CN110192110B - 无凝固蛋白原的澄清的鲎阿米巴样细胞裂解物 - Google Patents

无凝固蛋白原的澄清的鲎阿米巴样细胞裂解物 Download PDF

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CN110192110B
CN110192110B CN201880006683.8A CN201880006683A CN110192110B CN 110192110 B CN110192110 B CN 110192110B CN 201880006683 A CN201880006683 A CN 201880006683A CN 110192110 B CN110192110 B CN 110192110B
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lal
coagulogen
centrifuging
composition
clarified
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CN110192110A (zh
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C·斯特姆博
L·塔德塞
K·林
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Lonza Walkersville Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/579—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/50—Lipopolysaccharides; LPS
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
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  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN201880006683.8A 2017-01-11 2018-01-11 无凝固蛋白原的澄清的鲎阿米巴样细胞裂解物 Active CN110192110B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762445136P 2017-01-11 2017-01-11
US62/445,136 2017-01-11
PCT/US2018/013310 WO2018132562A1 (en) 2017-01-11 2018-01-11 Coagulogen-free clarified limulus amebocyte lysate

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CN110192110A CN110192110A (zh) 2019-08-30
CN110192110B true CN110192110B (zh) 2023-01-10

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US (2) US11352656B2 (https=)
EP (1) EP3552021B1 (https=)
JP (2) JP7507560B2 (https=)
KR (1) KR102545029B1 (https=)
CN (1) CN110192110B (https=)
IL (1) IL267593B2 (https=)
WO (1) WO2018132562A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7044222B2 (ja) 2016-08-03 2022-03-30 ロンザ ウォーカーズヴィル，インコーポレーテッド 実質的にコアギュローゲンを含まないリムルスアメボサイトライセートを使用してエンドトキシンを検出する方法
JP7507560B2 (ja) 2017-01-11 2024-06-28 ロンザ ウォーカーズヴィル，インコーポレーテッド コアギュローゲンを含まない、清澄化リムルスアメボサイトライセート
EP4709877A2 (en) * 2023-05-12 2026-03-18 Life Technologies Corporation Methods and kits for detecting endotoxin

Family Cites Families (18)

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KR0141685B1 (ko) * 1988-09-01 1998-07-01 야마따니 와따루 참게 아메보사이트 라이세이트 g 인자 활성화 저해제
ATE148230T1 (de) * 1989-10-30 1997-02-15 Biowhittaker Inc Kinetische bestimmungsmethode für endotoxin unter verwendung von limulus-amoebocyten-lysat und chromogenem substrat
JP3122454B2 (ja) * 1990-09-27 2001-01-09 生化学工業株式会社 カブトガニ・アメボサイト・ライセートの調製法
US5208148A (en) 1990-12-07 1993-05-04 Molecular Probes, Inc. Lipophilic fluorescent glycosidase substrates
US5242805A (en) 1991-08-23 1993-09-07 Molecular Probes, Inc. Long wavelength lipophilic fluorogenic glycosidase substrates
WO1993004192A1 (en) 1991-08-23 1993-03-04 Molecular Probes, Inc. Use of haloalkyl derivatives of reporter molecules to analyze metabolic activity in cells
US5576424A (en) 1991-08-23 1996-11-19 Molecular Probes, Inc. Haloalkyl derivatives of reporter molecules used to analyze metabolic activity in cells
JP3242733B2 (ja) * 1993-02-26 2001-12-25 生化学工業株式会社 エンドトキシン特異的測定剤
US5830912A (en) 1996-11-15 1998-11-03 Molecular Probes, Inc. Derivatives of 6,8-difluoro-7-hydroxycoumarin
US5773236A (en) 1997-04-25 1998-06-30 Molecule Probes, Inc. Assay for glutathiane transferase using polyhaloaryl-substituted reporter molecules
JP2010522540A (ja) * 2007-03-21 2010-07-08 アイディー バイオメディカル コーポレイション オブ ケベック キメラ抗原
WO2009063840A1 (ja) 2007-11-12 2009-05-22 Hiroshima University エンドトキシンの濃度測定方法および濃度測定用キット
US7846678B2 (en) 2008-08-18 2010-12-07 BioDtech, Inc. Enhancing endotoxin detection
MY155541A (en) * 2010-10-29 2015-10-30 Universiti Malaysia Terengganu Process for the preparation of amoebocyte lysate from the haemolymph of the horseshoe crab
CN102305788A (zh) * 2010-11-22 2012-01-04 天津市一瑞生物工程有限公司 革兰阴性菌脂多糖(内毒素)比色检测试剂盒的制备及其使用方法
JP7044222B2 (ja) * 2016-08-03 2022-03-30 ロンザ ウォーカーズヴィル，インコーポレーテッド 実質的にコアギュローゲンを含まないリムルスアメボサイトライセートを使用してエンドトキシンを検出する方法
JP7507560B2 (ja) 2017-01-11 2024-06-28 ロンザ ウォーカーズヴィル，インコーポレーテッド コアギュローゲンを含まない、清澄化リムルスアメボサイトライセート
SG11201912888TA (en) 2017-06-28 2020-01-30 Lonza Walkersville Inc Cartridge for endotoxin detection

Also Published As

Publication number Publication date
JP2023002669A (ja) 2023-01-10
KR20190104387A (ko) 2019-09-09
IL267593B1 (en) 2024-12-01
EP3552021B1 (en) 2022-10-26
JP7724762B2 (ja) 2025-08-18
JP2020505007A (ja) 2020-02-20
US20220267824A1 (en) 2022-08-25
IL267593B2 (en) 2025-04-01
US11352656B2 (en) 2022-06-07
CN110192110A (zh) 2019-08-30
WO2018132562A1 (en) 2018-07-19
KR102545029B1 (ko) 2023-06-19
IL267593A (en) 2019-08-29
JP7507560B2 (ja) 2024-06-28
US20180208964A1 (en) 2018-07-26
US12359241B2 (en) 2025-07-15
EP3552021A1 (en) 2019-10-16

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