CN110140822A - A kind of Chinese herb feed additive and preparation method thereof improving Huainan Swine semen quality - Google Patents
A kind of Chinese herb feed additive and preparation method thereof improving Huainan Swine semen quality Download PDFInfo
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- A—HUMAN NECESSITIES
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Abstract
The present invention relates to a kind of Chinese herb feed additives and preparation method thereof for improving Huainan Swine semen quality.The Chinese herb feed additive is made of raw material from the following weight: 5-15 parts of Morinda officinalis, 5-15 parts of pyrola, 5-15 parts of rhizoma homalonemae, 10-30 parts of the rhizome of davallia, 6-10 parts of the root bark of Chinese wolf-berry, 10-20 parts of the shell of seaear, 10-15 parts of thizoma curculiginis, 8-15 parts of HERBA EPIMEDII, 10-20 parts of fructus alpiniae oxyphyllae, 15-20 parts of actinolite, 15-20 parts of pimpinella thellungiana, 6-15 parts of Paper mulberry Fruit, 15-25 parts of eclipta, 15-19 parts of the fruit of glossy privet, 7-15 parts of fructus lycii, 8-10 parts of Schisandra chinensis, 5-8 parts of nutmeg, 8-10 parts of raspberry, 3-5 parts of cortex cinnamomi, 3-5 parts of rhizoma zingiberis, 7-10 parts of fennel seeds, 10-20 parts of Rhizoma Atractylodis Macrocephalae, 15-22 parts of radix glycyrrhizae preparata.Each Chinese medicine material of the present invention cooperates, energy warming kidney and enhancing yang promotes gonopoiesis, through taking accurate measurement test card to the Huainan Swine for feeding Chinese herb feed additive of the present invention, additive of the present invention can be effectively improved Huainan Swine semen quality, Huainan Swine physiological function is improved, and preparation method step of the present invention is easy, it is easily operated, it is low in cost, gained Chinese herb feed additive stay in grade.
Description
Technical field
The present invention relates to Chinese medicine composition production technical fields, and in particular to a kind of medium-height grass for improving Huainan Swine semen quality
Medicine additive and preparation method thereof.
Background technique
Huainan Swine originates in Basin of Huaihe River, is distributed mainly on Gushi County, Guangshan County, Luoshan County, Xin County and the store in Henan Province
County.Dorsal body setae black, head is straight, and ear is sagging greatly, and figure is medium, and abdomen is sagging greatly, and leg stern owes plentiful, more sleeping systems.Huainan Swine is Henan Province
One of Local Excellent kind belongs to North China type, has farrowing more, reproductive capacity is strong, and resistance to crude feed, adaptable, lean meat percentage is higher, meat
Matter waits well excellent characteristics.
Under the higher and higher situation of pig raising industrial scale degree, the quality of boar fertility directly affects pig farm
Economic benefit, and the principal element of fertility is influenced for raising and nutrient imbalance.Considering nutrition to herd boar fertility
Influence when, need to consider various factors, the work of the quality, sperm of the yield and sperm of sexual desire, sperm including boar
Power etc..
Boar, to improve semen quality, is improved by adding some Chinese herb feed additives in diet by many farms
Utilization rate.Chinese herbal medicine mainly reconciles yin-yang, strengthening vital QI to eliminate pathogenic factors, and excitation Abwehrkraft des Koepers is to improve immunity function and breeding machine
Can, based on modern nutriology and thremmatology, the compound pure natural addictive that is developed into.In order to improve semen quality, mention
High boar utilization rate, Chinese herb feed additive become the hot spot of researchers' research.Application No. is 201410595250.4 hairs
In bright patent application, a kind of compound boar material of Chinese medicine for improving boar semen quality is disclosed, by adding into feedstuff main material
Chinese medicine additive improves the semen quality of boar.It is public application No. is in the application for a patent for invention of 201710018637 .7
Herd boar Chinese medicine health-care feed and preparation method thereof is opened, which includes that corn, dregs of beans, folium cortex eucommiae, herd boar are compound
Premix, compound probiotic, L-carnitine and compound Chinese medicine additive can be improved the immune function of herd boar, enhance endurance
And physical strength, improve herd boar semen volume, sperm concentration etc..But herd boar is not taken into account in foregoing invention patent application in sperm
Various nutritional needs such as formation, maturation, and the semen volume of herd boar, sperm concentration etc. are promoted limited.
Summary of the invention
The purpose of the present invention is to provide a kind of Chinese herb feed additives for improving Huainan Swine semen quality, can be improved kind of a Huaihe River
The immune function of southern pig boar enhances endurance and physical strength, enhances the sexual desire of boar, semen volume, the sperm for significantly improving boar are close
Degree, sperm motility rate, the breeding age of boar can be extended, and will not develop drug resistance, had no toxic side effect, have good reliability,
Safety.
To achieve the above object, the present invention adopts the following technical solutions:
A kind of Chinese herb feed additive improving Huainan Swine semen quality, which is characterized in that the Chinese herb feed additive is by following heavy
The raw material of amount part is made: 5-15 parts of Morinda officinalis, 5-15 parts of pyrola, 5-15 parts of rhizoma homalonemae, 10-30 parts of the rhizome of davallia, root bark of Chinese wolf-berry 6-
10 parts, 10-20 parts of the shell of seaear, 10-15 parts of thizoma curculiginis, 8-15 parts of HERBA EPIMEDII, 10-20 parts of fructus alpiniae oxyphyllae, 15-20 parts of actinolite, sheep it is red
Have a strong smell 15-20 parts, 6-15 parts of Paper mulberry Fruit, 15-25 parts of eclipta, 15-19 parts of the fruit of glossy privet, 7-15 parts of fructus lycii, 8-10 parts of Schisandra chinensis,
5-8 parts of nutmeg, 8-10 parts of raspberry, 3-5 parts of cortex cinnamomi, 3-5 parts of rhizoma zingiberis, 7-10 parts of fennel seeds, 10-20 parts of Rhizoma Atractylodis Macrocephalae, radix glycyrrhizae preparata
15-22 parts.
Preferably, the Chinese herb feed additive is made of raw material from the following weight: 8-15 parts of Morinda officinalis, pyrola 10-
15 parts, 8-15 parts of rhizoma homalonemae, 18-30 parts of the rhizome of davallia, 8-10 parts of the root bark of Chinese wolf-berry, 17-20 parts of the shell of seaear, 12-15 parts of thizoma curculiginis, HERBA EPIMEDII
10-15 parts, 10-18 parts of fructus alpiniae oxyphyllae, 18-20 parts of actinolite, 15-18 parts of pimpinella thellungiana, 10-15 parts of Paper mulberry Fruit, eclipta 15-18
Part, 15-17 parts of the fruit of glossy privet, 12-15 parts of fructus lycii, 8-10 parts of Schisandra chinensis, 5-8 parts of nutmeg, 8-10 parts of raspberry, cortex cinnamomi 3-5
Part, 3-5 parts of rhizoma zingiberis, 7-10 parts of fennel seeds, 10-14 parts of Rhizoma Atractylodis Macrocephalae, 15-18 parts of radix glycyrrhizae preparata.
Preferably, the Chinese herb feed additive is made of raw material from the following weight: 15 parts of Morinda officinalis, 15 parts of pyrola,
15 parts of rhizoma homalonemae, 30 parts of the rhizome of davallia, 10 parts of the root bark of Chinese wolf-berry, 20 parts of the shell of seaear, 15 parts of thizoma curculiginis, 15 parts of HERBA EPIMEDII, 10 parts of fructus alpiniae oxyphyllae, sun
Play 20 parts of stone, 15 parts of pimpinella thellungiana, 15 parts of Paper mulberry Fruit, 15 parts of eclipta, 15 parts of the fruit of glossy privet, 15 parts of fructus lycii, 8 parts of Schisandra chinensis, meat
8 parts of cardamom, 8 parts of raspberry, 5 parts of cortex cinnamomi, 3 parts of rhizoma zingiberis, 7 parts of fennel seeds, 10 parts of Rhizoma Atractylodis Macrocephalae, 15 parts of radix glycyrrhizae preparata.
The present invention also provides a kind of preparation method of Chinese herb feed additive for improving Huainan Swine semen quality, feature exists
In comprising the following steps:
SS01: each raw material of traditional Chinese medicinal components is accurately weighed by formula ratio, drying and crushing after cleaning, and crosses 10 meshes, and gained powder is standby
With；
SS02: gained powder is impregnated in ultrasonic oscillation instrument with the deionized water of 5-8 times of quality, ultrasound shake at 40-55 DEG C
Swing 1-2 h, filter liquid A is spare；
SS03: extracting 2-4 h for 75% alcohol reflux of the powder after immersion, and when alcohol content is up to 60% ~ 65%, refrigeration is stood,
Ethyl alcohol is recycled, gained filtrate carries out ultrafiltration using 0.65um miillpore filter, filtrate I obtained, by the above-mentioned powder to flow back by same
Method refluxing extraction and ultrafiltration again, obtains filtrate II, merging filtrate I, II obtain liquid B；
SS04: merging liquid A and liquid B, by precise filtering device, removes solid impurity and obtains clear filtrate, is concentrated into opposite
Density is about 1.17-1.20, and in 70 DEG C of water bath methods, it is spare to obtain medicinal extract；
SS05: being added the surfactant of medicinal extract quality 1%, the dextrin of medicinal extract quality 5% in above-mentioned medicinal extract, spraying after mixing evenly
It dry, pulverize and be mixed and made into granule, control grain diameter is not more than 0.5mm, packs to obtain the final product.
Preferably, ultrasonic temperature is 45 DEG C -50 DEG C in step SS02.
Preferably, extraction time is 3h or more in step SS03, and alcohol content recycles ethyl alcohol when being 65%.
The present invention provides a kind of Chinese herb feed additive and preparation method thereof for improving Huainan Swine semen quality, with the prior art
Compared to having the advantages that
(1) present invention using the rhizome of davallia, actinolite, the shell of seaear, fructus lycii, HERBA EPIMEDII, Schisandra chinensis, rhizoma homalonemae as main material,
Chinese medicine composition obtained has effects that tonifying kidney and strengthening yang, promoting circulation of blood and enriching blood, regulating qi-flowing for strengthening spleen, solves the frequent semen collection of Huainan Swine and causes sexual desire
The problem of reduction, semen quality decline, wherein fructus lycii, HERBA EPIMEDII, the shell of seaear, Schisandra chinensis cooperate, can warming kidney and enhancing yang, rush
Into gonopoiesis, it is effectively improved semen quality, improves Huainan Swine physiological function.
(2) present invention uses the multiple means such as immersion, sonic oscillation, refluxing extraction, effectively extracts raw material active constituent,
And by the scientific and reasonable adjusting to design parameter in the preparation process such as grain diameter, ultrasonic temperature, effectively increase activity
Ingredient dissolution rate has ensured the performance of product efficacy.Preparation method step of the present invention is easy, easily operated, low in cost, gained
Chinese herb feed additive stay in grade.
Specific embodiment
In order to make the object, technical scheme and advantages of the embodiment of the invention clearer, below with reference to the embodiment of the present invention pair
Technical solution in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is a part of the invention
Embodiment, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art are not making wound
Every other embodiment obtained under the premise of the property made labour, shall fall within the protection scope of the present invention.
Chinese herb feed additive safety testing
The present invention has carried out long term toxicity test to the Chinese herb feed additive for improving Huainan Swine semen quality first.Select SD
Rat is divided into 4 groups (half male and half females) at random after 5 days adaptive feedings, and every group each 20, A group feeds this hair daily
Bright Chinese herb feed additive, scale of feeding 100g/kg, continuous feeding 3 months；B group feeds Chinese herb feed additive of the present invention daily, raises
The amount of feeding is 80g/kg, continuous feeding 3 months, while the mouse grain of feeding 20g/kg daily；Feeding Chinese herbal medicine of the present invention adds C group daily
Add agent, scale of feeding 60g/kg, continuous feeding 3 months, while the mouse grain of feeding 40g/kg daily；D group feeds 100g/kg daily
Mouse grain, continuous feeding 3 months.The results are shown in Table 1 for the observation of SD rat during feeding.
SD rat observes result during table 1 is fed
| Feeding quantity/only | Morbidity quantity/only | The dead quantity/only | |
| A group | 20 | 0 | 0 |
| B group | 20 | 0 | 0 |
| C group | 20 | 0 | 0 |
| D group | 20 | 0 | 0 |
Seen from table 1, using the SD rat of Chinese herb feed additive of the present invention feeding and the SD rat using the feeding of common mouse grain
Incidence and death condition do not occur notable difference, and each group SD rat state of mind, appetite etc. are equal during feeding
Do not occur obvious exception, it is seen that Chinese herb feed additive good security of the present invention.
Embodiment 1
A kind of Chinese herb feed additive improving Huainan Swine semen quality, which is characterized in that the Chinese medicine composition is by following weight
The raw material of part is made: 10 parts of Morinda officinalis, 10 parts of pyrola, 10 parts of rhizoma homalonemae, 25 parts of the rhizome of davallia, 8 parts of the root bark of Chinese wolf-berry, the shell of seaear 15
Part, 13 parts of thizoma curculiginis, 10 parts of HERBA EPIMEDII, 15 parts of fructus alpiniae oxyphyllae, 17 parts of actinolite, 20 parts of pimpinella thellungiana, 12 parts of Paper mulberry Fruit, eclipta 20
Part, 18 parts of the fruit of glossy privet, 8 parts of fructus lycii, 10 parts of Schisandra chinensis, 5 parts of nutmeg, 10 parts of raspberry, 5 parts of cortex cinnamomi, 3 parts of rhizoma zingiberis, fennel fruit
Fragrant 7 parts, 15 parts of Rhizoma Atractylodis Macrocephalae, 20 parts of radix glycyrrhizae preparata.
The preparation method of the Chinese herb feed additive comprises the following steps:
SS01: each raw material of traditional Chinese medicinal components is accurately weighed by formula ratio, drying and crushing after cleaning, and crosses 10 meshes, and gained powder is standby
With；
SS02: gained powder being impregnated in ultrasonic oscillation instrument with the deionized water of 6 times of quality, ultrasonic vibration 2h at 45 DEG C,
Filter liquid A is spare；
SS03: 75% alcohol reflux of the powder after immersion is extracted into 3 h, when alcohol content is up to 65%, refrigeration is stood, and recycles second
Alcohol, gained filtrate carry out ultrafiltration using 0.65um miillpore filter, obtain filtrate I, in the same way again by the above-mentioned powder to flow back
Secondary refluxing extraction, obtains filtrate II, and merging filtrate I, II obtain liquid B；
SS04: merging liquid A and liquid B, by precise filtering device, removes solid impurity and obtains clear filtrate, is concentrated into opposite
Density is about 1.20, and in 70 DEG C of water bath methods, it is spare to obtain medicinal extract；
SS05: being added the surfactant of medicinal extract quality 1%, the dextrin of medicinal extract quality 5% in above-mentioned medicinal extract, spraying after mixing evenly
It dry, pulverize and be mixed and made into granule, control grain diameter is not more than 0.5mm, packs to obtain the final product.
Embodiment 2
A kind of Chinese herb feed additive improving Huainan Swine semen quality, which is characterized in that the Chinese medicine composition is by following weight
The raw material of part is made: 15 parts of Morinda officinalis, 15 parts of pyrola, 15 parts of rhizoma homalonemae, 30 parts of the rhizome of davallia, 10 parts of the root bark of Chinese wolf-berry, the shell of seaear 20
Part, 15 parts of thizoma curculiginis, 15 parts of HERBA EPIMEDII, 10 parts of fructus alpiniae oxyphyllae, 20 parts of actinolite, 15 parts of pimpinella thellungiana, 15 parts of Paper mulberry Fruit, eclipta 15
Part, 15 parts of the fruit of glossy privet, 15 parts of fructus lycii, 8 parts of Schisandra chinensis, 8 parts of nutmeg, 8 parts of raspberry, 5 parts of cortex cinnamomi, 3 parts of rhizoma zingiberis, fennel seeds
7 parts, 10 parts of Rhizoma Atractylodis Macrocephalae, 15 parts of radix glycyrrhizae preparata.
The preparation method of the Chinese herb feed additive comprises the following steps:
SS01: each raw material of traditional Chinese medicinal components is accurately weighed by formula ratio, drying and crushing after cleaning, and crosses 10 meshes, and gained powder is standby
With；
SS02: gained powder being impregnated in ultrasonic oscillation instrument with the deionized water of 6 times of quality, ultrasonic vibration 2h at 45 DEG C,
Filter liquid A is spare；
SS03: 75% alcohol reflux of the powder after immersion is extracted into 3 h, when alcohol content is up to 65%, refrigeration is stood, and recycles second
Alcohol, gained filtrate carry out ultrafiltration using 0.65um miillpore filter, obtain filtrate I, in the same way again by the above-mentioned powder to flow back
Secondary refluxing extraction, obtains filtrate II, and merging filtrate I, II obtain liquid B；
SS04: merging liquid A and liquid B, by precise filtering device, removes solid impurity and obtains clear filtrate, is concentrated into opposite
Density is about 1.20, and in 70 DEG C of water bath methods, it is spare to obtain medicinal extract；
SS05: being added the surfactant of medicinal extract quality 1%, the dextrin of medicinal extract quality 5% in above-mentioned medicinal extract, spraying after mixing evenly
It dry, pulverize and be mixed and made into granule, control grain diameter is not more than 0.5mm, packs to obtain the final product.
Comparative example 1
A kind of Chinese herb feed additive improving Huainan Swine semen quality, which is characterized in that the Chinese medicine composition is by following weight
The raw material of part is made: 20 parts of Morinda officinalis, 20 parts of pyrola, 20 parts of rhizoma homalonemae, 20 parts of the rhizome of davallia, 15 parts of the root bark of Chinese wolf-berry, the shell of seaear 20
Part, 5 parts of thizoma curculiginis, 5 parts of HERBA EPIMEDII, 5 parts of fructus alpiniae oxyphyllae, 18 parts of actinolite, 10 parts of pimpinella thellungiana, 3 parts of Paper mulberry Fruit, 5 parts of eclipta, glossy privet
Son 25 parts, 20 parts of fructus lycii, 5 parts of Schisandra chinensis, 2 parts of nutmeg, 3 parts of raspberry, 10 parts of cortex cinnamomi, 10 parts of rhizoma zingiberis, 10 parts of fennel seeds,
10 parts of Rhizoma Atractylodis Macrocephalae, 25 parts of radix glycyrrhizae preparata
1 Chinese herb feed additive preparation method of documents is same as Example 1.
Comparative example 2
A kind of Chinese herb feed additive improving Huainan Swine semen quality, each raw material composition and its content are same as Example 1.
2 Chinese herb feed additive preparation method of documents comprises the following steps:
SS01: each raw material of traditional Chinese medicinal components is accurately weighed by formula ratio, drying and crushing after cleaning, and crosses 10 meshes, and gained powder is standby
With；
SS02: gained powder being impregnated in ultrasonic oscillation instrument with the deionized water of 6 times of quality, ultrasonic vibration 2h at 60 DEG C,
Filter liquid A is spare；
SS03: 75% alcohol reflux of the powder after immersion is extracted into 3 h, when alcohol content is up to 65%, refrigeration is stood, and recycles second
Alcohol, gained filtrate carry out ultrafiltration using 0.65um miillpore filter, obtain filtrate I, in the same way again by the above-mentioned powder to flow back
Secondary refluxing extraction, obtains filtrate II, and merging filtrate I, II obtain liquid B；
SS04: merging liquid A and liquid B, by precise filtering device, removes solid impurity and obtains clear filtrate, is concentrated into opposite
Density is about 1.20, and in 70 DEG C of water bath methods, it is spare to obtain medicinal extract；
SS05: being added the surfactant of medicinal extract quality 1%, the dextrin of medicinal extract quality 5% in above-mentioned medicinal extract, spraying after mixing evenly
It dry, pulverize and be mixed and made into granule, control grain diameter is not more than 0.5mm, packs to obtain the final product.
Comparative example 3
A kind of Chinese herb feed additive improving Huainan Swine semen quality, which is characterized in that the Chinese medicine composition is by following weight
Part raw material be made: 10 parts of Morinda officinalis, 10 parts of rhizoma homalonemae, 8 parts of the root bark of Chinese wolf-berry, 25 parts of the shell of seaear, 13 parts of thizoma curculiginis, 20 parts of HERBA EPIMEDII,
17 parts of actinolite, 25 parts of pimpinella thellungiana, 12 parts of Paper mulberry Fruit, 20 parts of eclipta, 18 parts of the fruit of glossy privet, 23 parts of fructus lycii, 10 parts of Schisandra chinensis,
15 parts of nutmeg, 20 parts of raspberry, 13 parts of rhizoma zingiberis, 12 parts of fennel seeds, 15 parts of Rhizoma Atractylodis Macrocephalae.
3 Chinese herb feed additive preparation method of documents is same as Example 1.
Chinese herb feed additive efficacy validation
It selects Gushi County Huainan breeding pig farm to grow up herd boar 54, is randomly divided into 6 groups, every group 9.Every group adds except what is used
Add agent different outer, other settings such as Feeding time, feeding volume are all the same, according to said method continuous feeding 8 weeks, semen collection 2 times in the 9th week.
Wherein, A group mixes 1 Chinese herb feed additive of embodiment in pannage, and incorporation is the 1.5% of pannage weight；B group is raised in pig
2 Chinese herb feed additive of embodiment is mixed in material, incorporation is the 1.5% of pannage weight；C group mixes comparative example in pannage
1 Chinese herb feed additive, incorporation are the 1.5% of pannage weight；D group mixes 2 Chinese herb feed additive of comparative example in pannage,
Incorporation is the 1.5% of pannage weight；E group mixes 3 Chinese herb feed additive of comparative example in pannage, and incorporation is pannage
The 1.5% common daily ration of feeding of weight；F group is blank control group, and feeding organizes identical pannage with other, but in not mixing
Chinese herbal medicine additive agent.
Influence by following criterion validation Chinese herb feed additive of the present invention to Huainan Swine herd boar semen quality.Color is gentle
Taste: normal semen is milky or canescence, slightly fishy smell.If any in yellow, pale red, yellowish-brown and stink it is any then
It is unqualified；PH of semen: can be measured with pH value test paper, and normal semen is in alkalescent or neutrality, pH value in 7.0-7.8,
PH value > 7.8 are unqualified；Sperm motility rate: using hanging drop preparation inspection technique, sperm be heated to 35-37 DEG C in constant temperature objective table,
Sperm is observed under 100-400 power microscope, percentage shared by the sperm of straight ahead movement is the motility rate for indicating sperm, fresh
The sperm of acquisition and the sperm motility rate of diluted fresh must not require lower than 0 .7, and it is living to save the sperm preoperation inspection above for 24 hours
Rate must not be lower than 0.6, otherwise be unqualified；Sperm concentration: referring to sperm count contained in every milliliter of sperm, is determining extension rate
Important indicator, with blood cell counting plate carry out count or with sperm densimeter measurement；Rate of teratosperm: abnormal rate refers to abnormal smart
The percentage of son is determined using microscopic observation, after semen smear, dyeing, is observed under 400-600 power microscope, is calculated
Defective sperm accounts for the percentage of counted sperm sum.
Each group semen quality is as shown in table 2 after feeding 8 weeks, wherein contained data are obtained the average value of sample by 2 semen collections.
Each group semen quality after table 2 is fed 8 weeks
| A group | B group | C group | D group | E group | F group | |
| Color smell | Milky, slightly fishy smell | Milky, slightly fishy smell | Milky, slightly fishy smell | Milky, slightly fishy smell | Milky, slightly fishy smell | Milky, slightly fishy smell |
| PH value | 7.3 | 7.2 | 7.3 | 7.3 | 7.1 | 7.8 |
| Sperm motility rate/% | 92.23±3.13 | 93.58±2.98 | 81.67±2.05 | 82.03±2.24 | 75.27±1.85 | 80.76±2.45 |
| Sperm concentration/108·ml-1 | 4.32±0.25 | 4.86±0.28 | 3.62±0.21 | 3.58±0.20 | 2.38±0.13 | 3.35±0.21 |
| Rate of teratosperm/% | 4.2±0.4 | 3.6±0.3 | 4.5±0.3 | 4.4±0.2 | 6.7±0.3 | 4.9±0.4 |
The Huainan Swine for the feed feeding for mixing Chinese herb feed additive of the present invention, semen quality are used it can be seen from 2 result of table
It is substantially better than blank control group and comparative example, sperm motility rate, sperm concentration significantly improve and rate of teratosperm significantly reduces.
From A group B group result it is found that each raw material of Chinese herb feed additive of the present invention has important shadow to the final effect of additive
It rings, sperm quality is promoted using the additive of optimum embodiment 2 the most significant.And C group Chinese herb feed additive raw material components are not
Within the scope of the present invention, even if the additive raw material total amount is identical as A group, but it obviously compares A to the promotion effect of sperm quality
Group is much smaller.
For A group compared with E group, difference is only that E group has lacked several taste Chinese medicine materials compared with A group, can from the two curative effect
It arrives, even if E group Chinese herb feed additive does not promote effect, sperm quality to sperm quality in the identical situation of Chinese medicine total amount
Even it is worse than not mixing the blank control group of Chinese herb feed additive, due to Chinese prescription be an organic whole, raw material and its
The slight variation of dosage may cause the greatest differences of curative effect, and the present inventor, creatively will be of the invention by studying for a long period of time
Each Chinese herbal medicine combination, achieves significantly superior therapeutic effect.
For A group compared with D group, difference is only that the sonic oscillation temperature of D group is 60 DEG C and A group is 45 DEG C.By 2 result of table
It is found that not the higher the better for sonic oscillation temperature, but there are a reasonable temperature section, in this section, typical temperature is got over
High effective component of chinese medicine dissolution is more thorough rapidly, however is more than the temperature range, and high temperature is easy instead so that effective component is lost
It is living, cause drug effect to be decreased obviously.Therefore, the present inventor makes the creative labor by studying for a long period of time and has found the suitable present invention
The sonic oscillation temperature of traditional Chinese medicine ingredients, effective ingredient dissolution is thoroughly rapid, and curative effect of medication is excellent.
The foregoing is merely presently preferred embodiments of the present invention, is not intended to limit the invention, it is all in spirit of the invention and
Made any modifications, equivalent replacements, and improvements etc., should all be included in the protection scope of the present invention within principle.
Claims (6)
1. a kind of Chinese herb feed additive for improving Huainan Swine semen quality, which is characterized in that the Chinese herb feed additive is by following
The raw material of parts by weight is made: 5-15 parts of Morinda officinalis, 5-15 parts of pyrola, 5-15 parts of rhizoma homalonemae, 10-30 parts of the rhizome of davallia, the root bark of Chinese wolf-berry
6-10 parts, 10-20 parts of the shell of seaear, 10-15 parts of thizoma curculiginis, 8-15 parts of HERBA EPIMEDII, 10-20 parts of fructus alpiniae oxyphyllae, 15-20 parts of actinolite, sheep
Red have a strong smell 15-20 parts, 6-15 parts of Paper mulberry Fruit, 15-25 parts of eclipta, 15-19 parts of the fruit of glossy privet, 7-15 parts of fructus lycii, Schisandra chinensis 8-10
Part, 5-8 parts of nutmeg, 8-10 parts of raspberry, 3-5 parts of cortex cinnamomi, 3-5 parts of rhizoma zingiberis, 7-10 parts of fennel seeds, 10-20 parts of Rhizoma Atractylodis Macrocephalae, toast are sweet
It is 15-22 parts careless.
2. improving the Chinese herb feed additive of Huainan Swine semen quality as described in claim 1, it is characterised in that: the Chinese herbal medicine
Additive is made of raw material from the following weight: 8-15 parts of Morinda officinalis, 10-15 parts of pyrola, 8-15 parts of rhizoma homalonemae, the rhizome of davallia
18-30 parts, 8-10 parts of the root bark of Chinese wolf-berry, 17-20 parts of the shell of seaear, 12-15 parts of thizoma curculiginis, 10-15 parts of HERBA EPIMEDII, 10-18 parts of fructus alpiniae oxyphyllae, sun
Play stone 18-20 parts, 15-18 parts of pimpinella thellungiana, 10-15 parts of Paper mulberry Fruit, 15-18 parts of eclipta, 15-17 parts of the fruit of glossy privet, fructus lycii 12-
15 parts, 8-10 parts of Schisandra chinensis, 5-8 parts of nutmeg, 8-10 parts of raspberry, 3-5 parts of cortex cinnamomi, 3-5 parts of rhizoma zingiberis, 7-10 parts of fennel seeds,
10-14 parts of Rhizoma Atractylodis Macrocephalae, 15-18 parts of radix glycyrrhizae preparata.
3. improving the Chinese herb feed additive of Huainan Swine semen quality as described in claim 1, it is characterised in that: the Chinese herbal medicine
Additive is made of raw material from the following weight: 15 parts of Morinda officinalis, 15 parts of pyrola, 15 parts of rhizoma homalonemae, 30 parts of the rhizome of davallia, bone
10 parts of skin, 20 parts of the shell of seaear, 15 parts of thizoma curculiginis, 15 parts of HERBA EPIMEDII, 10 parts of fructus alpiniae oxyphyllae, 20 parts of actinolite, 15 parts of pimpinella thellungiana, Paper mulberry Fruit
15 parts, 15 parts of eclipta, 15 parts of the fruit of glossy privet, 15 parts of fructus lycii, 8 parts of Schisandra chinensis, 8 parts of nutmeg, 8 parts of raspberry, 5 parts of cortex cinnamomi,
3 parts of rhizoma zingiberis, 7 parts of fennel seeds, 10 parts of Rhizoma Atractylodis Macrocephalae, 15 parts of radix glycyrrhizae preparata.
4. a kind of preparation side of Chinese herb feed additive for improving Huainan Swine semen quality according to claim 1-3
Method, which is characterized in that comprise the following steps:
SS01: each raw material of traditional Chinese medicinal components is accurately weighed by formula ratio, drying and crushing after cleaning, and crosses 10 meshes, and gained powder is standby
With；
SS02: gained powder is impregnated in ultrasonic oscillation instrument with the deionized water of 5-8 times of quality, ultrasound shake at 40-55 DEG C
Swing 1-2 h, filter liquid A is spare；
SS03: extracting 2-4 h for 75% alcohol reflux of the powder after immersion, and when alcohol content is up to 60% ~ 65%, refrigeration is stood,
Ethyl alcohol is recycled, gained filtrate carries out ultrafiltration using 0.65um miillpore filter, filtrate I obtained, by the above-mentioned powder to flow back by same
Method refluxing extraction and ultrafiltration again, obtains filtrate II, it is spare that merging filtrate I, II obtain liquid B；
SS04: merging liquid A and liquid B, by precise filtering device, removes solid impurity and obtains clear filtrate, is concentrated into opposite
Density is about 1.17-1.20, and in 70 DEG C of water bath methods, it is spare to obtain medicinal extract；
SS05: being added the surfactant of medicinal extract quality 1%, the dextrin of medicinal extract quality 5% in above-mentioned medicinal extract, spraying after mixing evenly
It dry, pulverize and be mixed and made into granule, control grain diameter is not more than 0.5mm, packs to obtain the final product.
5. improving the preparation method of the Chinese herb feed additive of Huainan Swine semen quality as claimed in claim 4, it is characterised in that:
Ultrasonic temperature is 45 DEG C -50 DEG C in step SS02.
6. improving the preparation method of the Chinese herb feed additive of Huainan Swine semen quality as claimed in claim 5, it is characterised in that:
Extraction time is 3h or more in step SS03, and alcohol content recycles ethyl alcohol when being 65%.
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