinos Industria Farmaco Composizioni ad uso topico contenenti acidi nucleici depolimerizzati per la cosmesi della pelle e del corpo.
FR2854243A1 (fr) * 2003-04-24 2004-10-29 Oreal Procede de determination d'etats pre-alopeciques et/ou d'atteintes cutanees au moyen d'un marqueur predictif: hif-1(hypoxia inducible factor-1)
WO2005123114A2 (en) * 2004-06-11 2005-12-29 Trustees Of Tufts College Silk-based drug delivery system
FR2879443B1 (fr) * 2004-12-21 2007-07-13 Jean Noel Thorel Utilisation d'une base nutritive complexe dans le domaine cosmetique, en particulier capillaire
JPWO2007129618A1 (ja) * 2006-05-08 2009-09-17 国立大学法人 香川大学 好中球の活性化および遊走因子の抑制剤およびその利用
US20110104279A1 (en) * 2009-11-04 2011-05-05 Marraccini Philip A Healing powder and method of use thereof
JP2013521230A (ja) * 2010-02-25 2013-06-10 アルコン リサーチ， リミテッド 角膜創傷治癒を促進する方法
KR20150007276A (ko) * 2011-10-28 2015-01-20 밸리언트 캐나다 엘피 원형탈모증의 예방 및 치료를 위한 인삼 추출물의 사용
GB201703656D0 (en) 2017-03-07 2017-04-19 Univ Sheffield Wound healing medicament

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5177065A (en) * 1990-12-26 1993-01-05 Silvetti Sr Anthony N Monosaccharide containing wound healing preparation
US20060231228A1 (en) * 2002-09-13 2006-10-19 Beckman Eric J Formation of hydrogels and use of hydrogels
WO2010010399A2 (en) * 2008-07-24 2010-01-28 Brightwake Limited Honey wound dressing
WO2014165253A1 (en) * 2013-03-12 2014-10-09 Nbip, Llc Compositions and methods for preventing infection of a wound and for advancing the healing process

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115770322A (zh) * 2022-11-29 2023-03-10 江南大学 一种免疫调节水凝胶及其制备方法和应用
CN115944774A (zh) * 2022-12-04 2023-04-11 吉林大学 一种迷迭香酸-壳聚糖-聚乙烯醇水凝胶敷料及其制备方法和应用

Also Published As

Publication number Publication date
GB201703656D0 (en) 2017-04-19
BR112019018596A2 (pt) 2020-04-07
JP7710206B2 (ja) 2025-07-18
EP3681509C0 (en) 2023-06-07
JP2025172803A (ja) 2025-11-26
EP4233911A3 (en) 2023-09-20
US20210154206A1 (en) 2021-05-27
JP2023078307A (ja) 2023-06-06
US20250099486A1 (en) 2025-03-27
WO2018162900A1 (en) 2018-09-13
EP3681509B1 (en) 2023-06-07
CA3055467A1 (en) 2018-09-13
EP4233911A2 (en) 2023-08-30
ES2955029T3 (es) 2023-11-28
US20250025474A1 (en) 2025-01-23
EP3681509A1 (en) 2020-07-22
JP2020510701A (ja) 2020-04-09
SG11201908060PA (en) 2019-09-27

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