CN110522673B

CN110522673B - Oral care composition

Info

Publication number: CN110522673B
Application number: CN201910864334.6A
Authority: CN
Inventors: 叶德成; 高琳; 陈晓斌
Original assignee: Hawley & Hazel Bvi Co ltd
Current assignee: Hawley & Hazel Bvi Co ltd
Priority date: 2019-09-12
Filing date: 2019-09-12
Publication date: 2022-05-27
Anticipated expiration: 2039-09-12
Also published as: CN110522673A

Abstract

The present invention relates to an oral care composition comprising: a) baking soda, b) an anionic surfactant, c) a cationic or amphoteric surfactant, d) coconut oil, and e) an orally acceptable carrier. The oral care composition not only has abundant foam amount, but also has foam density which can meet the taste requirement of consumers.

Description

Oral care composition

Technical Field

The invention relates to the technical field of oral care, in particular to an oral care composition.

Background

The foaming mouthfeel is one of the main sensory components of oral care products (such as toothpaste and the like). In china, consumers have a higher demand for toothpaste foam than they do abroad, and consumers often associate foam with tooth cleaning. At present, the research on the toothpaste foam is mainly focused on the foam quantity, the detection method of the foam quantity is a classical Roche foam detection method, and the national standard GB 8372 of the toothpaste has the requirement on the foam quantity of the toothpaste. Along with the continuous improvement of the sensory experience requirements of consumers on toothpaste, the importance of the toothpaste foam evaluation index is gradually improved. Foam density is a concept already used in the cosmetics industry, and descriptions of Creamy, mousse, etc. are also attracting increasing consumer attention. In the oral care industry, consumers are generally required to characterize the density of foam by mixing the characteristics of the size of the foam, the smoothness of the foam, the thickness of the foam, and the like. A thick foam should be fine, smooth and thick. In contrast, a thick, breakable, thin foam does not create a pleasant experience.

In oral care compositions, baking soda is commonly used as an abrasive to clean teeth with lower abrasion values than other abrasives. However, baking soda has defoaming property, so that the formula cannot meet the requirement of consumers on abundant foam of products.

Chinese patent application No. 201680030731.8, entitled "foaming dentifrice with desensitizing agent" discloses an oral care composition. The document mentions: the dual surfactant system without nonionic surfactant, with the surfactants being anionic and cationic/amphoteric surfactants, produces improved foaming characteristics in artificial saliva, and also compensates for the defoaming properties of saliva. However, the composition has the following disadvantages: the dual surfactant system can improve the amount of foam, but has little effect on improving the density of the foam.

Disclosure of Invention

The technical problem to be solved by the invention is to provide an oral care composition. The oral care composition has abundant foam amount, and the foam density can meet the taste requirement of consumers.

In order to solve the technical problems, the invention adopts the following technical scheme:

an oral care composition comprising

a) Baking soda

b) An anionic surfactant, a surfactant,

c) a cationic or amphoteric surfactant, and a surfactant,

d) coconut oil, and

e) an orally acceptable carrier.

Preferably, the oral care composition further comprises silica, present as an abrasive.

Preferably, the anionic surfactant is sodium lauryl sulfate.

Preferably, the cationic or amphoteric surfactant is cocamidopropyl betaine.

Preferably, the anionic surfactant is present in the oral care composition in a mass ratio of 1.5 to 2.5%.

Preferably, the cationic or amphoteric surfactant is present in the oral care composition in a mass ratio of from 0.5 to 1.5%.

Preferably, the coconut oil is present in the oral care composition at a level of 0.1 to 1.2% by weight.

Preferably, the oral care composition further comprises other abrasives including, but not limited to, one or more of calcium carbonate, calcium phosphate, calcium hydrogen phosphate.

Preferably, the oral care composition comprises a toothpaste, gel, or tooth powder.

Any range recited herein is intended to include the endpoints and any number between the endpoints and any subrange subsumed therein or defined therein.

The starting materials of the present invention are commercially available, unless otherwise specified, and the equipment used in the present invention may be any equipment conventionally used in the art or may be any equipment known in the art.

Compared with the prior art, the invention has the following beneficial effects:

the oral care composition has abundant foam quantity, and the foam density meets the taste requirement of consumers. That is, the present invention improves the substantial decrease in the amount of foam and the foam density caused by the addition of baking soda by adding coconut oil to the oral care composition.

Detailed Description

In order to more clearly illustrate the invention, the invention is further described below in connection with preferred embodiments. It is to be understood by persons skilled in the art that the following detailed description is illustrative and not restrictive, and is not to be taken as limiting the scope of the invention.

As one aspect of the present invention, an oral care composition of the present invention comprises

a) Baking soda

b) An anionic surfactant, a surfactant,

c) a cationic or amphoteric surfactant, and a surfactant,

d) coconut oil, and

e) an orally acceptable carrier.

It has been unexpectedly found that in oral care compositions, baking soda is commonly used as an abrasive to clean teeth with lower abrasion values than other abrasives. However, because baking soda has defoaming property, although the foam quantity and foam density can be increased by adding a dual surfactant system, the foam density still does not meet the requirement of a user, and the foam density of the oral care composition can be obviously increased by adding coconut oil.

In certain embodiments of the present invention, the oral care composition further comprises silica, present as an abrasive. Applicants have found that when abrasives are added, such as silica, calcium carbonate, etc., the amount of foam and foam density is optimal with the addition of silica.

In certain embodiments of the present invention, the anionic surfactant is sodium lauryl sulfate.

In certain embodiments of the invention, the cationic or amphoteric surfactant is cocamidopropyl betaine.

In certain embodiments of the present invention, the anionic surfactant is present in the oral care composition at a mass ratio of 1.5 to 2.5%, preferably 1.8 to 2.3%, preferably 2.0 to 2.2%.

In certain embodiments of the present invention, the cationic or amphoteric surfactant is present in the oral care composition in a mass ratio of from 0.5 to 1.5%, preferably from 0.8 to 1.2%.

In certain embodiments of the invention, the coconut oil is present in the oral care composition at a mass ratio of 0.1 to 1.2%, or 0.1 to 1.0%, or 0.1 to 0.8%, or 0.1 to 0.6%, or 0.1 to 0.4%, or 0.3 to 1.2%, or 0.3 to 1.0%, or 0.3 to 0.8%, or 0.3 to 0.6%, or 0.5 to 1.2%, or 0.5 to 1.0%, or 0.5 to 0.8%, or 0.7 to 1.2%, or 0.7 to 1.0%, or 0.9 to 1.2%.

In certain embodiments of the present invention, the oral care composition further comprises other abrasives including, but not limited to, calcium carbonate, calcium phosphate, calcium hydrogen phosphate.

In certain embodiments of the present invention, the oral care composition comprises a toothpaste, gel, or dentifrice.

In the present invention, the "orally acceptable carrier" refers to any vehicle suitable for formulating the oral care compositions disclosed herein; (ii) is not harmful to the mammal when the orally acceptable carrier is retained in the mouth in the amounts disclosed herein without swallowing for a period of time sufficient to allow effective contact with the tooth surface as required by the present invention; overall, an orally acceptable carrier is not harmful if not intentionally swallowed; suitable orally acceptable carriers include, for example, one or more of the following: water, thickeners, buffers, humectants, surfactants, sweetening agents, flavoring agents, visual aids (e.g., pigments, dyes, or mixtures thereof), anti-caries agents, antibacterial agents, whitening agents, desensitizing agents, vitamins, preservatives, enzymes, mixtures thereof, and the like.

In certain preferred embodiments of the present invention, adjuvants such as humectants and/or thickeners are included in the oral care composition.

"humectants" are ingredients that prevent the oral care composition from becoming dehydrated and hardened. Exemplary humectants include, but are not limited to, glycerin, propylene glycol, sorbitol, and the like. The humectant is typically present in the oral care composition in an amount of 10 to 80% by mass.

A "thickener" is a substance that increases the viscosity of a solution or liquid/solid mixture, but does not substantially change its properties. The purpose of the thickener is to provide skeleton, flow and stability to the product. Exemplary thickening agents include, but are not limited to, one or more of hydroxyethylcellulose, carboxymethylcellulose and salts thereof (e.g., sodium carboxymethylcellulose), carrageenan (carrageenan), carboxyvinyl polymers, xanthan gum (xanthang μm), carrageenan, gelatin, pullulan, sodium alginate, and the like. In certain embodiments, the thickening agent comprises one or more of xanthan gum, carrageenan, or sodium carboxymethyl cellulose. The proportion by weight of thickener in the oral care composition is typically from 0.2 to 2%.

According to certain embodiments of the present application, active ingredients such as antibacterial agents, anticaries agents, anti-sensitivity agents, and/or whitening agents may be further included in the oral care compositions.

By "antibacterial agent" is meant a chemical substance that is capable of maintaining the growth or reproduction of certain microorganisms in an oral care composition below a necessary level over a period of time. Exemplary antimicrobial agents include, but are not limited to: tetrahydrocurcumin, cetylpyridinium chloride, triclosan, and the like.

"anticaries agent" means a substance having an inhibitory effect on caries, for example, a substance which enhances the anticaries ability of teeth by decreasing the solubility of enamel hydroxyapatite, or a substance which controls plaque, inhibiting bacterial growth. Exemplary anticaries agents include, but are not limited to, phosphorus-containing agents (calcium phosphate, magnesium glycerophosphate, calcium lactate phosphate, sodium caseinate, etc.), or arginine and its derivatives. Preferably, in certain embodiments, the anticaries agent comprises a fluoride ion source.

An "anti-sensitivity agent" refers to a substance that prevents or treats dentinal hypersensitivity by inhibiting nerve impulses or being capable of closing or decreasing the permeability of dentinal tubules. Exemplary anti-sensitivity agents include, but are not limited to: potassium ion sources such as dipotassium glycyrrhizinate, potassium fluoride, potassium nitrate, potassium chloride and the like.

The "whitening agent" refers to a substance having a whitening effect on teeth. Exemplary whitening agents include, but are not limited to: a peroxide bleaching agent.

The foam amount detection method in the application comprises the following steps:

detecting the foam amount of the formula according to a GB 8372-2001 foam amount detection method

The detection method of cotton density in the application comprises the following steps:

1) evaluation group establishment

Selecting 30 qualified feeling evaluators according to GB/T16291.1-2012 and GB/T12311-2012;

2) correction of foam evaluation criteria by an evaluator

The Oral-B gum & amino repair toothpaste is used as a reference, and the foam softness score is 6; the black person dual mint toothpaste is taken as a reference, and the foam density score is 9 points; the pudding is used as a reference score of 15, and the scores of evaluators are unified.

Accurately weighing 1.0g of toothpaste, rinsing the mouth for 5s with a gargle, spitting out, brushing teeth on the outer surface of teeth for 40 s from left to right according to a pasteurization tooth brushing method, evaluating the density of foam in the oral cavity, evaluating an evaluator on a scale of 15cm according to the self feeling, repeatedly measuring each reference sample for three times, and averaging the results of the three times to enable the evaluator to memorize the self grading strength. Then, calculating the evaluation result of the reference sample of each evaluator according to a comprehensive rescaling method specified in the value estimation method of the national standard GB _ T19547-2004 to obtain a correction factor;

3) sample evaluation

Accurately weighing 1.0g of toothpaste, gargling the toothpaste for 5s, spitting out, brushing teeth on the outer surface of teeth for 40 s from left to right according to a pasteurization tooth brushing method, and evaluating the density of foam in the oral cavity, wherein each evaluator evaluates the foam on a 15cm scale according to the self feeling; the scale values of thirty evaluators were corrected by the above correction values, and then subjected to the evaluation results of variance analysis, and the obtained evaluation results were in accordance with statistical differences.

Example 1, comparative examples 1 to 5:

an oral care composition comprises the following raw materials in the following table 1 by weight proportion, and the total amount is 100 parts and is prepared into toothpaste according to the conventional method. The measured data of the foam quantity and the foam density are respectively shown in the table 2 and the table 3.

Table 1:

table 2: the amount of foam in each toothpaste in table 1 above was measured as follows:

raw materials	Comparative example 1	Comparative example 2	Comparative example 3	Comparative example 4	Comparative example 5	Example 1
							Amount of foam (mm)	120.00	99.00	115.00	122.00	124.00	125.00

Table 3: the foam density of each toothpaste in table 1 above was measured as follows:

as can be seen from the data in tables 1-3:

a. comparative example 1, the foam level was 120 and the foam density was 9.8, both at higher levels, when no baking soda was added.

b. Comparative example 2, in an oral care composition using silica as an abrasive, the amount of foam was 99 and the foam density was 8.7, both of which were significantly reduced when baking soda was added.

c) Comparative example 3, in an oral care composition with silica as an abrasive, with the addition of baking soda and the simultaneous presence of a dual surfactant, the foam quantity and foam density, which were drastically reduced by the addition of baking soda, rose back to a foam quantity of 115 with a foam density of 9.1; but still slightly lower than in comparative example 1.

d) Comparative example 4, in an oral care composition with silica as abrasive, with the addition of baking soda and the simultaneous presence of a dual surfactant, with the addition of palm oil, there was a minor improvement in the amount of foam and foam density, 122.00 and 9.2 respectively, compared to the case of comparative example 3; the foam amount was restored to the case of comparative example 1 without adding sodium bicarbonate, but the foam density was somewhat different from that of comparative example 1 without adding sodium bicarbonate.

e) Comparative example 5 compared to comparative example 4, the palm oil was replaced with castor oil, and the effects were similar.

f) Example 1, when baking soda was added to an oral care composition using silica as an abrasive, and a double surfactant was simultaneously present, and coconut oil was added, not only was the amount of foam 125 restored to the level of that when no baking soda was added, but also the degree of foam softness was greatly improved by 10.9, as compared with comparative examples 3 and 1.

In summary, in the oral care composition using silicon dioxide as an abrasive, the foam amount and the foam density are both greatly reduced when sodium bicarbonate is added; the foam amount can be restored to the original level by adding the dual surfactant system, but the foam density is still low, and the foam amount is not only restored to the original level (slightly higher) but also the foam density is greatly improved from the original level by adding one coconut oil of vegetable oil.

Examples 2 to 5:

an oral care composition comprises the following raw materials in a weight ratio of table 4, and the total amount is 100 parts and is prepared into toothpaste according to the conventional method. The measured data of the foam quantity and the foam density are respectively shown in the table 5 and the table 6.

TABLE 4

Starting materials	Example 2	Example 1	Example 3	Example 4	Example 5
						Sorbitol	40.00	40.00	40.00	40.00	40.00
Glycerol	8.00	8.00	8.00	8.00	8.00
						Polyethylene glycol	3.00	3.00	3.00	3.00	3.00
Carrageenan	0.20	0.20	0.20	0.20	0.20
						Cellulose gum	0.35	0.35	0.35	0.35	0.35
Sodium fluoride	0.22	0.22	0.22	0.22	0.22
						Saccharin sodium salt	0.25	0.25	0.25	0.25	0.25
Silicon dioxide	25.00	25.00	25.00	25.00	25.00
						Essence	1.20	1.20	1.20	1.20	1.20
Sodium dodecyl sulfate	2.20	2.20	2.20	2.20	2.20
						Cocoamidopropyl betaine	0.70	0.70	0.70	0.70	0.70
Baking soda	0.50	0.50	0.50	0.50	0.50
						Coconut oil	0.05	0.10	0.50	1.00	1.20
Deionized water	Is added to 100	Is added to 100	Is added to 100	Is added to 100	Is added to 100

Table 5: the amount of foam of each toothpaste in Table 4 above was measured as follows

Raw materials	Example 2	Example 1	Example 3	Example 4	Example 5
						Amount of foam (mm)	120.00	125.00	121.00	118.00	107.00

Table 6: the foam density of each toothpaste in table 4 above was measured as follows:

starting materials	Example 2	Example 1	Example 3	Example 4	Example 5
						Foam degree (0-15)	9.30	10.90	11.50	12.90	13.20

As can be seen from tables 4 to 6 above:

the amount of coconut oil added has a substantial effect on the amount of foam and foam density of the oral care composition (composition including at least silica, baking soda, bi-surfactant): when the coconut oil is added in an amount of less than 0.1%, the foam amount and the foam density of the composition cannot be simultaneously increased, and particularly the foam density cannot be increased; when the addition amount of the coconut oil reaches 0.1%, the foam amount and the foam density of the composition can be improved at the same time, and particularly the foam density is remarkably improved; when the coconut oil is added to 1.2%, the foam density in the oral care composition is remarkably improved, but the foam amount is remarkably reduced.

Example 6, comparative examples 6-8:

an oral care composition comprises the following raw materials in the following table 7 weight ratio, and the total amount is 100 parts and is prepared into toothpaste according to the conventional method. The measured data of the foam quantity and the foam density are respectively shown in the table 8 and the table 9.

Table 7:

raw materials	Comparative example 6	Comparative example 7	Comparative example 8	Example 6
					Sorbitol	19.000	19.000	19.000	19.000
Cellulose gum	1.000	1.000	1.000	1.000
					Sodium monofluorophosphate	0.796	0.796	0.796	0.796
Saccharin sodium salt	0.250	0.250	0.250	0.250
					Calcium carbonate	32.000	32.000	32.000	32.000
Sodium dodecyl sulfate	2.300	2.300	2.300	2.300
					Cocoamidopropyl betaine	/	/	0.70	0.70
Baking soda	/	0.50	0.50	0.50
					Coconut oil	/	/	/	0.10
Deionized water	Is added to 100	Is added to 100	Is added to 100	Is added to 100

Table 8: the amount of foam of each toothpaste shown in Table 7 above was measured as follows

Starting materials	Comparative example 6	Comparative example 7	Comparative example 8	Example 6
					Amount of foam (mm)	112.00	96.00	108.00	110.00

Table 9: the foam density of each toothpaste in table 7 above was measured as follows:

raw materials	Comparative example 6	Comparative example 7	Comparative example 8	Example 6
					Degree of foam density (0-15)	8.80	8.00	8.40	8.90

As can be seen from tables 7 to 9: if the abrasive in the oral care composition is not silica, but is of another type (e.g., calcium carbonate), the inclusion of coconut oil can also increase the lather density of the composition for this system, but not as significantly as for compositions in which silica is the abrasive base. That is, the inclusion of coconut oil may increase the foam density more effectively in an oral care composition where the abrasive is silica.

Examples 7 to 8:

an oral care composition comprises the following raw materials in the following table 10 weight ratio, and the total amount is 100 parts and is prepared into toothpaste according to the conventional method. The measured data of the amount of foam and the density of the foamed material are shown in tables 11 and 12, respectively.

Table 10:

raw materials	Example 7	Example 8
			Sorbitol	40.00	40.00
Glycerol	8.00	8.00
			Polyethylene glycol	3.00	3.00
Carrageenan	0.20	0.20
			Cellulose gum	0.35	0.35
Sodium fluoride	0.22	0.22
			Saccharin sodium salt	0.25	0.25
Silicon dioxide	25.00	25.00
			Essence	1.20	1.20
Sodium dodecyl sulfate	1.50	2.50
			Cocoamidopropyl betaine	0.50	1.50
Baking soda	0.10	5.00
			Coconut oil	0.10	0.10
Deionized water	Is added to 100	Is added to 100

Table 11: the amount of foam of each toothpaste shown in Table 10 was measured as follows

Raw materials	Example 7	Example 8
			Amount of foam (mm)	87.00	110.00

Table 12: the foam density of each toothpaste in table 10 above was measured as follows:

raw materials	Example 7	Example 8
			Degree of foam density (0-15)	9.90	10.30

The effect of dual surfactant system addition on the oral care compositions of the present invention can be seen in tables 10-12.

It should be understood that the above-described embodiments of the present invention are merely examples for clearly illustrating the present invention, and are not intended to limit the embodiments of the present invention. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. Not all embodiments are exhaustive. All obvious changes and modifications which are obvious to the technical scheme of the invention are covered by the protection scope of the invention.

Claims

1. Use of coconut oil in an oral care composition to increase foam firmness.

2. The use according to claim 1, wherein the oral care composition comprises:

a) the content of the baking soda is as follows,

b) an anionic surfactant, a surfactant,

c) a cationic or amphoteric surfactant, and a surfactant,

d) coconut oil, and

e) an orally acceptable carrier.

3. Use according to claim 2, characterized in that: the oral care composition further comprises silica.

4. Use according to claim 2, characterized in that: the anionic surfactant is sodium dodecyl sulfate.

5. Use according to claim 2, characterized in that: the cationic or amphoteric surfactant is cocamidopropyl betaine.

6. Use according to claim 2, characterized in that: the anionic surfactant is present in the oral care composition in a mass proportion of 1.5 to 2.5%.

7. The oral care composition of claim 2, wherein: the cationic or amphoteric surfactant is present in the oral care composition in a mass ratio of 0.5 to 1.5%.

8. Use according to claim 2, characterized in that: the coconut oil accounts for 0.1-1.2% of the oral care composition by mass.

9. Use according to claim 2, characterized in that: the oral care composition may further comprise other abrasives including one or more of calcium carbonate, calcium phosphate, calcium hydrogen phosphate.

10. Use according to claim 1, characterized in that: the oral care composition comprises a toothpaste, gel or tooth powder.