CN110507696A - It is a kind of to itch the antibacterial liquid and preparation method thereof of effect with foot smell prevention foot - Google Patents
It is a kind of to itch the antibacterial liquid and preparation method thereof of effect with foot smell prevention foot Download PDFInfo
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- CN110507696A CN110507696A CN201910777513.6A CN201910777513A CN110507696A CN 110507696 A CN110507696 A CN 110507696A CN 201910777513 A CN201910777513 A CN 201910777513A CN 110507696 A CN110507696 A CN 110507696A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
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Abstract
The invention discloses a kind of the problem of itching the antibacterial liquid and preparation method thereof of effect with foot smell prevention foot, being to solve existing treatment foot odour drug.The present invention includes the raw material of following parts by weight: 1-10 parts of shrubby sophora extract, 0.1-1 parts of quaternary ammonium salt disinfectant, 1-20 parts of betadex derivative, 0.5-2 parts of plant gel, 0.5-3 parts of vitamin, 0.0001-0.001 parts of essence, 70-95 parts of water and 1-5 parts of urea.This product raw material sources are extensive, the finished product of preparation can inhibit bacterium, fungi to breed, the prevention and treatment ringworm of the foot, psoriasis no skin irritation, prevent foot odour, foot from itching, pedal skin is dry and cracked, pruitus and coarse generation, the skin that can be also used for other positions, has broad application prospects.
Description
Technical field
It is specifically a kind of to itch the antibacterial liquid of effect with foot smell prevention foot the present invention relates to antibacterial field.
Background technique
With the increase and the improvement of people's living standards of people's income, body of the more and more people for oneself
Situation focuses more on.
Foot surfaces form the ringworm of the foot easily by bacterium, fungal infection, and foot infection and foot generate stink itch and do
Correlation is split, foot odour is exactly a kind of common symptom, and under the conditions of hidrosis, bacterium mass propagation on foot simultaneously decomposes keratoprotein,
Along with urea, the lactic acid in sweat, a kind of stink can be thus issued.
For the puzzlement from foot odour, people can go treatment foot odour using drug.Traditional drug is for treating foot odour
It is by sterilizing, inhibiting foot bacterium and fungi to realize.Most of being irritating to the skin property of drug, no maintenance effect, to skin
Skin has injury, cannot smear use for a long time.Bacterium, fungi are that the intrinsic microorganism of the Nature can not be killed, skin surface
Environment determines the primary condition that bacterium, fungi breed, and only inhibits bacterium, fungi to breed by changing skin surface environment,
Method can be effectively prevented, people are also in the research for carrying out related fields.
Summary of the invention
The embodiment of the present invention be designed to provide it is a kind of itch the antibacterial liquid of effect with foot smell prevention foot, to solve above-mentioned back
The problem of being proposed in scape technology.
To achieve the above object, the embodiment of the present invention provides the following technical solutions:
It is a kind of to itch the antibacterial liquid of effect with foot smell prevention foot, the raw material including following parts by weight: 1-10 parts of shrubby sophora extract, quaternary ammonium
0.1-1 parts of salt disinfectant, 1-20 parts of betadex derivative, 0.5-2 parts of plant gel, 0.5-3 parts of vitamin, essence
0.0001-0.001 parts, 70-95 parts of water and 1-5 parts of urea, shrubby sophora extract have bacteriostasis, can inhibit bacterium, fungi, season
Ammonium salt disinfectant has broad-spectrum antibacterial effect, and shrubby sophora extract is combined with quaternary ammonium salt disinfectant to be inhibited more to have to bacterium, fungi
Effect, bacteriostasis rate is up to 98% or more；Shrubby sophora extract, quaternary ammonium salt disinfectant combine to form inclusion with betadex derivative
Object more can increase fungistatic effect reduction to the irritation of skin, while betadex derivative has the function of removing stink；
Shrubby sophora extract, quaternary ammonium salt disinfectant, betadex derivative and plant gel form an aqueous gel system, can be in skin
Skin surface forms one layer of medicament slow release protective film, reaches slow release effect, improves fungistatic effect, reduces the irritation to skin, dimension
Raw element and urea can provide nutrition for skin.
As further embodiment of the embodiment of the present invention: quaternary ammonium salt disinfectant is dodecyl trimethyl ammonium chloride, 12
Zephiran, dodecyl dimethyl benzyl ammonium bromide, stearyl dimethyl benzyl ammonium chloride, cyano season
Any one in ammonium salt, double C quaternary ammonium alkyl bromides, poly- azacyclo- quaternary ammonium salt, polyquaternium and bi-quaternary ammonium salt.
As further embodiment of the embodiment of the present invention: betadex derivative includes HYDROXYPROPYL BETA-CYCLODEXTRIN, sulphur
At least one of butyl betadex, methyl betadex and hydroxyl butyl betadex.
As further embodiment of the embodiment of the present invention: vitamin is the mixture of vitamin E and vitamin B6.
As further embodiment of the embodiment of the present invention: plant gel includes guar gum, peach gum, Arabic gum and quaternary ammonium
One of salt guar gum or several mixtures.
As further embodiment of the embodiment of the present invention: shrubby sophora extract is the deionization that 5-8 times of its weight is added in kuh-seng
It is decocted 2-3 times in water and under 85-96 degrees Celsius, filters and merging filtrate obtains.
It is described with foot smell prevention foot itch effect antibacterial liquid preparation method, the specific steps are as follows: raw material is mixed
Uniformly, 50-80 minutes are stood.
Compared with prior art, the beneficial effect of the embodiment of the present invention is:
This product raw material sources are extensive, the finished product of preparation to no skin irritation, bacterium, fungi can be inhibited to breed, the prevention and treatment ringworm of the foot,
Psoriasis, prevents foot odour, foot from itching, pedal skin is dry and cracked, pruitus and coarse generation, has broad application prospects.
Specific embodiment
The technical solution of the patent is explained in further detail With reference to embodiment.
Embodiment 1
It is a kind of to itch the antibacterial liquid of effect, including following raw material with foot smell prevention foot: 1 kilogram of shrubby sophora extract, bi-quaternary ammonium salt disinfection
0.1 kilogram of agent, 1 kilogram of betadex derivative, 0.5 kilogram of plant gel, 0.5 kilogram of vitamin, 0.0001 kilogram of essence,
70 kilograms and 1 kilogram of urea of water, shrubby sophora extract has bacteriostasis, can inhibit bacterium, fungi, and quaternary ammonium salt disinfectant has wide
Bacteriostasis is composed, shrubby sophora extract is combined with quaternary ammonium salt disinfectant inhibits more effective to bacterium, fungi, and bacteriostasis rate is up to 98%
More than；Shrubby sophora extract, quaternary ammonium salt disinfectant combine to form inclusion compound with betadex derivative, more can increase antibacterial effect
Fruit reduces the irritation to skin, while betadex derivative has the function of removing stink；Shrubby sophora extract, quaternary ammonium salt
Disinfectant, betadex derivative and plant gel form an aqueous gel system, can form one layer of medicine in skin surface
Object is sustained protective film, reaches slow release effect, improves fungistatic effect, reduces the irritation to skin, vitamin and urea can be
Skin provides nutrition, and shrubby sophora extract is that kuh-seng is added in the deionized water of 7 times of its weight and decocts 3 under 88 degrees Celsius
It is secondary, it filters and merging filtrate obtains.
Quaternary ammonium salt disinfectant is double C quaternary ammonium alkyl bromides.Betadex derivative is sulphur butyl betadex and hydroxyl
The mixture of butyl betadex.Vitamin is the mixture of vitamin E and vitamin B6.Plant gel uses cluster bean
Glue.
It is described with foot smell prevention foot itch effect antibacterial liquid preparation method, the specific steps are as follows: raw material is mixed
Uniformly, 70 minutes are stood.
Embodiment 2
It is a kind of to itch the antibacterial liquid of effect, including following raw material with foot smell prevention foot: 3.8 kilograms of shrubby sophora extract, dodecyl three
0.4 kilogram of ammonio methacrylate, 8.6 kilograms of HYDROXYPROPYL BETA-CYCLODEXTRIN, 1 kilogram of plant gel, 1.36 kilograms of vitamin, essence
0.0002 kilogram, 78 kilograms of water and 2.1 kilograms of urea, shrubby sophora extract have bacteriostasis, can inhibit bacterium, fungi, and 12
Alkyl trimethyl ammonium chloride has broad-spectrum antibacterial effect, and shrubby sophora extract is combined with dodecyl trimethyl ammonium chloride to thin
Bacterium, fungi inhibit more effective, and bacteriostasis rate is up to 98% or more；Shrubby sophora extract, dodecyl trimethyl ammonium chloride and hydroxypropyl times
His cyclodextrin combines to form inclusion compound, more can increase fungistatic effect and reduces to the irritation of skin, while hydroxypropyl times his ring
Dextrin has the function of removing stink；Shrubby sophora extract, dodecyl trimethyl ammonium chloride, HYDROXYPROPYL BETA-CYCLODEXTRIN and plant
One aqueous gel system of gel-forming can form one layer of medicament slow release protective film in skin surface, reach slow release effect, improve
Fungistatic effect reduces the irritation to skin, and vitamin and urea can provide nutrition for skin.Plant gel include peach gum and
The mixture of Arabic gum
It is described with foot smell prevention foot itch effect antibacterial liquid preparation method, the specific steps are as follows: raw material is mixed at 25 degrees Celsius
Conjunction stirs evenly, and stands 60 minutes.
Embodiment 3
It is a kind of to itch the antibacterial liquid of effect, including following raw material with foot smell prevention foot: 7.7 kilograms of shrubby sophora extract, quaternary ammonium salt disinfection
0.81 kilogram of agent, 16.2 kilograms of betadex derivative, 1.55 kilograms of plant gel, 2.3 kilograms of vitamin, essence 0.0008
Kilogram, 86.4 kilograms of water and 3.8 kilograms of urea, shrubby sophora extract has bacteriostasis, can inhibit bacterium, fungi, quaternary ammonium salt disappears
Toxic agent has broad-spectrum antibacterial effect, and shrubby sophora extract is combined with quaternary ammonium salt disinfectant inhibits more effective to bacterium, fungi, antibacterial
Rate is up to 98% or more；Shrubby sophora extract, quaternary ammonium salt disinfectant combine to form inclusion compound with betadex derivative, more can
Increase fungistatic effect reduction to the irritation of skin, while betadex derivative has the function of removing stink；Kuh-seng mentions
Object, quaternary ammonium salt disinfectant, betadex derivative and plant gel is taken to form an aqueous gel system, it can be in skin surface
Form one layer of medicament slow release protective film, reach slow release effect, improve fungistatic effect, reduce the irritation to skin, vitamin and
Urea can provide nutrition for skin.
Quaternary ammonium salt disinfectant is dodecyl dimethyl benzyl ammonium bromide, stearyl dimethyl benzyl ammonium chloride.Times he
Cyclodextrine derivatives include the mixture of HYDROXYPROPYL BETA-CYCLODEXTRIN, methyl betadex and hydroxyl butyl betadex.It plants
Object gel includes the mixture of guar gum, Arabic gum and quaternary ammonium salt guar gum.Shrubby sophora extract is that its is added is heavy for kuh-seng
It is decocted 3 times in the deionized water of 5 times of amount and under 90 degrees Celsius, filters and merging filtrate obtains.
It is described with foot smell prevention foot itch effect antibacterial liquid preparation method, the specific steps are as follows: by raw material with 240rpm
Revolving speed be mixed evenly, stand 65 minutes.
Embodiment 4
It is a kind of to itch the antibacterial liquid of effect, including following raw material with foot smell prevention foot: 10 kilograms of shrubby sophora extract, polyquaternium 1,000
Gram, 20 kilograms of betadex derivative, 2 kilograms of plant gel, 3 kilograms of vitamin, 0.001 kilogram, 95 kilograms of essence and urine
5 kilograms of element, shrubby sophora extract have bacteriostasis, can inhibit bacterium, fungi, and quaternary ammonium salt disinfectant has broad-spectrum antibacterial effect,
Shrubby sophora extract is combined with polyquaternium inhibits more effective to bacterium, fungi, and bacteriostasis rate is up to 98% or more；Shrubby sophora extract,
Polyquaternium combines to form inclusion compound with betadex derivative, more can increase stimulation of the fungistatic effect reduction to skin
Property, while betadex derivative has the function of removing stink；Shrubby sophora extract, polyquaternium, betadex are derivative
Object and plant gel form an aqueous gel system, can form one layer of medicament slow release protective film in skin surface, reach sustained release
Effect improves fungistatic effect, reduces the irritation to skin, vitamin and urea can provide nutrition for skin.
Betadex derivative includes HYDROXYPROPYL BETA-CYCLODEXTRIN, sulphur butyl betadex, methyl betadex
With the mixture of hydroxyl butyl betadex.Vitamin is the mixture of vitamin E and vitamin B6.Plant gel includes Guar
Bean gum, peach gum, Arabic gum and quaternary ammonium salt guar gum mixture.
It is described with foot smell prevention foot itch effect antibacterial liquid preparation method, the specific steps are as follows: raw material is mixed
Uniformly, 80 minutes are stood.
Test to the product of embodiment 4, Inspection Unit: Beijing Biotechnology Co., Ltd of four generations under one roof, sample by
Reason PLTC201811002824, lot number: 181111, sample date 2018.11.27 is met, date 2019.4.2 has been inspected.It examines
And Appreciation gist: " disinfection technology standard " (version in 2002), GB 15979-2002 " Disposable Sanitary Accessory health mark
It is quasi- ", Q/SSTT001-2018 " delicate fragrance feel well antibacterial liquid ".
Inspection result: first, which is brown liquid, is visible by naked eyes impurity, examines 18.2 DEG C of temperature, relative humidity
64.3%, meet the requirement of company standard Q/SSTT 001-2018 " delicate fragrance feel well antibacterial liquid "；
Second, which is 5.72, acidometer: Shanghai instrument electricity PHS-25, correction buffer: phthalic acid
Hydrogen potassium buffer, 4.00,25.0 DEG C of pH value；Phosphate buffer, examines 25.0 DEG C of temperature by 6.86,25.0 DEG C of pH value,
Relative humidity 61.9% meets the requirement of company standard Q/SSTT 001-2018 " delicate fragrance feel well antibacterial liquid "；
Third, the sample bacterium total plate count, fungus colony sum < 1CFU/mL, coliform, staphylococcus aureus,
Pseudomonas aeruginosa, hemolytic streptococcus are not detected, and micro-biology experiment testing result meets GB 15979-2002 and " disposably makes
With amenities sanitary standard " requirement, instrument and equipment: intelligent constant-temperature constant humidity cabinet HWS-150；Biochemical cultivation case SPX-
250B-Z examines 18-20 DEG C of temperature, relative humidity 45-60%；
4th, under the conditions of 18-20 DEG C, the sample effect 30 minutes to Escherichia coli, staphylococcus aureus, Candida albicans
The equal > 60% of the average bacteriostasis rate of bacterium meets the requirement of company standard Q/SSTT 001-2018 " delicate fragrance feel well antibacterial liquid ", examination
Test bacterial strain: staphylococcus aureus (ATCC6538), Escherichia coli (8099), Candida albicans (ATCC10231), by Guangdong Province
Food microorganisms safety engineering research and development centre food safety Culture Collection Center provides, and takes its 5th generation fresh
Slant culture is tested；
5th, sample good seal stores 3 months (90d), under the conditions of 18-20 DEG C, the sample in 37 DEG C of insulating boxs
Effect 30 minutes to Escherichia coli, staphylococcus aureus, Candida albicans the equal > 60% of average bacteriostasis rate, meet enterprise mark
The requirement of quasi- Q/SSTT001-2018 " delicate fragrance feel well antibacterial liquid ", test strain: staphylococcus aureus (ATCC6538), big
Enterobacteria (8099), Candida albicans (ATCC10231), by food microorganisms safety engineering research and development centre, Guangdong Province
Food safety Culture Collection Center provides, its 5th generation fresh slant culture is taken to be tested；
6th, which belongs to nonirritant to the multiple intact skin stimulus intensity of cavy, meets " disinfection technology standard " (2002
Year version) requirement, kind: cavy, Dunkin Hartley 3；Source: the multifarious good emerging limited public affairs of biotechnology in Wuhan City
Department, production licence: SCXK (Hubei Province) 2016-0011；Grade: regular grade；Animal certificate number: NO.42010000003788；Property
It is other: female；Weight range: 300-350g；Feed: regular grade cavy maintains feed；Animal room environmental: temperature: 16-26 DEG C, phase
To humidity: 40%-70%；Animal house quality certification number: SYXK (Hubei Province) 2017-0096；Main agents: the Nacl that mass fraction is 0.9%
Injection.Given the test agent administration way: according to intact skin irritant test side multiple in " disinfection technology standard " (version in 2002)
Method carries out: before the test for 24 hours, the hair of guinea pig back backbone two sides being removed, skin must not be damaged.Unhairing range, it is left and right each
About 3cm × 3cm.Next day directly drips tested material 0.5mL stoste in 2 layers of -4 layers of yarn that area is 2.5cm × 2.5cm
It on cloth and applies on side skin of unhairing surface, then with one layer of non-stimulated plastic foil or oilpaper covering, then with non-stimulated adhesive plaster
It is fixed.The Nacl injection that the other side applies 0.9% is used as control, and the 4h after smearing is cleaned with warm water, removes residue.Daily
It smears once, continuously smears 14d.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Within mind and principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.
In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped
Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should
It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art
The other embodiments being understood that.
Claims (7)
1. a kind of itch the antibacterial liquid of effect with foot smell prevention foot, which is characterized in that the raw material including following parts by weight: kuh-seng extracts
1-10 parts of object, 0.1-1 parts of quaternary ammonium salt disinfectant, 1-20 parts of betadex derivative, 0.5-2 parts of plant gel, vitamin
0.5-3 parts, 0.0001-0.001 parts of essence, 70-95 parts of water and 1-5 parts of urea.
2. according to claim 1 itch the antibacterial liquid of effect with foot smell prevention foot, which is characterized in that the quaternary ammonium salt disinfection
Agent is dodecyl trimethyl ammonium chloride, dodecyl benzyl dimethyl ammonium chloride, dodecyl dimethyl benzyl ammonium bromide, ten
Eight zephirans, cyano quaternary ammonium salt, double C quaternary ammonium alkyl bromides, poly- azacyclo- quaternary ammonium salt, polyquaternium and double
Any one in quaternary ammonium salt.
3. according to claim 1 itch the antibacterial liquid of effect with foot smell prevention foot, which is characterized in that the betadex
Derivative includes HYDROXYPROPYL BETA-CYCLODEXTRIN, sulphur butyl betadex, methyl betadex and hydroxyl butyl betadex
At least one of.
4. according to claim 1 itch the antibacterial liquid of effect with foot smell prevention foot, which is characterized in that the vitamin is dimension
The mixture of raw element E and vitamin B6.
5. according to claim 1 or 3 itch the antibacterial liquid of effect with foot smell prevention foot, which is characterized in that the plant is solidifying
Glue includes one of guar gum, peach gum, Arabic gum and quaternary ammonium salt guar gum or several mixtures.
6. according to claim 1 itch the antibacterial liquid of effect with foot smell prevention foot, which is characterized in that the shrubby sophora extract
It is added in the deionized water of 5-8 times of its weight for kuh-seng and is decocted 2-3 times under 85-96 degrees Celsius, filter and merge filter
Liquid obtains.
7. it is a kind of as described in claim 1-6 is any with foot smell prevention foot itch effect antibacterial liquid preparation method, feature
It is, the specific steps are as follows: raw material is mixed evenly, stands 50-80 minutes.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111631996A (en) * | 2020-06-16 | 2020-09-08 | 徐永福 | Skin-nourishing hand-washing-free disinfection gel solution and preparation method thereof |
| CN111685132A (en) * | 2020-06-16 | 2020-09-22 | 徐永福 | Peculiar smell-removing compound double-chain quaternary ammonium salt disinfectant and preparation method thereof |
| CN111973466A (en) * | 2020-08-26 | 2020-11-24 | 中山市凯蕾护理用品有限公司 | Antibacterial and deodorant composition and preparation method and application thereof |
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