CN110151609A - A kind of anti-anxiety compound essential oil and preparation method thereof - Google Patents
A kind of anti-anxiety compound essential oil and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of anti-anxiety compound essential oil and preparation method thereof, compound essential oil includes: 20-25wt% Pogostemon cablin essential, 10-15wt% bergamot, 20-25wt% Lavender, 5-10wt% sandalwood essential oil, 1-3wt% cus-cus essential oil and 22-44wt% base oil.Essential oil provided by the invention is organic natural essential oil of extraction, prescription proportion science, safe without toxic side effect without any artificial synthesis group point.With antidepressant effect, the symptoms such as anxiety caused by depression, depressed, insomnia, headache can be effectively relieved.
Description
Technical field
The present invention relates to cosmetic technical fields, and in particular to a kind of anti-anxiety compound essential oil and preparation method thereof.
Background technique
Depression belongs to emotion obstacle class disease.WHO estimation, global depressive patient has hundred million people of 1.2-2, and predicts 2020
Year depression will become human death and the disabled second largest disease.Depression is mainly shown as that depressed, mental state is dejected, emerging
Interest lose, emotional affection is indifferent, fidgety, elaborative faculty decline, feels oneself inferior, feeling guilty, from it is liquor-saturated, commit suiside etc. ideas.Depression is suffered from throughout one's life
Sick rate is 6.1-9.5%, and the people of about 13-20% once had the depression experience of once or more.With illness rate height, disable
The features such as rate height and the high death rate.
Depression mechanism complex, Bunney etc. first proposed monoamine hypothesis mechanism.Nineteen sixty-five Coppen,
Shaw et al. discovery, maincenter, which lacks serotonin, can cause depression.Randrup is proposed first within 1975, and DA may participate in depression
One of the reason of morbidity of disease, dopaminergic is lowly also depression.Then, have also been proposed neurotrophic factor hypothesis,
The number of mechanisms such as hypothalamic-pituitary-adrenal (HAP) axis imbalance.But etiology unknown depressed so far, mechanism are unclear.It leads
The finiteness of current anti depressant medication effect is caused.In clinical practice, it is intended to by selecting a variety of methods to treat depression,
Wish to obtain better antidepressant effect.But there is the disadvantages of toxicity is big, drug effect is bad.
Essential oil is a kind of mixture of natural volatile small molecule, is in the flower from plant, leaf, stem, root or fruit
The volatile flavor of extraction is refined, it is active strong, it is easy the features such as passing through blood-brain barrier.Such as Lavender is in Europe
Continent has been used for the clinical medicine for treating anxiety disorder.
Summary of the invention
In view of the above-mentioned deficiencies in the prior art, it is an object of the present invention to provide a kind of anti-anxiety compound essential oil and its preparation side
Method.Essential oil provided by the invention selects the plant extract containing active skull cap components to form, prescription proportion science, and has significant
Antidepressant effect, can be effectively relieved depression induction it is depressed, mental state is dejected, hebetude, emotional affection are indifferent, sitting not
The symptoms such as peace, elaborative faculty decline, insomnia.In addition, essential oil provided by the invention is highly-safe, stability is good, easy to use, tool
Have a wide range of applications.
The purpose of the present invention is achieved through the following technical solutions: a kind of anti-anxiety compound essential oil, comprising: 20-
25wt% Pogostemon cablin essential, 10-15wt% Bergamot, 20-25wt% Lavender, 5-10wt% sandalwood essential oil, 1-
3wt% cus-cus essential oil and 22-44wt% base oil.
Further, comprising: 20wt% Pogostemon cablin essential, 10wt% bergamot, 20wt% Lavender, 5wt% wingceltis
Essential oil, 1wt% cus-cus essential oil and 44wt% base oil.
Further, the base oil is oenothera seed oil.
A kind of preparation method of above-mentioned compound essential oil, comprising the following steps:
(1) it after crushing santal, is extracted using supercritical carbon dioxide, reuses molecularly distilled and extract, obtain
Sandalwood essential oil；The temperature that the supercritical carbon dioxide extracts is 45 DEG C -48 DEG C, pressure 13.70MPa-17.80MPa, the time
For 50min-100min, the flow velocity of carbon dioxide is 25kg/h-35kg/h；The feeding temperature of the molecularly distilled be 40 DEG C-
45 DEG C, sample introduction speed is 480-530mL/h, and one section of evaporating temperature is 110 DEG C -115 DEG C, and dual circulation temperature is 60 DEG C -65 DEG C.
(2) it is extracted after crushing Pogostemon cablin, lavender, cus-cus respectively using steam distillation, obtains the wide leaves of pulse plants
Essential oil, Lavender, cus-cus essential oil；The steam distillation, vapo(u)rizing temperature are 100 DEG C -120 DEG C, distillation time
It is 5-7 hours.
(3) bergamot crushing is placed in squeezer and is squeezed, crude oil is collected by filtration, is refined using molecularly distilled,
Obtain Bergamot；The feeding temperature of the molecularly distilled is 40 DEG C -45 DEG C, and sample introduction speed is 480-530mL/h, one section of steaming
Sending out temperature is 110 DEG C -115 DEG C, and dual circulation temperature is 60 DEG C -65 DEG C.
(4) it after crushing oenothera seed, is extracted using supercritical carbon dioxide, reuses molecularly distilled and extract,
Obtain base oil；The temperature that the supercritical carbon dioxide extracts is 45 DEG C -48 DEG C, pressure 13.70MPa-17.80MPa, the time
For 50min-100min, the flow velocity of carbon dioxide is 25kg/h-35kg/h；The feeding temperature of the molecularly distilled be 40 DEG C-
45 DEG C, sample introduction speed is 480-530mL/h, and one section of evaporating temperature is 110 DEG C -115 DEG C, and dual circulation temperature is 60 DEG C -65 DEG C；
(5) sandalwood essential oil for obtaining step 1, Pogostemon cablin essential that step 2 obtains, Lavender, cus-cus essential oil,
The base oil that the Bergamot and step 4 that step 3 obtains obtain is uniformly mixed, and obtains compound essential oil；In compound essential oil, each group
The quality proportioning divided are as follows: 20-25wt% Pogostemon cablin essential, 10-15wt% Bergamot, 20-25wt% Lavender, 5-
10wt% sandalwood essential oil, 1-3wt% cus-cus essential oil and 22-44wt% base oil.
The beneficial effects of the present invention are: the present invention provides a kind of preparation method of compound essential oil, this method process stabilizing,
Yield is high, quality is good, low energy consumption.Essential oil provided by the invention selects the plants essential oil extract composition containing active skull cap components
It forms, prescription proportion science does not add any artificial synthesis group point.Through human body and animal Efficacy experiments, toxicological test and metabolism
Experimental study shows the essential oil being prepared using method provided by the invention, and safe without toxic side effect absorbs fastly, and has
Significant the effect of alleviating depressive symptom.Essential oil provided by the invention is easy to use, is directly applied to around nasal cavity or instills bath
Bathing in cylinder, or instill in fumigating machine and used by aroma diffusing.
Specific embodiment
The embodiment of technical solution of the present invention will be described in detail below.Following embodiment is only used for clearer
Illustrate technical solution of the present invention, therefore be only used as example, and not intended to limit the protection scope of the present invention.
The present invention provides a kind of preparation method of compound essential oil, and raw material components include Pogostemon cablin essential by weight
20-25 parts by weight, bergamot 10-15 parts by weight, Lavender 20-25 parts by weight, sandalwood essential oil 5-10 parts by weight, cus-cus
Essential oil 1-3 parts by weight and base oil 44-22 parts by weight.
Compound essential oil of the invention can also be formulated by raw material components by directly buying above-mentioned plants essential oil,
Method can be prepared as follows to obtain: after sandalwood essential oil is extracted using supercritical carbon dioxide, reusing molecularly distilled progress
It extracts；It is extracted after Pogostemon cablin, lavender are crushed respectively using steam distillation；Squeezing method mentions after bergamot is crushed
It takes, and is refined by molecularly distilled, obtain Bergamot；Oenothera seed is extracted after crushing using supercritical carbon dioxide, then
It is refined by molecularly distilled, obtains base oil；The extraction of essential oil object and the base oil are pressed into 20 weight of Pogostemon cablin essential
Measure part, 10 parts by weight of bergamot, 20 parts by weight of Lavender, 5 parts by weight of sandalwood essential oil, 1 parts by weight of cus-cus essential oil and base
Plinth 44 parts by weight of oil are uniformly mixed, and obtain compound essential oil.
It is illustrated With reference to embodiment:
Embodiment 1:
Take 20 parts by weight of Pogostemon cablin essential, 10 parts by weight of bergamot, 20 parts by weight of Lavender, 5 weight of sandalwood essential oil
Part, 44 parts by weight of 1 parts by weight of cus-cus essential oil and oenothera seed oil are uniformly mixed to obtain the final product.
Embodiment 2:
Take 25 parts by weight of Pogostemon cablin essential, 15 parts by weight of Bergamot, 25 parts by weight of Lavender, sandalwood essential oil 10
22 parts by weight of parts by weight, 3 parts by weight of cus-cus essential oil and oenothera seed oil are uniformly mixed to obtain the final product.
Embodiment 3:
Santal is taken to extract using supercritical carbon dioxide, temperature is 45 DEG C, pressure 13.70MPa, time 50min, stream
Speed is 25kg/h；By extract again into molecular distillation is crossed, feeding temperature is 40 DEG C, and sample introduction speed is 480mL/h, one section of evaporation temperature
Degree is 110 DEG C, and dual circulation temperature is 60 DEG C, obtains sandalwood essential oil；It is steamed after Pogostemon cablin, lavender are crushed respectively using vapor
The method of evaporating extracts, and 100 degree of vapo(u)rizing temperature, distillation time is 5 hours, obtains Pogostemon cablin essential and Lavender；By bergamot
Crushing is that coarse granule is placed in squeezer, and squeeze and filter obtains crude oil, and is refined by molecularly distilled, feeding temperature 40
DEG C, sample introduction speed is 480mL/h, and one section of evaporating temperature is 110 DEG C, and dual circulation temperature is 60 DEG C, obtains Bergamot；Take the moon
See that grass-seed is extracted using supercritical carbon dioxide, temperature is 45 DEG C, pressure 13.70MPa, time 50min, and flow velocity is
25kg/h；By extract again into molecular distillation is crossed, feeding temperature is 40 DEG C, and sample introduction speed is 480mL/h, and one section of evaporating temperature is
110 DEG C, dual circulation temperature is 60 DEG C, obtains base oil；Above-mentioned extraction of essential oil object and basic oil extract are pressed into Pogostemon cablin essential
20 parts by weight, 10 parts by weight of bergamot, 20 parts by weight of Lavender, 5 parts by weight of sandalwood essential oil, 1 parts by weight of cus-cus essential oil
It is uniformly mixed with 44 parts by weight of base oil, obtains compound essential oil.
Embodiment 4:
Antidepression experiment:
The recurrence essential oil in 100 triers the present embodiment 1 on probation is extracted, is used by fumigating machine aroma diffusing.Once a day,
3 hours every time, persistently using after 1 month, the improvement situation to depression is investigated by questionnaire form.60% trier's depression
Shape significantly improves, and 20% trier's depressive symptom has certain improvement, and 20% trier does not improve.
Above-described embodiment is used to illustrate the present invention, rather than limits the invention, in spirit of the invention and
In scope of protection of the claims, to any modifications and changes that the present invention makes, protection scope of the present invention is both fallen within.
Claims (4)
1. a kind of anti-anxiety compound essential oil characterized by comprising 20-25wt% Pogostemon cablin essential, 10-15wt% bergamot
Essential oil, 20-25wt% Lavender, 5-10wt% sandalwood essential oil, 1-3wt% cus-cus essential oil and 22-44wt% base oil.
2. anti-anxiety compound essential oil according to claim 1 characterized by comprising 20wt% Pogostemon cablin essential, 10wt%
Bergamot, 20wt% Lavender, 5wt% sandalwood essential oil, 1wt% cus-cus essential oil and 44wt% base oil.
3. anti-anxiety compound essential oil according to claim 1, which is characterized in that the base oil is oenothera seed oil.
4. a kind of preparation method of compound essential oil described in claim 1, which comprises the following steps:
(1) it after crushing santal, is extracted using supercritical carbon dioxide, reuses molecularly distilled and extract, obtain santal
Essential oil；The temperature that the supercritical carbon dioxide extracts is 45 DEG C -48 DEG C, pressure 13.70MPa-17.80MPa, and the time is
50min-100min, the flow velocity of carbon dioxide are 25kg/h-35kg/h；The feeding temperature of the molecularly distilled is 40 DEG C -45
DEG C, sample introduction speed is 480-530mL/h, and one section of evaporating temperature is 110 DEG C -115 DEG C, and dual circulation temperature is 60 DEG C -65 DEG C.
(2) it is extracted after crushing Pogostemon cablin, lavender, cus-cus respectively using steam distillation, obtains Pogostemon cablin essence
Oil, Lavender, cus-cus essential oil；The steam distillation, vapo(u)rizing temperature are 100 DEG C -120 DEG C, distillation time 5-7
Hour.
(3) bergamot crushing is placed in squeezer and is squeezed, crude oil is collected by filtration, is refined using molecularly distilled, obtains Buddhist
Hand mandarin orange essential oil；The feeding temperature of the molecularly distilled is 40 DEG C -45 DEG C, and sample introduction speed is 480-530mL/h, one section of evaporation temperature
Degree is 110 DEG C -115 DEG C, and dual circulation temperature is 60 DEG C -65 DEG C.
(4) it after crushing oenothera seed, is extracted using supercritical carbon dioxide, reuses molecularly distilled and extract, obtain base
Plinth oil；The temperature that the supercritical carbon dioxide extracts is 45 DEG C -48 DEG C, pressure 13.70MPa-17.80MPa, and the time is
50min-100min, the flow velocity of carbon dioxide are 25kg/h-35kg/h；The feeding temperature of the molecularly distilled is 40 DEG C -45
DEG C, sample introduction speed is 480-530mL/h, and one section of evaporating temperature is 110 DEG C -115 DEG C, and dual circulation temperature is 60 DEG C -65 DEG C；
(5) sandalwood essential oil for obtaining step 1, Pogostemon cablin essential that step 2 obtains, Lavender, cus-cus essential oil, step
The base oil that 3 obtained Bergamots and step 4 obtain is uniformly mixed, and obtains compound essential oil；In compound essential oil, each component
Quality proportioning are as follows: 20-25wt% Pogostemon cablin essential, 10-15wt% Bergamot, 20-25wt% Lavender, 5-
10wt% sandalwood essential oil, 1-3wt% cus-cus essential oil and 22-44wt% base oil.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109123938A (en) * | 2018-10-19 | 2019-01-04 | 魏佳 | The functional jewellery and its application method for having effects that calm mood silting of releiving, dredge |
| CN114191507A (en) * | 2020-09-17 | 2022-03-18 | 广东工业大学 | Anti-depression traditional Chinese medicine formula and anti-depression essential oil |
| CN116712358A (en) * | 2023-08-02 | 2023-09-08 | 江西瑞秀朗科技有限公司 | Compound essential oil for skin and pharmaceutical composition containing same |
-
2019
- 2019-06-27 CN CN201910567100.5A patent/CN110151609A/en not_active Withdrawn
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109123938A (en) * | 2018-10-19 | 2019-01-04 | 魏佳 | The functional jewellery and its application method for having effects that calm mood silting of releiving, dredge |
| CN114191507A (en) * | 2020-09-17 | 2022-03-18 | 广东工业大学 | Anti-depression traditional Chinese medicine formula and anti-depression essential oil |
| CN116712358A (en) * | 2023-08-02 | 2023-09-08 | 江西瑞秀朗科技有限公司 | Compound essential oil for skin and pharmaceutical composition containing same |
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