CN103505688B - Traditional Chinese medicine for treating liver-gallbladder damp-heat syndrome type oral ulcer - Google Patents
Traditional Chinese medicine for treating liver-gallbladder damp-heat syndrome type oral ulcer Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine for treating liver-gallbladder damp-heat syndrome type oral ulcer. The traditional Chinese medicine is characterized in that the traditional Chinese medicine is made from the following medicinal materials in parts by weight: gentiana scabra 10, paeonia suffruticosa bark 10, gardenia jasminoides fruit 10, scutellaria 10, radix rehmanniae 24, radix bupleuri 10, scrophularia ningpoensis 12, asiatic plantain seed 10, coptis chinensis 10, fructus amomi 10, ophiopogon japonicus 15, lophantherum gracile 6, glycyrrhiza uralensis 6, paeonia lactiflora pallas 20, anemarrhena asphodeloides 10, scutellaria barbata 15, and hedyotis diffusa 15. The traditional Chinese medicine disclosed in the invention has the effects of removing dampness and heat by diuresis, removing heat from the liver and smoothing the gallbladder. Owing to the adoption of appropriate medicinal materials and proportion thereof, interaction among the medicinal materials and synergistic action, the prepared traditional Chinese medicine can effectively treat the liver-gallbladder damp-heat syndrome type oral ulcer. For over three years, the clinical trial in 50 cases of oral ulcer patients suffering from the liver-gallbladder damp-heat syndrome type oral ulcer shows that the effectiveness rate reaches 84%.
Description
Technical field
thisinvention relates to a kind of Chinese medicine, particularly a kind of Chinese medicine being used for the treatment of liver-gallbladder damp-heat syndrome type oral ulcer.
Background technology
Dampness-heat in the liver and gallbladder refers to that damp and hot heresy pents up the disease of liver and gall.Many heresies damp and hot by diseases caused by exogenous pathogenic factor, or endogenous dampness, caused by strongly fragrant heat-transformation of a specified duration.Erosion of the oral mucosa disease is many because of retention of damp-heat in the interior, and caused by upper steaming oral cavity, in flakes rotten to the corn with oral cavity sarolemma, the smelly dirty grade of implication is the skin infection class disease of main manifestations.Liver-gallbladder damp-heat syndrome type oral ulcer is then because dampness-heat in the liver and gallbladder rises to oral cavity, makes caused by the sarolemma erosion of oral cavity.At present, treatment liver-gallbladder damp-heat syndrome type oral ulcer generally adopts treatment by Chinese herbs, although most of Chinese patent medicine has certain curative effect, effect is unsatisfactory.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of liver-gallbladder damp-heat syndrome type oral ulcer, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing liver-gallbladder damp-heat syndrome type oral ulcer.
For achieving the above object, the present invention by the following technical solutions:
A Chinese medicine for treatment liver-gallbladder damp-heat syndrome type oral ulcer, is characterized in that being prepared from by the medical material of following weight proportion:
Radix Gentianae 10 parts, Cortex Moutan 10 parts, Fructus Gardeniae 10 parts, Radix Scutellariae 10 parts, Radix Rehmanniae 24 parts, Radix Bupleuri 10 parts, Radix Scrophulariae 12 parts, Semen Plantaginis 10 parts, Rhizoma Coptidis 10 parts, Fructus Amomi 10 parts, Radix Ophiopogonis 15 parts, Herba Lophatheri 6 parts, 6 parts, Radix Glycyrrhizae, the Radix Paeoniae Alba 20 parts, the Rhizoma Anemarrhenae 10 parts, Herba Scutellariae Barbatae 15 parts, Herba Hedyotidis Diffusae 15 parts.
The source of the medical material adopted in formula of the present invention and function cure mainly as follows:
The root and rhizome that Radix Gentianae [source] is gentianaceae plant Radix Gentianae or G. triflora.[nature and flavor] are bitter, cold.[return through] enters liver, gallbladder meridian.[function cures mainly] eliminating pathogen in the liver gallbladder excess-fire, except damp-heat in lower-JIAO.Treating the liver is through intenseness of heat, and infantile convulsion is manic, encephalitis B, and headache, conjunctival congestion, pharyngalgia, jaundice, hematodiarrhoea, carbuncle skin infection, scrotum swells and ache, pudendum pruritus due to damp pathogen.For damp and hot yellow cellulitis, swelling of the vulva pudendal pruritus, leukorrhagia, eczema pruritus, deafness, hypochondriac pain, bitter taste, convulsion with spasms.
Cortex Moutan [source] this product is the dry root bark of ranunculaceae peony Paeonia suffruticosa Andr..[nature and flavor] are bitter, pungent, are slightly cold.[return through] GUIXIN, liver, kidney channel.[function cures mainly] clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.For maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters the pain of injury.
Fructus Gardeniae [source] this product is the dry mature fruit of Maguireothamnus speciosus Fructus Gardeniae Gardenia jasminoides Ellis, and its root also can be used as medicine.[nature and flavor] are bitter, cold.[return through] GUIXIN, lung, tri-jiao channel.[function cures mainly] fruit: pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Vexed for calentura, jaundice dark coloured urine, blood strangury and dry pain, heat in blood tells nosebleed, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles; External treatment bruise pain.
Radix Scutellariae [source] this product is the dry root of labiate Radix Scutellariae Scutellaria baicalensis Georgi.[nature and flavor] are bitter, cold.[return through] returns lung, gallbladder, spleen, large intestine, small intestine meridian.[function cures mainly] heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tells nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
Radix Rehmanniae [source] is for celebrating the root of Radix Rehmanniae in dicotyledon medicine scrophulariaceae rehmannia glutinosa plant or bosom.[nature and flavor] sweetness and bitterness, cool.[return through] enters the heart, liver, kidney channel.[effect] clearing away heat and promoting production of body fluid YIN nourishing, nourishes blood.Control fever due to yin deficiency, quench one's thirst, spit blood, epistaxis, metrorrhagia, menoxenia, frequent fetal movement, the moon hinders constipation.
Radix Bupleuri [source] this product is the dry root of umbelliferae bupleurum Bupleurum chinense DC. or Radix Bupeuri Scorzonerfolii. Bupleurum scorzonerifolium Willd..[nature and flavor] are bitter, are slightly cold.[return through] returns liver, gallbladder meridian.[function cures mainly] reconciling superficies and interior, soothing the liver, yang invigorating.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, proctoptosis.
Radix Scrophulariae [source] this product is the dry root of goatweed Radix Scrophulariae Scrophularia ningpoensis Hemsl..[nature and flavor] are sweet, bitter, salty, are slightly cold.[return through] returns lung, stomach, kidney channel.[function cures mainly] removing heat from blood YIN nourishing, eliminating fire and detoxication.For consumption of YIN caused by febrile disease, crimson tongue excessive thirst, maculae caused by violent heat pathogen, constipation is hindered in Tianjin, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus.
Semen Plantaginis [source] this product is the dry mature seed of Plantaginaceae plant Herba Plantaginis Plantago asiatica L. or Plantago depressa Willd Plantago depressa Willd..[nature and flavor] are sweet, are slightly cold.[return through] returns liver, kidney, lung, small intestine meridian.[function cures mainly] clearing away heat and promoting diuresis, eliminating dampness by diuresis is treating stranguria, improving eyesight, eliminates the phlegm.For edema distension, the puckery pain of pyretic stranguria, diarrhea due to summer heat and dampness, conjunctival congestion and swelling pain, phlegm-heat cough.
Rhizoma Coptidis [source] this product is the dry rhizome of ranunculaceae plant Rhizoma Coptidis Coptis chinensis Franch., Coptis deltoidea C.Y.Cheng et Hsiao Coptis deltoidea C. Y. Cheng et Hsiao or Coptis Teeta Wall Coptis teeta Wall..[nature and flavor] are bitter, cold.[return through] GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.[function cures mainly] heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle.
Fructus Amomi [source] this product is the dry mature fruit of zingiberaceous plant Fructus Amomi Amomum villosum Lour., green shell sand Amomum villosum Lour. var. xanthioides T. L. Wu et Senjen or SEMEN AMOMI LONGILIGULA Amomum longiligulare T. L. Wu.[nature and flavor] are pungent, temperature.[return through] returns spleen, stomach, kidney channel.[function cures mainly] removing dampness is whetted the appetite, warming spleen and stopping diarrha, regulates the flow of vital energy antiabortive.For turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass is not hungry, Deficiency and coldness of spleen and stomach, and vomiting is had loose bowels, pregnancy reactions, frequent fetal movement.
The tuber that Radix Ophiopogonis [source] is liliaceous plant dwarf lilyturf.[nature and flavor] sweet micro-hardship, cold.[return through] enters lung, stomach, heart channel.[function cures mainly] nourishing YIN and moistening the lung, clear away heart-fire relieving restlessness, reinforcing stomach reg fluid.Control dryness of the lung dry cough, spit blood, spitting of blood, consumptive lung disease, lung abscess, asthenia dysphoria with smothery sensation, quenches one's thirst, and calentura Tianjin is hindered, dry mouth and throat, constipation.
Herba Lophatheri [source] this product is the dry stem and leaf of grass Herba Lophatheri Lophatherum gracile Brongn..[nature and flavor] are sweet, light, cold.[return through] GUIXIN, stomach, small intestine meridian.[function cures mainly] clearing heat and relieving fidgetness, diuresis.For calentura excessive thirst, hot urination drenches pain, aphtha of the mouth and tongue.
Radix Glycyrrhizae [source] this product is the dry root of glycyrrhizic legume Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L. Glycyrrhiza glabra L..[nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
The Radix Paeoniae Alba [source] this product is the dry root of ranunculaceae plant Radix Paeoniae Paeonia lactiflora Pall..[nature and flavor] are bitter, sour, are slightly cold.[return through] returns liver, spleen channel.The pain relieving of [function cures mainly] suppressing the hyperactive liver, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
The Rhizoma Anemarrhenae [source] this product is the dry rhizome of liliaceous plant Rhizoma Anemarrhenae Anemarrhena asphodeloides Bunge..[nature and flavor] are bitter, sweet, cold.[return through] returns lung, stomach, kidney channel.[function cures mainly] clearing away heat-fire, promotes the production of body fluid and moisturizes.For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.
Herba Scutellariae Barbatae [source] this product is the dry herb of labiate Herba Scutellariae Barbatae Scutellaria barbata Don [S. rivularis Wall].[nature and flavor] are pungent, bitter, cold.[return through] returns lung, liver, kidney channel.
[function cures mainly] heat-clearing and toxic substances removing, blood stasis dispelling diuresis.For furuncle swelling toxin, laryngopharynx swelling and pain, venom, falls and flutters the pain of injury, edema, jaundice.
Herba Hedyotidis Diffusae [source] this product is the herb of Rubiaceae plants of Hedyotis Herba Hedyotidis Diffusae Hedyotis diffusa Willd. [Oldenlandia diffusa (Willd.) Roxb.].[nature and flavor] are sweet, light, cool.[return through] enters stomach, large intestine, small intestine meridian.[function cures mainly] heat-clearing and toxic substances removing, inducing diuresis to remove edema, promoting blood circulation and stopping pain.For acute appendicitis (appendicitis), furuncle toxic swelling, jaundice due to damp-heat, the diseases such as dysuria; Furuncle carbuncle is controlled in external, venom.
Dampness-heat in the liver and gallbladder mostly is the damp and hot heresy of impression, or delicious food of being addicted to drink, and change raw damp and hot, or transporting and transforming function of the spleen and stomach is not normal, endogenous damp formation, damp-stagnancy heat-transformation, caused by damp-heat accumulation liver and gall.Damp and hotly steam mutually, accumulate in liver and gall, suffocating of liver and gall is not normal, courage overflow and cause bitter taste, damp and hot upper steaming, inside accumulates in oral cavity, and makes oral cavity sarolemma in flakes rotten to the corn, accompany the smelly dirty symptom of implication simultaneously.The treatment of primary disease is in order to damp and clearing heat, and liver heat removing function of gallbladder promoting is main.The present invention adopts suitable medical material and proportioning thereof, cooperatively interacts between each medical material, synergism, made Chinese medicine effectively can treat liver-gallbladder damp-heat syndrome type oral ulcer, more than 3 years, by showing the use of 50 routine liver-gallbladder damp-heat syndrome type oral ulcer patients, effective percentage reaches 84%.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor have collected 72 example treatment liver-gallbladder damp-heat syndrome type oral ulcer out-patients altogether between in March ,-2012 in January, 2009, wherein, man 38 example, female, 34 examples, age 21-43 year, the state of an illness 1 month to 1 year.Be divided at random: treatment group 50 example, matched group 22 example.The data there was no significant differences such as two groups of ages, have comparability.
2, test method
The oral LONGDAN XIEGAN WAN of 2.1 matched group, takes to specifications.15 days courses for the treatment of.
The oral the present invention of 2.2 treatment group according to the obtained capsule of specific embodiment 1, early, middle and late each once, 15 days courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterions of therapeutical effect:
Recovery from illness: clinical symptoms all disappears, and test chamber inspection is normal.Take a turn for the better: clinical symptom relief, the state of an illness is controlled, experimental check improvement or normal.Invalid: clinical symptoms is without being clearly better or increasing the weight of.
3.2 treatment statistical results are in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Take a turn for the better | Invalid | Total effective rate (%) |
| Treatment group | 50 | 4 | 38 | 8 | 84% |
| Matched group | 22 | 1 | 10 | 11 | 50% |
As can be seen here, the medicine that the present invention obtains can safe and effective treatment liver-gallbladder damp-heat syndrome type oral ulcer.
Detailed description of the invention
In order to Comprehension and Implementation the present invention better, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take Radix Gentianae 10 grams, Cortex Moutan 10 grams, Fructus Gardeniae 10 grams, Radix Scutellariae 10 grams, Radix Rehmanniae 24 grams, Radix Bupleuri 10 grams, Radix Scrophulariae 12 grams, Semen Plantaginis 10 grams, Rhizoma Coptidis 10 grams, Fructus Amomi 10 grams, Radix Ophiopogonis 15 grams, Herba Lophatheri 6 grams, 6 grams, Radix Glycyrrhizae, the Radix Paeoniae Alba 20 grams, the Rhizoma Anemarrhenae 10 grams, Herba Scutellariae Barbatae 15 grams, Herba Hedyotidis Diffusae 15 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, the capsule of adult normal's 1 day consumption must be met.
Be used for the treatment of liver-gallbladder damp-heat syndrome type oral ulcer.Oral, every bu is taken for early, middle and late three times.
Specific embodiment 2
Take Radix Gentianae 10 grams, Cortex Moutan 10 grams, Fructus Gardeniae 10 grams, Radix Scutellariae 10 grams, Radix Rehmanniae 24 grams, Radix Bupleuri 10 grams, Radix Scrophulariae 12 grams, Semen Plantaginis 10 grams, Rhizoma Coptidis 10 grams, Fructus Amomi 10 grams, Radix Ophiopogonis 15 grams, Herba Lophatheri 6 grams, 6 grams, Radix Glycyrrhizae, the Radix Paeoniae Alba 20 grams, the Rhizoma Anemarrhenae 10 grams, Herba Scutellariae Barbatae 15 grams, Herba Hedyotidis Diffusae 15 grams, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's 1 day consumption.
Be used for the treatment of liver-gallbladder damp-heat syndrome type oral ulcer.Oral, every bu is taken for early, middle and late three times.
Specific embodiment 3
Take Radix Gentianae 10 grams, Cortex Moutan 10 grams, Fructus Gardeniae 10 grams, Radix Scutellariae 10 grams, Radix Rehmanniae 24 grams, Radix Bupleuri 10 grams, Radix Scrophulariae 12 grams, Semen Plantaginis 10 grams, Rhizoma Coptidis 10 grams, Fructus Amomi 10 grams, Radix Ophiopogonis 15 grams, Herba Lophatheri 6 grams, 6 grams, Radix Glycyrrhizae, the Radix Paeoniae Alba 20 grams, the Rhizoma Anemarrhenae 10 grams, Herba Scutellariae Barbatae 15 grams, Herba Hedyotidis Diffusae 15 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, granulate according to this area common process, packaging, must meet the granule of adult normal's 1 day consumption.
Be used for the treatment of liver-gallbladder damp-heat syndrome type oral ulcer.Oral, every bu is taken for early, middle and late three times.
Claims (1)
1. treat a Chinese medicine for liver-gallbladder damp-heat syndrome type oral ulcer, it is characterized in that being prepared from by the medical material of following weight proportion:
Radix Gentianae 10 parts, Cortex Moutan 10 parts, Fructus Gardeniae 10 parts, Radix Scutellariae 10 parts, Radix Rehmanniae 24 parts, Radix Bupleuri 10 parts, Radix Scrophulariae 12 parts, Semen Plantaginis 10 parts, Rhizoma Coptidis 10 parts, Fructus Amomi 10 parts, Radix Ophiopogonis 15 parts, Herba Lophatheri 6 parts, 6 parts, Radix Glycyrrhizae, the Radix Paeoniae Alba 20 parts, the Rhizoma Anemarrhenae 10 parts, Herba Scutellariae Barbatae 15 parts, Herba Hedyotidis Diffusae 15 parts.
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