CN110167957A - 用于治疗自身免疫疾病的il-2变体 - Google Patents
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Cited By (1)
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| WO2021093633A1 (zh) * | 2019-09-10 | 2021-05-20 | 中国医学科学院北京协和医院 | 靶向调节t细胞的长效白介素-2及其在治疗自身免疫病中的应用 |
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| US9959384B2 (en) | 2013-12-10 | 2018-05-01 | Bioniz, Llc | Methods of developing selective peptide antagonists |
| CN119684428A (zh) | 2015-10-09 | 2025-03-25 | 比奥尼斯治疗公司 | 调节γC-细胞因子活性 |
| US20170204154A1 (en) | 2016-01-20 | 2017-07-20 | Delinia, Inc. | Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases |
| BR112019018915A2 (pt) | 2017-03-15 | 2020-04-14 | Pandion Therapeutics Inc | imunotolerância direcionada |
| US11879014B2 (en) | 2017-03-17 | 2024-01-23 | Tusk Therapeutics Ltd. | Method of treating cancer or depleting regulatory T cells in a subject by administering a human IGG1 anti-CD25 antibody |
| WO2018187499A1 (en) | 2017-04-07 | 2018-10-11 | Bioniz, Llc | Stable modulators of gamma-c-cytokine activity |
| JP2020521452A (ja) | 2017-05-24 | 2020-07-27 | パンディオン・セラピューティクス・インコーポレイテッド | 標的化免疫寛容 |
| US20200299349A1 (en) | 2017-11-21 | 2020-09-24 | The Board Of Trustees Of The Leland Stanford Junior University | Partial agonists of interleukin-2 |
| US10174091B1 (en) | 2017-12-06 | 2019-01-08 | Pandion Therapeutics, Inc. | IL-2 muteins |
| USRE50550E1 (en) | 2017-12-06 | 2025-08-26 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| US10946068B2 (en) | 2017-12-06 | 2021-03-16 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| US11319355B2 (en) | 2017-12-19 | 2022-05-03 | Xencor, Inc. | Engineered IL-2 Fc fusion proteins |
| KR102909650B1 (ko) | 2018-03-13 | 2026-01-08 | 터스크 테라퓨틱스 리미티드 | 종양 특이적 세포 고갈에 대한 항-cd25 |
| JP7464530B2 (ja) | 2018-03-28 | 2024-04-09 | ブリストル－マイヤーズ スクイブ カンパニー | インターロイキン－２／インターロイキン－２受容体アルファ融合タンパク質および使用方法 |
| JP7637415B2 (ja) * | 2018-06-22 | 2025-02-28 | キュージーン インコーポレイテッド | インターロイキン－２バリアントおよびその使用方法 |
| WO2020007937A1 (en) * | 2018-07-03 | 2020-01-09 | Iltoo Pharma | Use of interleukin-2 for treating systemic sclerosis |
| MX2021001493A (es) | 2018-08-06 | 2021-07-15 | Medikine Inc | Compuestos de fijación al receptor de il-2. |
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| KR20220110207A (ko) | 2019-11-05 | 2022-08-05 | 메디카인 인코포레이티드 | IL-2RβγC 결합 화합물 |
| BR112022012112A2 (pt) | 2019-12-20 | 2022-09-06 | Regeneron Pharma | Agonistas de il2 e métodos de uso dos mesmos |
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| CN121319219A (zh) * | 2020-01-14 | 2026-01-13 | 辛德凯因股份有限公司 | Il2突变蛋白 |
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| JP2023512687A (ja) | 2020-02-03 | 2023-03-28 | メディカイン、インコーポレイテッド | ＩＬ－７Ｒα結合化合物 |
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- 2017-11-08 SG SG11201903882VA patent/SG11201903882VA/en unknown
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2022
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| WO2021093633A1 (zh) * | 2019-09-10 | 2021-05-20 | 中国医学科学院北京协和医院 | 靶向调节t细胞的长效白介素-2及其在治疗自身免疫病中的应用 |
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| JP2019532996A (ja) | 2019-11-14 |
| EA201991142A1 (ru) | 2019-10-31 |
| IL266178A (en) | 2019-06-30 |
| US20180125941A1 (en) | 2018-05-10 |
| CL2019001265A1 (es) | 2019-10-04 |
| CA3041334A1 (en) | 2018-05-17 |
| JP2022119829A (ja) | 2022-08-17 |
| ECSP19041447A (es) | 2019-07-31 |
| AU2017359172A1 (en) | 2019-05-16 |
| SG11201903882VA (en) | 2019-05-30 |
| US11077172B2 (en) | 2021-08-03 |
| KR20190083656A (ko) | 2019-07-12 |
| EP3538548A4 (en) | 2020-08-19 |
| MX2019005400A (es) | 2019-08-05 |
| EP3538548A1 (en) | 2019-09-18 |
| CO2019005922A2 (es) | 2019-08-30 |
| US20210308222A1 (en) | 2021-10-07 |
| WO2018089420A1 (en) | 2018-05-17 |
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