Background technology
Chronic atrophic gastritis (Chronic atrophic gastritis) is one of common disease of stomach.Refer to that the chronic gastritis that atrophic changes has occurred gastric mucosa, the intrinsic body of gland atrophy of mucosa that mucosa surface causes after repeatedly suffering damage, even disappears, the glutinous common pathological change thickening of flesh layer.This disease is one of digestive system commonly encountered diseases, frequently-occurring disease, accounts for 10%~30% in chronic gastritis.The intrinsic gland atrophy of the gastric mucosa of take on pathology changes as main, can be with intestinal epithelial metaplasia, inflammatory reaction and dysplasia.Clinical manifestation is that Abdeminal pain, belch, stomach poor appetite such as move back at the indigestion symptom.
For chronic atrophic gastritis, still lack at present the effective medicine of generally recognized as safe.
The present Research of the related medical material of Chinese medicine of the present invention is as follows:
Spica Prunellae [source] Spica Prunellae is flowers or the herb of labiate Spica Prunellae, includes triterpenoid saponin and glycoside unit oleanolic acid thereof, volatile oil and vitamin, potassium chloride etc.[function cures mainly] it is cold in nature, bitter in the mouth, pungent, and function clearing away liver-fire, Disperse hepatic depression, blood pressure lowering, is applicable to the conjunctival congestion and swelling pain due to flaming up of liver-fire, ophthalmalgia, photophobia is shed tears, headache, dizzy etc.; For the scrofula due to phlegm-fire pent-up, goiter etc.
Rhizoma Phragmitis [source] is the subterraneous stem of grass phragmites communis, includes Coixol, asparagine etc.It is cold in nature, sweet in the mouth.[function cures mainly] function clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, diuresis, be applicable to that consumption of body fluid caused by febrile disease, dysphoria with smothery sensation are thirsty, gastropyretic vomiting, dysphagic, regurgitation and treatment cough due to lung-heat, lung abscess etc.
Radix Scrophulariae [source] is the root of goatweed Radix Scrophulariae and Radix Scrophulariae, containing Radix Scrophulariae element, iridoid glycosides; Also containing volatile oil, alkaloid etc.; It is cold in nature, sweet in the mouth, hardship.[function cures mainly] nourishing YIN to lower pathogenic fire, removing pathogenic heat from blood and toxic substance from the body, is applicable to calentura excessive thirst, sends out speckle, hectic fever due to YIN-deficiency consumptive fever, the diseases such as not peaceful, spontaneous sweating, impairment of body fluid constipation and laryngopharynx swelling and pain of sleeping night.
Herb Gynostemmae Pentaphylli [source] perennial root plant, cold in nature, sweet in the mouth, has QI invigorating, calms the nerves, the effect of blood pressure lowering, main effective ingredient is polysaccharide, flavonoid, saponins and microelement kind.[function cures mainly] promotes body fat class substance metabolism, nutrition human body cell, has detoxicating, relieving inflammation effect simultaneously.
A kind of parasitic plant that colonizes in desert trees sacsaoul, red building root of Herba Cistanches [source], [function cures mainly] kidney-replenishing, benefiting essence-blood, can suppress the appearance of " yang deficiency " symptom, prevents from losing weight.Can effectively prevent, treat the diseases such as male dificiency of kidney sexual impotence, seminal emission premature ejaculation and woman's menoxenia, amenorrhea be infertile.
These product of Gecko [source] are flat lamellar, incidence and trunk minister 9~18cm, and incidence accounts for 1/3rd, and body is close by circle or the micro-glossiness thin squama of polygon, gas raw meat, taste is micro-salty.[function cures mainly] invigorating the lung and the kidney, helping inspiration to relieve asthma, supporing yang benefit essence.Treatment cough due to deficiency of the lung, suffers from a deficiency of the kidney and breathes heavily, and asthenia is breathed with cough.
Cortex Lycii [source] is the root bark of Solanaceae Lycium plant Fructus Lycii, includes cinnamic acid, multiple aldehydes matter, betanin and linoleic acid etc.; Cortex Lycii has significant refrigeration function, and its decoct can make blood glucose reduce, and has the serum cholesterol of reduction and lipotropic effect, and the preserved material of Cortex Lycii has the effect reducing blood pressure significantly to animal.It is cold in nature, sweet in the mouth, light.[function cures mainly] removing heat from blood, moves back steaming, and clear eliminating the pathogens from the lung heat, is applicable to asthenia hectic fever night sweat, lung-heat cough with asthma, the haematemesis of bleeding due to blood-heat, epistaxis, carbuncle malignant boil and pulmonary tuberculosis and vascular hypertension etc.
Fructus Forsythiae [source] Fructus Forsythiae is the fruit of Oleaceae plants Fructus Forsythiae, includes volatile oil, forsythol, flavonoid glycoside, alkaloid etc.; [function cures mainly] Fructus Forsythiae has broad-spectrum antibacterial action, and tell in antiinflammatory, town, diuresis and heart tonifying; Contained flavonoid glycoside can strengthen the density of blood capillary, its cold nature, bitter in the mouth, heat-clearing and toxic substances removing, mass dissipating and swelling eliminating, be applicable to warm, erysipelas, macule, carbuncle and ulcer toxic swelling and anaphylactoid purpura etc.
Radix Isatidis [source] Radix Isatidis is the root of Cruciferae Folium Isatidis platymiscium ancient name for Chinese cabbage orchid and careless Folium Isatidis, containing Radix Isatidis indigo glycoside, and isatan B, B--sitosterol etc.; There is remarkable antivirus action.Various pathogens is had to inhibitory action, and it is cold in nature, bitter in the mouth.[function cures mainly] heat-clearing and toxic substances removing, removing heat from blood, sore-throat relieving, is applicable to influenzal encephalitis, encephalitis B, pneumonia, erysipelas, pyretic toxicity and sends out speckle, acute catarrhal conjunctivitis, herpes etc.
Spica Prunellae [source] Spica Prunellae is flowers or the herb of labiate Spica Prunellae, includes triterpenoid saponin and glycoside unit oleanolic acid thereof, volatile oil and vitamin, potassium chloride etc.[function cures mainly] it is cold in nature, bitter in the mouth, pungent, and function clearing away liver-fire, Disperse hepatic depression, blood pressure lowering, is applicable to the conjunctival congestion and swelling pain due to flaming up of liver-fire, ophthalmalgia, photophobia is shed tears, headache, dizzy etc.; For the scrofula due to phlegm-fire pent-up, goiter etc.
Gold waist [source] Saxifragaceae gold waist Chrysosplenium grayanum Maxim., with all herbal medicine.[function cures mainly] promoting pus discharge and removing toxic substances.Blackhead furuncle is controlled in external.
Radix Angelicae Sinensis [source] formal name used at school: Angelica sinensis, herbaceos perennial, stem band purple.All there is cultivation various places.Root can be used as medicine, and is one of the most frequently used Chinese medicine.[function cures mainly] anti-hypoxia, regulate body's immunity, anticancer, improve looks, enrich blood invigorate blood circulation, antibacterial, arteriosclerosis.
Radix Polygoni Multiflori [source] is the perennial winding of Polygonaceae liana.Root is elongated, and end becomes loose tuber, and appearance bronzing is to crineous.The tuber of plant, rattan and leaf all can hyoscines.[function cures mainly] removing toxic substances, loosening bowel to relieve constipation, eliminating carbuncle; Enrich and benefit essence and blood, black beard and hair, bone and muscle strengthening, invigorating the liver and kidney.Promote hemopoietic function, strengthen immunologic function
Bulbus Lilii [source] Liliaceae lilium perennial herb bulbous plant, it is spent, squamous stem all can be used as medicine, and is a kind of flowers of dietotherapeutic.[function cures mainly] cold nature is flat, have relieve inflammation or internal heat, lung moistening, the effect of calming the nerves.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of chronic atrophic gastritis, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing chronic atrophic gastritis.
In order to achieve the above object, the present invention is by the following technical solutions:
A Chinese medicine for the treatment of chronic atrophic gastritis, is characterized in that, by the medical material of following weight proportion, is prepared from: 10 parts of Spica Prunellaes,
12 parts of Rhizoma Phragmitiss, 14 parts of Radix Scrophulariaes, 8 parts of Herb Gynostemmae Pentaphylli, 10 parts of Herba Cistanches, 6 parts of Geckos, 7 parts of Cortex Lycii, 6 parts of Fructus Forsythiaes, 8 parts of Radix Isatidis, 9 parts of Spica Prunellaes, 5 parts, golden waist, 4 parts of Radix Angelicae Sinensis, 6 parts of Radix Polygoni Multiflori, 7 parts of Bulbus Liliies.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
1, physical data
Inventor collects the out-patient of 80 routine chronic atrophic gastritis for 2009 altogether between year JIUYUE of March-2010, age 19-54 year, course of disease 0.5-7.Be divided at random: treatment group 50 examples, blank group 30 examples.The data there was no significant differences such as two groups of ages, the state of an illness, have comparability.
2, test method
The capsule that the oral the present invention of 2.1 treatment group makes according to specific embodiment 1, sooner or later respectively once.30 days courses for the treatment of.
2.2 blank group oral placebo capsules, sooner or later respectively once.30 days courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, and test chamber inspection is normal.Take a turn for the better: clinical symptom relief, the state of an illness is controlled, and lab testing improves or is normal.Invalid: clinical symptoms is without being clearly better or increasing the weight of.
3.2 treatment statistical results are in Table 1.
Table 1 liang group curative effect comparison
Group |
n |
Recovery from illness |
Take a turn for the better |
Invalid |
Total effective rate (%) |
Treatment group |
50 |
10(20%) |
34(68%) |
6(12%) |
88% |
Blank group |
30 |
0 |
5(16.7%) |
25(83.3%) |
16.7% |
Visible, the medicine that the present invention makes can safe and effectively be controlled chronic atrophic gastritis.
The specific embodiment
In order to understand better and to implement the present invention, below in conjunction with specific embodiment, further illustrate the present invention.
specific embodiment 1
Take: 10 grams of Spica Prunellaes, 12 grams of Rhizoma Phragmitiss, 14 grams of Radix Scrophulariaes, 8 grams of Herb Gynostemmae Pentaphylli, 10 grams of Herba Cistanches, 6 grams of Geckos, 7 grams of Cortex Lycii, 6 grams of Fructus Forsythiaes, 8 grams of Radix Isatidis, 9 grams of Spica Prunellaes, 5 grams, golden waist, 4 grams of Radix Angelicae Sinensis, 6 grams of Radix Polygoni Multiflori, 7 grams of Bulbus Liliies, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, must meet the capsule of 1 day consumption of normal adult.
Be used for the treatment of chronic atrophic gastritis.Oral, every bu is taken for twice sooner or later.
specific embodiment 2
Take: 10 grams of Spica Prunellaes, 12 grams of Rhizoma Phragmitiss, 14 grams of Radix Scrophulariaes, 8 grams of Herb Gynostemmae Pentaphylli, 10 grams of Herba Cistanches, 6 grams of Geckos, 7 grams of Cortex Lycii, 6 grams of Fructus Forsythiaes, 8 grams of Radix Isatidis, 9 grams of Spica Prunellaes, 5 grams, golden waist, 4 grams of Radix Angelicae Sinensis, 6 grams of Radix Polygoni Multiflori, 7 grams of Bulbus Liliies, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, concentrated, dry, pulverize, must meet the powder of 1 day consumption of normal adult.
Be used for the treatment of chronic atrophic gastritis.Oral, every bu is taken for twice sooner or later.
specific embodiment 3
Take: 10 grams of Spica Prunellaes, 12 grams of Rhizoma Phragmitiss, 14 grams of Radix Scrophulariaes, 8 grams of Herb Gynostemmae Pentaphylli, 10 grams of Herba Cistanches, 6 grams of Geckos, 7 grams of Cortex Lycii, 6 grams of Fructus Forsythiaes, 8 grams of Radix Isatidis, 9 grams of Spica Prunellaes, 5 grams, golden waist, 4 grams of Radix Angelicae Sinensis, 6 grams of Radix Polygoni Multiflori, 7 grams of Bulbus Liliies, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, dry, then add appropriate dextrin and correctives, and according to this area common process, to granulate, packing, can make the granule that meets 1 day consumption of normal adult.
Be used for the treatment of chronic atrophic gastritis.Oral, every bu is taken for twice sooner or later.