CN110291109A - 人程序性死亡受体pd-1的单克隆抗体及其片段 - Google Patents

人程序性死亡受体pd-1的单克隆抗体及其片段 Download PDF

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CN110291109A
CN110291109A CN201880002948.7A CN201880002948A CN110291109A CN 110291109 A CN110291109 A CN 110291109A CN 201880002948 A CN201880002948 A CN 201880002948A CN 110291109 A CN110291109 A CN 110291109A
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antibody
seq
antigen
binding fragment
amino acid
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CN110291109B (zh
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陈列平
罗利群
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Tayu Huaxia Biotech Medical Group Co ltd
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    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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Abstract

本发明提供了针对人PD‑1的分离的单克隆抗体或其抗原结合片段，包含表2中所列的重链CDR1、CDR2和CDR3以及表2中所列的轻链CDR1、CDR2和CDR3。

Description

PCT国内申请，说明书已公开。

Claims (21)

  1. PCT国内申请，权利要求书已公开。
CN201880002948.7A 2017-01-20 2018-01-19 人程序性死亡受体pd-1的单克隆抗体及其片段 Active CN110291109B (zh)

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CN201710046148 2017-01-20
CN2017100461482 2017-01-20
PCT/CN2018/073437 WO2018133842A1 (zh) 2017-01-20 2018-01-19 人程序性死亡受体pd-1的单克隆抗体及其片段

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CN202311368997.1A Pending CN117586401A (zh) 2017-01-20 2018-01-19 抗pd-1抗体及其用途
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EP (1) EP3571231A4 (zh)
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AU (1) AU2018209556C1 (zh)
BR (1) BR112019013238A2 (zh)
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CN116589572A (zh) * 2023-06-28 2023-08-15 湖南诺合新生物科技有限公司 一种抗ha标签的单克隆抗体及其应用

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CN110291109B (zh) 2017-01-20 2023-01-31 大有华夏生物医药集团有限公司 人程序性死亡受体pd-1的单克隆抗体及其片段
TWI806870B (zh) * 2018-05-23 2023-07-01 中國大陸商大有華夏生物醫藥集團有限公司 抗pd-1抗體及其用途
AU2019275737A1 (en) 2018-06-01 2021-01-21 Tayu Huaxia Biotech Medical Group Co., Ltd. Compositions and uses thereof for treating disease or condition
CN112424231B (zh) * 2018-07-19 2022-09-13 大有华夏生物医药集团有限公司 抗pd-1抗体及其剂量和用途
CN110845614A (zh) * 2018-08-21 2020-02-28 大有华夏生物医药集团有限公司 人细胞表面免疫调节分子
CN109053895B (zh) * 2018-08-30 2020-06-09 中山康方生物医药有限公司 抗pd-1-抗vegfa的双功能抗体、其药物组合物及其用途
WO2020063823A1 (en) * 2018-09-27 2020-04-02 Zai Lab (Shanghai) Co., Ltd. Anti-pd-1 antibodies and uses thereof
WO2020132583A1 (en) * 2018-12-21 2020-06-25 Gloriana Therapeutics Sarl Mammalian cell culture-produced neublastin antibodies
CA3128104A1 (en) * 2019-02-03 2020-08-06 Jiangsu Hengrui Medicine Co., Ltd. Anti-pd-1 antibody, antigen-binding fragment thereof and pharmaceutical use thereof
EP3998287A4 (en) * 2019-07-08 2023-08-09 Nanjing GenScript Biotech Co., Ltd. ANTI-CD47/ANTI-PD-1 BISPECIFIC ANTIBODY, METHOD FOR ITS PRODUCTION AND ITS USE
TW202112825A (zh) * 2019-09-06 2021-04-01 大陸商北京拓界生物醫藥科技有限公司 抗ｐｄ－１單域抗體、其衍生蛋白及其醫藥用途
CN116529260A (zh) 2020-06-02 2023-08-01 当康生物技术有限责任公司 抗cd93构建体及其用途
WO2021247769A1 (en) 2020-06-02 2021-12-09 Dynamicure Biotechnology Llc Anti-cd93 constructs and uses thereof
AU2021315665A1 (en) 2020-07-29 2023-03-16 Dynamicure Biotechnology Llc Anti-CD93 constructs and uses thereof
JP2023553157A (ja) * 2020-12-10 2023-12-20 ユーティレックス カンパニー リミテッド 抗－ｐｄ－１抗体およびその用途
EP4314049A1 (en) 2021-03-25 2024-02-07 Dynamicure Biotechnology LLC Anti-igfbp7 constructs and uses thereof
CN115521379B (zh) * 2021-07-16 2023-12-22 南京吉盛澳玛生物医药有限公司 Pd-1抗体及其用途

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