CN110123960A - A kind of Chinese medicine composition for treating hand-foot-and-mouth disease, Chinese medical extract and preparation method thereof and dosage form - Google Patents

A kind of Chinese medicine composition for treating hand-foot-and-mouth disease, Chinese medical extract and preparation method thereof and dosage form Download PDF

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CN110123960A
CN110123960A CN201910115494.0A CN201910115494A CN110123960A CN 110123960 A CN110123960 A CN 110123960A CN 201910115494 A CN201910115494 A CN 201910115494A CN 110123960 A CN110123960 A CN 110123960A
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/35Caprifoliaceae (Honeysuckle family)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/532Agastache, e.g. giant hyssop
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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Abstract

The present invention is a kind of Chinese medicine composition for treating hand-foot-and-mouth disease, Chinese medical extract and preparation method thereof technical field.The Chinese medicine composition is made of oriental wormwood, chrysanthemum, folium isatidis, Radix Isatidis, lophatherum gracile, rhizoma atractylodis, lotus leaf, the root of Dahurain angelica, honeysuckle flower, wrinkled giant hyssop, Radix Glycyrrhizae.The Chinese medical extract is to filter resulting decocting liquid after Chinese medicine composition is carried out decocting.Chinese medicine composition and extract of the invention has clearing heat and detoxicating, cool blood, dampness elimination, the effect of toxin expelling.Specially control the compositions useful of hand-foot-and-mouth disease.

Description

A kind of Chinese medicine composition for treating hand-foot-and-mouth disease, Chinese medical extract and preparation method thereof And dosage form
Technical field
The invention belongs to Chinese materia medica preparation extremely preparation method technical fields.Specifically a kind of Chinese medicine for treating hand-foot-and-mouth disease Combination of traditional Chinese medicine extract and preparation method and dosage form.Face disease application safely and effectively, belongs to innovative technical field of Chinese medicine.
Background technique
Hand-foot-and-mouth disease is a kind of small childhood heresy disease of infectivity caused by damp evil, and spring and summer is easily sent out.
Symptom is wet and thermally-induced oral lesions, and hand plays vesicle, and foot plays vesicle, itches, the disease of low-heat.
Summary of the invention
We are with rear significant in efficacy;Two children while onset, one to county town is treated 7 days, spends more than 6,000;An example exists Here treatment, more than ten yuan are recovered, and treatment time 3 days.So technology should be promoted.
Our good effect, has no toxic side effect, and the curative effect for allowing more children to have obtained palliates the agonizing sufferings, and discloses a kind of pre- Anti- and treatment Chinese medicine composition, Chinese medical extract and dosage form.
It is another object of the present invention to disclose the preparation method of above-mentioned Chinese medical extract.
Technical scheme is as follows:
A kind of Chinese medicine composition preventing and treating hand-foot-and-mouth disease, wherein the Chinese medicine composition is by following weight parts Bulk pharmaceutical chemicals composition: be with -10 years old 2 years old children it is more, just by this measure about feelings plus-minus: 5-10 parts of oriental wormwood, 5-10 parts of chrysanthemum, smalt 5-10 parts of leaf, 5-10 parts of Radix Isatidis, 5-10 parts of wrinkled giant hyssop, 5-10 parts of lophatherum gracile, 8-10 parts of rhizoma atractylodis, 5-10 parts of lotus leaf, root of Dahurain angelica 6-8 Part, 5-8 parts of honeysuckle flower, 6-8 parts of Radix Glycyrrhizae.
A kind of Chinese medicine composition preventing and treating hand-foot-and-mouth disease, wherein 10 parts of oriental wormwood, 5 parts of chrysanthemum, 5 parts of folium isatidis, 5 parts of Radix Isatidis, 5 parts of wrinkled giant hyssop, 5 parts of lophatherum gracile, 5 parts of rhizoma atractylodis, 5 parts of lotus leaf, 5 parts of the root of Dahurain angelica, 5 parts of honeysuckle flower, 3 parts of Radix Glycyrrhizae.
Each parts by weight of raw materials described in its feature of the Chinese medicine composition according to the 1 of claim and 2 are as follows: 6-8 parts of oriental wormwood, 3-6 parts of chrysanthemum, 3-6 parts of folium isatidis, 6-8 parts of Radix Isatidis, 3-6 parts of wrinkled giant hyssop, 3-6 parts of lophatherum gracile, 3-6 parts of rhizoma atractylodis, 3-6 parts of rhizoma atractylodis, 3-6 parts of lotus leaf, 3-6 parts of the root of Dahurain angelica, 3-6 parts of honeysuckle flower, 2-3 parts of Radix Glycyrrhizae.
A kind of Chinese medical extract that treating brothers mouthful wherein the Chinese medical extract by technology any in above-mentioned technical proposal The preparation of Chinese medicine composition described in scheme.And it can be added and subtracted according to child age.
The preparation method of Chinese medical extract described in above-mentioned technical proposal, wherein the preparation method is by the Chinese medicine Component decocting, with cold water soak 30 minutes of 4 times, water was decocted 15 minutes after opening, and repeatedly two hours drank once on 1st, and one day one Agent, company drink two doses.(because of children particularity)
The dosage form of Chinese medical extract as described in the above technical scheme preparation, wherein its Chinese medicine as described in above scheme Extract and pharmaceutically acceptable carrier composition.The dosage form includes water decoction, mass production particle electuary, oral solution or water Ball.
The effect of each bulk pharmaceutical chemicals are had in the main side of the present invention:
Oriental wormwood effect: clearing heat and promoting diuresis, removing jaundice, cholagogue protect liver.For various diseases in the liver and gallbladder;All kinds of illnesss of damp evil and folder, Eczema.
The effect of chrysanthemum: clearing liver and improving vision, clearing heat and detoxicating.For canker sore;Eyes are fuzzy, inflamed eyes.
The effect of folium isatidis: clearing heat and detoxicating, blood cooling and ecchymoses removing;Strengthen immunity.For ecchymosis, jaundice, dysentery, erysipelas.
The effect of Radix Isatidis: clearing heat and detoxicating, blood cooling and ecchymoses removing.It catches a cold for heat toxin, sore-throat, various sores.
The effect of wrinkled giant hyssop: driving away summer heat inducing diaphoresis, removing dampness to restore normal functioning of the stomach.For summer-heat damp cold, gastrointestinal disharmony is suffered from vomiting and diarrhoea, cholera.
The effect of lophatherum gracile: clearing heat and relieving fidgetness, diuresis;Clearing away damp-heat.For damp evil diuresis.
The effect of rhizoma atractylodis: invigorating the spleen, dampness removing.Improving eyesight.Suitable for the spleen and stomach being stranded by dampness;Arthralgia, rheumatic arthritis.For urine It is unfavorable, oedema, the damp and hot stranguria with turbid discharge of phlegm retention.
The effect of lotus leaf: clearing away summerheat, sending up the lucid YANG, cool blood, diuresis is treating stranguria.For heat-clearing diuresis.
The effect of root of Dahurain angelica: wind-damp dispelling, resolving sputum, apocenosis of invigorating blood circulation.For exogenous headache;Various sores.
The effect of honeysuckle flower: clearing heat and detoxicating, dispelling wind and heat from the body removes heat from the blood and relieve diarrhea.For three burnt heat;Various sores.
The effect of Radix Glycyrrhizae: removing toxic substances, cough-relieving, mediation property of medicine.For trembling with fear, productive cough is coughed;Solve all poisoning of drug elements;Mediation property of medicine.
The invention has the following advantages:
Chinese medicine composition and extract of the invention has clearing heat and detoxicating, expels pathogenic wind from the body surface, cool blood, clearing damp rash, the work for sore of dispelling With.Safely and effectively, safety is taken medicine, simple and easy.The generality of prevention and treatment is that the common of infection prevention hand-foot-mouth disease has Efficacious prescriptions agent.
Specific embodiment
In order to make the technical solution of the present invention easy to understand, the present invention is made further below in conjunction with specific embodiment It is bright.
Embodiment 1: the preparation of Chinese medicine composition:
8 parts of oriental wormwood, 8 parts of chrysanthemum, 8 parts of folium isatidis, 8 parts of Radix Isatidis, 10 parts of wrinkled giant hyssop, 8 parts of lophatherum gracile, 8 parts of rhizoma atractylodis, lotus leaf 8 Point, 8 parts of the root of Dahurain angelica, 8 parts of honeysuckle flower, 5 parts of Radix Glycyrrhizae.
Embodiment 2: the preparation of Chinese medicine composition:
8 parts of oriental wormwood, 6 parts of chrysanthemum, 6 parts of folium isatidis, 6 parts of Radix Isatidis, 6 parts of wrinkled giant hyssop, 6 parts of lophatherum gracile, 6 parts of roots of Dahurain angelica 6 of rhizoma atractylodis Part, 6 parts of honeysuckle flower, 3 parts of Radix Glycyrrhizae.
Embodiment 3: the preparation of Chinese medicine composition:
7 parts of oriental wormwood, 4 parts of chrysanthemum, 4 parts of folium isatidis, 4 parts of Radix Isatidis, 4 parts of wrinkled giant hyssop, 4 parts of lophatherum gracile, 4 parts of rhizoma atractylodis, lotus leaf 4 Part, 4 parts of the root of Dahurain angelica, 4 parts of honeysuckle flower, 2 parts of Radix Glycyrrhizae.
Embodiment 4: the preparation of Chinese medicine composition:
The resulting Chinese medicine composition of Example 1-3 is first used cold water soak 10 minutes, is boiled with strong fire, and mild fire decocts 15 points slowly Clock obtains Chinese medical extract (gently saturating medicine administered to bring out the cold should not be decocted long).
Chinese traditional medicine composition or extract of the invention, should be enough by our crude drug in whole foot medicine when producing by batch, then with this The universal method water decoction convenient oral in field.It produces by batch and is made into particle, be condensed into oral solution, honeyed bolus, tablet.
Illustrate beneficial effect possessed by drug of the present invention below by way of clinical practice case, which is this hair The clinical observation on the therapeutic effect of bright drug.
Chen children, 2 years old, brothers mouthful were white vesicle, low-heat, do not feel like eating.Dose improves, two doses of medicine recoveries from illness.Ten Polynary money.It was treated 7 days, more than 6,000 yuan to county town within the same time another child 3 years old.
Arriving disease treatment afterwards is frequently utilized for hand-foot-and-mouth disease, curative for effect.
We are now widely used for infectiousness period, reduce the infection of disease, and effectively sick child is virgin for treatment, reduces children Disease pain.
When facing disease treatment dosage can be added and subtracted according to the weight of 2-8 years old children of child age.If young people has this sick energy It increases to measure to boil medicine and drink.
The present invention faces disease treatment now and is widely applied.
Above-mentioned case physical recovery normal health after taking drug of the present invention is because this drug has played its effect.
The above, only presently preferred embodiments of the present invention, not to the present invention make in any form with substantial limit System, all those skilled in the art, without departing from the scope of the present invention, when using disclosed above skill Art content, and the equivalent variations for a little variation, modification and evolution made, are equivalent embodiment of the invention;Meanwhile it is all according to According to substantial technological of the invention to the variation, modification and evolution of any equivalent variations made by upper embodiment, this hair is still fallen within In the range of bright technical solution.

Claims (6)

1. a kind of Chinese medicine composition for treating hand-foot-and-mouth disease.It is characterized in that, the Chinese medicine composition has the original of following weight parts Expect that medicine forms: 10-15 parts of oriental wormwood, 8-10 parts of chrysanthemum, 8-10 parts of folium isatidis, 10-15 parts of Radix Isatidis, 8-10 parts of wrinkled giant hyssop, lophatherum gracile 8-10 parts, 8-10 parts of rhizoma atractylodis, 6-8 parts of lotus leaf, 6-8 parts of the root of Dahurain angelica, 6-8 parts of honeysuckle flower, 3-6 parts of Radix Glycyrrhizae.
2. according to Chinese medicine composition described in claim 2:1 it is characterized in that the parts by weight of each bulk pharmaceutical chemicals are as follows: oriental wormwood 15 Part, 10 parts of chrysanthemum, 10 parts of folium isatidis, 10 parts of Radix Isatidis, 15 parts of wrinkled giant hyssop, 10 parts of lophatherum gracile, 10 parts of rhizoma atractylodis, 10 parts of lotus leaf, the root of Dahurain angelica 10 parts, 10 parts of honeysuckle flower, 6 parts of Radix Glycyrrhizae.
3. the Chinese medicine composition according to the 1 of claim and 2 it is characterized in that each bulk pharmaceutical chemicals parts by weight are as follows: oriental wormwood 8-12 parts, 8-12 parts of chrysanthemum, 8-12 parts, 8-12 parts of folium isatidis, 10-12 parts of Radix Isatidis, 8-12 parts of wrinkled giant hyssop, 8-12 parts of lophatherum gracile, 8-12 parts of rhizoma atractylodis, 8-12 parts of lotus leaf, 8-12 parts of the root of Dahurain angelica, 8-12 parts of honeysuckle flower, 3-7 parts of Radix Glycyrrhizae.
4. a kind of Chinese medical extract for treating hand-foot-and-mouth disease it is characterized by: the Chinese medical extract it is characterized by: in described The preparation of medicament extract Chinese medicine composition as described in claim 1-3 any claim.
5. the preparation method of Chinese medical extract described in claim 4 is it is characterized by: the preparation method is by the Chinese medicine Component decocting.Boiled with high heat with cold water soak 30 minutes, mild fire is 15 minutes pan-fried slowly, and primary half bowl, three times per day, one day one Agent (child's decrement).
6. the dosage form of Chinese medical extract preparation as claimed in claim 4 is it is characterized by: it is mentioned by Chinese medicine as claimed in claim 4 The dosage form of object preparation is taken it is characterized by: it is by Chinese medical extract as claimed in claim 4 and pharmaceutically acceptable carrier group At the dosage form is selected to oral solution water decoction, particle electuary, the water-bindered pill.
CN201910115494.0A 2019-02-15 2019-02-15 A kind of Chinese medicine composition for treating hand-foot-and-mouth disease, Chinese medical extract and preparation method thereof and dosage form Pending CN110123960A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103007085A (en) * 2012-12-31 2013-04-03 张明 Traditional Chinese medicine composition for treating hand-foot-and-mouth diseases
CN104758773A (en) * 2015-04-03 2015-07-08 王建芳 Traditional Chinese medicine preparation for treating hand-foot-and-mouth disease
CN105998402A (en) * 2016-06-20 2016-10-12 刘同祥 Pharmaceutical preparation for treating hand-foot-mouth disease and application of pharmaceutical preparation
CN107982327A (en) * 2017-12-11 2018-05-04 高金水 A kind of Chinese medicine composition for treating hand-foot-and-mouth disease and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103007085A (en) * 2012-12-31 2013-04-03 张明 Traditional Chinese medicine composition for treating hand-foot-and-mouth diseases
CN104758773A (en) * 2015-04-03 2015-07-08 王建芳 Traditional Chinese medicine preparation for treating hand-foot-and-mouth disease
CN105998402A (en) * 2016-06-20 2016-10-12 刘同祥 Pharmaceutical preparation for treating hand-foot-mouth disease and application of pharmaceutical preparation
CN107982327A (en) * 2017-12-11 2018-05-04 高金水 A kind of Chinese medicine composition for treating hand-foot-and-mouth disease and preparation method thereof

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
刘咏等: "清热解毒祛湿法防治儿童手足口病效果观察", 《光明中医》 *
宋立辉等: "149例手足口病患者的居家隔离治疗与预防分析", 《吉林医学》 *
徐珍: "手足口病辨证施护", 《中国实用医药》 *
李晓东等: "金银汤治疗手足口病115例疗效观察", 《中国现代药物应用》 *
郭相君等: "中医药治疗手足口腔病13例", 《吉林中医药》 *

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