CN110279617A - A kind of shampoo and preparation method thereof containing fiery numb essential oil - Google Patents

A kind of shampoo and preparation method thereof containing fiery numb essential oil Download PDF

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Publication number
CN110279617A
CN110279617A CN201910715863.XA CN201910715863A CN110279617A CN 110279617 A CN110279617 A CN 110279617A CN 201910715863 A CN201910715863 A CN 201910715863A CN 110279617 A CN110279617 A CN 110279617A
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essential oil
preparation
shampoo
cannabidiol
fire
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Inventor
刘胜贵
王钲霖
薛红芬
付彬彬
李智高
孔令羽
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Yunnan Luxin Biopharmaceutical Co Ltd
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Yunnan Luxin Biopharmaceutical Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/347Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/46Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
    • A61K8/466Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/006Antidandruff preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/30Characterized by the absence of a particular group of ingredients
    • A61K2800/34Free of silicones

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of shampoos and preparation method thereof containing fiery numb essential oil.The shampoo includes following raw material: rich in cannabidiol (CBD) fire numb essential oil, surfactant, conditioner, thickener, pearling agent, chelating agent, essence, preservative, deionized water.The numb essential oil of fire of the present invention is formulated by cannabidiol and fiery sesame oil, fiery sesame oil not only has the function of moist moisturizing, the cannabidiol for being practically insoluble in water can also be made sufficiently to dissolve wherein, to cooperate with performance that product is made to have effects that antibacterial anti-inflammatory, anti-dandruff and itching-relieving, tranquilizing the mind are releived.Silicate-containing oil, fire fiber crops essential oil category pure plant do not extract active constituent to this product, and safety is mild non-stimulated, meets green and healthy environmental protection concept.

Description

A kind of shampoo and preparation method thereof containing fiery numb essential oil
Technical field
The invention belongs to daily chemicals fields, are related to a kind of hair shampoo article, and in particular to a kind of shampoo containing fiery numb essential oil and Preparation method.
Background technique
Shampoo is the indispensable daily necessity of people's daily life, with the improvement of living standards, people are to health Safety is increasingly paid attention to, for the different demand of further satisfaction consumer and the development trend of product function diversification, Biologically active natural products is added in shampoo basic components, is the important directions for developing specific function product.
Dandruff is due to caused by scalp functional disturbance, is the product of metabolism, and Recent study shows dandruff mistake Abnormality proliferation mostly with scalp itch and Pityrosporum ovale has substantial connection.The growth for being produced as microorganism of dandruff and Breeding creates advantage and leads to stimulate scalp, causes itch, accelerates the abnormality proliferation of epidermal cell.Therefore, inhibit thin Born of the same parents' angling speed, thus reduce epidermis metabolism speed and sterilization be anti-antidandruff main path.At present in shampoo Anti-dandruff and itching-relieving agent be mainly chemical synthesis, such as climbazole, zinc pyrithione, ketoconazole, be used for a long time to human health not Benefit.
Though hemp is acknowledged as one of big drugs in the world three, due to the valuable pharmacological and physiology of its active constituent cannboid Activity and increasingly paid attention to by common people, separated more than 100 kinds plant-derived cannboids so far.And content is more in cannboid Cannabidiol (CBD) due to its unique antibacterial, anti-inflammatory, it is anti-oxidant and to the repairs of damaging cells increasingly by people Attention.
Fiery sesame oil is the oily mixture that fructus cannabis is extracted by techniques such as low-temperature cold pressing, subcritical low-temperature extractions, is The oil plant of water can be uniquely dissolved in.Fiery flaxseed oil is full of nutrition, containing antioxidant, protein, carrotene, phytosterol, Phosphatide and several mineral materials and a high proportion of essential fatty acid, have anti-inflammatory, anti-agings, moisten moisturizing, handle skin infection, Skin injury and anti-oxidation efficacy are cured in help.
Patent CN109806203A discloses a kind of shampoo of extract of floral leaf containing industrial hemp, and main component is big Numb diphenol, the invention is by the way that Cannador to be directly formulated with other basic components by a certain percentage, to play big The effect of nettle extract.But since cannabidiol belongs to fat-soluble compound, it is practically insoluble in water, and big portion in shampoo formula Dividing is water, and directly addition Cannador or cannabidiol can all reduce the solubility of effective component into shampoo formula, from And be not easy to be absorbed by the skin, cause bioavailability to be greatly reduced, its effect cannot be given full play to.By hemp two in the present invention The numb essential oil of fire obtained by phenol and the numb essential oil of fire are prepared can improve the solubility of cannabidiol but collaboration play fire fiber crops essential oil with The many physiological effects of cannabidiol, the effect of really playing inhibiting bacteria and diminishing inflammation, anti-dandruff and itching-relieving.
Summary of the invention
In view of the above problems and consumer demand, in conjunction with cannabidiol and the unique physiological function of the numb essential oil of fire, By improving the solubility of cannabidiol, and then its bioavailability is improved, the present invention provides a kind of washing containing fiery numb essential oil Shampoo and preparation method thereof, this product can be effectively suppressed bacteria breed, reduce dandruff generation, alleviate itching of the scalp, institute of the present invention Shampoo not silicate-containing oil is stated, it is healthy and safe, it is mild non-stimulated.
To achieve the above object, the invention adopts the following technical scheme:
(1) a kind of shampoo and preparation method thereof containing fiery numb essential oil, is made of: 0.1%-5% the raw material of following weight percent Fiery fiber crops essential oil, 10%-30% surfactant, 0.1%-5% conditioner, 0.1%-3% thickener, 0.01%-1% chelating agent, 0.1%-3% Pearling agent, 0.01%-1% essence, 0.001%-0.1% preservative, surplus are deionized water.
Further, the surfactant is sodium lauroyl sarcosine, sodium lauroyl glutamate, methyl cocoyl ox At least one of sodium sulfonate, cocaminopropionic acid sodium.
Further, the conditioner is Polyquaternium-10, polyquaternium -52, cation guar gum.
Further, the thickener is one or more of sodium chloride, ammonium chloride mixture.
Further, the chelating agent is disodium ethylene diamine tetraacetate, tetrasodium ethylenediamine tetraacetate, citric acid, tartaric acid One or more of mixture.
Further, the pearling agent is one or more of ethylene glycol monostearate, ethylene glycol double stearate Mixture.
Further, the preservative is one or both of sodium benzoate, benzene oxygen second mixture.
Further, the essence is conventional daily chemical essence in the prior art, according to the different odor type demand of product into Row addition, the present invention are not specifically limited in this embodiment.
(2) method for preparing the numb essential oil shampoo of fire using above-mentioned raw materials, comprising the following steps:
Step 1: deionized water, chelating agent, conditioner are added in reactor, stir to being completely dissolved, obtain solution A.
Step 2: solution A is heated to 70-90 DEG C, surfactant and pearling agent is added, stirs to being completely dissolved, obtains Solution B.
Step 3: being cooled to 30-50 DEG C to solution B, fiery numb essential oil, thickener, essence, preservative are sequentially added, completely It is stirred evenly after dissolution, the pH value of solution is adjusted to 5.5-7.0 with citric acid.
Step 4: stand defoams product up to the shampoo finished product more than for 24 hours.
(3) preparation method of the numb essential oil of the fire, by cannabidiol crystal (99% or more purity) with fiery sesame oil according to certain Ratio be mixed, be completely dissolved to cannabidiol to get fiery numb essential oil.
(4) content of cannabidiol is 5~60% in the numb essential oil of the fire.
Beneficial effects of the present invention:
1, cannabidiol is practically insoluble in water, and direct use can reduce its bioavailability, is unfavorable for absorption of human body.This is bad Characteristic limits promoting the use for cannabidiol, and influences its effect.Cannabidiol and fiery sesame oil belong to industrial hemp processing and produce Cannabidiol is dissolved in fiery sesame oil by product, so that cannabidiol molecule is dispersed in fiery sesame oil, not only increases the molten of cannabidiol Xie Du, and there is synergistic effect.
2, the numb essential oil hair washing water energy of fire of the present invention effectively inhibits bacteria breed, there is preferable anti-inflammatory and anti-dandruff and itching-relieving The effect of, fire fiber crops essential oil is the main composition of this product anti-dandruff and itching-relieving, belongs to pure plant additive, safe and healthy.
3, silicate-containing oil, surfactant used are not amino acid pattern to shampoo of the present invention, are acted on hair and skin Mildly, it protects hair quality not to be damaged, and degradable, meets the theory of green and healthy environmental protection.
Specific embodiment
The present invention is further explained in the light of specific embodiments, but not limited to the examples.
Embodiment 1
(1) preparation of the numb essential oil of fire
6 grams of cannabidiol solid powders are added in 94 grams of fiery sesame oil, are sufficiently stirred, dissolve solid sufficiently to get containing hemp The numb essential oil of the fire of diphenol 6%.
(2) a kind of preparation method containing fiery numb essential oil shampoo, includes the following steps:
Step 1: 100 grams of products of preparation, weigh 40 grams of deionized waters, 0.01 gram of EDTA-2Na, 0.1 gram of Polyquaternium-10,0.1 Gram polyquaternium -52 is added in reactor, is stirred to being completely dissolved, is obtained solution A.
Step 2: solution A is heated to 70 DEG C, 5 grams of sodium lauroyl sarcosines, 5 grams of sodium lauroyl glutamates, 0.1 are added Gram ethylene glycol double stearate stirs to being completely dissolved, obtains solution B.
Step 3: be cooled to 50 DEG C to solution B, sequentially add the numb essential oils of 5 grams of fire, 3 grams of sodium chloride, 1 gram of Rosa Damascana, 0.001 gram of Phenoxyethanol, 0.001 gram of sodium benzoate, stir evenly after being completely dissolved, and are adjusted to the pH value of solution with citric acid 5.5。
Step 4: stand defoams product up to the shampoo finished product more than for 24 hours.
Embodiment 2
(1) preparation of the numb essential oil of fire
15 grams of cannabidiol solid powders are added in 85 grams of fiery sesame oil, are sufficiently stirred, dissolve solid sufficiently to get containing hemp The numb essential oil of the fire of diphenol 15%.
(2) a kind of preparation method containing fiery numb essential oil shampoo, includes the following steps:
Step 1: 100 grams of products of preparation, weigh 40 grams of deionized waters, 0.1 gram of EDTA-2Na, 1 gram of Polyquaternium-10,0.5 gram Cation guar gum is added in reactor, is stirred to being completely dissolved, is obtained solution A.
Step 2: solution A is heated to 75 DEG C, be added 10 grams of sodium lauroyl sarcosines, 5 grams of cocaminopropionic acid sodium, 0.5 gram of ethylene glycol monostearate stirs to being completely dissolved, obtains solution B.
Step 3: being cooled to 45 DEG C to solution B, 4 grams of fire numb essential oil, 2 grams of sodium chloride, 0.5 gram of lavender essence are sequentially added Oil, 0.005 gram of Phenoxyethanol, stir evenly after being completely dissolved, the pH value of solution are adjusted to 6.0 with citric acid.
Step 4: stand defoams product up to the shampoo finished product more than for 24 hours.
Embodiment 3
(1) preparation of the numb essential oil of fire
30 grams of cannabidiol solid powders are added in 70 grams of fiery sesame oil, are sufficiently stirred, dissolve solid sufficiently to get containing hemp The numb essential oil of the fire of diphenol 30%.
(2) a kind of preparation method containing fiery numb essential oil shampoo, includes the following steps:
Step 1: 100 grams of products of preparation, weigh 40 grams of deionized waters, 0.5 gram of EDTA-4Na, 2 grams of polyquaterniums -52,2 grams of sun Cationic guar is added in reactor, is stirred to being completely dissolved, is obtained solution A.
Step 2: solution A is heated to 80 DEG C, 15 grams of sodium lauroyl glutamates, 5 grams of methyl cocoyl taurines are added Sodium, 5 grams of cocaminopropionic acid sodium, 1 gram of ethylene glycol monostearate, 1 ethylene glycol double stearate, stirring to being completely dissolved, Obtain solution B.
Step 3: be cooled to 40 DEG C to solution B, sequentially add the numb essential oils of 3 grams of fire, 1 gram of sodium chloride, 0.5 gram of refined jasmine oil, 0.01 gram of sodium benzoate, stirs evenly after being completely dissolved, and the pH value of solution is adjusted to 6.5 with citric acid.
Step 4: stand defoams product up to the shampoo finished product more than for 24 hours.
Embodiment 4
(1) preparation of the numb essential oil of fire
50 grams of cannabidiol solid powders are added in 50 grams of fiery sesame oil, are sufficiently stirred, dissolve solid sufficiently to get containing hemp The numb essential oil of the fire of diphenol 50%.
(2) a kind of preparation method containing fiery numb essential oil shampoo, includes the following steps:
Step 1: 100 grams of products of preparation, weigh 40 grams of deionized waters, 1 gram of EDTA-2Na, 1.5 grams of polyquaterniums -52,1.5 grams Polyquaternium-10,2 grams of cation guar gums are added in reactor, are stirred to being completely dissolved, are obtained solution A.
Step 2: solution A is heated to 85 DEG C, 15 grams of sodium lauroyl sarcosines, 10 grams of sodium lauroyl glutamates, 5 are added Gram sodium methyl cocoyl taurate, 3 grams of ethylene glycol monostearates stir to being completely dissolved, obtain solution B.
Step 3: being cooled to 35 DEG C to solution B, 1.5 grams of fire numb essential oil, 0.1 gram of ammonium chloride, 0.1 gram of rose are sequentially added Essential oil, 0.1 gram of sodium benzoate, stir evenly after being completely dissolved, and the pH value of solution is adjusted to 6.0 with citric acid.
Step 4: stand defoams product up to the shampoo finished product more than for 24 hours.
Embodiment 5
(1) preparation of the numb essential oil of fire
60 grams of cannabidiol solid powders are added in 40 grams of fiery sesame oil, are sufficiently stirred, dissolve solid sufficiently to get containing hemp The numb essential oil of the fire of diphenol 60%.
(2) a kind of preparation method containing fiery numb essential oil shampoo, includes the following steps:
Step 1: 100 grams of products of preparation, weigh 40 grams of deionized waters, 0.8 gram of EDTA-2Na, 5 grams of Polyquaternium-10s and are added to In reactor, stirs to being completely dissolved, obtain solution A.
Step 2: solution A is heated to 90 DEG C, 30 grams of sodium lauroyl glutamates, 1 gram of ethylene glycol double stearate are added, Stirring obtains solution B to being completely dissolved.
Step 3: be cooled to 30 DEG C to solution B, sequentially add the numb essential oil of 0.5 gram of fire, 0.5 gram of sodium chloride, 0.01 gram smoke clothing Careless essential oil, 0.1 gram of Phenoxyethanol, stir evenly after being completely dissolved, and the pH value of solution is adjusted to 7.0 with citric acid.
Step 4: stand defoams product up to the shampoo finished product more than for 24 hours.
The foregoing is merely the schematical specific embodiments of the present invention, are not intended to limit the scope of the present invention. To those skilled in the art, it is all without departing from same embodiment made by the technology of the present invention spirit or change in this hair Within bright protection scope.

Claims (6)

1. a kind of shampoo and preparation method thereof containing fiery numb essential oil, the shampoo by following weight percent raw material group At: 0.1%-5% increases rich in the numb essential oil of cannabidiol (CBD) fire, 10%-30% surfactant, 0.1%-5% conditioner, 0.1%-3% Thick dose, 0.01%-1% chelating agent, 0.1%-3% pearling agent, 0.01%-1% essence, 0.001%-0.1% preservative, surplus is deionization Water.
2. a kind of shampoo and preparation method thereof containing fiery numb essential oil according to claim 1, which is characterized in that the table Face activating agent is sodium lauroyl sarcosine, sodium lauroyl glutamate, sodium methyl cocoyl taurate, cocaminopropionic acid sodium In one or more mixtures;The conditioner be one of Polyquaternium-10, polyquaternium -52, cation guar gum or A variety of mixtures;The thickener is one or both of sodium chloride, ammonium chloride mixture;The pearling agent is ethylene glycol list One or both of stearate, ethylene glycol double stearate mixture;The chelating agent is disodium ethylene diamine tetraacetate, second One or more of one or more of four sodium of ethylenediamine tetraacetic acid (EDTA), citric acid, tartaric acid mixture mixture;The anti-corrosion Agent is one or both of sodium benzoate, Phenoxyethanol mixture.
3. a kind of shampoo and preparation method thereof containing fiery numb essential oil according to claim 1 or 2, which is characterized in that institute The method of stating includes the following steps:
Deionized water, chelating agent, conditioner are added in reactor, stirs to being completely dissolved, obtains solution A;
Solution A is heated to 70-90 DEG C, sequentially adds surfactant, pearling agent, stirs to being completely dissolved, obtains solution B;
Be cooled to 30-50 DEG C to solution B, sequentially add fiery numb essential oil, thickener, essence, preservative, stirring to being completely dissolved, The pH value of solution is adjusted to 5.5-7.0 with citric acid;
Stand defoams product up to the shampoo finished product more than for 24 hours.
4. a kind of shampoo and preparation method thereof containing fiery numb essential oil according to claim 1, which is characterized in that the fire The preparation method of numb essential oil: cannabidiol crystal and fiery sesame oil are mixed according to a certain percentage, complete to cannabidiol Dissolution is to get fiery numb essential oil.
5. the preparation method of the numb essential oil of fire according to claim 4, which is characterized in that the cannabidiol crystal purity is wanted Ask 99% or more.
6. the preparation method of the numb essential oil of fire according to claim 4, which is characterized in that cannabidiol in the numb essential oil of fire Content be 5~60%.
CN201910715863.XA 2019-08-05 2019-08-05 A kind of shampoo and preparation method thereof containing fiery numb essential oil Withdrawn CN110279617A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110973159A (en) * 2019-10-30 2020-04-10 广州市浪奇实业股份有限公司 Antibacterial composition containing cannabidiol and application thereof
WO2021123804A1 (en) * 2019-12-19 2021-06-24 GW Research Limited Oral cannabinoid formulations

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110973159A (en) * 2019-10-30 2020-04-10 广州市浪奇实业股份有限公司 Antibacterial composition containing cannabidiol and application thereof
CN110973159B (en) * 2019-10-30 2021-04-06 广州市浪奇实业股份有限公司 Antibacterial composition containing cannabidiol and application thereof
WO2021123804A1 (en) * 2019-12-19 2021-06-24 GW Research Limited Oral cannabinoid formulations

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