CN110559246A - Itching-dispelling and relieving ointment and preparation method thereof - Google Patents
Itching-dispelling and relieving ointment and preparation method thereof Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61K8/35—Ketones, e.g. benzophenone
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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Abstract
The invention relates to the technical field of daily necessities, and relates to an itching-dispelling and relieving ointment and a preparation method thereof, wherein the itching-dispelling and relieving ointment comprises the following components: ethanol, glycerol, menthol, aloe extract, borneol, camphor, carbomer and triethanolamine, and the balance of water; adding carbomer into water, and stirring; adding menthol, borneol and camphor into ethanol, and stirring uniformly; mixing the solutions obtained in the above two steps, adding glycerol and Aloe extract, and stirring; adding triethanolamine into the mixed solution, homogenizing and stirring to complete the process of preparing the itching-relieving ointment. Compared with the existing itching relieving paste, the itching relieving paste is prepared at normal temperature and normal pressure without heating, so that the preparation process is simple, the heating cost is reduced, and the effect of the effective components of the itching relieving paste is not influenced; compared with similar products, the invention is provided with a new formula for dispelling itch and relieving, so as to be convenient for human body to use.
Description
Technical Field
The invention relates to the technical field of daily necessities, in particular to an itching-dispelling and relieving ointment and a preparation method thereof.
Background
The climate in the south of China is suitable for the survival of mosquitoes, and particularly in spring, summer and autumn, the climate is a season with various mosquitoes; if mosquitoes bite the skin of a human body, the skin may have swelling pain and pruritus, and if the skin is directly grabbed by hands, the skin is easy to be grabbed, so that the swelling pain and the pruritus of the skin are aggravated; usually, some liquid or ointment such as water, essential balm, cooling oil and the like is applied to the place bitten by mosquitoes to relieve the swelling pain and the pruritus of the skin.
The existing itch-dispelling ointment such as cooling oil generally takes paraffin as a carrier, and needs to be melted at high temperature during preparation, the preparation process is complex, the cost is high, and the itch-dispelling ointment is generally sold by using a metal box to bear, so that the processing process becomes more complex; the high-temperature melting of the paraffin has certain influence on the efficacy of the effective components of the itching-dispelling ointment, so that the efficacy of the itching-dispelling ointment is weakened.
disclosure of Invention
the invention aims to provide the paste for dispelling itch and relieving itching and the preparation method thereof, the paste is prepared at normal temperature, the process is simple, the cost is lower, and the effect of the effective components of the paste for dispelling itch and relieving itching is not influenced.
The above object of the present invention is achieved by the following technical solutions:
An itching-dispelling and relieving ointment comprises the following components in percentage by weight: 2-7% of ethanol, 1-5% of glycerol, 1-4% of menthol, 1-4% of aloe extract, 0.1-4% of borneol, 0.1-5% of camphor, 0.1-5% of carbomer, 0.1-5% of triethanolamine and the balance of water.
the invention is further configured to: comprises the following components in percentage by weight: 5% ethanol, 2% glycerol, 2% menthol, 2% aloe extract, 2% borneol, 1% camphor, 0.6% carbomer, 0.6% triethanolamine and the balance water.
The invention is further configured to: the aloe in the aloe extract is extracted by McAnalley and Coats cold treatment, namely, aloe leaves are cleaned and peeled, ground into pulp, removed of cellulose, precipitated with alcohol, centrifugally filtered, frozen and dried to finally prepare the aloe extract in the raw materials.
Another object of the invention is: a preparation method of the itching-dispelling and relieving ointment comprises the following steps:
adding carbomer into water, stirring to obtain solution, and standing;
Adding menthol, borneol and camphor into ethanol, stirring uniformly to obtain a solution, and standing;
mixing the solutions obtained in the two steps, adding glycerol and aloe extract, uniformly stirring to obtain a mixed solution, and standing;
adding triethanolamine into the mixed solution, homogenizing and stirring to complete the process of preparing the itching-relieving ointment.
The invention is further configured to: the method comprises the following steps:
S1: adding carbomer into water, stirring, and standing for 24 hr;
S2: adding menthol, borneol and camphor into ethanol, stirring uniformly, and standing for 30 minutes;
s3: adding S2, glycerol and Aloe extract into S1, stirring, and standing for 2 hr;
S4: adding triethanolamine into S3, homogenizing and stirring for 10 min to obtain the final product.
The invention is further configured to: the itching relieving ointment is kept still for at least 12 hours and then can be filled.
By adopting the technical scheme: the itching relieving paste is similar to toothpaste without adding paraffin, so that the loading process of the itching relieving paste is simplified, the cost is reduced, and the economic benefit of the itching relieving paste is improved.
In conclusion, the beneficial technical effects of the invention are as follows:
1. compared with the existing itching relieving paste, the itching relieving paste is prepared at normal temperature and normal pressure without heating, so that the preparation process is simple, the heating cost is reduced, and the effect of the effective components of the itching relieving paste is not influenced; compared with the similar products, the invention is provided with a new formula for dispelling itch and relieving, so as to be convenient for the human body to use;
2. The itching relieving cream does not need to be loaded by a metal box, and the loading mode of the itching relieving cream is simplified, so that the cost is reduced, and the economic efficiency of the itching relieving cream is improved.
Drawings
FIG. 1 is a process flow chart of the present invention for preparing the itch-relieving ointment.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings.
example 1
An ointment for relieving itching and soothing comprises, by weight, 2% of ethanol, 1% of glycerol, 1% of menthol, 0.5% of aloe extract, 0.2% of borneol, 0.2% of camphor, 0.1% of carbomer, 0.1% of triethanolamine and the balance of water. The aloe in the aloe extract is extracted by McAnalley and Coats cold treatment, which comprises cleaning and peeling the leaves of aloe, grinding into slurry, removing cellulose, precipitating with ethanol, centrifuging, filtering, and freeze drying to obtain the aloe extract.
The itching-dispelling and relieving ointment is prepared by the following method, and comprises the following steps:
referring to fig. 1, at normal temperature and pressure, step one, adding carbomer into water, stirring uniformly, standing for 24 hours to enable carbomer to be completely dissolved into water for later use;
Step two, adding the menthol, the borneol and the camphor into the ethanol, stirring uniformly, and standing for 30 minutes to enable the menthol, the borneol, the camphor and the ethanol to be mutually fused for later use;
Step three, adding the solution obtained in the step two, glycerol and aloe extract into the solution obtained in the step one, stirring uniformly to enable carbomer, water, menthol, borneol, camphor, ethanol, glycerol and aloe extract to be mutually fused, and standing for 2 hours for later use;
and step four, adding triethanolamine into the mixed solution obtained in the step three, homogenizing and stirring for 10 minutes to enable carbomer, water, menthol, borneol, camphor, ethanol, glycerin, the aloe extract and the triethanolamine to be mutually fused, and finishing the preparation process of the itching-relieving ointment.
The prepared itching relieving cream is kept stand for 12 hours and then filled into a bottle by a filling machine so as to facilitate the sale of the itching relieving cream.
example 2
An ointment for relieving itching comprises, by weight, 3% of ethanol, 2% of glycerol, 2% of menthol, 1% of aloe extract, 0.4% of borneol, 0.4% of camphor, 0.4% of carbomer, 0.3% of triethanolamine and the balance of water. The aloe in the aloe extract is extracted by McAnalley and Coats cold treatment, which comprises cleaning and peeling the leaves of aloe, grinding into slurry, removing cellulose, precipitating with ethanol, centrifuging, filtering, and freeze drying to obtain the aloe extract.
The itching-dispelling and relieving ointment is prepared by the following method, and comprises the following steps:
referring to fig. 1, at normal temperature and pressure, step one, adding carbomer into water, stirring uniformly, standing for 24 hours to enable carbomer to be completely dissolved into water for later use;
Step two, adding the menthol, the borneol and the camphor into the ethanol, stirring uniformly, and standing for 30 minutes to enable the menthol, the borneol, the camphor and the ethanol to be mutually fused for later use;
step three, adding the solution obtained in the step two, glycerol and aloe extract into the solution obtained in the step one, stirring uniformly to enable carbomer, water, menthol, borneol, camphor, ethanol, glycerol and aloe extract to be mutually fused, and standing for 2 hours for later use;
and step four, adding triethanolamine into the mixed solution obtained in the step three, homogenizing and stirring for 10 minutes to enable carbomer, water, menthol, borneol, camphor, ethanol, glycerin, the aloe extract and the triethanolamine to be mutually fused, and finishing the preparation process of the itching-relieving ointment.
the prepared itching relieving cream is kept stand for 12 hours and then filled into a bottle by a filling machine so as to facilitate the sale of the itching relieving cream.
Example 3
an itching-relieving ointment comprises, by weight, 4% of ethanol, 3% of glycerol, 3% of menthol, 2% of aloe extract, 1% of borneol, 0.7% of camphor, 0.8% of carbomer, 0.9% of triethanolamine and the balance of water. The aloe in the aloe extract is extracted by McAnalley and Coats cold treatment, which comprises cleaning and peeling the leaves of aloe, grinding into slurry, removing cellulose, precipitating with ethanol, centrifuging, filtering, and freeze drying to obtain the aloe extract.
Referring to fig. 1, the itch-relieving ointment is prepared by the following method, including the following steps:
At normal temperature and normal pressure, step one, adding carbomer into water, stirring uniformly, standing for 24 hours to enable carbomer to be completely dissolved into water for later use;
step two, adding the menthol, the borneol and the camphor into the ethanol, stirring uniformly, and standing for 30 minutes to enable the menthol, the borneol, the camphor and the ethanol to be mutually fused for later use;
Step three, adding the solution obtained in the step two, glycerol and aloe extract into the solution obtained in the step one, stirring uniformly to enable carbomer, water, menthol, borneol, camphor, ethanol, glycerol and aloe extract to be mutually fused, and standing for 2 hours for later use;
And step four, adding triethanolamine into the mixed solution obtained in the step three, homogenizing and stirring for 10 minutes to enable carbomer, water, menthol, borneol, camphor, ethanol, glycerin, the aloe extract and the triethanolamine to be mutually fused, and finishing the preparation process of the itching-relieving ointment.
the prepared itching relieving cream is kept stand for 12 hours and then filled into a bottle by a filling machine so as to facilitate the sale of the itching relieving cream.
Example 4
an itching-relieving ointment comprises, by weight, 5% of ethanol, 4% of glycerol, 4% of menthol, 3% of aloe extract, 2% of borneol, 1.2% of camphor, 1.5% of carbomer, 1.2% of triethanolamine and the balance of water. The aloe in the aloe extract is extracted by McAnalley and Coats cold treatment, which comprises cleaning and peeling the leaves of aloe, grinding into slurry, removing cellulose, precipitating with ethanol, centrifuging, filtering, and freeze drying to obtain the aloe extract.
referring to fig. 1, the itch-relieving ointment is prepared by the following method, including the following steps:
At normal temperature and normal pressure, step one, adding carbomer into water, stirring uniformly, standing for 24 hours to enable carbomer to be completely dissolved into water for later use;
Step two, adding the menthol, the borneol and the camphor into the ethanol, stirring uniformly, and standing for 30 minutes to enable the menthol, the borneol, the camphor and the ethanol to be mutually fused for later use;
Step three, adding the solution obtained in the step two, glycerol and aloe extract into the solution obtained in the step one, stirring uniformly to enable carbomer, water, menthol, borneol, camphor, ethanol, glycerol and aloe extract to be mutually fused, and standing for 2 hours for later use;
And step four, adding triethanolamine into the mixed solution obtained in the step three, homogenizing and stirring for 10 minutes to enable carbomer, water, menthol, borneol, camphor, ethanol, glycerin, the aloe extract and the triethanolamine to be mutually fused, and finishing the preparation process of the itching-relieving ointment.
the prepared itching relieving cream is kept stand for 12 hours and then filled into a bottle by a filling machine so as to facilitate the sale of the itching relieving cream.
example 5
An ointment for relieving itching comprises, by weight, 6% of ethanol, 5% of glycerol, 4% of menthol, 4% of aloe extract, 3% of borneol, 2.3% of camphor, 2.5% of carbomer, 3% of triethanolamine and the balance of water. The aloe in the aloe extract is extracted by McAnalley and Coats cold treatment, which comprises cleaning and peeling the leaves of aloe, grinding into slurry, removing cellulose, precipitating with ethanol, centrifuging, filtering, and freeze drying to obtain the aloe extract.
Referring to fig. 1, the itch-relieving ointment is prepared by the following method, including the following steps:
at normal temperature and normal pressure, step one, adding carbomer into water, stirring uniformly, standing for 24 hours to enable carbomer to be completely dissolved into water for later use;
Step two, adding the menthol, the borneol and the camphor into the ethanol, stirring uniformly, and standing for 30 minutes to enable the menthol, the borneol, the camphor and the ethanol to be mutually fused for later use;
Step three, adding the solution obtained in the step two, glycerol and aloe extract into the solution obtained in the step one, stirring uniformly to enable carbomer, water, menthol, borneol, camphor, ethanol, glycerol and aloe extract to be mutually fused, and standing for 2 hours for later use;
and step four, adding triethanolamine into the mixed solution obtained in the step three, homogenizing and stirring for 10 minutes to enable carbomer, water, menthol, borneol, camphor, ethanol, glycerin, the aloe extract and the triethanolamine to be mutually fused, and finishing the preparation process of the itching-relieving ointment.
The prepared itching relieving cream is kept stand for 12 hours and then filled into a bottle by a filling machine so as to facilitate the sale of the itching relieving cream.
example 6
An ointment for relieving itching and soothing comprises, by weight, 7% of ethanol, 5% of glycerin, 4% of menthol, 4% of aloe extract, 4% of borneol, 4.5% of camphor, 4% of carbomer, 5% of triethanolamine and the balance of water. The aloe in the aloe extract is extracted by McAnalley and Coats cold treatment, which comprises cleaning and peeling the leaves of aloe, grinding into slurry, removing cellulose, precipitating with ethanol, centrifuging, filtering, and freeze drying to obtain the aloe extract.
referring to fig. 1, the itch-relieving ointment is prepared by the following method, including the following steps:
at normal temperature and normal pressure, step one, adding carbomer into water, stirring uniformly, standing for 24 hours to enable carbomer to be completely dissolved into water for later use;
step two, adding the menthol, the borneol and the camphor into the ethanol, stirring uniformly, and standing for 30 minutes to enable the menthol, the borneol, the camphor and the ethanol to be mutually fused for later use;
step three, adding the solution obtained in the step two, glycerol and aloe extract into the solution obtained in the step one, stirring uniformly to enable carbomer, water, menthol, borneol, camphor, ethanol, glycerol and aloe extract to be mutually fused, and standing for 2 hours for later use;
and step four, adding triethanolamine into the mixed solution obtained in the step three, homogenizing and stirring for 10 minutes to enable carbomer, water, menthol, borneol, camphor, ethanol, glycerin, the aloe extract and the triethanolamine to be mutually fused, and finishing the preparation process of the itching-relieving ointment.
The prepared itching relieving cream is kept stand for 12 hours and then filled into a bottle by a filling machine so as to facilitate the sale of the itching relieving cream.
example 7
an ointment for relieving itching comprises, by weight, 5% of ethanol, 2% of glycerol, 2% of menthol, 2% of aloe extract, 2% of borneol, 1% of camphor, 0.6% of carbomer, 0.6% of triethanolamine and the balance of water. The aloe in the aloe extract is extracted by McAnalley and Coats cold treatment, which comprises cleaning and peeling the leaves of aloe, grinding into slurry, removing cellulose, precipitating with ethanol, centrifuging, filtering, and freeze drying to obtain the aloe extract.
Referring to fig. 1, the itch-relieving ointment is prepared by the following method, including the following steps:
at normal temperature and normal pressure, step one, adding carbomer into water, stirring uniformly, standing for 24 hours to enable carbomer to be completely dissolved into water for later use;
Step two, adding the menthol, the borneol and the camphor into the ethanol, stirring uniformly, and standing for 30 minutes to enable the menthol, the borneol, the camphor and the ethanol to be mutually fused for later use;
step three, adding the solution obtained in the step two, glycerol and aloe extract into the solution obtained in the step one, stirring uniformly to enable carbomer, water, menthol, borneol, camphor, ethanol, glycerol and aloe extract to be mutually fused, and standing for 2 hours for later use;
And step four, adding triethanolamine into the mixed solution obtained in the step three, homogenizing and stirring for 10 minutes to enable carbomer, water, menthol, borneol, camphor, ethanol, glycerin, the aloe extract and the triethanolamine to be mutually fused, and finishing the preparation process of the itching-relieving ointment.
The prepared itching relieving cream is kept stand for 12 hours and then filled into a bottle by a filling machine so as to facilitate the sale of the itching relieving cream.
Volunteers 210 were randomly recruited and randomly divided into 7 groups of 30 persons, and the itch-relieving cream prepared in examples 1 to 7 was distributed, and when the skin was bitten by mosquitoes within one month, the itch-relieving cream was applied to the bitten area, and data on their use of the itch-relieving cream was collected, and the following table was obtained:
| Itch dispelling | relief and relieve | no effect | |
| Example 1 | 22 | 17 | 7 |
| Example 2 | 23 | 20 | 5 |
| Example 3 | 28 | 27 | 2 |
| example 4 | 29 | 28 | 3 |
| Example 5 | 28 | 29 | 2 |
| Example 6 | 28 | 29 | 2 |
| Example 7 | 29 | 28 | 3 |
itch dispelling: the itching-relieving ointment is applied to the mosquito bite to relieve itching;
Relieving: the itching-relieving ointment is applied to the mosquito bite, and convex hulls generated by the mosquito bite are recovered to play a role in relieving the skin;
no effect: the ointment for dispelling itch and relieving itching is applied to the mosquito bite part, although the ointment has a certain effect, the same effect can be achieved by using water and other substitutes, and particularly, the effect is not obvious.
It can be seen that the sample soothing creams of examples 3 to 7 all give better results, and the itch-relieving cream of example 7 is preferably prepared in view of the cost of raw materials.
The embodiments of the present invention are preferred embodiments of the present invention, and the scope of the present invention is not limited by these embodiments, so: all equivalent changes made according to the structure, shape and principle of the invention are covered by the protection scope of the invention.
Claims (6)
1. The itching-dispelling and relieving ointment is characterized by comprising the following components in percentage by weight: 2-7% of ethanol, 1-5% of glycerol, 1-4% of menthol, 1-4% of aloe extract, 0.1-4% of borneol, 0.1-5% of camphor, 0.1-5% of carbomer, 0.1-5% of triethanolamine and the balance of water.
2. The ointment of claim 1, which comprises the following components by weight percent: 5% ethanol, 2% glycerol, 2% menthol, 2% aloe extract, 2% borneol, 1% camphor, 0.6% carbomer, 0.6% triethanolamine and the balance water.
3. the ointment of claim 1, wherein the aloe vera in the aloe vera extract is extracted by McAnalley and Coats cold process, which comprises washing and peeling the leaves of aloe vera, grinding to a slurry, removing the cellulose, precipitating with ethanol, centrifuging, filtering, freeze drying, and finally obtaining the aloe vera extract from the raw material.
4. a process for preparing an itch-relieving ointment according to claim 1 or 2, which comprises:
adding carbomer into water, stirring to obtain solution, and standing;
adding menthol, borneol and camphor into ethanol, stirring uniformly to obtain a solution, and standing;
Mixing the solutions obtained in the two steps, adding glycerol and aloe extract, uniformly stirring to obtain a mixed solution, and standing;
adding triethanolamine into the mixed solution, homogenizing and stirring to complete the process of preparing the itching-relieving ointment.
5. The method for preparing the itching-relieving ointment as claimed in claim 4, wherein the method comprises the following steps at normal temperature and normal pressure:
S1: adding carbomer into water, stirring, and standing for 24 hr;
s2: adding menthol, borneol and camphor into ethanol, stirring uniformly, and standing for 30 minutes;
S3: adding S2, glycerol and Aloe extract into S1, stirring, and standing for 2 hr;
S4: adding triethanolamine into S3, homogenizing and stirring for 10 min to obtain the final product.
6. the method for preparing the paste according to claim 5, wherein the paste is left for at least 12 hours and then filled.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115737734A (en) * | 2022-11-04 | 2023-03-07 | 双飞人制药股份有限公司 | A composition with refreshing and antipruritic effects |
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| CN101444588A (en) * | 2008-12-26 | 2009-06-03 | 漳州市健源堂生物工程有限公司 | Skin ointment and preparation method thereof |
| CN105770237A (en) * | 2016-04-22 | 2016-07-20 | 广东红珊瑚药业有限公司 | Foaming agent with itching-relieving and inflammation-diminishing effects and preparation method of foaming agent |
| CN107519154A (en) * | 2017-09-01 | 2017-12-29 | 广东名辰堂健康产业股份有限公司 | It is a kind of that there is antiallergy, plant extraction liquid topical composition that only trace is itched and preparation method thereof |
| CN107510773A (en) * | 2017-09-05 | 2017-12-26 | 肇庆高新区国专科技有限公司 | A kind of pure plant extract solution and preparation method thereof |
| CN107519372A (en) * | 2017-09-05 | 2017-12-29 | 肇庆高新区国专科技有限公司 | It is a kind of that there is antiallergy, plant extraction liquid that only trace is itched and preparation method thereof |
| CN108420929A (en) * | 2018-04-15 | 2018-08-21 | 啵噜噜（广州）婴儿用品科技有限公司 | A kind of external preparation with the miliaria itching-relieving action that relaxes |
| CN110151656A (en) * | 2019-06-24 | 2019-08-23 | 五邑大学 | Plant source property mosquito-expelling and antipruritic anti-inflammatory ointment and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN115737734A (en) * | 2022-11-04 | 2023-03-07 | 双飞人制药股份有限公司 | A composition with refreshing and antipruritic effects |
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