CN103071119B - Traditional Chinese medicine for treating cholestatic jaundice - Google Patents
Traditional Chinese medicine for treating cholestatic jaundice Download PDFInfo
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a traditional Chinese medicine for treating cholestatic jaundices. The traditional Chinese medicine is prepared by the following medicines in part by weight: 12 parts of astragalus, 8 parts of cuscuta chinensis, 8 parts of eucommia ulmoides oliv, 10 parts of curcuma zedoary, 6 parts of artemisia anomala, 12 parts of radix asparagi, 10 parts of radix polygonati officinalis, 14 parts of coxtex moutan, 14 parts of rhizoma anemarrhenae, 12 parts of radix paeoniae alba, 10 parts of donkey-hide gelatin, 14 parts of Chinese yam, 14 parts of honeysuckle, 12 parts of selfheal, 10 parts of polygonum multiflorum, 8 parts of the seed of cowherb, 6 parts of salvia chinensis and 6 parts of Chinese blister beetle. Clinical experiments show that the traditional Chinese medicine for treating the cholestatic jaundices, provided by the invention, can safely and effectively treat the cholestatic jaundices.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine for the treatment of the yellow cellulitis of cholestasis.
Background technology
The yellow cellulitis of cholestasis, bile secretion is the critical function of liver, because various harmful factors cause bile secretion and excretion, obstacle occurs, and forms cholestegnosis, pathological changes person in liver is called intrahepatic cholestasis, in liver epigenesist, is called property cholestasis outside liver.Take obstructive jaundice and without biliary obstruction inside and outside macroscopic liver as its feature.For the yellow cellulitis of cholestasis, still lack at present the effective medicine of generally recognized as safe.
The present Research of the related medical material of Chinese medicine of the present invention is as follows:
The Radix Astragali [source] is the root of leguminous plant Radix Astagali or Radix Astragali.Remove fibrous root and root head, dry, section, raw using or processed with honey use.[function cures mainly] has enhancing human body immunity function, protects the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.
The seed of Semen Cuscutae [source] dicotyledon scammonia section plant Semen Cuscutae, southern Semen Cuscutae, cuscuta japonica Choisy etc.[function cures mainly] has the effect of the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, solid tire stopping leak.
The dry bark of the Cortex Eucommiae [source] the Eucommiaceae plant Cortex Eucommiae (Eucommia ulmoides Oliver) is Chinese famous and precious tonic herb.[function cures mainly] invigorating the liver and kidney, bone and muscle strengthening, blood pressure lowering, many effects such as antiabortive.
These product of Gecko [source] are flat lamellar, incidence and trunk minister 9～18cm, and incidence accounts for 1/3rd, and body is close by circle or the micro-glossiness thin squama of polygon, gas raw meat, taste is micro-salty.[function cures mainly] invigorating the lung and the kidney, helping inspiration to relieve asthma, supporing yang benefit essence.Treatment cough due to deficiency of the lung, suffers from a deficiency of the kidney and breathes heavily, and asthenia is breathed with cough.
Rhizoma Curcumae [source] Rhizoma Curcumae is perennial root draft.The dry rhizome of zingiberaceous plant Rhizoma Curcumae, Guangxi zedoary or RADIX CURCUMAE.[function cures mainly] circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving.For Dan abdominal mass mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain; Early cervical carcinoma.
The herb of Herba Artemisiae Anomalae [source] feverfew artemisia anomalas.[function cures mainly] hemostasis of curing the wound, removing blood stasis dysmenorrhea, promoting digestion and removing stagnation, the effect of the appetizing of being amusing.It can be used for acute icterohepatitis, toothache, chronic tracheitis, stomatitis, pharyngolaryngitis, tonsillitis, nephritis, malaria; Eye conjunctivitis is controlled in external, otitis media, skin infection, eczema, traumatic hemorrhage.
Radix Asparagi [source] liliaceous plant.Have another name called Radix Asparagi.Cold in nature, sweet in the mouth, micro-hardship.There is replenishing YIN and removing heat, the effect of lung moistening nourishing kidney.[function cures mainly] for controlling fever due to yin deficiency, cough haematemesis, lung abscess, laryngopharynx swelling and pain, quench one's thirst, the disease such as constipation.
Rhizoma Polygonati Odorati [source] is Liliaceae herbaceos perennial.Rhizome horizontal walk, meat yellow-white, the most fibrous roots of close life.Dry, or after steaming thoroughly, rub to translucent, dry, cut sheet or section use.[function cures mainly] nourishing YIN and moistening the lung; Nourishing the stomach to promote the production of body fluid.Cough caused by dryness; Chronic cough; The dry throat and mouth of the cloudy liquid consumption of calentura wound; Interior-heat is quenched one's thirst; Deficiency of YIN diseases caused by exogenous pathogenic factor; Dizzy dizzy; Muscle arteries and veins spasm and pain.
Cortex Moutan [source] is the root bark of Ranunculaceae Paeonia plant Paeonia suffruticosa, containing paeonol, and paeonolide, volatile oil and plant sterol etc.[function cures mainly] Cortex Moutan reduces blood pressure, eases pain, calm, antiinflammatory and refrigeration function; Various pathogens is had to stronger inhibitory action.It is cool in nature, bitter in the mouth, pungent, and function heat clearing away, removing heat from blood and blood, the clear stasis of blood, be applicable to thermal man's blood system, sends out speckle, frightened pain, haematemesis, carbuncle and ulcer, the diseases such as traumatic injury.
The Rhizoma Anemarrhenae [source] is the rhizome of the liliaceous plant Rhizoma Anemarrhenae, containing multiple Saponin and Saponin it, contain in addition two kinds of flavonoids and become Mengiferin etc.[function cures mainly] Rhizoma Anemarrhenae has obvious refrigeration function, and Epidemic Hemorrhagic Fever, epidemic encephalitis type B, pulmonary tuberculosis hectic fever all have obvious curative effects.It is cold in nature, sweet in the mouth, hardship, and function clearing away heat-fire, nourshing Yin and drynsessmoistening prescription, is applicable to lung-heat cough with asthma or cough due to yin deficiency, and dysphoria with smothery sensation is quenched one's thirst, hectic fever due to YIN-deficiency consumptive fever, dysuria, the diseases such as constipation due to dry stool.
The Radix Paeoniae Alba [source] is the root of dicotyledon medicine cohosh Radix Paeoniae (cultigen).The Peony Root of having planted 3～4 years, removes rhizome and fibrous root, cleans, and scrapes off rough bark, enters in boiling water and slightly boils, and Chinese herbaceous peony root is felt like jelly, and pulls out and dries.[function cures mainly] nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.Control the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.
Rhizoma Dioscoreae [source] herbaceos perennial, stem is overgrow, and is often with purple, and tuber is cylindrical, and leaf is to life, avette or oval, flower milky, dioecism.Starch-containing and the protein of tuber.[function cures mainly] spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, and leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.
Flos Lonicerae [source] Flos Lonicerae is the alabastrum of caprifoliaceae plant Radix Ophiopogonis, containing chlorogenic acid, and inositol, flavones ingredient etc.[function cures mainly] Flos Lonicerae has antiinflammatory and refrigeration function, and infected by influenza and various pathogens, skin pathomycete have inhibitory action, have reflected the heat-clearing toxin-expelling functions of Flos Lonicerae.It is cold in nature, sweet in the mouth, and function heat clearing away, removing toxic substances, is applicable to epidemic febrile disease heating, toxic-heat and blood stasis, the disease of the hyperactivity of toxic heat such as skin ulcer, carbuncle, furuncle and phyma.
Spica Prunellae [source] Spica Prunellae is flowers or the herb of labiate Spica Prunellae, includes triterpenoid saponin and glycoside unit oleanolic acid thereof, volatile oil and vitamin, potassium chloride etc.[function cures mainly] it is cold in nature, bitter in the mouth, pungent, and function clearing away liver-fire, Disperse hepatic depression, blood pressure lowering, is applicable to the conjunctival congestion and swelling pain due to flaming up of liver-fire, ophthalmalgia, photophobia is shed tears, headache, dizzy etc.; For the scrofula due to phlegm-fire pent-up, goiter etc.
Radix Polygoni Multiflori [source] is the perennial winding of Polygonaceae liana.Root is elongated, and end becomes loose tuber, and appearance bronzing is to crineous.Tuber, rattan and the leaf of plant all can hyoscine.[function cures mainly] removing toxic substances, loosening bowel to relieve constipation, eliminating carbuncle; Enrich and benefit essence and blood, black beard and hair, bone and muscle strengthening, invigorating the liver and kidney.Promote hemopoietic function, strengthen immunologic function.
The dry mature seed of Semen Vaccariae [source] dicotyledon Caryophyllaceae Caryophyllaceae Vaccaria segetalis.[function cures mainly] promoting the circulation of blood regulating menstruation, reducing swelling and alleviating pain, the lactogenesis of invigorating blood circulation, expedite the emergence of the thymus dredging of stimulating milk secretion, puerperal.Cure mainly: blood stasis amenorrhea, dysmenorrhea, difficult labour; Lack of lactation after delivery, acute mastitis swells and ache; Pyretic stranguria, stranguria with blood, stranguria caused by urinary stone.
Herba Salviae Chinensis [source] is the herb of labiate Salvia chinensis, taps herb florescence, using fresh herb or dry.[function cures mainly] blood circulation promoting and blood stasis dispelling; Clearing away heat-damp and promoting diuresis; Mass dissipating and swelling eliminating.Main menoxenia; Dysmenorrhea; Amenorrhea; Metrorrhagia, has blood in stool; Jaundice due to damp-heat; Hot toxic-heat and blood stasis; Drench pain; Leukorrhagia; Rheumatic ostalgia; Scrofula; Skin ulcer is swollen; Acute mastitis; Herpes zoster; Leprosy; Traumatic injury wound is swollen.
These product of Mylabris [source] are the dry body of Meloidae insecticide south mylabris phalerata (large speckle brassica rapa) or yellow black mylabris cichorii (eye speckle Yuan green grass or young crops).[function cures mainly] counteracting toxic substances phagedenoma; Removing blood stasis eliminating stagnation.Main carbuncle; Scrofula; Stubborn dermatitis; Amenorrhea; Lump in the abdomen; Cancerous protuberance.Yong Yu WEIJIA lump, stubborn dermatitis for many years, scrofula, wart, carbuncle is not steeped, the dead flesh of malignant boil.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of the yellow cellulitis of cholestasis, by selecting suitable medical material and proportioning thereof, reaches the object of the yellow cellulitis of safe and effective healing cholestasis.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for the treatment of the yellow cellulitis of cholestasis, it is characterized in that, by the medical material of following weight proportion, be prepared from: 12 parts of the Radixs Astragali, 8 parts of Semen Cuscutae, 8 parts of the Cortexs Eucommiae, 10 parts of Geckos, 6 parts of Rhizoma Curcumae, 6 parts of Herba Artemisiae Anomalaes, 12 parts of Radix Asparagi, 10 parts of Rhizoma Polygonati Odorati, 14 parts of Cortex Moutans, 14 parts of the Rhizoma Anemarrhenaes, 12 parts of the Radix Paeoniae Albas, 14 parts of Rhizoma Dioscoreaes, 14 parts of Flos Loniceraes, 12 parts of Spica Prunellaes, 10 parts of Radix Polygoni Multiflori, 8 parts of Semen Vaccariae, 6 parts of Herba Salviae Chinensiss, 6 parts of Mylabris.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
1, physical data
Inventor collects the out-patient of the yellow cellulitis of 85 routine cholestasis for 2009 altogether between year JIUYUE of November-2011, age 12-52 year, course of disease 0.5-7.Be divided at random: treatment group 60 examples, blank group 25 examples.The data there was no significant differences such as two groups of ages, the state of an illness, have comparability.
2, test method
The capsule that the oral the present invention of 2.1 treatment group makes according to specific embodiment 1, sooner or later respectively once.30 days courses for the treatment of.
2.2 blank group oral placebo capsules, sooner or later respectively once.30 days courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, and test chamber inspection is normal.Take a turn for the better: clinical symptom relief, the state of an illness is controlled, and lab testing improves or is normal.Invalid: clinical symptoms is without being clearly better or increasing the weight of.
3.2 treatment statistical results are in Table 1.
Table 1 liang group curative effect comparison
Visible, the medicine that the present invention makes can safe and effectively be controlled the yellow cellulitis of cholestasis.
The specific embodiment
In order to understand better and to implement the present invention, below in conjunction with specific embodiment, further illustrate the present invention.
Specific embodiment 1
Take: 12 grams of the Radixs Astragali, 8 grams of Semen Cuscutae, 8 grams of the Cortexs Eucommiae, 10 grams of Geckos, 6 grams of Rhizoma Curcumae, 6 grams of Herba Artemisiae Anomalaes, 12 grams of Radix Asparagi, 10 grams of Rhizoma Polygonati Odorati, 14 grams of Cortex Moutans, 14 grams of the Rhizoma Anemarrhenaes, 12 grams of the Radix Paeoniae Albas, 14 grams of Rhizoma Dioscoreaes, 14 grams of Flos Loniceraes, 12 grams of Spica Prunellaes, 10 grams of Radix Polygoni Multiflori, 8 grams of Semen Vaccariae, 6 grams of Herba Salviae Chinensiss, 6 grams of Mylabris, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, must meet the capsule of 1 day consumption of normal adult.
Be used for the treatment of the yellow cellulitis of cholestasis.Oral, every bu is taken for twice sooner or later.
Specific embodiment 2
Take: 12 grams of the Radixs Astragali, 8 grams of Semen Cuscutae, 8 grams of the Cortexs Eucommiae, 10 grams of Geckos, 6 grams of Rhizoma Curcumae, 6 grams of Herba Artemisiae Anomalaes, 12 grams of Radix Asparagi, 10 grams of Rhizoma Polygonati Odorati, 14 grams of Cortex Moutans, 14 grams of the Rhizoma Anemarrhenaes, 12 grams of the Radix Paeoniae Albas, 14 grams of Rhizoma Dioscoreaes, 14 grams of Flos Loniceraes, 12 grams of Spica Prunellaes, 10 grams of Radix Polygoni Multiflori, 8 grams of Semen Vaccariae, 6 grams of Herba Salviae Chinensiss, 6 grams of Mylabris, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, pulverize, must meet the powder of 1 day consumption of normal adult.
Be used for the treatment of the yellow cellulitis of cholestasis.Oral, every bu is taken for twice sooner or later.
Specific embodiment 3
Take: 12 grams of the Radixs Astragali, 8 grams of Semen Cuscutae, 8 grams of the Cortexs Eucommiae, 10 grams of Geckos, 6 grams of Rhizoma Curcumae, 6 grams of Herba Artemisiae Anomalaes, 12 grams of Radix Asparagi, 10 grams of Rhizoma Polygonati Odorati, 14 grams of Cortex Moutans, 14 grams of the Rhizoma Anemarrhenaes, 12 grams of the Radix Paeoniae Albas, 14 grams of Rhizoma Dioscoreaes, 14 grams of Flos Loniceraes, 12 grams of Spica Prunellaes, 10 grams of Radix Polygoni Multiflori, 8 grams of Semen Vaccariae, 6 grams of Herba Salviae Chinensiss, 6 grams of Mylabris, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, and according to this area common process, to granulate, packing, can make the granule that meets 1 day consumption of normal adult.
Be used for the treatment of the yellow cellulitis of cholestasis.Oral, every bu is taken for twice sooner or later.
Claims (1)
1. treat the Chinese medicine of the yellow cellulitis of cholestasis for one kind, it is characterized in that, by the medical material of following weight proportion, be prepared from: 12 parts of the Radixs Astragali, 8 parts of Semen Cuscutae, 8 parts of the Cortexs Eucommiae, 10 parts of Geckos, 6 parts of Rhizoma Curcumae, 6 parts of Herba Artemisiae Anomalaes, 12 parts of Radix Asparagi, 10 parts of Rhizoma Polygonati Odorati, 14 parts of Cortex Moutans, 14 parts of the Rhizoma Anemarrhenaes, 12 parts of the Radix Paeoniae Albas, 10 parts, Colla Corii Asini, 14 parts of Rhizoma Dioscoreaes, 14 parts of Flos Loniceraes, 12 parts of Spica Prunellaes, 10 parts of Radix Polygoni Multiflori, 8 parts of Semen Vaccariae, 6 parts of Herba Salviae Chinensiss, 6 parts of Mylabris.
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