CN110522880A - A kind of Chinese medicine composition for preventing and treating laying hen mycotoxicosis, Chinese medicine microecological preparation and preparation method thereof - Google Patents
A kind of Chinese medicine composition for preventing and treating laying hen mycotoxicosis, Chinese medicine microecological preparation and preparation method thereof Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/634—Forsythia
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/884—Alismataceae (Water-plantain family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
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- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
Abstract
The Chinese medicine composition that the present invention relates to a kind of for preventing and treating laying hen mycotoxicosis, Chinese medicine microecological preparation and preparation method thereof.The Chinese medicine composition is made of the raw material of following parts by weight: 15~25 parts of radix scutellariae, 15~25 parts of cape jasmine, 55~65 parts of Fructus Forsythiae, 45~55 parts of Fructus Aurantii, 55~65 parts of Radix Curcumae, 55~65 parts of Radix Angelicae Sinensis, 35~45 parts of Rhizoma Chuanxiong, 35~45 parts of radix paeoniae rubra, 55~65 parts of Radix Astragali, 55~65 parts of Rhizoma Atractylodis Macrocephalae, 55~65 parts of rhizoma alismatis, 75~85 parts of Poria cocos, 35~45 parts of Radix Glycyrrhizae.It is injured for bodies such as lesions of liver and kidney caused by mycotoxin, above-mentioned Chinese medicine composition has certain repair, can be improved laying hen immunity of organisms and hepatic and renal function, promotes degradation and tolerance of the body to mycotoxin, mitigate harm of the mycotoxin to laying hen, improves the production performance of laying hen.
Description
Technical field
Veterinary Chinese medicine preparation field of the present invention, and in particular to a kind of for preventing and treating the Chinese traditional medicine composition of laying hen mycotoxicosis
Object, Chinese medicine microecological preparation and preparation method thereof.
Background technique
Nutriment rich in, is highly prone to mould contamination and goes mouldy in feed, and it is agreeable to the taste not only to influence feed
Property, nutritive value is reduced, and serious harm is caused to the health of husbandry sector, food safety and the mankind.According to joint
Food and agricultural organization, state report, the whole world reaches 25% or more by the cereal of mycotoxin contamination every year, caused by economic loss up to number
$ 100 billion.Currently, reported mycotoxin there are more than 300 kinds, humans and animals health is caused in food and feed potential
About 20 kinds of the toxin of harm.It is common to cause the mycotoxin of economic loss mainly to have aflatoxin laying hen production
(aflatoxin, AFT), vomitoxin (deoxynivalenol, DON) and zearalenone (zearalenone, ZEN)
Deng mainly causing laying hen feed intake and egg production to decline, Egg Quality reduces, immunity of organisms reduces, morbidity and mortality liter
Height, meanwhile, also cause the organ damages such as liver, kidney.Therefore, how to inhibit the growth and breeding of mould in feed, reduce mould in feed
The content of verticillium toxin reduces mycotoxin and loses to caused by livestock products production, becomes feed and cultivation industry is urgently to be resolved
One significant problem.
Publication No. is that the patent application of CN105124195A discloses a kind of preparation method of feed addictive of layer chicken, is
Montmorillonite, humic acid are added in saccharomycetes to make fermentation liquid and fermentation of bacillus liquid, the pH value for adjusting fermentation liquid is 8.5-9,
After vibrating 10-15h, the complex for air-drying, crushing, then complex is uniformly mixed with other raw materials and is made.The feed addictive
Although can be reduced the content of mycotoxin to a certain extent, also there are many defects in actual production, for example, montmorillonite etc.
Can absorbing mycotoxin, but also can adsorb the nutritional ingredients such as vitamin, microelement and amino acid and reduce the benefit of nutriment
With rate, meanwhile, the toxin of absorption is possible to discharge again in animal gastrointestinal tract, be not metabolized or the toxin that discharges again still
Laying hen body and production performance can so be impacted.
In terms of comprehensive, during layer breeding, it unavoidably will receive the invasion of mycotoxin, existing feed addictive is inclined
The degradation of mycotoxin is overweighted, but since resistance and tolerance of the laying hen body to mycotoxin are poor, caused to prevention and treatment laying hen
The effect of mycotoxicosis is poor.
Summary of the invention
The purpose of the present invention is to provide a kind of for preventing and treating the Chinese medicine composition of laying hen mycotoxicosis, to solve
Existing feed addictive of layer chicken can not improve the problem of resistance and tolerance of the laying hen body to mycotoxin.
The Chinese medicine microecological preparation and its preparation side that the present invention also provides a kind of for preventing and treating laying hen mycotoxicosis
Method.
To achieve the above object, the technical scheme adopted by the invention is that:
It is a kind of for preventing and treating the Chinese medicine composition of laying hen mycotoxicosis, be made of the raw material of following parts by weight: radix scutellariae
15~25 parts, 15~25 parts of cape jasmine, 55~65 parts of Fructus Forsythiae, 45~55 parts of Fructus Aurantii, 55~65 parts of Radix Curcumae, 55~65 parts of Radix Angelicae Sinensis, river
35~45 parts of rhizome of chuanxiong, 35~45 parts of radix paeoniae rubra, 55~65 parts of Radix Astragali, 55~65 parts of Rhizoma Atractylodis Macrocephalae, 55~65 parts of rhizoma alismatis, 75~85 parts of Poria cocos,
35~45 parts of Radix Glycyrrhizae.
Below in Chinese medicine composition, the characteristic of each bulk pharmaceutical chemicals is illustrated:
Radix scutellariae: for the dry root of Lamiaceae plant radix scutellariae；Containing baicalein, scutelloside, double scutellosides, wogonoside, can
Add the effective components such as baicalein, skullcapflavone I；Nature and flavor are cold, bitter；Return heart, lung, gallbladder, large intestine channel；Effect is heat-clearing and damp-drying drug, purging intense heat
Removing toxic substances, hemostasis, miscarriage prevention.Curing mainly high fever polydipsia, cough with lung heat, damp-heat dysentery, jaundice, heat gonorrhea spits, is defeated in battle, collapses, leaks, red eye, swell pain,
Threatened abortion, carbuncle swells furunculosis.The modern pharmacology proves that radix scutellariae has the function of antibacterium, antimycotic, antiviral, antiprotozoan.
Cape jasmine: for the dry mature fruit of madder wort cape jasmine；Containing iridoid glycosides such as Gardenoside, go hydroxyl cape jasmine
The effective components such as glycosides and mountain Cape jasmine glycosides；Nature and flavor are cold, bitter；Return heart, lung, tri-jiao channel；Effect is clearing heat-fire, removing pattogenic heat from the blood and toxic material from the body, clearing stomach gastral cavity
Blood controls pyretic epigastralgia, antipyretic strongly fragrant, row knot gas, reducing fever and causing diuresis.Cure mainly red eye, swell pain, jaundice with damp-heat pathogen, heat gonorrhea, hematuria, bleeding from five sense organs or subcutaneous tissue.It is existing
It is proved for pharmacology, cape jasmine has antipyretic-antalgic, tranquilizing soporific, anti-inflammatory, antiviral, Hepatoprotective cholagogue, improves pancreas function, adjusts
The effect of digestive system and cardio-cerebrovascular.
Fructus Forsythiae: for the fruit of Oleaceae plants Fructus Forsythiae；Containing lignanoid and its glycosides, benzyl carbinol glycosides, pentacyclic triterpene, flavones,
The effective components such as volatile oil；Nature and flavor are slightly cold, bitter；Return lung, the heart, small intestinl channel；Effect is clearing heat and detoxicating, dispersing swelling and dissipating binds, dispelling wind and heat from the body.
Cure mainly anemopyretic cold, heat toxin dysentery, heat toxin carbuncle swells, large carbuncle pyogenic infections, scrofula, urine leaching closes.The modern pharmacology proves that Fructus Forsythiae has
Resisting pathogenic microbes, antipyretic, anti-inflammatory, liver protection, town spit, antiallergy, antineoplastic action.
Fructus Aurantii: for the young fruit of rutaceae bitter orange and its congener green fruit or sweet orange etc.；Contain volatilization
Oil such as d-limonen, dextrorotation linalool, flavonoid glycoside such as neohesperidin, the effective components such as vitamin；Nature and flavor are slightly cold, bitter, sour, micro-
It is pungent；Return lung, spleen, stomach, large intestine channel；Effect is regulating the flow of QI to ease the stomach, resolving sputum disperse accumulation, promoting the circulation of qi dissipate-swelling.Cure mainly chest diaphragm feeling of fullness, the distending pain in hypochondrium,
The stagnant cough of phlegm, accumulation of food in the stomach and intes tine due to indigestion, abdominal fullness and distention, weight after rush down dysentery, intestines wind haemorrhoids, rectal prolapse, rubella itch.The modern pharmacology proves that trifoliate orange
Shell have resisting pathogenic microbes, calmness, diuresis, excited uterine smooth muscle, excited gastrointestinal smooth muscle, inhibit allergy, heart tonifying,
Boosting, the effect of cholagogue.
Radix Curcumae: for the dried root of zingiberaceous plant Radix Curcumae, Guangxi zedoary, turmeric or zedoary；Containing volatile oil such as bank alkene,
The monoterpenes such as camphor and sequiterpene, curcumin, curcumol, turmerone and starch, fat oil, weld and phellandrene etc. are effectively
Ingredient；Nature and flavor are cold, pungent, bitter；Effect is promoting blood circulation, cooling blood and hemostasis, promoting qi circulation and removing obstruction in the collateral, stasis-dispelling and pain-killing, soothing liver-gallbladder, removing jaundice.Cure mainly blood
Hot haemorrhage, pyreticosis coma, jaundice with damp-heat pathogen, stagnation of QI due to depression of the liver, swollen breasts.The modern pharmacology proves that Radix Curcumae have Hepatoprotective cholagogue,
Dissolving gall-stone adjusts hematological system, adjusts immune system, Robust speaker feature, analgesia, anti-snake venom, anti-oxidant, anti-cell canceration work
With.
Radix Angelicae Sinensis: for the root of Umbelliferae archangel Radix Angelicae Sinensis；Contain volatile oil such as phenol oil and neutral oil, a variety of organic acids
And the effective components such as a variety of inorganic elements；Nature and flavor are sweet, pungent, warm；Return liver, the heart, the spleen channel；Effect is benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, profit
Dry laxation.The all diseases of the deficiency of blood are cured mainly, irregular menstruation, menostasis, dysmenorrhea, metrorrhagia and metrostaxis, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness, intestines are dry and shit is difficult,
Dysentery with bloody stool is thick and heavy, ulcer sores, injury from falling down.The modern pharmacology proves that Radix Angelicae Sinensis has antithrombus formation, improves blood circulation, changes
Kind coronary circulation, anti-inflammatory, analgesia, antitumor, anti-oxidant, Hepatoprotective cholagogue, the effect for protecting lung and kidney.
Rhizoma Chuanxiong: for the rhizome of umbelliferae Rhizoma Chuanxiong；Contain ligustilide, chuanxingol, ligustrazine, ferulic acid, phenylacetic acid
The effective components such as methyl esters, secalin, vanillic aldehyde, cupreol, vitamin A；Nature and flavor are pungent, warm；Effect is activating microcirculation and removing stasis medicinal, promoting the circulation of qi stops
Bitterly, it dispels pathogenic wind and remove dampness.Cure mainly middle wind headache, abdominal pain, rheumatic arthralgia, treating swelling and pain by traumatic injury, sore swell and ache curative, pricking pain in the chest.Modern pharmacology
It proves, Rhizoma Chuanxiong has the function of adjusting cardiovascular system, protection kidney and liver, calmness, excited gravid uterus smooth muscle.
Radix paeoniae rubra: for the dry root of ranunculaceae plant radix paeoniae rubra or river radix paeoniae rubra；Containing in Paeoniflorin, benzoylpaeoniflorin, Chinese herbaceous peony
Ester glycosides, lacdtlorin Ⅲ, oxypaeoniflorin, Chinese herbaceous peony Ji ketone, peonin, paeonoside, paeonol, benzoic acid, cupreol, Chinese herbaceous peony
The effective components such as medicine alkali, peonol, organic acid, tannin, volatile oil, progallin A；Nature and flavor are slightly cold, bitter；Return liver, the spleen channel；
Effect is clearing heat and cooling blood, promoting blood circulation to remove blood stasis, dissipates numbness, detumescence, analgesic.Curing mainly heat, to enter ying blood, febrile virulent maculae, hematemesis and epistaxis, hot eyes swollen
Bitterly, liver-depressed hypochondrium pain, abdominal mass and abdominal pain, carbuncle swells sore pain, injury from falling down.The modern pharmacology proves that there is radix paeoniae rubra anticoagulation, anti-cardiac muscle to lack
Blood, antiatherosclerosis, anti-cerebral ischemia, inhibit immune system, resisting pathogenic microbes, antiendotoxin, liver protection, anti-inflammatory, spasmolysis,
Anti-gastric-ulcer, effect that is antitumor, adjusting central nervous system.
Radix Astragali: for leguminous plant Radix Astragali, astragalus mongolicus or other belong to the dry root of close plant；Contain polysaccharide such as Portugal
Grape sugar AG-1, AG-2 and heteroglycan AH-1, AH-2, saponins such as astragaloside I~VIII and Sayasaponin Ⅰ, Astragaloside IV and Huang
The effective components such as stilbene second glycosides；It is nature and flavor tepor, sweet；Return lung, the spleen channel；Effect is tonifying Qi and lifting yang, strengthening exterior and reducing sweat, torr sore myogenic, Li Shui
Detumescence.Cure mainly spleen-lung Qi deficiency, collapse from qi deficiency, exterior deficiency sweating, sore carbuncle difficulty burst, deficiency of vital energy and edema.The modern pharmacology proves that Radix Astragali has
Immune-enhancing effect, promote hematopoiesis function, improve gastrointestinal function, adjust heart, adjust blood pressure, it is antitumor, anti-radiation, antifatigue,
Anti-oxidative damage, liver protection effect.
Rhizoma Atractylodis Macrocephalae: for the dry rhizome of composite family rhizoma atractylodis platymiscium Rhizoma Atractylodis Macrocephalae；Contain atractylol, β-eucalyptus alcohol, hinesol, rhizoma atractylodis
The effective components such as ether, atractyloide, atractylenolqide, fructose, synanthrin；It is nature and flavor temperature, sweet, bitter；Returns spleen, stomach meridian；Effect is to mend
Spleen QI invigorating, eliminate dampness and have diuretic effect, strengthening exterior and reducing sweat, tonifying Qi miscarriage prevention.It cures mainly under splenoasthenic diarrhea, oedema, spontaneous perspiration, threatened abortion.Modern pharmacology
It proves, Rhizoma Atractylodis Macrocephalae has the effects that improve gastrointestinal function, enhancing function of immune system, antitumor, diuresis, adjusts nervous system.
Poria cocos: for the dry sclerotia of polyporaceae fungus；Contain β-pachyman, pachymaran, su-fuling, Fu
Siberian cocklebur acid, Pachymic acid, loose Siberian cocklebur acid, eburicoic acid, 3 beta-hydroxy wools load trienic acid, histidine, choline, adenine etc. effectively at
Point；Nature and flavor are flat, sweet, light；Return heart, lung, spleen, stomach, kidney channel；Effect is clearing damp and promoting diuresis, strengthening spleen and middle warmer, antitoxic heart-soothing and sedative.Cure mainly phlegm wet
Oedema, oliguria, spleen eating less, loose stool rush down under, have no peace of mind.The modern pharmacology proves that Poria cocos has Li Shui, tranquilizing the mind, anti-inflammatory suppression
Bacterium, liver protection, anti-rejection, promotes the effects of hematopoiesis function at antitumor, raising immune function.
Rhizoma alismatis: for the dry tuber of Notes On Alism At Aceae rhizoma alismatis；Containing triterpene compound such as alisol A and its acetic acid esters,
Alisol B and its acetic acid esters, alisol C, monoacetate；Sesquiterpenoids such as alisol terpene A, B, C, E；Cupreol,
The effective components such as stearic acid, glyceryl alcohol -1- hard acid rouge, melissane, choline, lectins, rhizoma alismatis polysaccharide；Nature and flavor are cold, it is sweet,
It is light；Return kidney, bladder meridian；Effect is clearing damp and promoting diuresis, rushes down kidney fire clearly.Cure mainly difficult urination, edema swelling, diarrhea due to damp-heat, stranguria with turbid discharge.It is existing
It is proved for pharmaceutical research, rhizoma alismatis has diuresis, liver protection shield kidney, inhibits kidney stone, reducing blood lipid, anti arteriosclerosis, anti-inflammatory, anti-blood
Platelet aggregation, the effect for antithrombotic, adjusting immune system, adjusting metabolism of blood glucose.
Radix Glycyrrhizae: for the dry root or rhizomes of glycyrrhizic legume or congener swollen fruit Radix and glycyrrhiza glabra etc.；Contain
There are the effective components such as triterpene saponin such as glycyrrhizin and flavonoids such as liquiritin, isoliquiritin, Neoliquiritin, isoliquiritigenin；
Nature and flavor are flat, sweet；Return heart, lung, spleen, stomach meridian；Effect is tonifying middle-Jiao and Qi, moistening lung to arrest cough, clearing heat and detoxicating, mitigation pharmacological property.Cure mainly taste
Weakness, fatigue and weakness, abdominal pain loose stool, consumptive lung disease cough and asthma, abscess of throat, sore, carbuncle and painful swelling, shortness of breath and palpitation, poisoning.Modern pharmacology card
Bright, Radix Glycyrrhizae, which has, to be seen ulcer, adjusts gastric motility, liver protection, enhance immune function, is antiviral, anti-oxidant, detoxifying, is anti-swollen
The effects of tumor, anti-arrhythmia, reducing blood lipid, protection nerve.
Provided by the present invention for preventing and treating the Chinese medicine composition of laying hen mycotoxicosis, radix scutellariae, cape jasmine, Fructus Forsythiae can clear liver
Purging fire for removing toxin, Fructus Aurantii, Radix Curcumae are good at harmonizing the functional activities of vital QI, dredge cholagogue road, Radix Angelicae Sinensis, Rhizoma Chuanxiong radix paeoniae rubra detumescence, nourishing blood and liver, Radix Astragali,
Rhizoma Atractylodis Macrocephalae, Poria cocos, rhizoma alismatis invigorating the spleen and stomach, dehumidifying row saliva, Radix Glycyrrhizae coordinating the drug actions of a prescription.Chu's medicine collaboration, have clear liver removing toxic substances, dredge it is strongly fragrant it is diathermanous,
Blood stasis dispersing and deswelling, the promoting flow of qi and blood circulation, Hang Jin, qi-restoratives effect can play anti-inflammatory, antiallergy, antitoxin, antibacterial, antiviral, enhancing body
The effects of immunity.
It is injured for bodies such as lesions of liver and kidney caused by mycotoxin, there is above-mentioned Chinese medicine composition certain reparation to make
With can be improved laying hen immunity of organisms and hepatic and renal function, promote degradation and tolerance of the body to mycotoxin, mitigate mould
Harm of the toxin to laying hen, improves the production performance of laying hen.
From simplified dosage of each component, control efficiency of mycotoxin etc. is comprehensively considered, it is preferred that above-mentioned Chinese medicine group
It closes object to be made of the raw material of following parts by weight: 20 parts of radix scutellariae, 20 parts of cape jasmine, 60 parts of Fructus Forsythiae, 50 parts of Fructus Aurantii, 60 parts of Radix Curcumae, Radix Angelicae Sinensis
60 parts, 40 parts of Rhizoma Chuanxiong, 40 parts of radix paeoniae rubra, 60 parts of Radix Astragali, 60 parts of Rhizoma Atractylodis Macrocephalae, 60 parts of rhizoma alismatis, 80 parts of Poria cocos, 40 parts of Radix Glycyrrhizae.
It is a kind of for preventing and treating the Chinese medicine microecological preparation of laying hen mycotoxicosis, by fermenting microbe and following parts by weight
Raw material is made: 15~25 parts of radix scutellariae, 15~25 parts of cape jasmine, 55~65 parts of Fructus Forsythiae, 45~55 parts of Fructus Aurantii, 55~65 parts of Radix Curcumae, when
Return 55~65 parts, 35~45 parts of Rhizoma Chuanxiong, 35~45 parts of radix paeoniae rubra, 55~65 parts of Radix Astragali, 55~65 parts of Rhizoma Atractylodis Macrocephalae, 55~65 parts of rhizoma alismatis,
75~85 parts of Poria cocos, 35~45 parts of Radix Glycyrrhizae.
The Chinese medicine microecological preparation for being used to prevent and treat laying hen mycotoxicosis of the invention, by fermenting microbe and to mould poison
There is the Chinese medicine composition of preventive and therapeutic effect to be made for element poisoning, and utilization rate and drug effect can be improved after probiotics fermention in traditional Chinese medicine ingredients,
Reduce dosage.
Be to improve to the degradation of mycotoxin, optimize the fermentation to Chinese medicine, it is preferred that the fermenting microbe by
Bacillus subtilis strain, Bacillus licheniformis strain, lactobacillus plantarum strain, S. cervisiae strain composition.It is further excellent
Choosing, every 15~25g radix scutellariae is corresponding to be added 70~80mL of Bacillus subtilis strain, 70~80mL of bacillus licheniformis, plant
45~55mL of lactobacillus strain, 90~110mL of S. cervisiae strain.
The Chinese medicine composition is made of the raw material of following parts by weight: 20 parts of radix scutellariae, 20 parts of cape jasmine, 60 parts of Fructus Forsythiae, Fructus Aurantii
50 parts, 60 parts of Radix Curcumae, 60 parts of Radix Angelicae Sinensis, 40 parts of Rhizoma Chuanxiong, 40 parts of radix paeoniae rubra, 60 parts of Radix Astragali, 60 parts of Rhizoma Atractylodis Macrocephalae, 60 parts of rhizoma alismatis, 80 parts of Poria cocos,
40 parts of Radix Glycyrrhizae.It is furthermore preferred that every 20g radix scutellariae is corresponding to be added Bacillus subtilis strain 75mL, bacillus licheniformis 75mL, plant
Lactobacillus strain 50mL, S. cervisiae strain 100mL.
The viable count of the Bacillus subtilis strain is (2.0~3.0) × 109CFU/mL, Bacillus licheniformis strain
Viable count be (2.0~3.0) × 109CFU/mL, the viable count of lactobacillus plantarum strain are (1.0~10.0) × 108CFU/
ML, the viable count of saccharomyces cerevisiae strain are (1.0~5.0) × 108CFU/mL.Preferably, the Bacillus subtilis strain
Viable count is 3.0 × 109CFU/mL, the viable count of Bacillus licheniformis strain are 2.0 × 109CFU/mL, lactobacillus plantarum strain
Viable count be 5.0 × 108CFU/mL, the viable count of saccharomyces cerevisiae strain are 4.0 × 108CFU/mL。
The characteristic of bacillus subtilis, bacillus licheniformis, lactobacillus plantarum, S. cervisiae is illustrated below:
Bacillus subtilis: for Bacillaceae bacillus, strict aerobes, culture forms cream on nutrient agar
White or yellowish round or irregular, rough surface, opaque bacterium colony, bacterium solution after cultivating 10 hours on liquid medium within
Mycoderm is commonly formed in muddiness；Its resistance is strong, not stringent to growth and breeding condition.Major function is to improve efficiency of feed utilization, improve
Animal disease resistant power, enhancing animal body fluid immune function, improvement barn environment health etc..Meanwhile bacillus subtilis energy output one
A little biology enzymes, there is certain effect to degrading mold toxin.
Bacillus licheniformis: widely distributed for the gram-positive bacterium in bacillus；There is gemma, gemma is in ellipse
It is round or cylindrical；Growth temperature is 15~58 DEG C, and pH is generally 6.8~8.0, can be by acetyl first within the scope of certain pH
Base Reduction of methanol is at substances such as nitrate；Can generate a variety of antibacterial materials in the metabolic process, and have very strong protease and
Amylase activity.Major function is to adjust microbial population of animal intestinal tract balance, enhancing immunity of organism, the digestion and absorption for promoting nutrient, together
When play degrading mold toxin certain effect.
Lactobacillus plantarum: for the lactobacillus in Lactobacillaceae, amphimicrobian, optimal pH 6.5；Strain in rod-short or
Chain does not produce gemma, is in canescence, circle, smooth, opaque bacterium colony in LBS agar medium；It is only produced in fermentation process
Lactogenesis acid, fermentable carbohydrates it is very capable.Major function is to maintain intestinal flora balance and function of intestinal canal, promotes nutrition
The absorption of substance improves immune level, antibacterial, antitumor, reduction cholesterol, improvement liver function etc..
S. cervisiae: it is widely distributed for the unicellular microorganism of Mycophyta, there is cell wall, form is because of kinds of culture medium
With incubation time length and it is different, have round, oval, oval etc., usually based on budding breeding, and fast speed；It can divide
Carbohydrate is solved, alcoholic content is generated.Major function is to improve product special flavour, and have additional nutrients value, improves digestive function etc..
Meanwhile yeast cell wall energy absorbing mycotoxin, it plays a role to the harm for reducing mycotoxin.
In the present invention, the organic assembling of the above fermenting microbe is selected to ferment Chinese medicine, on the one hand can played to mould
The degradation of toxin reduces toxic action of the toxin to body；On the other hand by the fermentation to Chinese medicine, Chinese medicine is improved
Curative effect, reduce dosage.
The Chinese medicine microecological preparation for being used to prevent laying hen mycotoxicosis of the invention, passes through and improves the organs function such as liver
Can and drug effect be played to the direct degradation of mycotoxin, mitigates harm of the mycotoxin to laying hen, improve the production of laying hen
Performance.
Chinese medicine microecological preparation of the invention is with effect following prominent: first, improve laying hen immunity of organisms and liver
Function improves body to the tolerance of mycotoxin；Second, the probiotic ingredient in preparation plays degradation in body enteron aisle and raises
The effect of mycotoxin in material mitigates harm of the toxin to body；Third, traditional Chinese medicine ingredients are after probiotics fermention, utilization rate
It is improved with drug effect；4th, the problems such as capable of reducing the application of antibiotic, making bacterial drug resistance, medicament residue, is readily solved；Most
Afterwards, immunity of layer chicken and enteron aisle digestion and absorption function are enhanced, so that its body is in health status, and then improve laying rate of laying hen
And the quality of egg, postpone to eliminate the time.Reach raising performance in layers on the whole, creates economic value for breeding layer chicken industry
Purpose.
It is a kind of for preventing and treating the preparation method of the Chinese medicine microecological preparation of laying hen mycotoxicosis, comprising the following steps:
Take formula ratio raw material and fermenting microbe mixing after, under the conditions of 25~35 DEG C 5~15d of sealed fermenting to get.
Preferably, the raw material is powder, is made by each bulk pharmaceutical chemicals grinding and sieving.The screen size of sieve used in being sieved
For 60~120 mesh, further preferably 80 mesh.
Preferably, fermentation condition is 32 DEG C of sealed fermenting 12d.
It is of the invention for preventing and treating the preparation method of the Chinese medicine microecological preparation of laying hen mycotoxicosis, be by Chinese medicine with
It is made after fermenting microbe mixing through solid state fermentation；This method is easy to operate, without the harmful substances such as three industrial wastes, utilization rate after fermentation
Height, feasibility is good, is suitable for large-scale industrial production, has good promotion and application value.
The usage of Chinese medicine microecological preparation for preventing and treating laying hen mycotoxicosis of the invention are as follows: in layer breeding
Whole process, feed addition this product 3kg per ton use 15~20d every time, are spaced 10d medication again, according to this repeatedly, until laying hen is eliminated.
Specific embodiment
Embodiments of the present invention are described further combined with specific embodiments below.
Embodiment 1
The Chinese medicine composition for being used to prevent and treat laying hen mycotoxicosis of the present embodiment, is made of the raw material of following weight:
Radix scutellariae 20g, cape jasmine 20g, Fructus Forsythiae 60g, Fructus Aurantii 50g, Radix Curcumae 60g, Radix Angelicae Sinensis 60g, Rhizoma Chuanxiong 40g, radix paeoniae rubra 40g, Radix Astragali 60g, Rhizoma Atractylodis Macrocephalae
60g, rhizoma alismatis 60g, Poria cocos 80g, Radix Glycyrrhizae 40g.
The Chinese medicine composition of the present embodiment smashes it through 80 meshes in the preparation, by each raw material, is uniformly mixed to obtain the final product.
Embodiment 2
The Chinese medicine microecological preparation for being used to prevent and treat laying hen mycotoxicosis of the present embodiment, by the Chinese medicine group of embodiment 1
It closes object and fermenting microbe is made, fermenting microbe is by Bacillus subtilis strain, Bacillus licheniformis strain, lactobacillus plantarum bacterium
Kind, S. cervisiae strain composition, the dosage that every 20g radix scutellariae corresponds to the above strain is respectively 75mL, 75mL, 50mL, 100mL.
Wherein, the viable count of Bacillus subtilis strain is 3.0 × 109CFU/mL, the viable count of Bacillus licheniformis strain is 2.0 ×
109CFU/mL, the viable count of lactobacillus plantarum strain are 5.0 × 108CFU/mL, the viable count of saccharomyces cerevisiae strain is 4.0 ×
108CFU/mL。
The preparation method of the Chinese medicine microecological preparation for preventing and treating laying hen mycotoxicosis of the present embodiment, use are following
Step: crossing 80 meshes after traditional Chinese medicine powder is broken into, mixes by formula ratio and fermenting microbe, later the sealed fermenting 12d at 32 DEG C
To obtain the final product.
Embodiment 3
The Chinese medicine microecological preparation for being used to prevent and treat laying hen mycotoxicosis of the present embodiment, by fermenting microbe and Chinese medicine group
Object composition is closed, Chinese medicine composition is made of the raw material of following weight: radix scutellariae 15g, cape jasmine 15g, Fructus Forsythiae 55g, Fructus Aurantii 45g, Radix Curcumae
55g, Radix Angelicae Sinensis 55g, Rhizoma Chuanxiong 35g, radix paeoniae rubra 35g, Radix Astragali 55g, Rhizoma Atractylodis Macrocephalae 55g, rhizoma alismatis 55g, Poria cocos 75g, Radix Glycyrrhizae 35g.
Fermenting microbe is by Bacillus subtilis strain, Bacillus licheniformis strain, lactobacillus plantarum strain, S. cervisiae
Strain composition, the dosage that every 20g radix scutellariae corresponds to the above strain is respectively 70mL, 70mL, 45mL, 90mL.Wherein, bacillus subtilis
The viable count of bacterium strain is 3.0 × 109CFU/mL, the viable count of Bacillus licheniformis strain are 3.0 × 109CFU/mL, plant cream
The viable count of bacillus species is 1.0 × 109CFU/mL, the viable count of saccharomyces cerevisiae strain are 5.0 × 108CFU/mL。
The preparation method of the Chinese medicine microecological preparation for preventing and treating laying hen mycotoxicosis of the present embodiment, use are following
Step: crossing 80 meshes after traditional Chinese medicine powder is broken into, mixes by formula ratio and fermenting microbe, later sealed fermenting under the conditions of 25 DEG C
15d to obtain the final product.
Embodiment 4
The Chinese medicine microecological preparation for being used to prevent and treat laying hen mycotoxicosis of the present embodiment, by fermenting microbe and Chinese medicine group
Object composition is closed, Chinese medicine composition is made of the raw material of following weight: radix scutellariae 25g, cape jasmine 25g, Fructus Forsythiae 65g, Fructus Aurantii 55g, Radix Curcumae
65g, Radix Angelicae Sinensis 65g, Rhizoma Chuanxiong 45g, radix paeoniae rubra 45g, Radix Astragali 65g, Rhizoma Atractylodis Macrocephalae 65g, rhizoma alismatis 65g, Poria cocos 85g, Radix Glycyrrhizae 45g.
Fermenting microbe is by Bacillus subtilis strain, Bacillus licheniformis strain, lactobacillus plantarum strain, S. cervisiae
Strain composition, the dosage that every 20g radix scutellariae corresponds to the above strain is respectively 80mL, 80mL, 55mL, 110mL.Wherein, withered grass gemma
The viable count of bacillus species is 2.0 × 109CFU/mL, the viable count of Bacillus licheniformis strain are 2.0 × 109CFU/mL, plant
The viable count of lactobacillus strain is 1.0 × 108CFU/mL, the viable count of saccharomyces cerevisiae strain are 1.0 × 108CFU/mL。
The preparation method of the Chinese medicine microecological preparation for preventing and treating laying hen mycotoxicosis of the present embodiment, use are following
Step: crossing 60 meshes after traditional Chinese medicine powder is broken into, mixes by formula ratio and fermenting microbe, later sealed fermenting under the conditions of 35 DEG C
5d to obtain the final product.
Embodiment 5
The Chinese medicine microecological preparation for being used to prevent and treat laying hen mycotoxicosis of the present embodiment, by fermenting microbe and Chinese medicine group
Object composition is closed, Chinese medicine composition is made of the raw material of following weight: radix scutellariae 15g, cape jasmine 15g, Fructus Forsythiae 55g, Fructus Aurantii 45g, Radix Curcumae
55g, Radix Angelicae Sinensis 65g, Rhizoma Chuanxiong 45g, radix paeoniae rubra 45g, Radix Astragali 55g, Rhizoma Atractylodis Macrocephalae 55g, rhizoma alismatis 55g, Poria cocos 75g, Radix Glycyrrhizae 35g.
Fermenting microbe is by Bacillus subtilis strain, Bacillus licheniformis strain, lactobacillus plantarum strain, S. cervisiae
Strain composition, the dosage that every 20g radix scutellariae corresponds to the above strain is respectively 70mL, 80mL, 50mL, 100mL.Wherein, withered grass gemma
The viable count of bacillus species is 2.0 × 109CFU/mL, the viable count of Bacillus licheniformis strain are 3.0 × 109CFU/mL, plant
The viable count of lactobacillus strain is 8.0 × 108CFU/mL, the viable count of saccharomyces cerevisiae strain are 3.0 × 108CFU/mL。
The preparation method of the Chinese medicine microecological preparation for preventing and treating laying hen mycotoxicosis of the present embodiment, use are following
Step: sieving with 100 mesh sieve after traditional Chinese medicine powder is broken into, and mixes by formula ratio and fermenting microbe, later closed hair under the conditions of 30 DEG C
Ferment 15d to obtain the final product.
Embodiment 6
The Chinese medicine microecological preparation for being used to prevent and treat laying hen mycotoxicosis of the present embodiment, by fermenting microbe and Chinese medicine group
Object composition is closed, Chinese medicine composition is made of the raw material of following weight: radix scutellariae 25g, cape jasmine 25g, Fructus Forsythiae 65g, Fructus Aurantii 55g, Radix Curcumae
65g, Radix Angelicae Sinensis 55g, Rhizoma Chuanxiong 35g, radix paeoniae rubra 35g, Radix Astragali 65g, Rhizoma Atractylodis Macrocephalae 65g, rhizoma alismatis 65g, Poria cocos 85g, Radix Glycyrrhizae 45g.
Fermenting microbe is by Bacillus subtilis strain, Bacillus licheniformis strain, lactobacillus plantarum strain, S. cervisiae
Strain composition, the dosage that every 20g radix scutellariae corresponds to the above strain is respectively 80mL, 70mL, 45mL, 110mL.Wherein, withered grass gemma
The viable count of bacillus species is 3.0 × 109CFU/mL, the viable count of Bacillus licheniformis strain are 2.0 × 109CFU/mL, plant
The viable count of lactobacillus strain is 3.0 × 108CFU/mL, the viable count of saccharomyces cerevisiae strain are 5.0 × 108CFU/mL。
The preparation method of the Chinese medicine microecological preparation for preventing and treating laying hen mycotoxicosis of the present embodiment, use are following
Step: crossing 120 meshes after traditional Chinese medicine powder is broken into, mixes by formula ratio and fermenting microbe, later closed hair under the conditions of 28 DEG C
Ferment 7d to obtain the final product.
Following tests example is resulting to embodiment 1-6 for preventing and treating the Chinese medicine composition and Chinese medicine of laying hen mycotoxicosis
Prevention and treatment performance of the probiotics in laying hen feeds is detected, in the whole process of layer breeding, feed addition this product per ton
3kg uses 17d every time, is spaced 10d medication again, according to this repeatedly, until laying hen is eliminated.
Test example 1
2016 in Hebei province Xingtai City laying hen, the brown laying hen sudden onset of 52 week old Luo Man, feed intake decline, spirit
State is deteriorated, and laying rate declines 20%-30%, and eggshell increases without color, broken egg, soft egg.It is inquired, the feed fed exists
Dampness mildew situation, is diagnosed as chicken mycotoxicosis in conjunction with the clinical symptoms and dissect result of diseased chicken.Randomly select 700 diseases
Chicken is divided into 7 groups, every group 100, group 1-6 according to embodiment 1-6 usage successively the Chinese medicine composition of feeding 1-6 containing embodiment and
Chinese medicine microecological preparation.Group 7 is blank group, not any drug of feeding.The egg laying performance that laying hen is recorded after 1 week, continuously records 1
In week, the results are shown in Table 1.
The Chinese medicine composition of each embodiment of table 1 or the feeding effect of Chinese medicine microecological preparation
(note: laying rate raising value, day consumption amount raising value and feedstuff-egg ratio decreasing value are respectively the laying rate of group 1-6, day consumption
The laying rate of doses and feedstuff-egg ratio and group 7, the absolute value of the difference of daily material consumption and feedstuff-egg ratio.)
It can be seen from the result of table 1 compared to the blank group, the Chinese medicine composition of embodiment 1 is to prevention and treatment laying hen mould poison
Element poisoning has good effect, and the indexs such as laying rate, daily material consumption, average egg weight, feedstuff-egg ratio are obviously improved, and takes reality
After the Chinese medicine microecological preparation for applying a 2-6, the indexs such as laying rate, daily material consumption, average egg weight, feedstuff-egg ratio obtain further excellent
Change, laying rate of laying hen improves 15.60-17.12%, and daily material consumption improves 16.61-17.51g, and feedstuff-egg ratio reduces 0.30-
0.39%.Test result shows Chinese medicine composition and Chinese medicine microecological preparation of the invention in treatment because mycotoxicosis is made
At Layer Production Performance decline aspect have remarkable result.
Typical case 1:2016 compares test in Xinzheng City, Henan Province laying hen, and 8000 65 weeks seas are blue brown
Laying hen is randomly divided into 2 groups, respectively test group and control group, and every group 4000, test group feeds the micro- life of Chinese medicine containing embodiment 6
The feed of state preparation is fed by method shown in embodiment 6；Control group feeding Normal Goods feed, feeding management is by field
It arranges to carry out.The egg laying performance of laying hen, continuous record 1 week are recorded after 1 week.As a result as follows, the average egg production and egg of test group
It is respectively again 87.62%, 60.17g, the average egg production and egg size of control group are respectively 76.57%, 57.34g.With control group
It compares, 11.05%, 2.83g has been respectively increased in the average egg production and egg size of test group.
Test example 2
2017 in Shandong Province Tai'an laying hen, the 60 laying hen sudden onset of week old agricultural university three, feed intake decline, essence
Refreshing state is deteriorated, and laying rate declines 20%-25%, and lopsided egg quantity increases.Dissection discovery diseased chicken liver kidney occurs in various degree
Damage, ovary and fallopian tubal atrophy.It is chicken mycotoxicosis through Disease Diagnosis of Veterinary.It randomly selects 700 diseased chickens and is divided into 7 groups, often
Group 100, group 1-6 according to usage successively feeding 1-6 containing embodiment of embodiment 1-6 Chinese medicine composition and Traditional Chinese drug microecology system
Agent.Group 7 is blank group, not any drug of feeding.The index of quality of laying hen, continuous record 2 weeks, as a result such as 2 institute of table are recorded after 1 week
Show.
2 each group laying hen Egg Quality Contrast on effect of table
(note: it is each test group relative to blank that yolk, which brings up again high level, eggshell strength raising value, shell thickness raising value,
Group calculates gained.)
As shown in Table 2, it is compared with blank group, after the Chinese medicine composition for feeding embodiment 1, the produced egg of laying hen
The indexs such as yolk weight, eggshell strength, shell thickness have clear improvement, after the Chinese medicine microecological preparation for feeding embodiment 2, egg
Above-mentioned performance advanced optimized, yolk brings up again high level and reaches 19.41-22.22%, and eggshell strength raising value reaches
13.94-19.23%, shell thickness raising value reach 6.67-13.33%.
Typical case 2:2016 is in Gushi County of Henan Province county chicken house, 45 week old or so chicken group's sudden onset, laying rate from
75% or so falls to approximately 40%, and lopsided egg quantity increases, and full group chicken spirit is depressed, feed intake decline, through understanding the state of an illness, reason
The reasons such as predominantly consecutive numbers daily rain amount, causes corn to go mouldy, and chicken coop air circulation is unsmooth cause chicken house to fall ill.Using reality
The Chinese medicine microecological preparation of example 4 is applied, 3d is used in conjunction in feed addition 4kg per ton, and full group chicken spirit improves, and feed intake increases, and produces after 7d
Egg rate is restored to before the onset, about 75%, egg size average out to 53g.
Claims (9)
1. a kind of Chinese medicine composition for preventing and treating laying hen mycotoxicosis, which is characterized in that be made of the raw material of following parts by weight:
15~25 parts of radix scutellariae, 15~25 parts of cape jasmine, 55~65 parts of Fructus Forsythiae, 45~55 parts of Fructus Aurantii, 55~65 parts of Radix Curcumae, Radix Angelicae Sinensis 55~65
Part, 35~45 parts of Rhizoma Chuanxiong, 35~45 parts of radix paeoniae rubra, 55~65 parts of Radix Astragali, 55~65 parts of Rhizoma Atractylodis Macrocephalae, 55~65 parts of rhizoma alismatis, Poria cocos 75~
85 parts, 35~45 parts of Radix Glycyrrhizae.
2. the Chinese medicine composition of prevention and treatment laying hen mycotoxicosis as described in claim 1, which is characterized in that by following weight
Part raw material composition: 20 parts of radix scutellariae, 20 parts of cape jasmine, 60 parts of Fructus Forsythiae, 50 parts of Fructus Aurantii, 60 parts of Radix Curcumae, 60 parts of Radix Angelicae Sinensis, 40 parts of Rhizoma Chuanxiong,
40 parts of radix paeoniae rubra, 60 parts of Radix Astragali, 60 parts of Rhizoma Atractylodis Macrocephalae, 60 parts of rhizoma alismatis, 80 parts of Poria cocos, 40 parts of Radix Glycyrrhizae.
3. a kind of for preventing and treating the Chinese medicine microecological preparation of laying hen mycotoxicosis, which is characterized in that by fermenting microbe and with
The raw material of lower parts by weight is made: 15~25 parts of radix scutellariae, 15~25 parts of cape jasmine, 55~65 parts of Fructus Forsythiae, 45~55 parts of Fructus Aurantii, Radix Curcumae 55
~65 parts, 55~65 parts of Radix Angelicae Sinensis, 35~45 parts of Rhizoma Chuanxiong, 35~45 parts of radix paeoniae rubra, 55~65 parts of Radix Astragali, 55~65 parts of Rhizoma Atractylodis Macrocephalae, rhizoma alismatis
55~65 parts, 75~85 parts of Poria cocos, 35~45 parts of Radix Glycyrrhizae.
4. as claimed in claim 3 for preventing and treating the Chinese medicine microecological preparation of laying hen mycotoxicosis, which is characterized in that institute
Fermenting microbe is stated by Bacillus subtilis strain, Bacillus licheniformis strain, lactobacillus plantarum strain, S. cervisiae strain group
At.
5. as claimed in claim 4 for preventing and treating the Chinese medicine microecological preparation of laying hen mycotoxicosis, which is characterized in that every
15~25g radix scutellariae is corresponding to be added 70~80mL of Bacillus subtilis strain, 70~80mL of Bacillus licheniformis strain, plant cream bar
45~55mL of bacterium strain, 90~110mL of S. cervisiae strain.
6. as claimed in claim 3 for preventing and treating the Chinese medicine microecological preparation of laying hen mycotoxicosis, which is characterized in that by
Fermenting microbe and the raw material of following parts by weight are made: 20 parts of radix scutellariae, 20 parts of cape jasmine, 60 parts of Fructus Forsythiae, 50 parts of Fructus Aurantii, 60 parts of Radix Curcumae,
60 parts of Radix Angelicae Sinensis, 40 parts of Rhizoma Chuanxiong, 40 parts of radix paeoniae rubra, 60 parts of Radix Astragali, 60 parts of Rhizoma Atractylodis Macrocephalae, 60 parts of rhizoma alismatis, 80 parts of Poria cocos, 40 parts of Radix Glycyrrhizae.
7. as claimed in claim 6 for preventing and treating the Chinese medicine microecological preparation of laying hen mycotoxicosis, which is characterized in that every
20g radix scutellariae is corresponding be added Bacillus subtilis strain 75mL, Bacillus licheniformis strain 75mL, lactobacillus plantarum strain 50mL,
S. cervisiae strain 100mL.
8. the Chinese medicine microecological preparation for being used to prevent and treat laying hen mycotoxicosis as described in claim 4 or 5 or 7, feature
It is, the viable count of the Bacillus subtilis strain is (2.0~3.0) × 109CFU/mL, the work of Bacillus licheniformis strain
Bacterium number is (2.0~3.0) × 109CFU/mL, the viable count of lactobacillus plantarum strain are (1.0~10.0) × 108CFU/mL makes
The viable count of brewer yeast strain is (1.0~5.0) × 108CFU/mL。
9. a kind of as claimed in claim 3 for preventing and treating the preparation side of the Chinese medicine microecological preparation of laying hen mycotoxicosis
Method, which comprises the following steps: close under the conditions of 25~35 DEG C after taking raw material and the fermenting microbe mixing of formula ratio
Close 5~15d of fermentation to get.
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| CN112553115A (en) * | 2020-12-23 | 2021-03-26 | 南昌大学 | Application of lactobacillus plantarum ZDY2013 in preparation of products for relieving kidney injury |
| CN113577222A (en) * | 2021-08-02 | 2021-11-02 | 四川成邦药业有限公司 | Traditional Chinese medicine fermentation product for treating animal mould poisoning and preparation method and system thereof |
| NL2032797B1 (en) * | 2022-08-18 | 2024-03-04 | Univ Northwest Minzu | Application of glycyrrhiza uralensis and lactic acid bacteria in preventing and/or alleviating damage of moldy feeds and additive thereof |
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| CN1325692A (en) * | 2000-05-26 | 2001-12-12 | 姜伟 | Medicine with quantitative antiendotoxic action |
| CN103655794A (en) * | 2012-08-31 | 2014-03-26 | 武汉蜀泰科技有限公司 | Medicine for treating aflatoxin poisoning |
| CN102846674B (en) * | 2012-08-31 | 2014-06-11 | 郑州后羿制药有限公司 | Traditional Chinese drug microecology composition and preparation method thereof |
| CN105724772A (en) * | 2016-02-24 | 2016-07-06 | 济南亿民动物药业有限公司 | Chinese herbal medicine micro-ecological compound feed additive and preparation and use method thereof |
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| CN112553115A (en) * | 2020-12-23 | 2021-03-26 | 南昌大学 | Application of lactobacillus plantarum ZDY2013 in preparation of products for relieving kidney injury |
| CN113577222A (en) * | 2021-08-02 | 2021-11-02 | 四川成邦药业有限公司 | Traditional Chinese medicine fermentation product for treating animal mould poisoning and preparation method and system thereof |
| NL2032797B1 (en) * | 2022-08-18 | 2024-03-04 | Univ Northwest Minzu | Application of glycyrrhiza uralensis and lactic acid bacteria in preventing and/or alleviating damage of moldy feeds and additive thereof |
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