CN110269822B - Salmon proteoglycan moisturizing skin care emulsion and preparation method and application thereof - Google Patents
Salmon proteoglycan moisturizing skin care emulsion and preparation method and application thereof Download PDFInfo
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Abstract
The invention discloses a salmon proteoglycan moisturizing skin care emulsion and a preparation method and application thereof, wherein the salmon proteoglycan moisturizing skin care emulsion is prepared from the following raw materials in percentage by mass: 5-10% of liquid paraffin, 5-10% of caprylic triglyceride and 5-10% of coconut oil; phase B: 0.1-0.2% of carbomer, 0.05-2% of polyglutamic acid, 5-15% of butanediol, 5-15% of glycerol and 1-5% of xanthan gum; and C phase: salmon proteoglycan 0.5-2%, bacillus prodigiosus nuclease 0.01-0.05%, honeysuckle flower distillate 5-20%, surfactant 1-5%, and pH regulator 0.01-5%; the balance being deionized water. The advantages of the salmon proteoglycan, the honeysuckle dew, the polyglutamic acid extract and other pure natural products are reasonably prepared according to the proportion, and the pure natural skin-care moisturizing emulsion without heavy metal addition and side effects is produced, so that the skin metabolism can be effectively improved, the effects of moisturizing and whitening the skin, improving the elasticity of the skin, removing wrinkles and the like are facilitated.
Description
Technical Field
The invention belongs to the field of daily chemical products, relates to a nutritional skin care emulsion containing salmon proteoglycan and bacillus prodigiosus nuclease, and a preparation method and application thereof, and particularly relates to a salmon proteoglycan moisturizing skin care emulsion, and a preparation method and application thereof.
Background
At present, as the living conditions of human beings are continuously improved, more and more people begin to use skin care products. The skin care products on the market are various and uneven, a large amount of chemical components such as heavy metals, preservatives and the like are contained in a large amount of emulsion, a certain stimulation effect is generated on facial skin, and the skin care products cannot play a role in skin care and can cause skin allergy, skin relaxation and the like after being used for a long time. Aiming at the problem, the development of a green and healthy moisturizing skin care product without chemical addition is the key point of cosmetic research, but the moisturizing skin care product without chemical addition in the prior art often has the problems of unobvious or no effect of matching use, and some or even side effects due to the interaction between different components, and the problem is a technical problem of limiting the development of the green and healthy moisturizing skin care product.
Disclosure of Invention
In order to solve the technical problems in the prior art, one of the purposes of the invention is to provide a salmon proteoglycan moisturizing skin care emulsion, the components selected in the emulsion have synergistic interaction, the original single-component effect is maintained, the effect of the obtained skin care emulsion is remarkably improved compared with the effect of the single component after the components are matched according to the dosage of the invention, the skin metabolism is effectively improved, the skin moisturizing and whitening are facilitated, the skin elasticity is improved, and the effects of wrinkle removal and the like are achieved.
The technical scheme adopted by the invention is as follows:
the salmon proteoglycan moisturizing skin-care emulsion is prepared from the following raw materials in percentage by mass: 5-10% of liquid paraffin, 5-10% of caprylic triglyceride and 5-10% of coconut oil; phase B: 0.1-0.2% of carbomer, 0.05-2% of polyglutamic acid, 5-15% of butanediol, 5-15% of glycerol and 1-5% of xanthan gum; and C phase: salmon proteoglycan 0.5-2%, bacillus prodigiosus nuclease 0.01-0.05%, honeysuckle flower distillate 5-20%, surfactant 1-5%, and pH regulator 0.01-5%; the balance being deionized water.
Preferably: the salmon proteoglycan moisturizing skin-care emulsion is prepared from the following raw materials in percentage by mass: 7-9% of liquid paraffin, 6-8% of caprylic triglyceride and 6-8% of coconut oil; phase B: 0.1-0.2% of carbomer, 1-1.5% of polyglutamic acid, 8-10% of butanediol, 8-10% of glycerol and 2-3% of xanthan gum; and C phase: 1-1.5% of salmon proteoglycan, 0.01-0.03% of bacillus prodigiosus nuclease, 8-15% of honeysuckle flower distillate, 1-3% of surfactant and 2-3% of pH regulator; the balance being deionized water.
Preferably: the salmon proteoglycan moisturizing skin-care emulsion is prepared from the following raw materials in percentage by mass: 8% of liquid paraffin, 7% of caprylic triglyceride and 9% of coconut oil; phase B: 0.15% of carbomer, 1% of polyglutamic acid, 10% of butanediol, 10% of glycerol and 3% of xanthan gum; and C phase: 1% of salmon proteoglycan, 0.02% of bacillus prodigiosus nuclease, 15% of honeysuckle flower distillate, 3% of surfactant and 3% of pH regulator; the balance being deionized water.
Preferably: the surfactant is selected from sorbitan fatty acid ester or sodium lauroyl sarcosinate; the pH regulator is selected from sodium hydroxide or arginine.
The invention also aims to provide a preparation method of the salmon proteoglycan moisturizing and skin-protecting emulsion, which comprises the following steps:
(1) heating phase A to 70-80 deg.C, stirring, and keeping the temperature for 15-60 min;
(2) adding other raw materials of the phase B after the phase B carbomer and the water are fully hydrated, heating to 70-80 ℃, uniformly stirring, and preserving heat for 15-60 minutes for later use;
(3) homogenizing the phase B by 2000-4000rmp, adding the phase A into the phase B, and homogenizing for 5-10 min; stirring at 20-60rpm, cooling to 40-50 deg.C, adding pH regulator in phase C, and stirring;
(4) stirring at 20-60rpm, cooling to below 37 deg.C, adding salmon proteoglycan, Bacillus prodigiosus nuclease and flos Lonicerae distillate from C phase, and stirring at 20-60rpm to obtain the final product.
Preferably: a preparation method of the salmon proteoglycan moisturizing skin care emulsion comprises the following steps:
(1) heating phase A to 75 deg.C, stirring, and keeping the temperature for 45 min;
(2) adding other raw materials of the phase B after the phase B carbomer and the water are fully dispersed and hydrated, heating to 75 ℃, uniformly stirring, and preserving heat for 40 minutes for later use;
(3) homogenizing phase B at 3000rmp for 8min, adding phase A into phase B; stirring at 40rpm, cooling to 45 deg.C, adding pH regulator in phase C, and stirring;
(4) stirring at 45rpm, cooling to below 37 deg.C, adding salmon proteoglycan, Bacillus prodigiosus nuclease, flos Lonicerae distillate and polyglutamic acid in phase C, and stirring at 40 rpm.
The invention also aims to protect the moisturizing and skin-care emulsion prepared by the preparation method.
The fourth purpose of the invention is to protect the application of the moisturizing and skin-care emulsion in preparing other cosmetics.
The fifth purpose of the invention is to protect the application of the moisturizing and skin-care emulsion in preparing the moisturizing and whitening cosmetics.
The invention also aims to protect the application of the moisturizing and skin-care emulsion in preparing cosmetics for improving the elasticity of skin.
The invention also aims to protect the application of the moisturizing and skin-care emulsion in preparing the wrinkle-removing cosmetic.
The salmon proteoglycan adopted by the invention is soluble natural macromolecular substances extracted from salmon nasal cartilage. Salmon proteoglycan has the effect of promoting epidermal cell growth, has the similar effect to EGF, and can promote cell growth, improve rough skin, and promote collagen production. Salmon is a general name of three major types of salmon, trout and salmon. Salmon is a popular food and is also a very healthy food. The salmon contains rich unsaturated fatty acid, can effectively reduce blood fat and blood cholesterol, and prevent and treat cardiovascular diseases, contains omega-3 fatty acid which is essential substance for brain, retina and nervous system, and has effects of enhancing brain function, preventing and treating senile dementia and preventing hypopsia. Can effectively prevent the occurrence and development of chronic diseases such as diabetes and the like, has high nutritional value and enjoys the reputation of 'aquatic treasure'.
The ganoderma nuclease is a non-restrictive broad-spectrum nuclease derived from Serratia marcescens (also called ganoderma), can cut any nucleotide in a nucleic acid chain, and can cut any form of nucleic acid (single-stranded, double-stranded, linear, circular or supercoiled DNA or RNA). The enzyme cutting efficiency is far higher than other nucleases, the activity is 34 times of that of bovine pancreas DNase I and 6 times of that of staphylococcus aureus nuclease. In the vaccine industry and the protein and polysaccharide industry, the use of the bacillus prodigiosus nuclease can reduce the nucleic acid pollution in the product to picogram level. The Salmon proteoglycan moisturizing skin care emulsion can be added with Bacillus prodigiosus nuclease to remove virus, and has antiinflammatory effect.
The aqua lonicerae foliae has the functions of whitening, moisturizing, inhibiting bacteria and diminishing inflammation.
Polyglutamic acid (gamma-PGA), also called natto gum and polyglutamic acid, is a biological polymer which is water-soluble, biodegradable and nontoxic and is prepared by a microbial fermentation method. The special molecular structure of the gamma-PGA can effectively increase the moisture retention capacity of the skin and promote the health of the skin. The moisturizing effect of γ -PGA is 2-3 times more than that of Hyaluronic Acid (HA), which is recognized as the most moisturizing ability.
Has the advantages that:
the salmon proteoglycan extracted by combining salmon nasal cartilage, bacillus prodigiosus nuclease, honeysuckle dew, a surfactant, liquid paraffin, caprylic triglyceride, coconut oil, carbomer, polyglutamic acid, butanediol, glycerol, xanthan gum, a pH regulator and deionized water are uniformly mixed. The advantages of salmon proteoglycan, honeysuckle dew, polyglutamic acid extract and other pure natural products are reasonably prepared according to the proportion, and the pure natural skin-care moisturizing emulsion without heavy metal addition and side effects is produced, can effectively improve skin metabolism, is beneficial to moisturizing and whitening skin, improves skin elasticity, removes wrinkles and other effects.
Drawings
FIG. 1 is a graph showing the effect of volunteers in using the emulsion II of the example for 90 days.
Detailed Description
The technical solutions of the present invention will be described clearly and completely with reference to the following embodiments, and it should be understood that the described embodiments are some, but not all, embodiments of the present invention.
All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict.
Example one
The embodiment illustrates a salmon proteoglycan moisturizing skin care emulsion which is prepared from the following raw materials in percentage by mass: 5-10% of liquid paraffin, 5-10% of caprylic triglyceride and 5-10% of coconut oil; phase B: 0.1-0.2% of carbomer, 0.05-2% of polyglutamic acid, 5-15% of butanediol, 5-15% of glycerol and 1-5% of xanthan gum; and C phase: salmon proteoglycan 0.5-2%, bacillus prodigiosus nuclease 0.01-0.05%, honeysuckle flower distillate 5-20%, surfactant 1-5%, and pH regulator 0.01-5%; the balance being deionized water.
The preparation method of the salmon proteoglycan moisturizing and skin-care emulsion in the embodiment comprises the following specific steps:
(1) heating phase A to 70-80 deg.C, stirring, and keeping the temperature for 15-60 min;
(2) adding other raw materials of the phase B after the phase B carbomer and the water are fully hydrated, heating to 70-80 ℃, uniformly stirring, and preserving heat for 15-60 minutes for later use;
(3) homogenizing the phase B by 2000-4000rmp, adding the phase A into the phase B, and homogenizing for 5-10 min; stirring at 20-60rpm, cooling to 40-50 deg.C, adding pH regulator in phase C, and stirring;
(4) stirring at 20-60rpm, cooling to below 37 deg.C, adding salmon proteoglycan, Bacillus prodigiosus nuclease, flos Lonicerae distillate, and polyglutamic acid, and stirring at 20-60 rpm.
Example two
The same technical features in this embodiment as those in the above embodiments are not described in detail, and the technical features of this embodiment different from those in the above embodiments are as follows:
the salmon proteoglycan moisturizing skin-care emulsion is prepared from the following raw materials in percentage by mass: 8% of liquid paraffin, 7% of caprylic triglyceride and 9% of coconut oil; phase B: 0.15% of carbomer, 1% of polyglutamic acid, 10% of butanediol, 10% of glycerol and 3% of xanthan gum; and C phase: 12% of salmon proteoglycan, 0.02% of bacillus prodigiosus nuclease, 15% of honeysuckle flower distillate, 3% of surfactant and 2% of pH regulator; the balance being deionized water.
The preparation method of the salmon proteoglycan moisturizing and skin-care emulsion in the embodiment comprises the following specific steps:
(1) heating phase A to 75 deg.C, stirring, and keeping the temperature for 45 min;
(2) adding other raw materials of the phase B after the phase B carbomer and the water are fully dispersed and hydrated, heating to 75 ℃, uniformly stirring, and preserving heat for 40 minutes for later use;
(3) homogenizing phase B at 3000rmp for 8min, adding phase A into phase B; stirring at 40rpm, cooling to 45 deg.C, adding pH regulator in phase C, and stirring;
(4) stirring at 45rpm, cooling to below 37 deg.C, adding salmon proteoglycan, Bacillus prodigiosus nuclease, flos Lonicerae distillate and polyglutamic acid in phase C, and stirring at 40 rpm.
EXAMPLE III
The same technical features in this embodiment as those in the above embodiments are not described in detail, and the technical features of this embodiment different from those in the above embodiments are as follows:
the embodiment illustrates a salmon proteoglycan moisturizing skin care emulsion which is prepared from the following raw materials in percentage by mass: 5% of liquid paraffin, 10% of caprylic triglyceride and 8% of coconut oil; phase B: carbomer 0.1%, polyglutamic acid 0.05%, butanediol 10%, glycerol 5%, and xanthan gum 3%; and C phase: salmon proteoglycan 0.5%, bacillus prodigiosus nuclease 0.05%, honeysuckle flower distillate 5%, surfactant 1% and pH regulator 0.01%; the balance being deionized water.
The preparation method of the salmon proteoglycan moisturizing and skin-care emulsion in the embodiment comprises the following specific steps:
(1) heating phase A to 80 deg.C, stirring, and keeping the temperature for 15 min;
(2) adding other raw materials of the phase B after the phase B carbomer and the water are fully dispersed and hydrated, heating to 80 ℃, uniformly stirring, and keeping the temperature for 60 minutes for later use;
(3) homogenizing phase B at 4000rmp, adding phase A into phase B, and homogenizing for 10 min; stirring at 60rpm, cooling to 50 ℃, adding the pH regulator in the phase C, and uniformly stirring;
(4) stirring at 60rpm, cooling to below 37 deg.C, adding salmon proteoglycan, Bacillus prodigiosus nuclease, flos Lonicerae distillate and polyglutamic acid, and stirring at 60 rpm.
Example four
The same technical features in this embodiment as those in the above embodiments are not described in detail, and the technical features of this embodiment different from those in the above embodiments are as follows:
the embodiment illustrates a salmon proteoglycan moisturizing skin care emulsion which is prepared from the following raw materials in percentage by mass: 8% of liquid paraffin, 6% of caprylic triglyceride and 5% of coconut oil; phase B: carbomer 0.15%, polyglutamic acid 2%, butanediol 5%, glycerol 10%, and xanthan gum 1%; and C phase: 1% of salmon proteoglycan, 0.01% of bacillus prodigiosus nuclease, 10% of honeysuckle flower distillate, 3% of surfactant and 3% of pH regulator; the balance being deionized water.
The preparation method of the salmon proteoglycan moisturizing and skin-care emulsion in the embodiment comprises the following specific steps:
(1) heating phase A to 70 deg.C, stirring, and keeping the temperature for 60 min;
(2) adding other raw materials of the phase B after the phase B carbomer and the water are fully dispersed and hydrated, heating to 70 ℃, uniformly stirring, and keeping the temperature for 15 minutes for later use;
(3) homogenizing phase B at 2000rmp for 10min by adding phase A into phase B; stirring at 20rpm, cooling to 50 deg.C, adding pH regulator in phase C, and stirring;
(4) stirring at 20rpm, cooling to below 37 deg.C, adding salmon proteoglycan, Bacillus prodigiosus nuclease, flos Lonicerae distillate and polyglutamic acid, and stirring at 20 rpm.
EXAMPLE five
The same technical features in this embodiment as those in the above embodiments are not described in detail, and the technical features of this embodiment different from those in the above embodiments are as follows:
the embodiment illustrates a salmon proteoglycan moisturizing skin care emulsion which is prepared from the following raw materials in percentage by mass: 10% of liquid paraffin, 8% of caprylic triglyceride and 10% of coconut oil; phase B: carbomer 0.2%, polyglutamic acid 1%, butanediol 15%, glycerol 15%, and xanthan gum 5%; and C phase: salmon proteoglycan-2%, bacillus prodigiosus nuclease 0.03%, honeysuckle flower distillate 20%, surfactant 5% and pH regulator 5%; the balance being deionized water.
The preparation method of the salmon proteoglycan moisturizing and skin-care emulsion in the embodiment comprises the following specific steps:
(1) heating phase A to 75 deg.C, stirring, and keeping the temperature for 45 min;
(2) adding other raw materials of the phase B after the phase B carbomer and the water are fully dispersed and hydrated, heating to 75 ℃, uniformly stirring, and preserving heat for 30 minutes for later use;
(3) homogenizing B phase at 3500rmp, adding A phase into B phase, and homogenizing for 5 min; stirring at 40rpm, cooling to 45 deg.C, adding pH regulator in phase C, and stirring;
(4) stirring at 30rpm, cooling to below 37 deg.C, adding salmon proteoglycan, Bacillus prodigiosus nuclease, flos Lonicerae distillate and polyglutamic acid, and stirring at 40 rpm.
The materials adopted by the invention, such as salmon proteoglycan, bacillus prodigiosus nuclease, honeysuckle flower distillate, polyglutamic acid and the like, are all in cosmetic grade, can be purchased from the market, and can also be prepared according to the prior art.
The salmon proteoglycan moisturizing and skin-protecting emulsion beauty fluid produced by the invention is rich in main functional components such as salmon proteoglycan, bacillus prodigiosus nuclease, honeysuckle dew, polyglutamic acid and the like through detection, has no stimulation and side effect on skin compared with the existing emulsion, can effectively improve skin metabolism, is beneficial to skin moisturizing and whitening, improves skin elasticity, removes wrinkles and the like.
Examples of the experiments
The effect of using the second emulsion of example was evaluated for one month and three months, respectively. The evaluation method comprises the following steps: the emulsions were applied to the dark yellow face, stain, acne and pockmark problems by volunteers and the effect of the application was determined according to table 1. Of these, 100 volunteers had dark yellow and pigmented spots, and 100 volunteers had acne and pockmarks on their faces.
The evaluation results are shown in tables 2 to 3.
Table 1 evaluation criteria: the number of persons considered to have an improvement effect was counted and evaluated based on the number of persons.
| Effect | Standard of merit |
| Has no effect | At most 50 out of 100 volunteers thought the skin problems associated with the treatment were resolved |
| Slightly effective fruit | Out of 100 volunteers, 51-80 considered the related skin problems to be solved |
| Remarkable effect | Of the 100 volunteers, up to 81 considered the related skin problems to be solved |
Table 2 the number of people using effective improvement was counted for facial problems.
Table 3 addresses the face problem evaluation results.
As can be seen from tables 2 to 3 and fig. 1, the salmon proteoglycan moisturizing skin care emulsion of the above embodiments of the present invention not only does not cause skin allergy, but also can significantly improve skin problems, and has significant whitening and moisturizing effects.
The above description is only a preferred embodiment of the application and is illustrative of the principles of the technology employed. It will be appreciated by a person skilled in the art that the scope of the invention as referred to in the present application is not limited to the embodiments with a specific combination of the above-mentioned features, but also covers other embodiments with any combination of the above-mentioned features or their equivalents without departing from the inventive concept. For example, the above features may be replaced with (but not limited to) features having similar functions disclosed in the present application.
Other technical features than those described in the specification are known to those skilled in the art, and are not described herein in detail in order to highlight the innovative features of the present invention.
Claims (6)
1. The salmon proteoglycan moisturizing skin-care emulsion is characterized by comprising the following components in parts by weight: the composition is prepared from the following raw materials in percentage by mass: 5-10% of liquid paraffin, 5-10% of caprylic triglyceride and 5-10% of coconut oil; phase B: 0.1-0.2% of carbomer, 0.05-2% of polyglutamic acid, 5-15% of butanediol, 5-15% of glycerol and 1-5% of xanthan gum; and C phase: salmon proteoglycan 0.5-2%, bacillus prodigiosus nuclease 0.01-0.05%, honeysuckle flower distillate 5-20%, surfactant 1-5%, and pH regulator 0.01-5%; the balance being deionized water.
2. The salmon proteoglycan moisturizing skin care emulsion of claim 1, characterized by: the composition is prepared from the following raw materials in percentage by mass: 7-9% of liquid paraffin, 6-8% of caprylic triglyceride and 6-8% of coconut oil; phase B: 0.1-0.2% of carbomer, 1-1.5% of polyglutamic acid, 8-10% of butanediol, 8-10% of glycerol and 2-3% of xanthan gum; and C phase: 1-1.5% of salmon proteoglycan, 0.01-0.03% of bacillus prodigiosus nuclease, 8-15% of honeysuckle flower distillate, 1-3% of surfactant and 2-3% of pH regulator; the balance being deionized water.
3. The salmon proteoglycan moisturizing skin care emulsion of claim 1, characterized by: the salmon proteoglycan moisturizing skin-care emulsion is prepared from the following raw materials in percentage by mass: 8% of liquid paraffin, 7% of caprylic triglyceride and 9% of coconut oil; phase B: 0.15% of carbomer, 1% of polyglutamic acid, 10% of butanediol, 10% of glycerol and 3% of xanthan gum; and C phase: 1% of salmon proteoglycan, 0.02% of bacillus prodigiosus nuclease, 15% of honeysuckle flower distillate, 3% of surfactant and 3% of pH regulator; the balance being deionized water.
4. Use of the moisturizing and skin-care emulsion of claims 1-3 for preparing a skin moisturizing and whitening cosmetic.
5. Use of the moisturizing skin care emulsion of claims 1-3 for the preparation of a cosmetic for increasing the elasticity of the skin.
6. Use of the moisturizing skin care emulsion of claims 1-3 for preparing a wrinkle-removing cosmetic.
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