CN110384111A - A kind of synergist of lactic acid bacteria and its application - Google Patents

A kind of synergist of lactic acid bacteria and its application Download PDF

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Publication number
CN110384111A
CN110384111A CN201910648602.0A CN201910648602A CN110384111A CN 110384111 A CN110384111 A CN 110384111A CN 201910648602 A CN201910648602 A CN 201910648602A CN 110384111 A CN110384111 A CN 110384111A
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parts
lactic acid
acid bacteria
synergist
minutes
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王明星
黄忠平
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ZHONGSHUN BIOTECHNOLOGY CO Ltd WUXI
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ZHONGSHUN BIOTECHNOLOGY CO Ltd WUXI
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/16Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds containing nitrogen-to-oxygen bonds
    • A01N33/18Nitro compounds
    • A01N33/20Nitro compounds containing oxygen or sulfur attached to the carbon skeleton containing the nitro group
    • A01N33/22Nitro compounds containing oxygen or sulfur attached to the carbon skeleton containing the nitro group having at least one oxygen or sulfur atom and at least one nitro group directly attached to the same aromatic ring system
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A01N59/06Aluminium; Calcium; Magnesium; Compounds thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • A61K31/06Phenols the aromatic ring being substituted by nitro groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/194Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004Monosaccharides having only carbon, hydrogen and oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/42Phosphorus; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Plant Pathology (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to a kind of synergist of lactic acid bacteria and its applications, belong to technical field of aquaculture.It includes sodium butyrate, citric acid, compound sodium nitrophenolate, magnesium sulfate, potassium dihydrogen phosphate, glucose;Above-mentioned raw materials are uniformly mixed at normal temperature, are packaged into the 500g/ bags of synergist to get lactic acid bacteria.The present invention is directed to lactic acid bacteria main usage scenario on aquatic products, by supplementing corresponding promotor and synergistic substance, is used cooperatively with lactic acid bacteria, promotes lactobacter growth and promote its improvement animal intestinal tract and promotion water plant growth and other effects.The present invention is used by 250g/ mus of cooperation lactic acid bacterias, has tender shoots to grow using a large amount of water plants two days later, river crab enteron aisle is full, and intestinal flora is normal.

Description

A kind of synergist of lactic acid bacteria and its application
Technical field
The present invention relates to a kind of synergist of lactic acid bacteria, belong to technical field of aquaculture.
Background technique
Lactic acid bacteria is one kind more common in probiotics, and lactic acid bacteria produces a large amount of organic acids etc. in the metabolic process Acidic materials can make gastrointestinal tract keep slant acidity environment, this is exactly conducive to the effect for the digestive enzymes that pH value is acidity, Also the digestion and absorption for just increasing nutrient may additionally facilitate absorption of the cultivated animals to inorganic ions such as calcium, phosphorus, thus sharp It is developed in bone and crust.In addition lactic acid bacteria decomposes organic matter and generates small molecule nutriment, is conducive to river crab pond water plant Growth.Lactic acid bacteria on aquatic products using more and more extensive, but practical effect also needs to further strengthen, and is for example used to promote Water inlet grass growth, because belonging to indirect facilitation, will the expection of raiser be often not achieved greatly in dosage.
Summary of the invention
The purpose of the present invention is overcoming above-mentioned shortcoming, to provide synergist and its application of a kind of lactic acid bacteria, needle To lactic acid bacteria, main usage scenario is made by supplementing corresponding promotor and synergistic substance with lactic acid bacteria cooperation on aquatic products With, promote lactobacter growth and promote its improvement animal intestinal tract and promote water plant growth and other effects.
According to technical solution provided by the invention, a kind of synergist of lactic acid bacteria, formula rate is as follows by weight: 25-45 parts of sodium butyrate, 5-15 parts of citric acid, 1-15 parts of compound sodium nitrophenolate, 1-15 parts of magnesium sulfate, 1-15 parts of potassium dihydrogen phosphate, grape It is 10-35 parts sugared;Above-mentioned raw materials are stirred 30-60 minutes, 20-60 revs/min of revolving speed through double-shaft paddle mixer at normal temperature Clock is packaged into the 500g/ bags of synergist to get lactic acid bacteria.
As a further improvement of the present invention, a kind of synergist of lactic acid bacteria, formula rate are as follows by weight: institute State 25 parts of sodium butyrate, 10 parts of citric acid, 12 parts of compound sodium nitrophenolate, 10 parts of magnesium sulfate, 8 parts of potassium dihydrogen phosphate, 35 parts of glucose;It will be upper State raw material to be stirred 30 minutes through double-shaft paddle mixer at normal temperature, 50 revs/min of revolving speed, be packaged into 500g/ bags to get The synergist of lactic acid bacteria.
As a further improvement of the present invention, a kind of synergist of lactic acid bacteria, formula rate are as follows by weight: institute State 30 parts of sodium butyrate, 15 parts of citric acid, 15 parts of compound sodium nitrophenolate, 8 parts of magnesium sulfate, 12 parts of potassium dihydrogen phosphate, 20 parts of glucose;It will be upper State raw material to be stirred 40 minutes through double-shaft paddle mixer at normal temperature, 40 revs/min of revolving speed, be packaged into 500g/ bags to get The synergist of lactic acid bacteria.
As a further improvement of the present invention, a kind of synergist of lactic acid bacteria, formula rate are as follows by weight: institute State 40 parts of sodium butyrate, 6 parts of citric acid, 8 parts of compound sodium nitrophenolate, 12 parts of magnesium sulfate, 9 parts of potassium dihydrogen phosphate, 25 parts of glucose;It will be above-mentioned Raw material is stirred 35 minutes through double-shaft paddle mixer at normal temperature, 25 revs/min of revolving speed, is packaged into 500g/ bags to get cream The synergist of sour bacterium.The synergist is powdered.
As a further improvement of the present invention, the synergist for preparing lactic acid bacteria is made on one 10 mu of crab pool of Changzhou academic circle With, being blacked a little using the water plant root in preceding pond, a small amount of river crab has enteritis phenomenon, it is used by 250g/ mus of cooperation lactic acid bacterias, Synergist, lactic acid bacteria, water three weight ratio press 1:1:100, be sufficiently mixed in bucket or cabin dissolution after ten minutes, full pond sprinkle It spills, there is tender shoots to grow using a large amount of water plants two days later, river crab enteron aisle is full, and intestinal flora is normal.
Compared with the prior art the present invention has the advantage that
Synergist provided by the invention, for lactic acid bacteria on aquatic products main usage scenario, pass through the corresponding promotor of supplement And synergistic substance, it is used cooperatively with lactic acid bacteria, promotes lactobacter growth and promote its improvement animal intestinal tract and promote water plant growth And other effects.
Specific embodiment
The present invention will be further described in conjunction with the embodiments below:
Embodiment 1
A kind of synergist of lactic acid bacteria, formula rate are as follows by weight: 25 parts of sodium butyrate, 10 parts of citric acid, compound nitrophenol 12 parts of sodium, 10 parts of magnesium sulfate, 8 parts of potassium dihydrogen phosphate, 35 parts of glucose;By above-mentioned raw materials at normal temperature through double-shaft paddle mixer It is stirred 30 minutes, 50 revs/min of revolving speed, is packaged into the 500g/ bags of synergist to get lactic acid bacteria.The synergist is powder Last shape.
The sodium butyrate: white powder has the special rancid sample smell of cheese, and it is micro- that enteron aisle is adjusted in a kind of acidulant The ecological balance.
The citric acid: a kind of organic acid, it is soluble easily in water, it can promote absorption of the aquiculture animal to minerals.
The compound sodium nitrophenolate: being a kind of strength cell-activating agent, can penetrate into plant rapidly with after plant contact, promotees Plasm into cell flows, and improves cell viability, can promote the growth of water plant.
The magnesium sulfate: it is a kind of compound containing magnesium, can promote the photosynthesis of water plant, or the life of lactic acid bacteria It is long that magnesium elements are provided.
The potassium dihydrogen phosphate: a kind of chemicals, chemical formula KH2PO4.Rich in P elements and potassium element, water can promote Grass growth, can also provide nutrition for lactobacter growth.
The glucose: it is a kind of most wide and mostly important monosaccharide of distributed in nature, carbon can be provided for lactobacter growth Source.
The lactic acid bacteria: lactobacillus acidophilus, bacterium numbering AS1.2686.
Embodiment 2
A kind of synergist of lactic acid bacteria, formula rate are as follows by weight: 30 parts of sodium butyrate, 15 parts of citric acid, compound nitrophenol 15 parts of sodium, 8 parts of magnesium sulfate, 12 parts of potassium dihydrogen phosphate, 20 parts of glucose;By above-mentioned raw materials at normal temperature through double-shaft paddle mixer It is stirred 40 minutes, 40 revs/min of revolving speed, is packaged into the 500g/ bags of synergist to get lactic acid bacteria.
Embodiment 3
A kind of synergist of lactic acid bacteria, formula rate are as follows by weight: 40 parts of sodium butyrate, 6 parts of citric acid, compound sodium nitrophenolate 8 parts, 12 parts of magnesium sulfate, 9 parts of potassium dihydrogen phosphate, 25 parts of glucose;Above-mentioned raw materials are stirred through double-shaft paddle mixer at normal temperature Mixing 35 minutes is mixed, 25 revs/min of revolving speed, is packaged into the 500g/ bags of synergist to get lactic acid bacteria.
Application Example 1
The synergist that embodiment 1 prepares gained lactic acid bacteria is used on one 10 mu of crab pool of Changzhou academic circle, using in preceding pond Water plant root blacks a little, and a small amount of river crab has enteritis phenomenon, uses by 250g/ mus of cooperation lactic acid bacterias, synergist, lactic acid bacteria, water The weight ratio of three presses 1:1:100, and dissolution is sufficiently mixed in bucket or cabin after ten minutes, full pool spilling head, and use is big two days later Amount water plant has tender shoots to grow, and river crab enteron aisle is full, and intestinal flora is normal.

Claims (6)

1. a kind of synergist of lactic acid bacteria, it is characterized in that: formula rate is as follows by weight: 25-45 parts of sodium butyrate, citric acid 5-15 parts, 1-15 parts of compound sodium nitrophenolate, 1-15 parts of magnesium sulfate, 1-15 parts of potassium dihydrogen phosphate, 10-35 parts of glucose;By above-mentioned raw materials It is uniformly mixed at normal temperature through double-shaft paddle mixer, incorporation time: 30-60 minutes, mixing revolving speed: 20-60 revs/min Clock is packaged into the 500g/ bags of synergist to get lactic acid bacteria.
2. a kind of synergist of lactic acid bacteria as described in claim 1, it is characterized in that: formula rate is as follows by weight: fourth 25 parts of sour sodium, 10 parts of citric acid, 12 parts of compound sodium nitrophenolate, 10 parts of magnesium sulfate, 8 parts of potassium dihydrogen phosphate, 35 parts of glucose;By above-mentioned original Material is uniformly mixed through double-shaft paddle mixer at normal temperature, incorporation time: 30 minutes, being mixed revolving speed: 50 revs/min, being wrapped Dress up the 500g/ bags of synergist to get lactic acid bacteria.
3. a kind of synergist of lactic acid bacteria as described in claim 1, it is characterized in that: formula rate is as follows by weight: fourth 30 parts of sour sodium, 15 parts of citric acid, 15 parts of compound sodium nitrophenolate, 8 parts of magnesium sulfate, 12 parts of potassium dihydrogen phosphate, 20 parts of glucose;By above-mentioned original Material is uniformly mixed through double-shaft paddle mixer at normal temperature, incorporation time: 40 minutes, being mixed revolving speed: 40 revs/min, being wrapped Dress up the 500g/ bags of synergist to get lactic acid bacteria.
4. a kind of synergist of lactic acid bacteria as described in claim 1, it is characterized in that: formula rate is as follows by weight: fourth 40 parts of sour sodium, 6 parts of citric acid, 8 parts of compound sodium nitrophenolate, 12 parts of magnesium sulfate, 9 parts of potassium dihydrogen phosphate, 25 parts of glucose;By above-mentioned raw materials It is uniformly mixed at normal temperature through double-shaft paddle mixer, incorporation time: 35 minutes, mixing revolving speed: 25 revs/min, packing At the 500g/ bags of synergist to get lactic acid bacteria.
5. a kind of synergist of lactic acid bacteria as described in claim 1, it is characterized in that: the synergist is powdered.
6. a kind of application of the synergist of lactic acid bacteria makes it is characterized in that: the synergist of preparation gained lactic acid bacteria is used on the crab pool Blacked a little with the water plant root in preceding pond, a small amount of river crab has enteritis phenomenon, uses by 250g/ mus of cooperation lactic acid bacterias, synergy Agent, lactic acid bacteria, water three weight ratio press 1:1:100, be sufficiently mixed in bucket or cabin dissolution after ten minutes, full pool spilling head, There is tender shoots to grow using a large amount of water plants two days later, river crab enteron aisle is full, and intestinal flora is normal.
CN201910648602.0A 2019-07-18 2019-07-18 A kind of synergist of lactic acid bacteria and its application Withdrawn CN110384111A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114190307A (en) * 2021-11-25 2022-03-18 中国水产科学研究院黄海水产研究所 Cynoglossus semilaevis circulating water culture enteritis prevention and treatment method

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CN104705530A (en) * 2015-04-10 2015-06-17 宁国市金东坊农业开发有限公司 Ecological culture method of bait for brevifilis fry
CN104770596A (en) * 2015-04-07 2015-07-15 中国水产科学研究院珠江水产研究所 Aquatic animal intestinal regulator and application thereof
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CN109097306A (en) * 2018-08-30 2018-12-28 湛江恒兴养殖技术服务有限公司 Lactic acid bacteria growth-promoting agent and its preparation method and application

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104770596A (en) * 2015-04-07 2015-07-15 中国水产科学研究院珠江水产研究所 Aquatic animal intestinal regulator and application thereof
CN104705530A (en) * 2015-04-10 2015-06-17 宁国市金东坊农业开发有限公司 Ecological culture method of bait for brevifilis fry
CN107739102A (en) * 2017-10-17 2018-02-27 江苏农牧科技职业学院 A kind of improver of water quality of aquaculture
CN109097306A (en) * 2018-08-30 2018-12-28 湛江恒兴养殖技术服务有限公司 Lactic acid bacteria growth-promoting agent and its preparation method and application

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Title
田莉: "丁酸钠对草鱼肠道、鳃和机体健康及肌肉品质的作用及其机制", 《中国优秀硕士学位论文全文数据库 农业科技辑》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114190307A (en) * 2021-11-25 2022-03-18 中国水产科学研究院黄海水产研究所 Cynoglossus semilaevis circulating water culture enteritis prevention and treatment method

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