CN103071027A - Traditional Chinese medicine for treating congenital pulmonary arterio-venous fistula - Google Patents
Traditional Chinese medicine for treating congenital pulmonary arterio-venous fistula Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine for treating congenital pulmonary arterio-venous fistula. The traditional Chinese medicine is prepared from the following medicines in part by weight: 6 parts of gynostemma pentaphyllum, 12 parts of poria cocos, 14 parts of polygonum multiflorum, 10 parts of fructus evodiae, 8 parts of gymnema sylvestre schult, 8 parts of chrysosplenium, 14 parts of astragalus, 12 parts of radix paeoniae alba, 12 parts of butterflybush flower, 12 parts of fresh rehmannia, 12 parts of honeysuckle, 14 parts of selfheal, 8 parts of coxtex moutan, 8 parts of rhizoma anemarrhenae, 14 parts of semen cassiae and 8 parts of cortex lycii radicis. Clinical experiments prove that the traditional Chinese medicine provided by the invention can safely and effectively treat the congenital pulmonary arterio-venous fistula.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine for the treatment of congenital pulmonary arteriovenous fistula.
Background technology
Congenital pulmonary arteriovenous fistula (congenital pulmonary arterio-venous fistula, PAVF) also claim arteriovenous aneurysm, be more common congenital developmental disorder, the blood capillary ramus anastomoticus enlarges between period of embryo's pulmonary circulation arteriovenous, forms unusual traffic between the lung arteriovenous.About 1/3 patient is the interior multiple focus of lung and belongs to the dominant inheritance.About 10% patient infantile period symptom appears and mostly number average symptom appears after growing up, also can be without any Symptoms, lopsided pathological changes is often aggravated with age growth, clinical symptoms finally occurs.Cardinal symptom shows as spitting of blood in various degree, tachypnea, cardiopalmus and chest pain.
Still lack at present the effective medicine of generally recognized as safe for congenital pulmonary arteriovenous fistula.
The present Research of the related medical material of Chinese medicine of the present invention is as follows:
Herb Gynostemmae Pentaphylli [source] perennial root plant, cold in nature, sweet in the mouth has QI invigorating, calms the nerves, the effect of blood pressure lowering, main effective ingredient is polysaccharide, flavonoid, saponins and microelement kind.[function cures mainly] promotes body fat class substance metabolism, nutrition human body cell, has simultaneously the detoxicating, relieving inflammation effect.
Poria [source] colonizes in the fungi plant on the pinaster root, and shape is as Rhizoma Dioscoreae esculentae, and its protozoa is the dry sclerotia of On Polyporaceae Poria, and multiparasitization is in the root of Pinus massoniana Lamb or Pinus densiflora.[function cures mainly] sweet in the mouth, light, property are flat, be used as medicine have promoting diuresis to eliminate damp pathogen, the function of strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Energy enhancing human body immunity function, pachyman has obvious antitumor and protects the liver dirty effect.
Radix Polygoni Multiflori [source] is the perennial winding of Polygonaceae liana.Root is elongated, the loose tuber of terminal one-tenth, and the appearance bronzing is to crineous.But the tuber of plant, rattan and leaf be hyoscine all.[function cures mainly] detoxifcation, loosening bowel to relieve constipation, eliminating carbuncle; Enrich and benefit essence and blood, black beard and hair, bone and muscle strengthening, invigorating the liver and kidney promote hemopoietic function, strengthen immunologic function.
Fructus Evodiae [source] is the almost ripe fruit of rutaceae Fructus Evodiae Evodia rutaecarpa.[function cures mainly] its bitter in the mouth hot in nature is cold, and the merit of heat radiation pain relieving, stopping nausea and vomiting by lowering the adverse flow of QI is arranged, and is used for the treatment of that the liver insufficiency of stomach is cold, the diseases such as the headache due to the cloudy turbid superinverse or gastralgia.
Radix Gymnematis Sylvestris [source] medical material Ji Yuan: be root or the browse of dicotyledon medicine asclepiadaceae plant Largeleaf Gymnema.[function cures mainly] clearing away heat and cooling blood; The evacuation of pus detumescence; The pain relieving granulation promoting.The main air pain of dampness syndrome; Laryngopharynx swelling and pain; Scrofula; Acute mastitis; Furuncle; Eczema; Innominate toxic swelling; Venom.
Gold waist [source] Saxifragaceae gold waist Chrysosplenium grayanum Maxim. is with all herbal medicine.[function cures mainly] promoting pus discharge and removing toxic substances.The blackhead furuncle is controlled in external.
The Radix Astragali [source] is the root of leguminous plant Radix Astagali or Radix Astragali.Remove fibrous root and root head, dry, section is given birth to and is used or processed with honey usefulness.[function cures mainly] has the enhancing human body immunity function, protects the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.
Rhizoma Dioscoreae [source] herbaceos perennial, stem is overgrow, and often is with purple, and tuber is cylindrical, and leaf is to life, and is avette or oval, flower milky, dioecism.Starch-containing and the protein of tuber.[function cures mainly] spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.Be used for insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.
The Radix Paeoniae Alba [source] is the root of dicotyledon medicine cohosh Radix Paeoniae (cultigen).The Peony Root of planting 3～4 years is removed rhizome and fibrous root, cleans, and scrapes off rough bark, enters in the boiling water and slightly boils, and the Chinese herbaceous peony root is felt like jelly, and pulls out and dries.[function cures mainly] nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.Control the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.
Flos Buddlejae [source] is dried floral or the alabastrum of loganiaceae plant Flos Buddlejae.[function cures mainly] sweet in the mouth, cold nature.Return liver, gallbladder meridian, heat clearing away nourishing the liver, improving acuity of vision and removing nebula.Be used for conjunctival congestion and swelling pain, many tear photophobia, the nebula of looking unfamiliar film, hepatasthenia dim eyesight, blurring of vision.
Radix Rehmanniae [source] is the fresh rhizome of Scrophulariaceae herbaceos perennial Radix Rehmanniae.The happiness temperature climate, more cold-resistant.The heat clearing away of [function cures mainly] clearing away heat and cooling blood is promoted the production of body fluid, and controls the epidemic febrile disease impairment of YIN, large hot excessive thirst, and crimson tongue, coma, macule is spitted blood, epistaxis, the asthenia hectic fever due to YIN-deficiency, hemoptysis is quenched one's thirst, constipation, metrorrhagia.
Flos Lonicerae [source] Flos Lonicerae is the caprifoliaceae plant alabastrum of Radix Ophiopogonis, contains chlorogenic acid, inositol, flavones ingredient etc.[function cures mainly] Flos Lonicerae has antiinflammatory and refrigeration function, and infected by influenza and various pathogens, skin pathomycete have inhibitory action, have reflected the heat-clearing toxin-expelling functions of Flos Lonicerae.It is cold in nature, sweet in the mouth, and the function heat clearing away, detoxifcation is applicable to the epidemic febrile disease heating, toxic-heat and blood stasis, the disease of the hyperactivity of toxic heat such as skin ulcer, carbuncle, furuncle and phyma.
Spica Prunellae [source] Spica Prunellae is flowers or the herb of labiate Spica Prunellae, includes triterpenoid saponin and glycoside thereof unit oleanolic acid, volatile oil and vitamin, potassium chloride etc.[function cures mainly] it is cold in nature, bitter in the mouth, suffering, and the function clearing away liver-fire, Disperse hepatic depression, blood pressure lowering is applicable to the conjunctival congestion and swelling pain due to the flaming up of liver-fire, ophthalmalgia, photophobia is shed tears, headache, dizzy etc.; Be used for the scrofula due to the phlegm-fire pent-up, goiter etc.
Cortex Moutan [source] is the root bark of Ranunculaceae Paeonia plant Paeonia suffruticosa, contains paeonol, paeonolide, volatile oil and plant sterol etc.[function cures mainly] Cortex Moutan reduces blood pressure, eases pain, calm, antiinflammatory and refrigeration function; Various pathogens there is stronger inhibitory action.It is cool in nature, bitter in the mouth, suffering, and the function heat clearing away, removing heat from blood and blood, the clear stasis of blood are applicable to thermal man's blood system, send out speckle, frightened pain, haematemesis, carbuncle and ulcer, the diseases such as traumatic injury.
The Rhizoma Anemarrhenae [source] is the rhizome of the liliaceous plant Rhizoma Anemarrhenae, contain multiple Saponin and Saponin it, contain in addition two kinds of flavonoids and become Mengiferin etc.[function cures mainly] Rhizoma Anemarrhenae has obvious refrigeration function, and Epidemic Hemorrhagic Fever, epidemic encephalitis type B, pulmonary tuberculosis hectic fever all have obvious curative effects.It is cold in nature, sweet in the mouth, hardship, and function clearing away heat-fire, nourshing Yin and drynsessmoistening prescription is applicable to lung-heat cough with asthma or cough due to yin deficiency, and dysphoria with smothery sensation is quenched one's thirst, hectic fever due to YIN-deficiency consumptive fever, dysuria, the diseases such as constipation due to dry stool.
Semen Cassiae [source] is stewed the seed of leaf Semen Cassiae or Semen Cassiae for leguminous plant, includes anthracene ester and anthraquinone glycoside, and obtusin and vitamin A etc. have reducing blood pressure and reduce the effect of serum cholesterol; Its cold nature, sweet in the mouth, hardship.[function cures mainly] function liver heat removing and eyesight improving, the diuretic relieving constipation is applicable to the puckery pain of conjunctival congestion due to liver-heat or the wind-heat of liver channel, the many tears of photophobia etc.; In addition to the treatment hypertension, hepatitis, cirrhotic ascites and habitual constipation etc. are also effective.
Cortex Lycii [source] is the root bark of Solanaceae Lycium plant Fructus Lycii, includes cinnamic acid, multiple aldehydes matter, betanin and linoleic acid etc.; Cortex Lycii has significant refrigeration function, and its decoct can make blood glucose reduce, and the serum cholesterol of reduction and lipotropic effect are arranged, and the preserved material of Cortex Lycii has the effect that reduces blood pressure significantly to animal.It is cold in nature, sweet in the mouth, light.[function cures mainly] removing heat from blood moves back steaming, and clear eliminating the pathogens from the lung heat is applicable to asthenia hectic fever night sweat, lung-heat cough with asthma, the haematemesis of bleeding due to blood-heat, epistaxis, carbuncle malignant boil and pulmonary tuberculosis and vascular hypertension etc.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of congenital pulmonary arteriovenous fistula, by selecting suitable medical material and proportioning thereof, reaches the purpose of safe and effective healing congenital pulmonary arteriovenous fistula.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for the treatment of congenital pulmonary arteriovenous fistula, it is characterized in that, be prepared from by the medical material of following weight proportion: 6 parts of Herb Gynostemmae Pentaphylli, 12 parts in Poria, 14 parts of Radix Polygoni Multiflori, 10 parts of Fructus Evodiaes, 8 parts of Radix Gymnematis Sylvestriss, 8 parts in golden waist, 14 parts of the Radixs Astragali, 12 parts of the Radix Paeoniae Albas, 12 parts of Flos Buddlejaes, 12 parts of Radix Rehmanniae, 12 parts of Flos Loniceraes, 14 parts of Spica Prunellaes, 8 parts of Cortex Moutans, 8 parts of the Rhizoma Anemarrhenaes, 14 parts of Semen Cassiaes, 8 parts of Cortex Lycii.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
11, physical data
The out-patient that the inventor collects 67 routine congenital pulmonary arteriovenous fistulas between year October in June, 2010-2011 altogether, age 12-28 year, course of disease 0.5-3.Be divided at random: treatment group 45 examples, blank group 22 examples.The data there was no significant differences such as two groups of ages, the state of an illness have comparability.
2, test method
2.1 the capsule that the oral the present invention for the treatment of group makes according to specific embodiment 1, sooner or later respectively once.15 days courses for the treatment of.
2.2 blank group oral placebo capsule, sooner or later respectively once.15 days courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, and the test chamber inspection is normal.Take a turn for the better: clinical symptom relief, the state of an illness is controlled, and lab testing improves or is normal.Invalid: clinical symptoms is without being clearly better or increasing the weight of.
3.2 treatment statistical result sees Table 1.
Table 1 liang group curative effect relatively
As seen, the medicine that makes of the present invention can safe and effectively be controlled congenital pulmonary arteriovenous fistula.
The specific embodiment
In order to understand better and to implement the present invention, further specify the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take by weighing: Herb Gynostemmae Pentaphylli 6 grams, Poria 12 grams, Radix Polygoni Multiflori 14 grams, Fructus Evodiae 10 grams, Radix Gymnematis Sylvestris 8 grams, golden waist 8 grams, the Radix Astragali 14 grams, the Radix Paeoniae Alba 12 grams, Flos Buddlejae 12 grams, Radix Rehmanniae 12 grams, Flos Lonicerae 12 grams, Spica Prunellae 14 grams, Cortex Moutan 8 grams, the Rhizoma Anemarrhenae 8 grams, Semen Cassiae 14 grams, Cortex Lycii 8 grams, add 8 times of water gagings, decocted 1.5 hours, and filtered; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, drying incapsulates shell, namely gets the capsule that meets 1 day consumption of normal adult.
Be used for the treatment of congenital pulmonary arteriovenous fistula.Oral, every bu is taken for twice sooner or later.
Specific embodiment 2
Take by weighing: Herb Gynostemmae Pentaphylli 6 grams, Poria 12 grams, Radix Polygoni Multiflori 14 grams, Fructus Evodiae 10 grams, Radix Gymnematis Sylvestris 8 grams, golden waist 8 grams, the Radix Astragali 14 grams, the Radix Paeoniae Alba 12 grams, Flos Buddlejae 12 grams, Radix Rehmanniae 12 grams, Flos Lonicerae 12 grams, Spica Prunellae 14 grams, Cortex Moutan 8 grams, the Rhizoma Anemarrhenae 8 grams, Semen Cassiae 14 grams, Cortex Lycii 8 grams, add 8 times of water gagings, decocted 1.5 hours, and filtered; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, drying is pulverized, and namely gets the powder that meets 1 day consumption of normal adult.
Be used for the treatment of congenital pulmonary arteriovenous fistula.Oral, every bu is taken for twice sooner or later.
Specific embodiment 3
Take by weighing: Herb Gynostemmae Pentaphylli 6 grams, Poria 12 grams, Radix Polygoni Multiflori 14 grams, Fructus Evodiae 10 grams, Radix Gymnematis Sylvestris 8 grams, golden waist 8 grams, the Radix Astragali 14 grams, the Radix Paeoniae Alba 12 grams, Flos Buddlejae 12 grams, Radix Rehmanniae 12 grams, Flos Lonicerae 12 grams, Spica Prunellae 14 grams, Cortex Moutan 8 grams, the Rhizoma Anemarrhenae 8 grams, Semen Cassiae 14 grams, Cortex Lycii 8 grams, add 8 times of water gagings, decocted 1.5 hours, and filtered; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, drying adds an amount of dextrin and correctives again, granulates according to this area common process, and packing can make the granule that meets 1 day consumption of normal adult.
Be used for the treatment of congenital pulmonary arteriovenous fistula.Oral, every bu is taken for twice sooner or later.
Claims (1)
1. Chinese medicine for the treatment of congenital pulmonary arteriovenous fistula, it is characterized in that, be prepared from by the medical material of following weight proportion: 6 parts of Herb Gynostemmae Pentaphylli, 12 parts in Poria, 14 parts of Radix Polygoni Multiflori, 10 parts of Fructus Evodiaes, 8 parts of Radix Gymnematis Sylvestriss, 8 parts in golden waist, 14 parts of the Radixs Astragali, 12 parts of the Radix Paeoniae Albas, 12 parts of Flos Buddlejaes, 12 parts of Radix Rehmanniae, 12 parts of Flos Loniceraes, 14 parts of Spica Prunellaes, 8 parts of Cortex Moutans, 8 parts of the Rhizoma Anemarrhenaes, 14 parts of Semen Cassiaes, 8 parts of Cortex Lycii.
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| CN 201310021201 CN103071027A (en) | 2013-01-14 | 2013-01-14 | Traditional Chinese medicine for treating congenital pulmonary arterio-venous fistula |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105106422A (en) * | 2015-09-28 | 2015-12-02 | 段平 | Medicine for treating internal arteriovenous fistula hardening and preparing method and device of medicine |
| CN105232673A (en) * | 2015-11-18 | 2016-01-13 | 山东大学第二医院 | Traditional Chinese medicine composition for treating internal arteriovenous fistula postoperative complications |
-
2013
- 2013-01-14 CN CN 201310021201 patent/CN103071027A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105106422A (en) * | 2015-09-28 | 2015-12-02 | 段平 | Medicine for treating internal arteriovenous fistula hardening and preparing method and device of medicine |
| CN105232673A (en) * | 2015-11-18 | 2016-01-13 | 山东大学第二医院 | Traditional Chinese medicine composition for treating internal arteriovenous fistula postoperative complications |
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Application publication date: 20130501 |