CN101745081A - Compound cattail pollen for viral hepatitis - Google Patents

Abstract

The invention relates to the field of pharmaceutical formulation, in particular to compound cattail pollen for viral hepatitis, which is characterized by comprising the following raw material by weight percentage: 10 to 13 percent of dandelion, 9 to 12 percent of baikal skullcap root, 9 to 12 percent of isatis root, 5 to 7 percent of dyer woad leaf, 6 to 10 percent of oriental wormwood, 5 to 8 percent of gardenia, 3 to 5 percent of rhubarb, 3 to 5 percent of talcum, 5 to 7 percent of spora lygodii, 3 to 6 percent of red paeony root, 3 to 6 percent of nutgrass galingale rhizome, 3 to 6 percent of rhizome corydalis, 3 to 5 percent of radix bupleuri, 2 to 4 percent of Chinese angelica, 3 to 5 percent of bamboo shavings, 3 to 5 percent of bighead atractylodes rhizome and 3 to 6 percent of radix curcumae. The invention has low cost, has high curative effect for viral hepatitis, has no toxic side effect, can eliminate the clinical symptoms sign of the viral hepatitis and recover liver function, and is suitable for different types of viral hepatitis.

Description

The compound cattail pollen that is used for viral hepatitis

Technical field

The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of compound cattail pollen that is used for viral hepatitis.

Background technology

As everyone knows, viral hepatitis is caused by multiple hepatitis virus, based on one group of general infectious disease of liver injury.At present first, second, third, fourth, hepatitis E virus arranged by what nosetiology was clearly classified.Various viral hepatitis clinical manifestation is similar, and based on tired, inappetence, detest oil, abnormal liver function, jaundice appears in some cases.First type and penta type mainly show as actute infection, propagate through fecal-oral route; Second, third, fourth type are chronic infection more, and the minority case can develop into liver cirrhosis or hepatocarcinoma, mainly propagate through parenteral approach such as blood, body fluid.Treat viral hepatitis clinically according to different cause of diseases, different Clinical types and histology's infringement are treated with a certain discrimination, and the Therapeutic Principle of various hepatitis is all with competent rest, nutrition is main, be aided with suitable medicine, avoid drinking, the medicine of overwork and use infringement liver.To the clinical no specially good effect of the Drug therapy of hepatitis, medicines such as useful antiviral, anti-hepatic fibrosis and immunomodulating, not only financial burden is heavy, and therapeutic effect becomes clinical difficult point uncertainly.

Summary of the invention

Purpose of the present invention is exactly in order to overcome above-mentioned existing technical deficiency, a kind of compound cattail pollen that is used for viral hepatitis is provided, cost is low, treatment viral hepatitis curative effect height, have no side effect, have and eliminate viral hepatitis clinical symptoms sign, recover liver function, is applicable to various viral hepatitis.

The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of compound cattail pollen that is used for viral hepatitis, adopt Herba Taraxaci, Radix Scutellariae, Radix Isatidis, Folium Isatidis, Herba Artemisiae Scopariae, Fructus Gardeniae, Radix Et Rhizoma Rhei, Talcum, Spora Lygodii, Radix Paeoniae Rubra, Rhizoma Cyperi, Rhizoma Corydalis, Radix Bupleuri, Radix Angelicae Sinensis, Caulis Bambusae In Taenia, the Rhizoma Atractylodis Macrocephalae, Radix Curcumae is that feedstock production forms, make in order to the below method: earlier with the Spora Lygodii bundle, with Herba Taraxaci, Radix Scutellariae, Radix Isatidis, Folium Isatidis, Herba Artemisiae Scopariae, Fructus Gardeniae, Talcum, Radix Paeoniae Rubra, Rhizoma Cyperi, Rhizoma Corydalis, Radix Bupleuri, Radix Angelicae Sinensis, Caulis Bambusae In Taenia, the Rhizoma Atractylodis Macrocephalae, Radix Curcumae is soaked in water, remove slag after decocting and descend the Radix Et Rhizoma Rhei water filtrate of removing slag again in 1～2 minute of boiling before the filtrate again, the aseptic vial of packing into is interior standby, it is characterized in that the raw material composition is by weight percentage: Herba Taraxaci 10～13%, Radix Scutellariae 9～12%, Radix Isatidis 9～12%, Folium Isatidis 5～7%, Herba Artemisiae Scopariae 6～10%, Fructus Gardeniae 5～8%, Radix Et Rhizoma Rhei 3～5%, Talcum 3～5%, Spora Lygodii 5～7%, Radix Paeoniae Rubra 3～6%, Rhizoma Cyperi 3～6%, Rhizoma Corydalis 3～6%, Radix Bupleuri 3～5%, Radix Angelicae Sinensis 2～4%, Caulis Bambusae In Taenia 3～5%, the Rhizoma Atractylodis Macrocephalae 3～5%, Radix Curcumae 3～6%.

Beneficial effect of the present invention is, cost is low, treatment viral hepatitis curative effect height, have no side effect, have and eliminate viral hepatitis clinical symptoms sign, recover liver function, is applicable to various viral hepatitis.

The specific embodiment

The invention will be further described below in conjunction with embodiment:

Embodiment 1:

Adopting Herba Taraxaci, Radix Scutellariae, Radix Isatidis, Folium Isatidis, Herba Artemisiae Scopariae, Fructus Gardeniae, Radix Et Rhizoma Rhei, Talcum, Spora Lygodii, Radix Paeoniae Rubra, Rhizoma Cyperi, Rhizoma Corydalis, Radix Bupleuri, Radix Angelicae Sinensis, Caulis Bambusae In Taenia, the Rhizoma Atractylodis Macrocephalae, Radix Curcumae is that feedstock production forms.Its composition (weight %) is whenever taken medicine and is Herba Taraxaci 10.7, Radix Scutellariae 10.7, Radix Isatidis 10.7, Folium Isatidis 6.4, Herba Artemisiae Scopariae 6.4, Fructus Gardeniae 7.7, Radix Et Rhizoma Rhei 4.3, Talcum 4.3, Spora Lygodii 6.4, Radix Paeoniae Rubra 4.3, Rhizoma Cyperi 3.9, Rhizoma Corydalis 3.9, Radix Bupleuri 3.9, Radix Angelicae Sinensis 3.9, Caulis Bambusae In Taenia 3.9, the Rhizoma Atractylodis Macrocephalae 3.4, Radix Curcumae 5.2.Getting above-mentioned 17 flavor raw material total amounts is 233 grams.Earlier Spora Lygodii is wrapped separately with gauze, with Herba Taraxaci, Radix Scutellariae, Radix Isatidis, Folium Isatidis, Herba Artemisiae Scopariae, Fructus Gardeniae, Talcum, Radix Paeoniae Rubra, Rhizoma Cyperi, Rhizoma Corydalis, Radix Bupleuri, Radix Angelicae Sinensis, Caulis Bambusae In Taenia, the Rhizoma Atractylodis Macrocephalae, Radix Curcumae 16 flavor Chinese herbal medicine add water to 700～900ml, soaked 4～5 hours, boiling slow fire then with high heat decocts to about 100～120 minutes, remove slag and descend Radix Et Rhizoma Rhei to boil again 1～2 minute before the filtrate, remove slag again about filtrate 200ml, medicinal residues add water 300～400ml again and decoct 30 minutes, remove slag about filtrate 100ml, altogether 300ml left and right sides medicine juice, promptly make the compound cattail pollen of viral hepatitis.Pack in the aseptic vial, seal bottle cap is standby, and every day, 1 dose of branch 2 times was oral, and each (medicine) being taken before meal 150ml takes to the clinical symptoms sign and disappears, and it is normal that the liver function laboratory indexes recovers, and takes 10 days consolidating curative effect.

Principal agent Herba Taraxaci pharmacological action bacteriostatic test in of the present invention group: the Herba Taraxaci water decoction has stronger inhibitory action to staphylococcus aureus, and common pathogenic dermatophytes is had inhibitory action, and great choleretic effect and the effect of anti-human body pulmonary carcinoma are arranged.Nature and flavor are sweet, bitter, cold, function with heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation is used for hepatitis, upper respiratory tract infection, acute tonsillitis, pharyngolaryngitis, eye conjunctivitis, mumps, acute mastitis, gastroenteritis, dysentery, cholecystitis, acute appendicitis, urinary system infection, pelvic inflammatory disease, carbuncle furuncle furuncle etc.Radix Astragali bacteriostatic test: decoct has inhibitory action to alpha streptococcus, streptococcus pneumoniae, meningococcus, staphylococcus aureus, diphtheria corynebacterium, tubercule bacillus, vibrio cholera, dysentery bacterium and Candida albicans.Astragalus decoction has inhibitory action to strains of influenza viruses.White mice to viral infection is effective.Analgesic, calm, blood pressure lowering, diuresis, hepatoprotective effect are arranged, can increase dog, lapin bile excretion, the liver that white mice is caused because of carbon tetrachloride is poisoned Detoxication is arranged.The growth of the ameba of inhibition is arranged, killing action is arranged colluding Leptospiral.Nature and flavor hardship, cold.Have heat clearing and damp drying, detoxifcation, hemostasis, antiabortive function.Treating acute and chronic hepatitis, calentura fever, flu, conjunctival congestion and swelling pain, hematemesis and epistaxis, cough due to lung-heat, jaundice due to damp-heat, hypertension, headache, enteritis, dysentery, carbuncle furuncle infections, prevention scarlet fever, burn and scald etc.The Radix Isatidis bacteriostatic test: Isatis indigotica Fort. has inhibitory action to cold virus, to multiple viral infection good effect; Bacillus subtilis, escherichia coli, Bacillus typhi, Salmonella paratyphi, dysentery bacterium, bacillus enteritidis etc. are all had inhibitory action, and 1: 100 above dilution factor has the effect of the leptospira of killing.The nature and flavor bitter cold has the effect of heat-clearing and toxic substances removing, removing heat from blood.Be used for the treatment of acute infectious hepatitis, influenza, parotitis, encephalitis B, cerebrospinal meningitis, laryngopharynx swelling and pain etc.The Folium Isatidis bacteriostatic test: water decoction has strong inhibitory action to staphylococcus aureus, Staphylococcus albus, alpha streptococcus, meningococcus.Streptococcus pneumoniae, hemophilus influenza and dysentery bacterium also there is inhibitory action.Dilution factor is killed leptospiral effect more than 1: 100.Jaundice hemorrhage group Walden type, nanukayami type also there are killing action, are significantly increased the bile secretion effect, acute formaldehyde arthritis is had significantly antiinflammatory action.The nature and flavor bitter cold, heat-clearing and toxic substances removing, removing heat from blood function cure mainly epidemic encephalitis type B, flu, parotitis, upper respiratory tract infection, pneumonia, acute hepatitis, calentura and send out class, erysipelas, furuncle swelling toxin, venom etc.The Herba Artemisiae Scopariae water decoction has the effect of the bile secretion of promotion, when increasing bile secretion, has also increased cholic acid and bilirubinic output in the bile.To the hepatic injury that the rat carbon tetrachloride causes, the effect that increases bile secretion is arranged equally also.Tangible refrigeration function is arranged.Hepatitis virus is had inhibitory action, and the liver parenchymatous disease is decreased the improvement effect, and the blood pressure lowering antiasthmatic effect is arranged.Nature and flavor hardship, suffering, be slightly cold, have clearing away heat-damp and promoting diuresis, promoting the function of the gallbladder to alleviate jaundice function.Cure mainly icterohepatitis, cholecystitis.Fructus Gardeniae zoopery proof has obvious choleretic effect, and proof has the formation that suppresses blood mesobilirubin.Obvious calmness, blood pressure lowering, convulsion, anastalsis are arranged.Water decoction can be killed leptospira, kills bilharzial adult, can be quickened the healing effect of soft tissue contusion.Nature and flavor hardship, cold has the function of eliminating fire and detoxication, clearing away heat-damp and promoting diuresis, cool the blood dissipate blood stasis.Cure mainly icteric infectious hepatitis, calentura fever, dysphoria and insomnia, true length toothache, aphtha of the mouth and tongue, epistaxis, haematemesis, eye conjunctivitis, sore swollen toxin, favism, hematuria, traumatic hemorrhage, bruise etc.Radix Et Rhizoma Rhei has astriction, promotes anastalsises such as blood coagulation.Can promote digestive juice secretions such as bile, function of gallbladder promoting, calculus and increase Digestion are arranged.Blood pressure lowering arranged, separate spasm, cholesterol reducing, diuresis.Golden Portugal bacterium, dysentery bacterium, Bacillus typhi, vibrio cholera, escherichia coli, bacillus pyocyaneus, staphylococcus and dermatophytes etc. all there is antibacterial action.Nature and flavor hardship, cold has that removing the relative excess heat, removing mass stagnate, the function of blood stasis expelling blood.Cure mainly acute infectious hepatitis, excess-heat constipation, food stagnation stagnation, stomachache, acute appendicitis, blood stasis amenorrhea, toothache, epistaxis, acute conjunctivitis, carbuncle skin infection etc.The Talcum nature and flavor are sweet, light, cold, return bladder, lung, stomach warp, have the function that inducing diuresis for treating stranguria syndrome, clearing away summer-heat, damp eliminating are held back skin ulcer.Be used for treatments such as pyretic stranguria, stranguria caused by urinary stone, the puckery pain of urine heat, the wet excessive thirst of administration, damp and hot watery diarrhea.The Spora Lygodii nature and flavor are sweet, salty, cold, return bladder, small intestine meridian.Have eliminating damp-heat, treating stranguria analgesic function.Be used for pyretic stranguria, sand Stranguria, stranguria caused by urinary stone, stranguria with blood, stranguria marked by chyluria, Urethra astringent pain etc.The Radix Paeoniae Rubra bacteriostatic test all has inhibitory action to dysentery bacterium, vibrio cholera, staphylococcus.The nature and flavor hardship, be slightly cold, return Liver Channel.Function with clearing away heat and cooling blood, eliminating stasis to stop pain is used for the temperature poison and sends out treatments such as class, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, WEIJIA stomachache, traumatic injury, carbuncle skin infection.Rhizoma Cyperi nature and flavor suffering, be slightly cold, little sweet, flat.Return liver, spleen, tri-jiao channel.Function with promoting QI circulation for relieving depression, menstruction regulating and pain relieving.Be used for stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, colic of cold type stomachache, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea etc.Rhizoma Corydalis nature and flavor suffering, hardship, temperature are returned spleen channel.Have invigorate blood circulation, promoting the circulation of QI, analgesic function.Be used for the breast side of body, epigastric pain, amenorrhea dysmenorrhea, strongly fragrant resistance in puerperal, treating swelling and pain by traumatic injury etc.Radix Bupleuri nature and flavor hardship, be slightly cold, return liver, gallbladder meridian.Function with reconciling superficies and interior, soothing the liver, yang invigorating.Be used for cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, uterine prolapse, proctoptosis etc.The Radix Angelicae Sinensis nature and flavor are sweet, hot, warm, return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the function of loosening bowel to relieve constipation.Be used for the little Huang of blood deficiency, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia dryness of the intestine constipation Feng Shi Paralysis pain, traumatic injury, treatments such as carbuncle furuncle infections.The Caulis Bambusae In Taenia nature and flavor are sweet to be slightly cold, and attaches to the lung and stomach meridians.Has removing heat-phlegm.The function that relieves restlessness and prevents vomiting.Be used for phlegm-heat cough, gallbladder length is held expectorant under the arm, dysphoria with smothery sensation vomiting, palpitation with fear insomnia, middle wind-phlegm fan, aphasia with stiff tongue, gastropyretic vomiting, pregnancy reactions, frequent fetal movement etc.Rhizoma Atractylodis Macrocephalae bitter but sweet flavor temperature is returned the taste warp.Have invigorating the spleen and benefiting QI, make wet diuretic, hidroschesis, antiabortive function, be used for that insufficiency of the spleen lack of appetite, abdominal distention are had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement etc.The Radix Curcumae nature and flavor are arduous cold, return liver, the heart, lung meridian.Function with regulating qi to disperse stagnation, heart fire-clearing upset-relieving, dampness removing jaundice eliminating.Be used for that amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, epilepsy are gone mad, jaundice dark coloured urine etc.17 flavor Chinese herbal medicine ingenious prescriptions, coordinative role mutually between medicine is enshrined and worship the specially good effect of viral hepatitis.

Embodiment 2:

Adopting Herba Taraxaci, Radix Scutellariae, Radix Isatidis, Folium Isatidis, Herba Artemisiae Scopariae, Fructus Gardeniae, Radix Et Rhizoma Rhei, Talcum, Spora Lygodii, Radix Paeoniae Rubra, Rhizoma Cyperi, Rhizoma Corydalis, Radix Bupleuri, Radix Angelicae Sinensis, Caulis Bambusae In Taenia, the Rhizoma Atractylodis Macrocephalae, Radix Curcumae is that feedstock production forms.Its component (weight %) is whenever taken medicine and is Herba Taraxaci 11.1, Radix Scutellariae 10.9, Radix Isatidis 11.05, Folium Isatidis 6.45, Herba Artemisiae Scopariae 7.2, Fructus Gardeniae 6.8, Radix Et Rhizoma Rhei 4.6, Talcum 4.1, Spora Lygodii 6.7, Radix Paeoniae Rubra 4.5, Rhizoma Cyperi 4.3, Rhizoma Corydalis 4.2, Radix Bupleuri 3.5, Radix Angelicae Sinensis 3.1, Caulis Bambusae In Taenia 3.5, the Rhizoma Atractylodis Macrocephalae 3.2, Radix Curcumae 4.8.Getting above-mentioned 17 flavor raw material total amounts is 233 grams.Earlier Spora Lygodii is wrapped separately with gauze, with Herba Taraxaci, Radix Scutellariae, Radix Isatidis, Folium Isatidis, Herba Artemisiae Scopariae, Fructus Gardeniae, Talcum, Radix Paeoniae Rubra, Rhizoma Cyperi, Rhizoma Corydalis, Radix Bupleuri, Radix Angelicae Sinensis, Caulis Bambusae In Taenia, the Rhizoma Atractylodis Macrocephalae, Radix Curcumae 16 flavor Chinese herbal medicine add water to 700～900ml, soaked 4～5 hours, boiling slow fire then with high heat decocts to about 100～200 minutes, the preceding infra Radix Et Rhizoma Rhei of the filtrate of removing slag boiled 1～2 minute, remove slag again about filtrate 200ml, medicinal residues add water 300～400ml again and decoct about 30 minutes, remove slag about filtrate 100ml, altogether 300ml left and right sides medicine juice, promptly make the compound cattail pollen of viral hepatitis.Pack in the aseptic vial, seal bottle cap is standby.Every day, 1 dose of branch 2 times was oral, took to clinical symptoms sign disappearance liver function laboratory indexes about each (medicine) being taken before meal 150ml and recovered normal, took 10 days consolidating curative effect.

But each raw material of the present invention also blended embodiment of the listed ratio of according to the form below (percentage by weight) is realized.Its processing technique is identical with embodiment 1.

Embodiment	Herba Taraxaci	Radix Scutellariae	Radix Isatidis	Folium Isatidis	Because of old	Fructus Gardeniae	Radix Et Rhizoma Rhei	Talcum	Spora Lygodii	Radix Paeoniae Rubra	Rhizoma Cyperi	Rhizoma Corydalis	Radix Bupleuri	Radix Angelicae Sinensis	Caulis Bambusae In Taenia	The Rhizoma Atractylodis Macrocephalae	Radix Curcumae
																		??3	??10	??12	??9	??7	??6	??8	??3	??5	??5	??6	??3	??6	??3	??4	??5	??5	??3
??4	??13	??9	??12	??5	??10	??5	??5	??3	??7	??3	??6	??3	??5	??2	??3	??3	??6
																		??5	??12	??10	??10	??7	??8	??7	??4	??4	??6	??4	??4	??5	??4	??3	??4	??4	??4
??6	??11	??11	??11	??5	??7	??7	??3	??5	??7	??3	??5	??4	??3	??4	??5	??3	??6

Below in conjunction with my institute, promptly the clinical preliminary test that carries out of Shandong Province Wendeng Central Hospital, Weihai City is done further, is described in detail the present invention:

1, case is selected: this organizes 60 examples, and age 9-43 year, all cases all are the different viral hepatitis of degree.

2, Therapeutic Method: the raw material total amount of whenever taking medicine 233 grams, earlier Spora Lygodii is wrapped separately with gauze, with Herba Taraxaci, Radix Scutellariae, Radix Isatidis, Folium Isatidis, Artemisia anethoicles Mattf, Fructus Gardeniae, Talcum, Radix Paeoniae Rubra, Rhizoma Cyperi, Rhizoma Corydalis, Radix Bupleuri, Radix Angelicae Sinensis, Caulis Bambusae In Taenia, the Rhizoma Atractylodis Macrocephalae, Radix Curcumae 16 flavor Chinese herbal medicine add water to 700～900ml, soaked 4～5 hours, boiling slow fire then with high heat decocts to about 100～200 minutes, the preceding infra Radix Et Rhizoma Rhei of the filtrate of removing slag boiled 1～2 minute, remove slag again about filtrate 200ml, medicinal residues add water 300～400ml again and decoct about 30 minutes, remove slag about filtrate 100ml, altogether 300ml left and right sides medicine juice, promptly make the compound cattail pollen of viral hepatitis.Pack in the aseptic vial, seal bottle cap is standby, and every day, 1 dose of branch 2 times was oral, about each (medicine) being taken before meal 150ml, takes three months, consolidates curative effect again and takes 10 days.

3, therapeutic effect: use compound cattail pollen of the present invention to treat 60 examples altogether, effective 57 examples of result, invalid 3 examples, effective percentage is 95%, inefficiency is 5%.

Claims (1)

1. compound cattail pollen that is used for viral hepatitis, adopt Herba Taraxaci, Radix Scutellariae, Radix Isatidis, Folium Isatidis, Herba Artemisiae Scopariae, Fructus Gardeniae, Radix Et Rhizoma Rhei, Talcum, Spora Lygodii, Radix Paeoniae Rubra, Rhizoma Cyperi, Rhizoma Corydalis, Radix Bupleuri, Radix Angelicae Sinensis, Caulis Bambusae In Taenia, the Rhizoma Atractylodis Macrocephalae, Radix Curcumae is that feedstock production forms, make in order to the below method: earlier with the Spora Lygodii bundle, with Herba Taraxaci, Radix Scutellariae, Radix Isatidis, Folium Isatidis, Herba Artemisiae Scopariae, Fructus Gardeniae, Talcum, Radix Paeoniae Rubra, Rhizoma Cyperi, Rhizoma Corydalis, Radix Bupleuri, Radix Angelicae Sinensis, Caulis Bambusae In Taenia, the Rhizoma Atractylodis Macrocephalae, Radix Curcumae is soaked in water, remove slag after decocting and descend the Radix Et Rhizoma Rhei water filtrate of removing slag again in 1～2 minute of boiling before the filtrate again, the aseptic vial of packing into is interior standby, it is characterized in that the raw material composition is by weight percentage: Herba Taraxaci 10～13%, Radix Scutellariae 9～12%, Radix Isatidis 9～12%, Folium Isatidis 5～7%, Herba Artemisiae Scopariae 6～10%, Fructus Gardeniae 5～8%, Radix Et Rhizoma Rhei 3～5%, Talcum 3～5%, Spora Lygodii 5～7%, Radix Paeoniae Rubra 3～6%, Rhizoma Cyperi 3～6%, Rhizoma Corydalis 3～6%, Radix Bupleuri 3～5%, Radix Angelicae Sinensis 2～4%, Caulis Bambusae In Taenia 3～5%, the Rhizoma Atractylodis Macrocephalae 3～5%, Radix Curcumae 3～6%.