CN107519372A - It is a kind of that there is antiallergy, plant extraction liquid that only trace is itched and preparation method thereof - Google Patents
It is a kind of that there is antiallergy, plant extraction liquid that only trace is itched and preparation method thereof Download PDFInfo
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- CN107519372A CN107519372A CN201710789217.9A CN201710789217A CN107519372A CN 107519372 A CN107519372 A CN 107519372A CN 201710789217 A CN201710789217 A CN 201710789217A CN 107519372 A CN107519372 A CN 107519372A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
- A61K31/125—Camphor; Nuclear substituted derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- Oil, Petroleum & Natural Gas (AREA)
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Abstract
The present invention disclose it is a kind of with antiallergy, stop the plant extraction liquid itched of trace, the weight proportion of its composition includes：20 ~ 30 parts of deionized water；6 ~ 20 parts of aloe squeezeding juice；6 ~ 15 parts of Chinese herbaceous peony；6 ~ 20 parts of glycerine；5 ~ 20 parts of menthol；1 ~ 5 part of camphor；1 ~ 5 part of borneol；0.2 ~ 3 part of dipotassium glycyrrhizinate；0.1 ~ 3 part of Phenoxyethanol.And raw material, stirring and dissolving is taken to discharge afterwards completely successively.It can reach with antiallergy, the effect that only trace is itched.
Description
Technical field
There is antiallergy, plant extraction liquid that only trace is itched and preparation method thereof the present invention relates to a kind of.
Background technology
Biotechnology extract solution, refer to people based on modern life science, the science with reference to other basic science is former
Reason, using advanced scientific and technological means, according to advance design improvement organism or processing biological raw material, produced for the mankind
Required product reaches certain purpose.
Most of at present have antiallergy, a medicine that only trace is itched, most of prepared using hormonal medicaments or chemical reagent and
Into therefore, people can bring more side effect simultaneously when using the medicine.
Therefore, according to the defects of above-mentioned deduction, be badly in need of on the market it is a kind of with antiallergy, only the plant extraction liquid itched of trace and
Its preparation method.
The content of the invention
Based on this, it is necessary to the shortcomings that for above-mentioned deduction and shortcoming technical problem, there is provided one kind has antiallergy, only
Plant extraction liquid that trace is itched and preparation method thereof.
It is a kind of to include with antiallergy, the plant extraction liquid that only trace is itched, the weight proportion of its composition：
20 ~ 30 parts of deionized water；
6 ~ 20 parts of aloe squeezeding juice；
6 ~ 15 parts of Chinese herbaceous peony；
6 ~ 10 parts of glycerine；
6 ~ 10 parts of menthol；
1 ~ 5 part of camphor；
1 ~ 5 part of borneol；
0.2 ~ 3 part of dipotassium glycyrrhizinate；
0.1 ~ 3 part of Phenoxyethanol.
It is a kind of with antiallergy, the preparation method of plant extraction liquid that only trace is itched, it include it is described above it is a kind of have resist
Allergy, the plant extraction liquid that only trace is itched, the preparation method comprise the following steps：
A. water, the glycerine of suitable deal are taken successively, while are put into agitated kettle；
B. one-shot agitated kettle, mixing speed are 30 revs/min, and mixing time suspends agitated kettle after 10-15 minutes, pause
After minute time 1-3, motor reversal stirs 30 revs/min, and pause agitated kettle is stirred and carried out down after mixing time 10-15 minutes
One step；
C. take ethanol, menthol, camphor, the borneol of suitable deal to be dissolved in a container successively, enter after dissolving completely
Next step；
D. by the ethanol after dissolving, menthol, camphor, borneol mixture input agitated kettle；
E. it is again started up agitated kettle, mixing speed is 30 revs/min, and mixing time suspends agitated kettle after 18-25 minutes, during pause
Between after 15-30 minutes, motor reversal stirs 30 revs/min, and pause agitated kettle is stirred and carried out down after mixing time 10-15 minutes
One step；
F. the dipotassium glycyrrhizinate of suitable deal, Phenoxyethanol are taken successively while are put into agitated kettle；
G. third time starts agitated kettle, and mixing speed is 30 revs/min, and mixing time makes motor reversal stir again after 18-25 minutes
Minute time 3-5 is mixed, then stops stirring, and make material in agitated kettle static；
H. take out material in agitated kettle and place low temperature chamber, static to place 30 minutes, preparation method is completed.
As the further optimization of above-mentioned technical proposal, in the step c, ethanol, menthol, camphor, borneol hold in one
When being dissolved in device, add stirring rod and be stirred, mixing speed is 30 revs/min, mixing time 10-15 minutes.
As the further optimization of above-mentioned technical proposal, in the step h, the atmospheric temperature of the low temperature chamber for -5 DEG C ~
16℃。
The present invention it is a kind of with antiallergy, only plant extraction liquid for itching of trace and preparation method thereof, by above-mentioned setting, its
It can reach with antiallergy, the effect that only trace is itched.
Embodiment
The a kind of of one embodiment of the invention offer has antiallergy, plant extraction liquid that only trace is itched and preparation method thereof.
It is a kind of to include with antiallergy, the plant extraction liquid that only trace is itched, the weight proportion of its composition in a kind of embodiment：
20 ~ 30 parts of deionized water；
6 ~ 20 parts of aloe squeezeding juice；
6 ~ 15 parts of Chinese herbaceous peony；
6 ~ 10 parts of glycerine；
6 ~ 10 parts of menthol；
1 ~ 5 part of camphor；
1 ~ 5 part of borneol；
0.2 ~ 3 part of dipotassium glycyrrhizinate；
0.1 ~ 3 part of Phenoxyethanol.
Glycerine refers generally to glycerine, and national standard is referred to as glycerine, colourless, odorless, sweet, and outward appearance is in clear and bright viscous liquid state,
It is a kind of organic matter.Glycerine, moisture can be absorbed from air, can also absorb hydrogen sulfide, hydrogen cyanide and sulfur dioxide.It is insoluble in
Benzene, chloroform, carbon tetrachloride, carbon disulfide, petroleum ether and oils.Glycerine is the framework ingredient of triglycerides molecule.It is relatively close
Degree 1.26362.17.8 DEG C of fusing point.290.0 DEG C of boiling point（Decompose）.Index of refraction 1.4746.Flash-point（Open cup）176℃.The present embodiment
Signified glycerine, is the method using natural oil as raw material, also referred to as natural glycerin.
Menthol, a kind of chemical agent, menthol in the leaf and stem of peppermint by being extracted, white crystal, molecular formula
C10H20O, it is the main component in peppermint and lavender essential oil.Menthol described in the present embodiment, using overcritical titanium dioxide
The menthol that carbon extracts from peppermint（Menthol）.
Camphor is the branch, dry, leaf and root of canella camphor tree, through crystalline particulate made from refinement.Thick camphor generally exists
Winter processing is raw material with 50 years raw above camphor tree trunks and root, and water proof distills in wooden rice steamer after chipping, camphor and camphor
Oil distillates with vapor, and condensation gained white crystal is thick camphor, and oily liquids is camphorated oil.Total yield 2.0~2.5%.Thick camphor tree
Brain is refined two methods of blowing sublimed method and continuous rectification sublimed method.China is based on sublimed method of drying.Thick camphor first pass through from
Scheming is put into the melting of distillation pot, distillation except deoiling and water, and the air that camphor steam enters with pot top blast is concomitantly introduced into the 1st sublimation chamber,
Control chilling temperature obtains powdered crystalline finished product.The 2nd, cut of the 3rd sublimation chamber is subsequently entered, because control temperature is relatively low, low boiling point
In camphor moisture and oil in company with a small amount of camphor steam in this condensation-crystallization, be camphor crude product（Oil-containing water more than 8%）, need weight
New sublimation purifying.Chinese natural Gum Camphor has two kinds of powdery and bulk.Quality meets pharmacopoeia of each country specification：Fusing point 174~179
DEG C ,+41 °~+43 ° of specific rotation village, often used in village names（20% in ethanol）, for nonvolatile matter below 0.05%, moisture meets 1 gram plus the milli of petroleum ether 10
Rise clarification dissolving.
Borneol, it is to be obtained by composite family Blumea balsamifera cauline leaf or canella borneol camphor tree branches and leaves through steam distillation and recrystallization.
Also useful turpentine oil obtains through a series of chemical method techniques.
Dipotassium glycyrrhizinate is white or off-white color fine powder, and purity has a special sweet taste up to 98%, it is water-soluble it is good, mouthfeel is pure.It is sweet
Oxalic acid dipotassium has the multiple efficacies such as antibacterial, anti-inflammatory, removing toxic substances, antiallergic, deodorization.Have in the industry such as medicine, cosmetics daily use chemicals, food
It is widely applied.It is neutralized and obtained using radix glycyrrhizae as raw material completely with water extracting back end hydrogenation potassium oxide or potassium carbonate.
Phenoxyethanol is a kind of organic compound for being frequently used for skin-protection product, can be formed by ethylene glycol and phenol etherificate,
It is common in face cream and suncream.Phenoxyethanol is a kind of colourless oily liquids, there is antibiotic effect, often in biological buffering
It is used as the substitute for having the sodium azide of severe toxicity in solution.In the present embodiment, Phenoxyethanol is mixed by sodium phenate with chlorethanol
Chemical reaction forms.
In a kind of embodiment, a kind of preparation method for having antiallergy, stopping the plant extraction liquid that trace is itched, it is included as described above
It is a kind of with antiallergy, only the plant extraction liquid itched of trace, the preparation method comprise the following steps：
A. water, the glycerine of suitable deal are taken successively, while are put into agitated kettle.
B. one-shot agitated kettle, mixing speed are 30 revs/min, and mixing time suspends agitated kettle after 10-15 minutes,
After time out 1-3 minutes, motor reversal stirs 30 revs/min, suspends agitated kettle stirring after mixing time 10-15 minutes and goes forward side by side
Row next step；
C. take ethanol, menthol, camphor, the borneol of suitable deal to be dissolved in a container successively, enter after dissolving completely
Next step；
D. by the ethanol after dissolving, menthol, camphor, borneol mixture input agitated kettle；
E. it is again started up agitated kettle, mixing speed is 30 revs/min, and mixing time suspends agitated kettle after 18-25 minutes, during pause
Between after 15-30 minutes, motor reversal stirs 30 revs/min, and pause agitated kettle is stirred and carried out down after mixing time 10-15 minutes
One step；
F. the dipotassium glycyrrhizinate of suitable deal, Phenoxyethanol are taken successively while are put into agitated kettle；
G. third time starts agitated kettle, and mixing speed is 30 revs/min, and mixing time makes motor reversal stir again after 18-25 minutes
Minute time 3-5 is mixed, then stops stirring, and make material in agitated kettle static；
H. take out material in agitated kettle and place low temperature chamber, static to place 30 minutes, preparation method is completed.
In a kind of embodiment, in the step c, when ethanol, menthol, camphor, borneol are dissolved in a container, add
Enter stirring rod to be stirred, mixing speed is 30 revs/min, mixing time 10-15 minutes.In the present embodiment, mixing time
Specially 10 minutes.
In a kind of embodiment, in the step h, the atmospheric temperature of the low temperature chamber is -5 DEG C ~ 16 DEG C.The low temperature chamber is
Closed chamber.
Each technical characteristic of embodiment described above can be combined arbitrarily, to make description succinct, not to above-mentioned reality
Apply all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, the scope that this specification is recorded all is considered to be.
Embodiment described above only expresses the several embodiments of the present invention, and its description is more specific and detailed, but simultaneously
Can not therefore it be construed as limiting the scope of the patent.It should be pointed out that come for one of ordinary skill in the art
Say, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the protection of the present invention
Scope.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.
Claims (4)
- It is 1. a kind of with antiallergy, the plant extraction liquid that only trace is itched, it is characterised in that the weight proportion of composition includes：20 ~ 30 parts of deionized water；6 ~ 20 parts of aloe squeezeding juice；6 ~ 15 parts of Chinese herbaceous peony；6 ~ 10 parts of glycerine；6 ~ 10 parts of menthol；1 ~ 5 part of camphor；1 ~ 5 part of borneol；0.2 ~ 3 part of dipotassium glycyrrhizinate；0.1 ~ 3 part of Phenoxyethanol.
- 2. a kind of preparation method that there is antiallergy, stop the plant extraction liquid that trace is itched, it is characterised in that including such as claim 1 Described is a kind of with antiallergy, the plant extraction liquid that only trace is itched, it is characterised in that the preparation method comprises the following steps：A. the deionized water of suitable deal, aloe squeezeding juice, Chinese herbaceous peony, glycerine are taken successively, while are put into agitated kettle；B. one-shot agitated kettle, mixing speed are 30 revs/min, and mixing time suspends agitated kettle after 10-15 minutes, pause After minute time 1-3, motor reversal stirs 30 revs/min, and pause agitated kettle is stirred and carried out down after mixing time 10-15 minutes One step；C. take ethanol, menthol, camphor, the borneol of suitable deal to be dissolved in a container successively, enter after dissolving completely Next step；D. by the ethanol after dissolving, menthol, camphor, borneol mixture input agitated kettle；E. it is again started up agitated kettle, mixing speed is 30 revs/min, and mixing time suspends agitated kettle after 18-25 minutes, during pause Between after 15-30 minutes, motor reversal stirs 30 revs/min, and pause agitated kettle is stirred and carried out down after mixing time 10-15 minutes One step；F. the dipotassium glycyrrhizinate of suitable deal, Phenoxyethanol are taken successively while are put into agitated kettle；G. third time starts agitated kettle, and mixing speed is 30 revs/min, and mixing time makes motor reversal stir again after 18-25 minutes Minute time 3-5 is mixed, then stops stirring, and make material in agitated kettle static；H. take out material in agitated kettle and place low temperature chamber, static to place 30 minutes, preparation method is completed.
- 3. a kind of preparation method for having antiallergy, stopping the plant extraction liquid that trace is itched according to claim 2, its feature exist In, in the step c, when ethanol, menthol, camphor, borneol are dissolved in a container, add stirring rod and be stirred, Mixing speed is 30 revs/min, mixing time 10-15 minutes.
- 4. a kind of preparation method for having antiallergy, stopping the plant extraction liquid that trace is itched according to claim 2, its feature exist In in the step h, the atmospheric temperature of the low temperature chamber is -5 DEG C ~ 16 DEG C.
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| CN201710789217.9A CN107519372A (en) | 2017-09-05 | 2017-09-05 | It is a kind of that there is antiallergy, plant extraction liquid that only trace is itched and preparation method thereof |
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| CN201710789217.9A CN107519372A (en) | 2017-09-05 | 2017-09-05 | It is a kind of that there is antiallergy, plant extraction liquid that only trace is itched and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110559246A (en) * | 2019-11-06 | 2019-12-13 | 珠海市宝丽金化妆品有限公司 | Itching-dispelling and relieving ointment and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110559246A (en) * | 2019-11-06 | 2019-12-13 | 珠海市宝丽金化妆品有限公司 | Itching-dispelling and relieving ointment and preparation method thereof |
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