CN110195069A - 共有抗原构建体和由其制备的疫苗以及使用所述疫苗治疗疟疾的方法 - Google Patents
共有抗原构建体和由其制备的疫苗以及使用所述疫苗治疗疟疾的方法 Download PDFInfo
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Classifications
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
- A61K39/015—Hemosporidia antigens, e.g. Plasmodium antigens
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/195—Chemokines, e.g. RANTES
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
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- A—HUMAN NECESSITIES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/208—IL-12
-
- A—HUMAN NECESSITIES
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2086—IL-13 to IL-16
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- A—HUMAN NECESSITIES
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- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
-
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
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- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Body Structure For Vehicles (AREA)
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| CN2011800513670A CN103354750A (zh) | 2010-09-27 | 2011-09-27 | 共有抗原构建体和由其制备的疫苗以及使用所述疫苗治疗疟疾的方法 |
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| CN2011800513670A Division CN103354750A (zh) | 2010-09-27 | 2011-09-27 | 共有抗原构建体和由其制备的疫苗以及使用所述疫苗治疗疟疾的方法 |
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| CN110195069A true CN110195069A (zh) | 2019-09-03 |
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| CN201910279715.8A Pending CN110195069A (zh) | 2010-09-27 | 2011-09-27 | 共有抗原构建体和由其制备的疫苗以及使用所述疫苗治疗疟疾的方法 |
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| CN2011800513670A Pending CN103354750A (zh) | 2010-09-27 | 2011-09-27 | 共有抗原构建体和由其制备的疫苗以及使用所述疫苗治疗疟疾的方法 |
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| Country | Link |
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| EP (1) | EP2621540A4 (enExample) |
| JP (1) | JP6293485B2 (enExample) |
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| EP2796147A1 (en) * | 2013-04-24 | 2014-10-29 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Novel vaccines against apicomplexan pathoges |
| EP2923709A1 (en) * | 2014-03-28 | 2015-09-30 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Multi-component-multistage malaria vaccine |
| EP2992895A1 (en) * | 2014-09-08 | 2016-03-09 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Three-component-multistage malaria vaccine |
| CN105628928A (zh) * | 2014-11-11 | 2016-06-01 | 深圳国际旅行卫生保健中心 | 可用于辅助诊断疟疾的试剂盒 |
| EP3247390A4 (en) * | 2015-01-23 | 2018-03-07 | The Trustees Of The University Of Pennsylvania | Immunogenicity of an optimized synthetic consensus dna vaccine for porcine epidemic diarrhea virus |
| EP3081575A1 (en) * | 2015-04-12 | 2016-10-19 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Anti-plasmodium parasite antibodies |
| US12398184B2 (en) | 2016-11-01 | 2025-08-26 | Washington University | Compositions comprising CelTOS immunogens and antibodies and method of use thereof |
| WO2018156106A1 (en) * | 2017-02-22 | 2018-08-30 | Ding Enyu | An mrna cancer vaccine encoding human gm-csf fused to multiple tandem epitopes |
| CN109125740B (zh) * | 2017-06-28 | 2022-04-05 | 成都威斯克生物医药有限公司 | 一种新型的肿瘤疫苗及其用途 |
| KR102169664B1 (ko) * | 2019-02-26 | 2020-10-23 | 원광대학교산학협력단 | 열대열말라리아원충 유래의 EF-1α 재조합 단백질을 유효성분으로 포함하는 말라리아 예방용 백신 조성물 |
| WO2022204597A1 (en) * | 2021-03-26 | 2022-09-29 | David Weiner | Dna encoded nanoparticle vaccine against human papillomavirus, and methods of use thereof |
| WO2025024337A1 (en) * | 2023-07-24 | 2025-01-30 | BioNTech SE | Compositions for delivery of plasmodium antigens and related methods |
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| US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
| IL105914A0 (en) | 1992-06-04 | 1993-10-20 | Univ California | Methods and compositions for in vivo gene therapy |
| US5273525A (en) | 1992-08-13 | 1993-12-28 | Btx Inc. | Injection and electroporation apparatus for drug and gene delivery |
| DE69434469T2 (de) | 1993-01-26 | 2006-06-14 | Univ Pennsylvania | Zusammensetzungen und verfahren zur verabreichung von genetischem material |
| CA2285056C (en) | 1997-04-03 | 2004-12-14 | Iacob Mathiesen | Method for introducing pharmaceutical drugs and nucleic acids into skeletal muscle |
| US6261281B1 (en) | 1997-04-03 | 2001-07-17 | Electrofect As | Method for genetic immunization and introduction of molecules into skeletal muscle and immune cells |
| JP2002507985A (ja) | 1997-06-30 | 2002-03-12 | ローヌ−プーラン・ロレ・エス・アー | 横紋筋に核酸を導入する改良法およびその組合せ |
| US6697669B2 (en) | 1998-07-13 | 2004-02-24 | Genetronics, Inc. | Skin and muscle-targeted gene therapy by pulsed electrical field |
| US8209006B2 (en) | 2002-03-07 | 2012-06-26 | Vgx Pharmaceuticals, Inc. | Constant current electroporation device and methods of use |
| US7245963B2 (en) | 2002-03-07 | 2007-07-17 | Advisys, Inc. | Electrode assembly for constant-current electroporation and use |
| US7328064B2 (en) | 2002-07-04 | 2008-02-05 | Inovio As | Electroporation device and injection apparatus |
| AU2003298361B2 (en) | 2002-12-17 | 2009-05-14 | Crucell Holland B.V. | Recombinant viral-based malaria vaccines |
| TWI303275B (en) | 2003-05-30 | 2008-11-21 | Advisys Inc | Devices and methods for biomaterial production |
| US7981601B2 (en) | 2003-08-01 | 2011-07-19 | Institute Of Basic Medical Sciences | Method of preparing polyepitope chimeric gene vaccine |
| US8168166B2 (en) * | 2003-12-19 | 2012-05-01 | Seattle Biomedical Research Institute | Live genetically attenuated malaria vaccine |
| CA2620495A1 (en) * | 2005-08-31 | 2007-03-08 | Genvec, Inc. | Adenoviral vector-based malaria vaccines |
| JP5508266B2 (ja) * | 2007-08-13 | 2014-05-28 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | ワクチン |
| CN105535961A (zh) | 2008-04-04 | 2016-05-04 | 宾夕法尼亚大学托管会 | 使用il-28和组合物的疫苗和免疫治疗及其使用方法 |
| WO2010062859A2 (en) * | 2008-11-25 | 2010-06-03 | United States Department Of The Army, As Respresented By The Secretary Of The Army | Recombinantly expressed plasmodium celtos antigen and methods of use thereof |
| US20110229514A1 (en) * | 2009-03-16 | 2011-09-22 | Denise Doolan | Vaccine and immunization method using plasmodium antigen 2 |
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2011
- 2011-09-27 WO PCT/US2011/053541 patent/WO2012047679A2/en not_active Ceased
- 2011-09-27 KR KR1020137010740A patent/KR101891195B1/ko not_active Expired - Fee Related
- 2011-09-27 US US13/876,148 patent/US10799572B2/en active Active
- 2011-09-27 CN CN2011800513670A patent/CN103354750A/zh active Pending
- 2011-09-27 CN CN201910279715.8A patent/CN110195069A/zh active Pending
- 2011-09-27 JP JP2013530426A patent/JP6293485B2/ja not_active Expired - Fee Related
- 2011-09-27 EP EP11831320.4A patent/EP2621540A4/en not_active Withdrawn
- 2011-09-27 MX MX2013003470A patent/MX355501B/es active IP Right Grant
- 2011-09-27 AU AU2011312465A patent/AU2011312465B2/en not_active Ceased
- 2011-09-27 CA CA2812789A patent/CA2812789A1/en not_active Abandoned
- 2011-09-27 KR KR1020187023719A patent/KR20180096814A/ko not_active Abandoned
- 2011-09-27 BR BR112013007051A patent/BR112013007051A2/pt not_active Application Discontinuation
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| ALYSSA E. BARRY等: "Contrasting Population Structures of the Genes Encoding Ten Leading Vaccine-Candidate Antigens of the Human Malaria Parasite，Plasmodium falciparum", 《POLSONE》 * |
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| P.GIRARD 等: "A review of human vaccine research and development:Malaria", 《VACCINE》 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012047679A8 (en) | 2012-08-16 |
| AU2011312465A1 (en) | 2013-05-02 |
| JP2013543721A (ja) | 2013-12-09 |
| US10799572B2 (en) | 2020-10-13 |
| WO2012047679A2 (en) | 2012-04-12 |
| KR20180096814A (ko) | 2018-08-29 |
| MX355501B (es) | 2018-04-20 |
| EP2621540A2 (en) | 2013-08-07 |
| US20130273112A1 (en) | 2013-10-17 |
| KR20130138790A (ko) | 2013-12-19 |
| KR101891195B1 (ko) | 2018-08-24 |
| AU2011312465B2 (en) | 2015-07-23 |
| CA2812789A1 (en) | 2012-04-12 |
| MX2013003470A (es) | 2013-08-01 |
| EP2621540A4 (en) | 2014-08-27 |
| BR112013007051A2 (pt) | 2019-07-02 |
| CN103354750A (zh) | 2013-10-16 |
| WO2012047679A3 (en) | 2012-06-14 |
| JP6293485B2 (ja) | 2018-03-14 |
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