CN110141658A - A kind of novel prevention sow breeding peptase and preparation method - Google Patents
A kind of novel prevention sow breeding peptase and preparation method Download PDFInfo
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- CN110141658A CN110141658A CN201910498043.XA CN201910498043A CN110141658A CN 110141658 A CN110141658 A CN 110141658A CN 201910498043 A CN201910498043 A CN 201910498043A CN 110141658 A CN110141658 A CN 110141658A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
- A23K20/121—Heterocyclic compounds containing oxygen or sulfur as hetero atom
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
- A23K20/147—Polymeric derivatives, e.g. peptides or proteins
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/189—Enzymes
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
- C12Y207/01002—Glucokinase (2.7.1.2)
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Abstract
The invention discloses a kind of novel prevention sow breeding peptase and its preparation process, application method and purposes, novel prevention sow breeding peptase in the present invention is made of following components in percentage by weight: peptase 50-65%, subtilin 10-20%, isoflavones 10-20%, catalase 2-8%, surplus are carrier.The present invention passes through 0.1% addition feeding, and a cycle releasing sow is numerous to grow obstacle with what is be metabolized, by adjusting to uterine smooth muscle, reduces the antenatal impatience degree of sow, carrys out the control of shortening labor time within 3 hours；It is acted on by metabolic activation of the peptase to albumen and fat, accelerates the anabolism ability of liver, promote milking capacity enhancing；By adjusting to ovarian function, to sow corpus luteum ablation time control after wean in 2-3 days, effective percentage 93.3-96.9% is confirmed through multiple double blind experiments.
Description
Technical field
The present invention relates to cultivation industry field, a kind of novel prevention sow breeding peptase and preparation side are specifically related to
Method.
Background technique
In animal husbandry, pig-breeding is the maximum cultivation type of accounting, and in pig-breeding, sow breeding is most
One of important work.Sow breeds existing some problems and does not solve still at present, and main problem includes:
One, permanent corpus luteum causes sow periodically out of heat, and sow is caused to have to eliminate in advance, thus caused by sow
Mortality is up to 11.9%, in this regard, there is no targetedly solution in the industry.
Two, sow breeds and dysbolism, causes estrogen secretion insufficient, uterine myometrium is weary in reproductive process
Power, Normal labor 4-5 hours, up to 10 hours or more when uterine contractions fatigue, stages of labor is too long to directly result in bradytoia, and serious person makes
It is eliminated at difficult labour, bradytoia increases still birth rate and weak young rate or difficult labour is eliminated, and there is no effective solution at present.
Three, the conversion of sow energy is abnormal after reproduction, the decline of nursing period lactation amount, piglet slow growth.Weaned piglet stepmother
The ablation of pig corpus luteum is slow, and heat lags again.Sow breeding difficulty causes sow mortality averagely to rise 11.3%.
The measure taken in the industry at present is that, once heat obstacle occurs in discovery sow, oestrus of sow is slow, adds in feed
Chinese medicine pre-mixing agent promote the sexual maturity it is scattered, promote oestrus of sow.It promotes the sexual maturity scattered composition: Herba Epimedii, Radix Angelicae Sinensis, motherwort, Semen Cuscutae, actinolite.
It promotes the sexual maturity to dissipate and be added by 1% amount of feed, spice mixed feeding.Scattered additive amount of promoting the sexual maturity is big, and Chinese medicine odor is big and palatability is poor, causes 36% sow
Anorexia, the middle coarse absorption difference of drug fiber inspire feelings effective ratio and only have 4-6%, efficient very low, and not can effectively solve heat
Breeding problem.
The problems such as slow, stages of labor is too long is melted for permanent corpus luteum, corpus luteum, there is no definite effective scheme at present.
Summary of the invention
It is an object of the invention to overcome the shortcoming of above-mentioned traditional technology, it is female to provide a kind of specific aim prevention and treatment
Heat obstacle in pig breeding dysfunction, heat be slow, permanent corpus luteum, the problems such as corpus luteum ablation is slow, stages of labor is too long it is novel pre-
Anti- sow breeding peptase and its preparation process, application method and purposes.
The purpose of the present invention is what is reached by following technical measures:
A kind of novel prevention sow breeding peptase, it is characterised in that: be made of following components in percentage by weight:
Peptase 50-65%, subtilin 10-20%, isoflavones 10-20%, catalase 2-8%, surplus are carrier.
As a kind of specific preferred embodiment, it is made of following components in percentage by weight:
Peptase 61.5%, subtilin 15%, isoflavones 13.5%, catalase 5%, carrier 5%.
As a kind of specific preferred embodiment, it is made of following components in percentage by weight:
Peptase 50%, subtilin 20%, isoflavones 10%, catalase 8%, carrier 12 %.
As a kind of specific preferred embodiment, it is made of following components in percentage by weight:
Peptase 65%, subtilin 10%, isoflavones 20%, catalase 2%, carrier 3%.
As a preferred embodiment, the carrier is glucose.
A kind of preparation method of novel prevention sow breeding peptase, it is characterised in that: the following steps are included:
S1, stock are stocked up according to said components and weight percent；
S2, low-temperature mixed, all materials mix step by step under low temperature, antistatic environment；
The use of gained mixture is protected from light in S3, above-mentioned S2, antiultraviolet packaging is got product.
In particular, peptase is uniformly mixed by described be mixed into step by step with subtilin first, the different Huang of soybean is then added
Ketone is uniformly mixed, and catalase is then added and is uniformly mixed, and is eventually adding carrier and is uniformly mixed.
A kind of application method of novel prevention sow breeding peptase, it is characterised in that: breed above-mentioned novel prevention sow
For peptase according to 0.1% feed relative than addition, spice, feeding sow, feeding time is a cycle.
In particular, one period is to continue 18-20 days.
A kind of purposes of novel prevention sow breeding peptase, it is characterised in that: above-mentioned novel prevention sow is bred into peptase
For preventing and treating sow breeding difficulty.
The application tames the functional peptase that cultivation and fermentation is isolated by saccharomycete, is main effective with glucokinase
Ingredient, being confirmed by double blind experiment can be accurately in ovary, uterus, helicine artery epithelial cell, corpus luteum, on granular cell
There is expression.So as to effectively adjust ovarian function, obstacle is released, normal hormone in vivo is maintained to secrete, after sow application
(18-20 days) smooth heat in one cycle.
The action principle of novel prevention sow breeding peptase in the application:
By adjusting to uterine smooth muscle, the antenatal impatience degree of sow is reduced, carrying out the shortening labor time controls within 3 hours (just
Normal stages of labor 4-5 hour, up to 10 hours or more when uterine contractions fatigue, serious person causes difficult labour superseded).
It is acted on by metabolic activation of the peptase to albumen and fat, accelerates the anabolism ability of liver, promote lactation energy
Power enhancing.
By being adjusted to ovarian function, to sow corpus luteum ablation time control after wean in 2-3 days.
The application is the functional peptase of glucokinase using active constituent, passes through 0.1% addition and feeds, a cycle
The numerous obstacle of growing with metabolism of sow is released within (18-20 days), double blind experiment confirms effective percentage 93.3-96.9%.
By adopting the above-described technical solution, compared with prior art, the invention has the advantages that
The invention discloses a kind of novel prevention sow breeding peptase and its preparation process, application method and purposes, in the application
Novel prevention sow breeding peptase by 0.1% addition feeding, a cycle release sow it is numerous with metabolism grows obstacle, pass through
Uterine smooth muscle is adjusted, the antenatal impatience degree of sow is reduced, carrys out the control of shortening labor time within 3 hours；Pass through peptase pair
The effect of the metabolic activation of albumen and fat, accelerates the anabolism ability of liver, promotes milking capacity enhancing；By to ovary function
It is adjustable, to sow corpus luteum ablation time control after wean in 2-3 days, confirms effective percentage 93.3- through multiple double blind experiments
96.9%。
The invention will be further described With reference to embodiment.
Specific embodiment
Embodiment 1: a kind of novel prevention sow breeding peptase is made of following components in percentage by weight:
Peptase 61.5%, subtilin 15%, isoflavones 13.5%, catalase 5%, carrier 5%.
The carrier is glucose.
Embodiment 2: a kind of novel prevention sow breeding peptase is made of following components in percentage by weight:
Peptase 50%, subtilin 20%, isoflavones 10%, catalase 8%, carrier 12 %.
The carrier is glucose.
Embodiment 3: a kind of novel prevention sow breeding peptase is made of following components in percentage by weight:
Peptase 65%, subtilin 10%, isoflavones 20%, catalase 2%, carrier 3%.
The carrier is glucose.
A kind of embodiment 4: preparation method of novel prevention sow breeding peptase, comprising the following steps:
S1, stock, the component and weight percent to any one of 3 are stocked up in accordance with the above-mentioned embodiment 1；
S2, low-temperature mixed, all materials mix step by step under low temperature, antistatic environment；
The use of gained mixture is protected from light in S3, above-mentioned S2, antiultraviolet packaging is got product.
Wherein, it is mixed into described in S2 and is first uniformly mixed peptase with subtilin step by step, the different Huang of soybean is then added
Ketone is uniformly mixed, and catalase is then added and is uniformly mixed, and is eventually adding carrier and is uniformly mixed.
Embodiment 5: a kind of application method of novel prevention sow breeding peptase, by any one of above-described embodiment 1 to 3
Novel prevention sow breeding peptase according to 0.1% feed relative than addition, spice, feed sow, feeding time be a week
Phase.
One period is to continue 18-20 days.
Embodiment 6: a kind of purposes of novel prevention sow breeding peptase, by the new of any one of above-described embodiment 1 to 3
Type prevention sow breeding peptase is for preventing and treating sow breeding difficulty.
Claims (10)
1. a kind of novel prevention sow breeds peptase, it is characterised in that: be made of following components in percentage by weight:
Peptase 50-65%, subtilin 10-20%, isoflavones 10-20%, catalase 2-8%, surplus are carrier.
2. a kind of novel prevention sow according to claim 1 breeds peptase, it is characterised in that: by following weight percent
Component constitute:
Peptase 61.5%, subtilin 15%, isoflavones 13.5%, catalase 5%, carrier 5%.
3. a kind of novel prevention sow according to claim 1 breeds peptase, it is characterised in that: by following weight percent
Component constitute:
Peptase 50%, subtilin 20%, isoflavones 10%, catalase 8%, carrier 12 %.
4. a kind of novel prevention sow according to claim 1 breeds peptase, it is characterised in that: by following weight percent
Component constitute:
Peptase 65%, subtilin 10%, isoflavones 20%, catalase 2%, carrier 3%.
5. a kind of novel prevention sow according to claim 1 breeds peptase, it is characterised in that: the carrier is grape
Sugar.
6. a kind of preparation method of novel prevention sow breeding peptase, it is characterised in that: the following steps are included:
S1, stock are stocked up according to said components and weight percent；
S2, low-temperature mixed, all materials mix step by step under low temperature, antistatic environment.
7. a kind of preparation method of novel prevention sow breeding peptase according to claim 6, it is characterised in that: institute in S2
It states to be mixed into step by step and is first uniformly mixed peptase with subtilin, isoflavones is then added and is uniformly mixed, is then added
Catalase is uniformly mixed, and is eventually adding carrier and is uniformly mixed.
8. a kind of preparation method of novel prevention sow breeding peptase according to claim 6, it is characterised in that: also wrap
It includes:
The use of gained mixture is protected from light in S3, above-mentioned S2, antiultraviolet packaging is got product.
9. the application method of novel prevention sow breeding peptase described in a kind of claim 1, it is characterised in that: right
Ask novel prevention sow breeding peptase described in 1 according to 0.1% feed relative than addition, spice, feeding sow, feeding time
For a cycle, one period is to continue 18-20 days.
10. the purposes of novel prevention sow breeding peptase described in a kind of claim 1, it is characterised in that: by claim 1
Described in novel prevention sow breeding peptase for preventing and treating sow breeding difficulty.
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| CN201910498043.XA CN110141658A (en) | 2019-06-10 | 2019-06-10 | A kind of novel prevention sow breeding peptase and preparation method |
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| CN201910498043.XA CN110141658A (en) | 2019-06-10 | 2019-06-10 | A kind of novel prevention sow breeding peptase and preparation method |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111802524A (en) * | 2020-07-31 | 2020-10-23 | 山东利邦牧业股份有限公司 | Antioxidant free radical detoxifying promoting additive for sows |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101664120A (en) * | 2009-08-01 | 2010-03-10 | 遵义市金鼎农业科技有限公司 | Concentrated feed for lactating sows |
| CN107114584A (en) * | 2017-06-13 | 2017-09-01 | 湖南农业大学 | The feed addictive and its making application method of a kind of milking sow |
| CN109380616A (en) * | 2017-08-14 | 2019-02-26 | 河南爱诺生物科技有限公司 | A kind of feed addictive and preparation method thereof for improving sows farrowing ability and improving lactation amount |
-
2019
- 2019-06-10 CN CN201910498043.XA patent/CN110141658A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101664120A (en) * | 2009-08-01 | 2010-03-10 | 遵义市金鼎农业科技有限公司 | Concentrated feed for lactating sows |
| CN107114584A (en) * | 2017-06-13 | 2017-09-01 | 湖南农业大学 | The feed addictive and its making application method of a kind of milking sow |
| CN109380616A (en) * | 2017-08-14 | 2019-02-26 | 河南爱诺生物科技有限公司 | A kind of feed addictive and preparation method thereof for improving sows farrowing ability and improving lactation amount |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111802524A (en) * | 2020-07-31 | 2020-10-23 | 山东利邦牧业股份有限公司 | Antioxidant free radical detoxifying promoting additive for sows |
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Application publication date: 20190820 |