CN110179695A - A kind of improvement memory compound essential oil and preparation method thereof - Google Patents

A kind of improvement memory compound essential oil and preparation method thereof Download PDF

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Publication number
CN110179695A
CN110179695A CN201910567096.2A CN201910567096A CN110179695A CN 110179695 A CN110179695 A CN 110179695A CN 201910567096 A CN201910567096 A CN 201910567096A CN 110179695 A CN110179695 A CN 110179695A
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CN
China
Prior art keywords
essential oil
oil
lavender
turmeric
rhizoma chuanxiong
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910567096.2A
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Chinese (zh)
Inventor
许敏
曹海龙
罗道玉
郑三会
李云辉
顾培爽
宋晖
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dongguan Huaipu Vegetable Essential Oil Co Ltd
Original Assignee
Dongguan Huaipu Vegetable Essential Oil Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dongguan Huaipu Vegetable Essential Oil Co Ltd filed Critical Dongguan Huaipu Vegetable Essential Oil Co Ltd
Priority to CN201910567096.2A priority Critical patent/CN110179695A/en
Publication of CN110179695A publication Critical patent/CN110179695A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/78Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782Enzyme inhibitors; Enzyme antagonists

Abstract

The invention discloses a kind of improvement memory compound essential oils and preparation method thereof, and compound essential oil includes the black pepper essential oil of 20-25wt%, the turmeric essential oil of 10-15wt%, the Rhizoma Chuanxiong essential oil of 20-25wt%, the Lavender of 5-10wt%, the Aplotaxis auriculata essential oil of 1-3wt% and the base oil of 44-22wt%;Essential oil provided by the invention is organic natural essential oil of extraction, prescription proportion science, safe without toxic side effect without any artificial synthesis group point.The effect of with inhibiting acetylcholine esterase activity and other effects, can effectively improve memory.

Description

A kind of improvement memory compound essential oil and preparation method thereof
Technical field
The present invention relates to cosmetic technical fields, and in particular to a kind of improvement memory and concentration compound essential oil and its preparation Method.
Background technique
Memory is that human brain crosses the memorize of things to experience, holding, reproduces or re-recognize, it is that progress thinking, imagination etc. are advanced The basis of psychological activity.Human mind is related with the chemical composition change inside cerebral hippocampus structure, brain.Hypomnesia is one Kind memory disorders, are mainly shown as the decline of remote memory and nearly memory.It is mainly seen in brain organic psychosis.Brain device matter Property damage patient occur that the decline of nearly memory earliest, patient does not remember the meal situation on these last few days or even the same day, or Do not remember within the next few days who once come to visit etc..Remote memory also declines after being in a bad way.For example, the nerveous systems such as senile dementia System retrogression pathological changes cause to remember serious hindrance.
Essential oil is a kind of natural skin-care nutrient liquid.It is that extraction is refined in the flower from plant, leaf, stem, root or fruit Volatile flavor causes the change of allergy with without essence, without chemical pigment, without preservative, without mineral grease, nothing Study point, adverse chemical ingredient the features such as.And the main chemical compositions molecular weight in essential oil is in 200-300 or so, it is active Now, the features such as being easy to through blood-brain barrier.
Summary of the invention
In view of the above-mentioned deficiencies in the prior art, it is an object of the present invention to provide a kind of improvement memory compound essential oil and its preparation side Method.Essential oil provided by the invention selects the plant extract containing active skull cap components to form, and prescription proportion science is not added any Artificial synthesized component, safe without toxic side effect, and have and significantly inhibit acetylcholine esterase activity, a variety of causes can be effectively relieved The symptoms such as caused memory disorders.In addition, essential oil provided by the invention is highly-safe, stability is good, easy to use, have extensive Application value.
The purpose of the present invention is achieved through the following technical solutions: a kind of improvement memory compound essential oil, comprising: 20- The lavender essence of the black pepper essential oil of 25wt%, the turmeric essential oil of 10-15wt%, the Rhizoma Chuanxiong essential oil of 20-25wt%, 5-10wt% Oil, the Aplotaxis auriculata essential oil of 1-3wt% and the base oil of 22-44wt%.
Further, comprising: the black pepper essential oil of 20wt%, the turmeric essential oil of 10wt%, 20wt% Rhizoma Chuanxiong essential oil, Lavender, the Aplotaxis auriculata essential oil of 1wt% and the base oil of 44wt% of 5wt%.
Further, the base oil is rose hip oil.
A kind of preparation method of above-mentioned compound essential oil, comprising the following steps:
(1) black pepper, turmeric, Rhizoma Chuanxiong, lavender, Aplotaxis auriculata are crushed respectively and is mentioned using steam distillation It takes, obtains black pepper essential oil, turmeric essential oil, Rhizoma Chuanxiong essential oil, Lavender, Aplotaxis auriculata essential oil;The steam distillation Extracting temperature is 100 DEG C -120 DEG C, extraction time 5h-7h.
(2) fructus rosae crushing is placed in squeezer and is squeezed, crude oil is collected by filtration, crude oil is placed in molecular distillation instrument Middle purification, obtains base oil.The feeding temperature of the molecularly distilled be 40 DEG C -45 DEG C, sample introduction speed be 480-530mL/h, one Section evaporating temperature is 110 DEG C -115 DEG C, and dual circulation temperature is 60 DEG C -65 DEG C, collects two sections of distillation fractions.
(3) the black pepper essential oil that obtains step 1, turmeric essential oil, Rhizoma Chuanxiong essential oil, Lavender, Aplotaxis auriculata essential oil and The base oil mixing that step 2 obtains, obtains compound essential oil;In compound essential oil, the quality proportioning of each component are as follows: 20-25wt%'s Black pepper essential oil, the turmeric essential oil of 10-15wt%, the Rhizoma Chuanxiong essential oil of 20-25wt%, the Lavender of 5-10wt%, 1- The Aplotaxis auriculata essential oil of 3wt% and the base oil of 22-44wt%.
The beneficial effects of the present invention are: the present invention provides a kind of preparation method of compound essential oil, this method process stabilizing, Yield is high, quality is good, low energy consumption.Essential oil provided by the invention selects the plants essential oil extract composition containing active skull cap components It forms, prescription proportion science does not add any artificial synthesis group point.Through human body and animal Efficacy experiments, toxicological test and metabolism Experimental study shows the essential oil being prepared using method provided by the invention, and safe without toxic side effect absorbs fastly, and has The effect of significantly inhibiting acetylcholine esterase isoreactivity, effectively improving memory.Essential oil provided by the invention is easy to use, directly Aroma diffusing in fumigating machine is applied to around nasal cavity or is placed in use.
Specific embodiment
The embodiment of technical solution of the present invention will be described in detail below.Following embodiment is only used for clearer Illustrate technical solution of the present invention, therefore be only used as example, and not intended to limit the protection scope of the present invention.
The present invention provides a kind of preparation method of compound essential oil, and raw material components include black pepper essential oil by weight 20-25 parts by weight, turmeric essential oil 10-15 parts by weight, Rhizoma Chuanxiong essential oil 20-25 parts by weight, Lavender 5-10 parts by weight, Yun Mu Essential oil 1-3 parts by weight and base oil 44-22 parts by weight.
Compound essential oil of the invention can also be formulated by raw material components by directly buying above-mentioned plants essential oil, Method can be prepared as follows to obtain: black pepper, turmeric, Rhizoma Chuanxiong, lavender, Aplotaxis auriculata are crushed respectively and steamed using vapor The method of evaporating extracts, and obtains black pepper essential oil, turmeric essential oil, Rhizoma Chuanxiong essential oil, Lavender, Aplotaxis auriculata essential oil;The water steams The Extracting temperature of steam distillation method is 100 DEG C -120 DEG C, extraction time 5h-7h;Fructus rosae is crushed to coarse granule and is placed on pressure It is squeezed in crusher, crude oil is collected by filtration, crude oil is placed in molecular distillation instrument and refines, and obtains base oil.The molecularly distilled Feeding temperature is 40 DEG C -45 DEG C, and sample introduction speed is 480-530mL/h, and one section of evaporating temperature is 110 DEG C -115 DEG C, dual circulation Temperature is 60 DEG C -65 DEG C, collects two sections of distillation fractions;By black pepper essential oil that step 1 obtains, turmeric essential oil, Rhizoma Chuanxiong essential oil, smoke The base oil mixing that clothing grass essential oil, Aplotaxis auriculata essential oil and step 2 obtain, obtains compound essential oil;In compound essential oil, the matter of each component Amount proportion are as follows: the black pepper essential oil of 20-25wt%, the turmeric essential oil of 10-15wt%, 20-25wt% Rhizoma Chuanxiong essential oil, 5- Lavender, the Aplotaxis auriculata essential oil of 1-3wt% and the base oil of 22-44wt% of 10wt%.
It is illustrated With reference to embodiment:
Embodiment 1:
Take 20 parts by weight of black pepper essential oil, 10 parts by weight of turmeric essential oil, 20 parts by weight of Rhizoma Chuanxiong essential oil, 5 weight of Lavender It measures part, 44 parts by weight of 1 parts by weight of Aplotaxis auriculata essential oil and rose hip oil, is uniformly mixed to obtain the final product.
Embodiment 2:
Take 25 parts by weight of black pepper essential oil, 15 parts by weight of turmeric essential oil, 25 parts by weight of Rhizoma Chuanxiong essential oil, 10 weight of Lavender It measures part, 22 parts by weight of 3 parts by weight of Aplotaxis auriculata essential oil and rose hip oil, is uniformly mixed to obtain the final product.
Embodiment 3:
After black pepper, turmeric, Rhizoma Chuanxiong, lavender, Aplotaxis auriculata are crushed respectively, extracted using steam distillation, 110 DEG C of evaporating temperature, distillation time 5h obtains plants essential oil;Fructus rosae is crushed to coarse granule to be placed in squeezer Squeezing, crude oil is collected by filtration, crude oil is placed in molecular distillation instrument, feeding temperature be 45 DEG C, sample introduction speed be 530mL/h, one Section evaporating temperature is 115 DEG C, and dual circulation temperature is 65 DEG C, collects two sections of distillation fractions, obtains base oil;By above-mentioned essential oil and base Plinth oil is smart by the lavender of the black pepper essential oil of 25wt%, the turmeric essential oil of 15wt%, the Rhizoma Chuanxiong essential oil of 25wt%, 10wt% The proportion of the base oil of oil, the Aplotaxis auriculata essential oil of 3wt% and 22wt% is uniformly mixed, and obtains compound essential oil.
Embodiment 4:
Improve memory experiment:
It extracts 100 triers and tries out being sprayed for the present embodiment 1.By before training, after training and resurvey and test preceding 3 kinds of differences Give tested crowd by fumigating machine aroma diffusing, observe it to memory overall process (acquisition of memory, memory consolidation, memory reproduce) Influence.80% trier's memory improves, and 10% trier does not significantly improve, and 10% trier does not improve.
Above-described embodiment is used to illustrate the present invention, rather than limits the invention, in spirit of the invention and In scope of protection of the claims, to any modifications and changes that the present invention makes, protection scope of the present invention is both fallen within.

Claims (4)

1. compound essential oil is remembered in a kind of improvement characterized by comprising the black pepper essential oil of 20-25wt%, 10-15wt% Turmeric essential oil, the Rhizoma Chuanxiong essential oil of 20-25wt%, the Lavender of 5-10wt%, 1-3wt% Aplotaxis auriculata essential oil and 22- The base oil of 44wt%.
2. improving memory compound essential oil according to claim 1 characterized by comprising the black pepper essential oil of 20wt%, The turmeric essential oil of 10wt%, the Rhizoma Chuanxiong essential oil of 20wt%, the Lavender of 5wt%, 1wt% Aplotaxis auriculata essential oil and 44wt% Base oil.
3. improving memory compound essential oil according to claim 1, which is characterized in that the base oil is rose hip oil.
4. a kind of preparation method of compound essential oil described in claim 1, which comprises the following steps:
(1) black pepper, turmeric, Rhizoma Chuanxiong, lavender, Aplotaxis auriculata are crushed respectively and is extracted using steam distillation, obtained To black pepper essential oil, turmeric essential oil, Rhizoma Chuanxiong essential oil, Lavender, Aplotaxis auriculata essential oil;The extraction temperature of the steam distillation Degree is 100 DEG C -120 DEG C, extraction time 5h-7h.
(2) fructus rosae crushing is placed in squeezer and is squeezed, crude oil is collected by filtration, crude oil is placed in molecular distillation instrument smart System, obtains base oil.The feeding temperature of the molecularly distilled is 40 DEG C -45 DEG C, and sample introduction speed is 480-530mL/h, one section of steaming Sending out temperature is 110 DEG C -115 DEG C, and dual circulation temperature is 60 DEG C -65 DEG C, collects two sections of distillation fractions.
(3) black pepper essential oil, turmeric essential oil, Rhizoma Chuanxiong essential oil, Lavender, Aplotaxis auriculata essential oil and the step 2 obtained step 1 Obtained base oil mixing, obtains compound essential oil;In compound essential oil, the quality proportioning of each component are as follows: the black pepper of 20-25wt% Essential oil, the turmeric essential oil of 10-15wt%, the Rhizoma Chuanxiong essential oil of 20-25wt%, the Lavender of 5-10wt%, 1-3wt% cloud The base oil of radix aucklandiae essential oil and 22-44wt%.
CN201910567096.2A 2019-06-27 2019-06-27 A kind of improvement memory compound essential oil and preparation method thereof Pending CN110179695A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113684095A (en) * 2021-08-25 2021-11-23 传香(上海)生物科技有限公司 Compound essential oil, preparation method thereof and product for improving learning and memory ability

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103002902A (en) * 2010-05-19 2013-03-27 皮肤生命株式会社 Cosmetic composition containing a cypress essential oil complex as an active ingredient for enhancing memory and improving cognitive dysfunction
CN105853885A (en) * 2016-05-20 2016-08-17 福建万亿店中店电子商务有限责任公司 Compound essential oil containing rose hips
CN107095920A (en) * 2017-03-28 2017-08-29 湖南玖朵玫瑰香商贸有限公司 A kind of rose scent compound plant essential oil
CN107233412A (en) * 2017-05-27 2017-10-10 江西中医药大学 It is a kind of to promote compound essential oil composition of sleep and its production and use

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103002902A (en) * 2010-05-19 2013-03-27 皮肤生命株式会社 Cosmetic composition containing a cypress essential oil complex as an active ingredient for enhancing memory and improving cognitive dysfunction
CN105853885A (en) * 2016-05-20 2016-08-17 福建万亿店中店电子商务有限责任公司 Compound essential oil containing rose hips
CN107095920A (en) * 2017-03-28 2017-08-29 湖南玖朵玫瑰香商贸有限公司 A kind of rose scent compound plant essential oil
CN107233412A (en) * 2017-05-27 2017-10-10 江西中医药大学 It is a kind of to promote compound essential oil composition of sleep and its production and use

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113684095A (en) * 2021-08-25 2021-11-23 传香(上海)生物科技有限公司 Compound essential oil, preparation method thereof and product for improving learning and memory ability
CN113684095B (en) * 2021-08-25 2023-12-26 安丽丽 Compound essential oil, preparation method thereof and product for improving learning and memory capacity

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Application publication date: 20190830